Dr. Frode S. Berven (Ph.D.) is the head of the Proteomics Unit at the University of Bergen.

Berven completed his Masters degree at Department of Molecular Biologi, UiB, Ph.D. in bioinformatics at the Department of Informatics, UiB, and post doctor at the Institute of Medicine, UiB, and at the Proteomics Platform at the Broad Institute of MIT and Harvard.

He is working in the field of mass spectrometry based quantitative proteomics with emphaisis on biomarker disocovery and verification in cerebrospinal fluid of patients with multiple sclerosis.

1.      A    Berle M, Wester KG, Ulvik RJ, Kroksveen AC, Haaland OA, Amiry-Moghaddam M, Berven FS, Helland CA. “Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults.” Cerebrospinal fluid research,  2010 June 10;7:8.

2.      A    Rajalahti T, Kroksveen AC, Arneberg R, Berven FS, Vedeler CA, Myhr KM, Kvalheim OM. “A multivariate approach to reveal biomarker signatures for disease classification: application to mass spectral profiles of cerebrospinal fluid from patients with multiple sclerosis.” Journal of Proteome Research, 2010 July 2;9(7):3608-20.

3.      A    Berven FS. Ahmad R. Clauser K. Carr SA. “Optimizing performance of glycopeptides capture for plasma proteomics”. Journal of Proteome Research, 2010 April 5;9(4):1706-15.

4.      A    Teunissen CE, Tumani HT, Bennett JL, Berven FS, ++, Deisenhammer F, Giovannoni G. “Short commentary on 'a consensus protocol for the standardization of cerebrospinal fluid collection and biobanking'. Multiple Sclerosis, 2010; 16(2) 129-32.

5.      A    Teunissen CE, Tumani HT, JL. Bennett, FS. Berven, ++, M. Comabella, D., C. Wolf, H. Tumani, B. Hemmer, F. Deisenhammer. “A consensus protocol for standardisation of CSF sampling and biobanking”. Neurology, 2009;73;1914-1922.

6.      A    Tumani H, Hartung HP, Hemmer B, Teunissen C, Deisenhammer F, Giovannoni G, Zettl UK, Altintas A, Bennett JL, Berven FS, Petzold A, Rajda C, Rejdak K, van Pesch V, Waubant E. “Cerebrospinal fluid biomarkers in multiple sclerosis”. Neurobiol Dis. 2009 Aug;35(2):117-27.

7.      A    Rajalahti T. Arneberg R. Berven FS. Myhr KM. Ulvik RJ. Kvalheim OM. “Biomarker discovery in mass spectral profiles by means of selectivity ratio plot”. Chemometrics and Intelligent Laboratory Systems. 2008 August

8.      A    Målen, H. Berven, FS. Søfteland, T. Arntzen, ØM. D’Santos, C. Wiker, H. “Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies”. Proteomics. 2008 may 8(9) 1859-70.

9.      A    Rajalahti, T. Arneberg, R. Berven, FS. Kroksveen, AC. Berle, M. Flikka, K. Myhr, KM. Vedeler, C. Kvalheim, OM. Ulvik, RJ. “Pretreatment of mass spectral profiles: Application to proteomic data”. Analytical Chemistry. 2007 August 79 (18) 7014-7026.

10.   A    Berven, FS. Kroksveen, AC. Berle, M. Flikka, K. Myhr, KM. Vedeler, C. Arneberg, R. Rajalahti, T. Kvalheim, OM. Ulvik, RJ. “Pre-analytical influence on the low molecular weight cerebro spinal fluid proteome”. Proteomics Clinical Applications. 2007 July 1(7) 699-711. Selected as an “In this issue” highlighted article.

11.   A    Målen, H. Berven, FS. Fladmark, K. Wiker, H. “Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv”.  Proteomics. 2007 May 7(10) 1702-18. Selected as an “In this issue” highlighted article.

12.   A    Aukrust I, Evensen L, Hollas H, Berven F, Atkinson RA, Trave G, Flatmark T, Vedeler A. “Engineering, biophysical  characterization and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation”. Journal of molecular biology. 2006 Oct 20;363(2):469-81.

13.   A    Berven FS, Flikka K, Berle M, Vedeler C, Ulvik RJ. “Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis”. Curr Pharm Biotechnol. 2006 Jun;7(3):147-58. Review.

14.   A    Berven, FS. Karlsen, OA. Straume, AH. Flikka, K. Murrell, JC. Lillehaug, JR. Fjellbirkeland, A. Eidhammer, I. Jensen, HB. ”Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools”. Arch Microbiol. 2006 Feb;184(6):362-77. Epub 2005 Nov 26.

15.   A    Karlsen, OA. Ramsevik, L. Bruseth, LJ. Larsen O. Brenner, A. Berven, FS. Jensen, HB. Lillehaug, JR. “Characterization of a prokaryotic haemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath)”. FEBS journal 2005, Volume 272, Issue10, Pages 2428-2440.

16.   A    Berven, FS. Flikka, K. Jensen, HB. Eidhammer, I. “BOMP: a program to predict integral b-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria”. Nucleic Acids Research 2004, Volume 32, Web Server Issue, Pages W394-399.

17.   A    Karlsen, OA. Berven, FS. Stafford, GP. Larsen, O. Murrell, JC. Jensen, HB. Fjellbirkeland, A. “The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium”. Applied Environmental Microbiology, April 2003, Volume 69, Issue 4, Pages 2386-2388.

18.   A    Berven, FS. Karlsen OA. Murrell, JC. Jensen, HB. “Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure”. Electrophoresis, February 2003, Volume 24, Issue 4, Pages 757-761.

 

2024

• Tijms, Betty M.; Vromen, Ellen M.; Mjaavatten, Olav et al. (2024). Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles. (external link)
• Eidem, Live Egeland; Birkeland, Even; Austdal, Marie et al. (2024). Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid. (external link)
• Lereim, Ragnhild Reehorst; Nytrova, Petra; Guldbrandsen, Astrid et al. (2024). Natalizumab promotes anti-inflammatory and repair effects in multiple sclerosis. (external link)

2023

• Barakat, Ahmed Samy Mohamed Ali; Birkeland, Even; Jørstad, Melissa Davidsen et al. (2023). Proteomic analysis of peripheral blood mononuclear cells isolated from patients with pulmonary tuberculosis: A pilot study from Zanzibar, Tanzania. (external link)
• Bartaula-Brevik, Sushma; Leitch, Calum; Valladares, Maria del Carmen Hernandez et al. (2023). Vacuolar ATPase Is a Possible Therapeutic Target in Acute Myeloid Leukemia: Focus on Patient Heterogeneity and Treatment Toxicity. (external link)

2022

• Neset, Lasse; Takayidza, Gracious; Berven, Frode Steingrimsen et al. (2022). Comparing Efficiency of Lysis Buffer Solutions and Sample Preparation Methods for Liquid Chromatography–Mass Spectrometry Analysis of Human Cells and Plasma. (external link)
• Yilmaz, Ozlem; Mangor-Jensen, Anders; Harboe, Torstein et al. (2022). Quantitative proteome profiling reveals molecular hallmarks of egg quality in Atlantic halibut: impairments of transcription and protein folding impede protein and energy homeostasis during early development. (external link)
• Teodora, Paunas Flavia; Finne, Kenneth; Leh, Sabine et al. (2022). Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN. (external link)
• Cappelletti, Chiara; Eriksson, Anna Maria; Brorson, Ina Skaara et al. (2022). Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls. (external link)

2021

• Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria et al. (2021). Proteomic Characterization of Spontaneous Stress-Induced In Vitro Apoptosis of Human Acute Myeloid Leukemia Cells; Focus on Patient Heterogeneity and Endoplasmic Reticulum Stress. (external link)
• Mosleth, Ellen Færgestad; Vedeler, Christian Alexander; Liland, Kristian Hovde et al. (2021). Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis. (external link)
• Aasebø, Elise; Brenner, Annette; Birkeland, Even et al. (2021). The constitutive extracellular protein release by acute myeloid leukemia cells—A proteomic study of patient heterogeneity and its modulation by mesenchymal stromal cells. (external link)
• Oveland, Eystein; Ahmad, Intakhar; Lereim, Ragnhild Reehorst et al. (2021). Cuprizone and EAE mouse frontal cortex proteomics revealed proteins altered in multiple sclerosis. (external link)
• Grønningsæter, Ida Sofie; Reikvam, Håkon; Aasebø, Elise et al. (2021). Effects of the autophagy‐inhibiting agent chloroquine on acute myeloid leukemia cells; characterization of patient heterogeneity. (external link)
• Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria et al. (2021). Proteomic comparison of bone marrow derived osteoblasts and mesenchymal stem cells. (external link)
• Vareecal Joseph, Justin; Magaut, Capucine R.; Storevik, Simon Humberto et al. (2021). TGF-β promotes microtube formation in glioblastoma through thrombospondin 1. (external link)
• Hernandez-Valladares, Maria; Wangen, Rebecca; Aasebø, Elise et al. (2021). Proteomic studies of primary acute myeloid leukemia cells derived from patients before and during disease-stabilizing treatment based on all-trans retinoic acid and valproic acid. (external link)
• Bjørkum, Alvhild Alette; Duran, Ana Carrasco; Berven, Frode Steingrimsen et al. (2021). Human blood serum proteome changes after 6 hours of sleep deprivation at night. (external link)
• Røberg-Larsen, Hanne; Lundanes, Elsa; Nyman, Tuula Anneli et al. (2021). Liquid chromatography, a key tool for the advancement of single-cell omics analysis. (external link)
• Aasebø, Elise; Brenner, Annette; Hernandez-Valladares, Maria et al. (2021). Patient Heterogeneity in Acute Myeloid Leukemia: Leukemic Cell Communication by Release of Soluble Mediators and Its Effects on Mesenchymal Stem Cells. (external link)

2020

• Aasebø, Elise; Birkeland, Even; Selheim, Frode et al. (2020). The extracellular bone marrow microenvironment — a proteomic comparison of constitutive protein release by in vitro cultured osteoblasts and mesenchymal stem cells. (external link)
• Haaland, Ingvild; Aardal, Marit Elisabeth; Berven, Frode Steingrimsen et al. (2020). Changes in the induced sputum proteome during COPD exacerbations. (external link)
• Hernandez-Valladares, Maria; Aasebø, Elise; Berven, Frode et al. (2020). Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation. (external link)
• Aasebø, Elise; Berven, Frode; Bartaula-Brevik, Sushma et al. (2020). Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia. (external link)
• Guldbrandsen, Astrid; Lereim, Ragnhild Reehorst; Jacobsen, Mari et al. (2020). Development of robust targeted proteomics assays for cerebrospinal fluid biomarkers in multiple sclerosis. (external link)
• Aasebø, Elise; Berven, Frode; Hovland, Randi et al. (2020). The progression of acute myeloid leukemia from first diagnosis to chemoresistant relapse: A comparison of proteomic and phosphoproteomic profiles. (external link)

2019

• Brenner, Annette; Aasebø, Elise; Hernandez-Valladares, Maria et al. (2019). The capacity of long-term in vitro proliferation of acute myeloid leukemia cells supported only by exogenous cytokines is associated with a patient subset with adverse outcome. (external link)
• Berge, Tone; Eriksson, Anna; Brorson, Ina S et al. (2019). Quantitative proteomic analyses of CD4+ and CD8+ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls.. (external link)
• Aasebø, Elise; Hernandez-Valladares, Maria; Selheim, Frode et al. (2019). Proteomic profiling of primary human acute myeloid leukemia cells does not reflect their constitutive release of soluble mediators. (external link)
• Guldbrandsen, Astrid; Farag, Yehia Mohamed Mokhtar; Lereim, Ragnhild Reehorst et al. (2019). Essential Features and Use Cases of the Cerebrospinal Fluid Proteome Resource (CSF-PR). (external link)
• Ahmad, Rushdy; Xie, Liangxia; Pyle, Margaret et al. (2019). A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough. (external link)
• Aasebø, Elise; Berven, Frode; Bartaula-Brevik, Sushma et al. (2019). Proteome and phosphoproteome changes associated with prognosis in acute myeloid leukemia. (external link)
• Teodora, Paunas Flavia; Finne, Kenneth; Leh, Sabine Maria et al. (2019). Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli. (external link)
• Nepstad, Ina; Hatfield, Kimberley Joanne; Grønningsæter, Ida Sofie et al. (2019). Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.. (external link)
• Zhang-James, Yanli; Vaudel, Marc; Mjaavatten, Olav et al. (2019). Effect of disease-associated SLC9A9 mutations on protein–protein interaction networks: implications for molecular mechanisms for ADHD and autism. (external link)
• Berge, Tone; Eriksson, Anna; Brorson, Ina Skaara et al. (2019). Quantitative proteomic analyses of CD4+ and CD8+ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls . (external link)
• Hernandez-Valladares, Maria; Wangen, Rebecca; Berven, Frode et al. (2019). Protein post-translational modification crosstalk in acute myeloid leukemia calls for action. (external link)
• Burger, Bram; Lereim, Ragnhild Reehorst; Berven, Frode et al. (2019). Detecting single amino acids and small peptides by combining isobaric tags and peptidomics. (external link)

2018

• Eriksson, Anna; Brorson, Ina Skaara; Høgestøl, Einar August et al. (2018). Proteomic profiling of CD4+ T cells from MS patients show increased activity of T cell activation pathways (compared to healthy controls) . (external link)
• Berge, Tone; Brorson, Ina Skaara; Høgestøl, Einar August et al. (2018). Proteomic profiling of CD4+ and CD8+ T cells from multiple sclerosis patients and healthy controls. (external link)
• Berge, Tone; Eriksson, Anna; Brorson, Ina Skaara et al. (2018). Proteomic profiling of CD4+ and CD8+ T cells from multiple sclerosis patients and healthy controls. (external link)
• Nepstad, Ina; Hatfield, Kimberley Joanne; Aasebø, Elise et al. (2018). Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic and transcriptomic comparison. (external link)
• Jacobsen, Mari; Berven, Frode; Guldbrandsen, Astrid (2018). Development and Use of Mass Spectrometry Based Quantitative Proteomics Assays for Multiple Sclerosis Biomarker Candidates. (external link)
• Berge, Tone; Eriksson, Anna; Brorson, Ina Skaara et al. (2018). Proteomic profiling of T cells from multiple sclerosis patients and healthy controls. (external link)
• Yang, Mingxing; Kohler, Maxie; Heyder, Tina et al. (2018). Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype. (external link)
• Yang, Mingxing; Kohler, Maxie; Heyder, Tina et al. (2018). Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD. (external link)

2017

• Bjørkum, Alvhild Alette; Oveland, Eystein; Stuhr, Linda Elin Birkhaug et al. (2017). Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. (external link)
• Hernandez-Valladares, Maria; Vaudel, Marc; Selheim, Frode et al. (2017). Proteogenomics approaches for studying cancer biology and their potential in the identification of acute myeloid leukemia biomarkers. (external link)
• Forthun, Rakel Brendsdal; Aasebø, Elise; Rasinger, Josef Daiel et al. (2017). Phosphoprotein DIGE profiles reflect blast differentiation, cytogenetic risk stratification, FLT3/NPM1 mutations and therapy response in acute myeloid leukaemia. (external link)
• Oveland, Eystein; Nystad, Agnes Elisabeth; Berven, Frode et al. (2017). 1,25-Dihydroxyvitamin-D3 induces brain proteomic changes in cuprizone mice during remyelination involving calcium proteins. (external link)
• Verheggen, Kenneth; Ræder, Helge; Berven, Frode et al. (2017). Anatomy and evolution of database search engines—a central component of mass spectrometry based proteomic workflows. (external link)
• Yadetie, Fekadu; Oveland, Eystein; Døskeland, Anne Marie Simonne et al. (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. (external link)
• Nygaard, Gyrid; Herfindal, Lars; Sivertsen Åsrud, Kathrine et al. (2017). Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. (external link)
• Paunas, Theodora Ioana; Finne, Kenneth; Leh, Sabine Maria et al. (2017). Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy. (external link)
• Brenner, Annette; Aasebø, Elise; Hernandez-Valladares, Maria et al. (2017). Rethinking the role of osteopontin in human acute myeloid leukemia. (external link)
• Kroksveen, Ann Cathrine; Guldbrandsen, Astrid; Vaudel, Marc et al. (2017). In-depth cerebrospinal fluid quantitative proteome and deglycoproteome analysis: presenting a comprehensive picture of pathways and processes affected by multiple sclerosis. (external link)
• Yadetie, Fekadu; Eide, Marta; Oveland, Eystein et al. (2017). Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. (external link)

2016

• Finne, Kenneth; Marti, Hans-Peter; Leh, Sabine Maria et al. (2016). Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. (external link)
• Aasebø, Elise; Forthun, Rakel Brendsdal; Berven, Frode et al. (2016). Global cell proteome profiling, phospho-signaling and quantitative proteomics for identification of new biomarkers in acute myeloid leukemia patients. (external link)
• Vaudel, Marc; Barsnes, Harald; Bjerkvig, Rolf et al. (2016). Practical considerations for omics experiments in biomedical sciences. (external link)
• Hernandez-Valladares, Maria; Aasebø, Elise; Mjaavatten, Olav et al. (2016). Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients. (external link)
• Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc et al. (2016). Freezing effects on the acute myeloid leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows. (external link)
• Guldbrandsen, Astrid; Berven, Frode; Kroksveen, Ann Cathrine et al. (2016). Proteome and deglycopeptide analyses of neurologically healthy and multiple sclerosis affected cerebrospinal fluid: Mass spectrometry experiments, literature mining and data sharing . (external link)
• Aasebø, Elise; Berven, Frode (2016). Mass spectrometry-based proteome quantification in leukemic cells from acute myeloid leukemia patients. (external link)
• Vaudel, Marc; Barsnes, Harald; Ræder, Helge et al. (2016). Using Proteomics Bioinformatics Tools and Resources in Proteogenomic Studies. (external link)
• Hernandez Sanchez, Luis Francisco; Aasebø, Elise; Selheim, Frode et al. (2016). Systemic Analysis of Regulated Functional Networks. (external link)
• Lereim, Ragnhild Reehorst; Oveland, Eystein; Xiao, Y. et al. (2016). The Brain Proteome of the Ubiquitin Ligase Peli1 Knock-Out Mouse during Experimental Autoimmune Encephalomyelitis. (external link)
• Guldbrandsen, Astrid; Farag, Yehia Mohamed Mokhtar; Kroksveen, Ann Cathrine et al. (2016). CSF-PR 2.0: an interactive literature guide to quantitative cerebrospinal fluid mass spectrometry data from neurodegenerative disorders. (external link)
• Muth, Thilo; Rapp, Erdmann; Berven, Frode et al. (2016). Tandem Mass Spectrum Sequencing: An Alternative to Database Search Engines in Shotgun Proteomics. (external link)
• Yadetie, Fekadu; Bjørneklett, Silje; Garberg, Hilde Kristin et al. (2016). Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. (external link)
• Karlsen, Odd Andre; Yadetie, Fekadu; Eide, Marta et al. (2016). Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153. (external link)
• Yadetie, Fekadu; Eide, Marta; Oveland, Eystein et al. (2016). Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 . (external link)
• Opsahl, Jill Anette; Vaudel, Marc; Guldbrandsen, Astrid et al. (2016). Label-free analysis of human cerebrospinal fluid addressing various normalization strategies and revealing protein groups affected by multiple sclerosis. (external link)
• Vaudel, Marc; Verheggen, Kenneth; Csordas, Attila et al. (2016). Exploring the potential of public proteomics data. (external link)
• Tveit, Vegard; Berven, Frode; Guldbrandsen, Astrid et al. (2016). Glycopeptide analysis and glycan structure inference from mass spectrometry data-Investigating the potential of computational glycan structure analysis in biomedical research. (external link)
• Hernandez-Valladares, Maria; Aasebø, Elise; Selheim, Frode et al. (2016). Selecting Sample Preparation Workflows for Mass Spectrometry-Based Proteomic and Phosphoproteomic Analysis of Patient Samples with Acute Myeloid Leukemia . (external link)
• Lereim, Ragnhild Reehorst; Oveland, Eystein; Berven, Frode et al. (2016). Visualization, Inspection and Interpretation of Shotgun Proteomics Identification Results. (external link)
• Verheggen, Kenneth; Martens, Lennart; Berven, Frode et al. (2016). Database Search Engines: Paradigms, Challenges and Solutions.. (external link)
• Aasebø, Elise; Berven, Frode; Selheim, Frode et al. (2016). Interpretation of Quantitative Shotgun Proteomic Data. (external link)
• Guldbrandsen, Astrid; Barsnes, Harald; Kroksveen, Ann Cathrine et al. (2016). A Simple Workflow for Large Scale Shotgun Glycoproteomics. (external link)

2015

• Vaudel, Marc; Burkhart, Julia M.; Zahedi, René P. et al. (2015). PeptideShaker enables reanalysis of MS-derived proteomics data sets. (external link)
• Wang, Xiangdong; Zhang, Yong; Nilsson, Carol L. et al. (2015). Association of chromosome 19 to lung cancer genotypes and phenotypes. (external link)
• Wang, Xiangdong; Zhang, Yong; Nilsson, Carol L. et al. (2015). Erratum to: Association of chromosome 19 to lung cancer genotypes and phenotypes. (external link)
• Oveland, Eystein; Muth, Thilo; Rapp, Erdmann et al. (2015). Viewing the proteome: How to visualize proteomics data?. (external link)
• Horvatovich, Péter; Végvári, Ákos; Saul, Justin et al. (2015). In vitro transcription/translation system: A versatile tool in the search for missing proteins. (external link)
• Wheelock, Åsa M.; Paulson, Linda; Litton, Jan-Eric et al. (2015). The EuPA Biobank Initiative: Meeting the future challenges of biobanking in proteomics & systems medicine. (external link)
• Farag, Yehia Mohamed Mokhtar; Berven, Frode; Jonassen, Inge et al. (2015). Distributed and interactive visual analysis of omics data. (external link)
• Kroksveen, Ann Cathrine; Opsahl, Jill Anette; Guldbrandsen, Astrid et al. (2015). Cerebrospinal fluid proteomics in multiple sclerosis. (external link)
• Kroksveen, Ann Cathrine; Jaffe, Jacob D.; Aasebø, Elise et al. (2015). Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis. (external link)
• Nilsson, Carol L.; Mostovenko, Ekaterina; Lichti, Cheryl F. et al. (2015). Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. (external link)

2014

• Lereim, Ragnhild Reehorst; Oveland, Eystein; Berven, Frode (2014). Establishment and usage of quantitative brain proteomics to investigate the role of Peli1 E3 ubiquitin ligase in the EAE mouse model of multiple sclerosis. (external link)
• Mahootchi, Elaheh; Kroksveen, Ann Cathrine; Opsahl, Jill Anette et al. (2014). Label-free proteomics analysis of plasma to discover proteins with differential abundance between multiple sclerosis patients and controls. (external link)
• Vaudel, Marc; Venne, A. Saskia; Berven, Frode et al. (2014). Shedding light on black boxes in protein identification. (external link)
• Lichti, Cheryl F.; Liu, Huiling; Shavkunov, Alexander S. et al. (2014). Integrated chromosome 19 transcriptomic and proteomic data sets derived from glioma cancer stem-cell lines. (external link)
• Haaland, Ingvild; Opsahl, Jill Anette; Berven, Frode et al. (2014). Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia. (external link)
• Finne, Kenneth; Vethe, Heidrun; Skogstrand, Trude et al. (2014). Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats. (external link)
• Vaudel, Marc; Barsnes, Harald; Martens, Lennart et al. (2014). Bioinformatics for Proteomics: Opportunities at the interface between the scientists, their experiments and the community. (external link)
• Bjørlykke, Yngvild; Vethe, Heidrun; Vaudel, Marc et al. (2014). Carboxyl-ester lipase maturity-onset diabetes of the young disease protein biomarkers in secretin-stimulated duodenal juice. (external link)
• Aasebø, Elise; Opsahl, Jill Anette; Bjørlykke, Yngvild et al. (2014). Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome. (external link)
• Guldbrandsen, Astrid; Vethe, Heidrun; Farag, Yehia Mohamed Mokhtar et al. (2014). In-depth characterization of the cerebrospinal fluid (CSF) proteome displayed through the CSF proteome resource (CSF-PR). (external link)
• Aasebø, Elise; Vaudel, Marc; Mjaavatten, Olav et al. (2014). Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines. (external link)
• Helgeland, Erik; Breivik, Lars Ertesvåg; Vaudel, Marc et al. (2014). Exploring the human plasma proteome for humoral mediators of remote ischemic preconditioning - A word of caution. (external link)

2013

• Kroksveen, Ann Cathrine; Aasebø, Elise; Vethe, Heidrun et al. (2013). Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM. (external link)
• Finne, Kenneth; Skogstrand, Trude; Tenstad, Olav et al. (2013). Proteomic analysis of outer and juxtamedullary cortex of non-clipped kidneys in 2K1C hypertensive rats. (external link)
• Berle, Magnus Foldal; Kroksveen, Ann Cathrine; Garberg, Hilde Kristin et al. (2013). Quantitative proteomics comparison of arachnoid cyst fluid and cerebrospinal fluid collected perioperatively from arachnoid cyst patients. (external link)
• Teunissen, Charlotte E.; Menge, Til; Altintas, Ayse et al. (2013). Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis. (external link)
• Malm, Johan; Fehninger, T.E.; Danmyr, Pia et al. (2013). Developments in biobanking workflow standardization providing sample integrity and stability. (external link)
• Nilsson, Carol L.; Berven, Frode; Selheim, Frode et al. (2013). Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium. (external link)

2012

• Aye, Thin Thin; Low, Teck Yew; Bjørlykke, Yngvild et al. (2012). Use of stable isotope dimethyl labeling coupled to selected reaction monitoring to enhance throughput by multiplexing relative quantitation of targeted proteins. (external link)
• Berven, Frode; Vethe, Heidrun; Selheim, Frode (2012). Mass spectrometry-based proteomics of human cerebrospinal fluid Biomarker discovery and verification in multiple sclerosis. (external link)
• Guldbransen, Astrid; Berven, Frode; Selheim, Frode (2012). Glycoproteomics in Human Cerebrospinal Fluid Mapping the CSF Proteome, and Biomarker Discovery and Qualification in Multiple Sclerosis. (external link)
• Kroksveen, Ann Cathrine; Guldbrandsen, Astrid; Vedeler, Christian A. et al. (2012). Cerebrospinal fluid proteome comparison between multiple sclerosis patients and controls. (external link)
• Mjaavatten, Olav; Nygaard, Gyrid; Berven, Frode et al. (2012). Minimization of side reactions during Lys Tag derivatization of C-terminal lysine peptides. (external link)
• Haugland, Gyri Teien; Rønneseth, Anita; Berven, Frode et al. (2012). Global proteomic analyses of fish leukocytes during pathogen infections.. (external link)

2011

• Eijsink, Vincent; Berven, Frode (2011). The field of proteomics in Norway. (external link)
• Berle, Magnus Foldal; Kroksveen, Ann Cathrine; Haaland, Øystein et al. (2011). Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid. (external link)
• Arntzen, Magnus; Koehler, Christian; Barsnes, Harald et al. (2011). IsobariQ: Software for isobaric quantitative proteomics using IPTL, iTRAQ and TMT. (external link)
• Kroksveen, Ann Cathrine; Opsahl, Jill Anette; Aye, Thin Thin et al. (2011). Proteomics of human cerebrospinal fluid: Discovery and verification of disease biomarker candidates in neurodegenerative diseases using quantitative proteomics. (external link)
• Arntzen, Magnus; Koehler, Christian; Barsnes, Harald et al. (2011). IsobariQ: Software for Isobaric Quantitative Proteomics using IPTL, iTRAQ, and TMT. (external link)
• Kamil, Atif; Falk, Knut; Sharma, Animesh et al. (2011). A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. (external link)
• Karlsen, Odd Andre; Berven, Frode; Jensen, Harald B et al. (2011). METHANOTROPH OUTER MEMBRANE PREPARATION. (external link)
• Karlsen, Odd Andre; Berven, Frode; Bagstevold, June Iren Larsen| et al. (2011). Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. (external link)
• Vaudel, Marc; Barsnes, Harald; Berven, Frode et al. (2011). SearchGUI: An open-source graphical user interface for simultaneous OMSSA and X!Tandem searches. (external link)
• Barsnes, Harald; Vaudel, Marc; Colaert, Niklaas et al. (2011). compomics-utilities: an open-source Java library for computational proteomics. (external link)
• Bjørlykke, Yngvild; Berven, Frode; Selheim, Frode (2011). Proteomics in Cerebrospinal fluid: Finding proteins highly enriched in CSF, proteins influenced by the rostro-caudal gradient, and biomarker verification in Multiple Sclerosis. (external link)
• Aasebø, Elise; Berven, Frode; Selheim, Frode (2011). A proteomics study of Cerebrospinal fluid in relation to biomarker discovery and verification in Multiple Sclerosis, with emphasis on the effect of pre-analytical factors. (external link)

2010

• Teunissen, Charlotte; Tumani, HT; Bennett, JL et al. (2010). Short commentary on 'a consensus protocol for the standardization of cerebrospinal fluid collection and biobanking'. (external link)
• Berle, Magnus Foldal; Wester, Knut; Ulvik, Rune Johan et al. (2010). Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults. (external link)
• Teunissen, Charlotte E.; Petzold, Axel; Bennett, Jeffrey L. et al. (2010). A consensus protocol for the standardisation of cerebrospinal fluid collection and biobanking. (external link)
• Kvalheim, Tarja Anniki Rajalahti; Kroksveen, Ann Cathrine; Arneberg, Reidar et al. (2010). A multivariate approach to reveal biomarker signatures for disease classification: application to mass spectral profiles of cerebrospinal fluid from patients with multiple sclerosis. (external link)
• Berven, Frode; Ahmad, Rushdy; Clouser, Karl R. et al. (2010). Optimizing performance of glycopeptide capture for plasma proteomics. (external link)

2009

• Teunissen, Charlotte E.; Petzold, Andreas; Bennett, Jeffrey L. et al. (2009). A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking. (external link)
• Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode et al. (2009). Biomarker discovery in mass spectral profiles by means of selectivity ratio plot. (external link)
• Tumani, Hayrettin; Hartung, Hans-Peter; Hemmer, Bernhard et al. (2009). Cerebrospinal fluid biomarkers in multiple sclerosis. (external link)
• Berven, Frode (2009). Discovery of novel diagnostic biomarker candidates for multiple sclerosis through clinical proteomics. (external link)

2008

• Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode et al. (2008). Biomarker discovery from mass spectral profiles: A combined proteomics and multivariate analysis. (external link)
• Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode et al. (2008). Early diagnosis and biomarker discovery from mass spectral profiles: application to multiple sclerosis. (external link)
• Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)
• Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)
• Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)

2007

• Berven, Frode; Kroksveen, Ann Cathrine; Berle, Magnus Foldal et al. (2007). Pre-analytical influence on the low molecular weight cerebrospinal fluid proteome. (external link)
• Målen, Hiwa; Berven, Frode; Fladmark, Kari Espolin et al. (2007). Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. (external link)
• Arneberg, Reidar; Rajalahti, Tarja; Flikka, Kristian et al. (2007). Pretreatment of mass spectral profiles: Application to proteomic data. (external link)
• Rajalahti, Tarja; Arneberg, Reidar; Flikka, Kristian et al. (2007). Preteatment of Mass Spectral Profiles: Application to proteomic data. (external link)
• Kvalheim, Olav Martin; Rajalahti, Tarja; Arneberg, Reidar et al. (2007). Analysis of Proteomic Profiles. (external link)
• Kvalheim, Olav Martin; Rajalahti, Tarja; Arneberg, Reidar et al. (2007). Target projection and proper data pre-treatment for the analysis of proteomic profiles. (external link)
• Olausson, Sara Karolina; Berven, Frode; Ulvik, Rune Johan (2007). Proteomics applied on cerebrospinal fluid, with focus on methods development and candidate biomarker discovery in multiple sclerosis patients. (external link)

2006

• Berven, Frode; Flikka, Kristian; Berle, Magnus Foldal et al. (2006). Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis. (external link)
• Aukrust, Ingvild; Evensen, Lasse; Hollås, Hanne et al. (2006). Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. (external link)
• Berven, Frode; Karlsen, Odd Andre; Straume, Anne Hege et al. (2006). Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. (external link)
• Wiker, Harald G; Målen, Hiwa; Berven, Frode et al. (2006). Late breaker: Revealing the secreted proteome of Mycobacterium tuberculosis H37Rv. (external link)
• Berven, Frode; Målen, Hiwa; Fladmark, Kari Espolin et al. (2006). Comparing the protein identifications obtained using two-dimensional gel electrophoresis or liquid chromatography mass spectrometry on the secreted proteome of Mycobacterium tuberculosis. (external link)

2005

• Karlsen, Odd Andre; Ramsevik, Linda; Bruseth, Live J. et al. (2005). Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). (external link)
• Berven, Frode; Jensen, Harald B; Lillehaug, Johan (2005). Analysing the outer membrane and subproteome of Methylococcus capsulatus (Bath) using proteomics and bioinformatics. (external link)

2004

• Berven, Frode; Flikka, Kristian; Jensen, Harald B et al. (2004). BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria. (external link)
• Straume, Anne Hege; Jensen, Harald B; Berven, Frode et al. (2004). Methylococcus capsulatus (Bath); Molecular analyses of a surface exposed heteromultimeric protein complex. (external link)

2003

• Berven, Frode; Karlsen, Odd Andre; Murrell, Colin et al. (2003). Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. (external link)
• Karlsen, Odd Andre; Berven, Frode; Stafford, Grasham et al. (2003). The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. (external link)
• Karlsen, Odd Andre; Berven, Frode; Bruseth, Live Janicke et al. (2003). The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium. (external link)
• Berven, Frode; Karlsen, Odd Andre; Fjellbirkeland, Anne et al. (2003). Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath). (external link)
• Berven, Frode; Karlsen, Odd Andre; Murrell, Colin et al. (2003). Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure. (external link)
• Karlsen, Odd Andre; Berven, Frode; Larsen, Øivind et al. (2003). Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath). (external link)
• Karlsen, Odd Andre; Berven, Frode; Larsen, Øivind et al. (2003). Identification of the ORF upstream of MopE in Methylococcus capsulatus. (external link)

2002

• Hordvik, Ivar; Berven, Frode; Solem, Stein Tore et al. (2002). Analysis of two IgM isotypes in Atlantic salmon and brown trout. (external link)
• Berven, Frode; Karlsen, Odd Andre; Jensen, Harald B (2002). Initial proteome studies of Methylococcus capsulatus (Bath). (external link)
• Fjellbirkeland, Anne; Karlsen, Odd Andre; Berven, Frode et al. (2002). Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath). (external link)
• Berven, Frode; Karlsen, Odd Andre; Jensen, Harald B (2002). Initial proteome studies on Methylococcus capsulatus (Bath). (external link)

2001

• Berven, Frode (2001). The establishement and use of 2-dimensional gel electrophoresis in proteome studies of Methylococcus capsulatus(Bath). (external link)

See a complete overview of publications in Cristin.