Research groups
Publications
2022
- Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Wiker, Harald Gotten et al. (2022). A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease. (external link)
- Rosvold, Elin Olaug; Dahl, Christen Peder; Simpson, Melanie Rae et al. (2022). Fastlegevikar uten LIS1 er feil bruk av nye leger. (external link)
- Lie, Anne Helene Kveim; Eriksen, Sara Soraya Aemsangthum; Sharma, Ritika et al. (2022). Klima og bærekraft i helseutdanningene. (external link)
- Skutlaberg, Dag Harald; Wiker, Harald Gotten; Mylvaganam, Haima et al. (2022). Consistent biofilm formation by streptococcus pyogenes emm 1 isolated from patients With necrotizing soft tissue infections. (external link)
2021
- Hoel, Ida Marie; Ali, Iman A Mohammed; Ishtiaq, Sheeba et al. (2021). Immunochemistry-based diagnosis of extrapulmonary tuberculosis: A strategy for large-scale production of mpt64-antibodies for use in the mpt64 antigen detection test. (external link)
- Drengenes, Christine; Eagan, Tomas Mikal; Haaland, Ingvild et al. (2021). Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4. (external link)
- Mohammed, Marwan; Pettersen, Veronika K.; Nerland, Audun Helge et al. (2021). Label-free quantitative proteomic analysis of the oral bacteria Fusobacterium nucleatum and Porphyromonas gingivalis to identify protein features relevant in biofilm formation. (external link)
- Kveim Lie, Anne Helene; Frost Andersen, Lene; Sharma, Ritika et al. (2021). Rapport: Arbeidsgruppe for klima og bærekraft i helseutdanningene.. (external link)
- Nielsen, Rune; Xue, Yaxin; Jonassen, Inge et al. (2021). Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?. (external link)
2020
- Leiten, Elise Orvedal; Nielsen, Rune; Wiker, Harald Gotten et al. (2020). The airway microbiota and exacerbations of COPD. (external link)
- Jouleh, Bahareh; Haaland, Ingvild; Khorsand, Fahimeh et al. (2020). Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD. (external link)
- Riaz, Syeda Mariam; Bjune, Gunnar Aksel; Wiker, Harald G et al. (2020). Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities. (external link)
- Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G (2020). Distinct Metabolic Features of Pathogenic Escherichia coli and Shigella spp. Determined by Label‐Free Quantitative Proteomics. (external link)
- Hoel, Ida Marie; Sviland, Lisbeth; Syre, Heidi et al. (2020). Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting. (external link)
2019
- Machado, Karla C.T.; Fortuin, Suereta; Tomazella, Gisele Guicardi et al. (2019). On the impact of the pangenome and annotation discrepancies while building protein sequence databases for bacteria proteogenomics. (external link)
- Nielsen, Rune; Xue, Yaxin; Jonassen, Inge et al. (2019). Repeated bronchoscopy examination of the airway microbiome. (external link)
- Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne et al. (2019). Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients. (external link)
- Drengenes, Christine; Wiker, Harald G; Kalananthan, Tharmini et al. (2019). Laboratory contamination in airway microbiome studies. (external link)
2018
- Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G (2018). Comparative proteomics of enterotoxigenic escherichia coli reveals differences in surface protein production and similarities in metabolism. (external link)
- Riaz, Syeda Mariam; Sviland, Lisbeth; Wiker, Harald G et al. (2018). Mycobacterial antigen accumulation in foamy macrophages in pulmonary tuberculosis lesions is associated with tissue destruction and disease severity. (external link)
2017
- Hoel, Ida Marie; Sviland, Lisbeth; Wiker, Harald G et al. (2017). Implementation of a new immunohistochemistry-based test for diagnosing extrapulmonary tuberculosis by detection of mycobacterial antigen MPT64. (external link)
- Kittang, Bård Reiakvam; Pettersen, Veronika Kucharova; Oppegaard, Oddvar et al. (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. (external link)
- Tangedal, Solveig; Aanerud, Marianne; Grønseth, Rune et al. (2017). Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. (external link)
- Mohammed, Marwan; Pettersen, Veronika Kucharova; Nerland, Audun Helge et al. (2017). Quantitative proteomic analysis of extracellular matrix extracted from mono- and dual-species biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis. (external link)
- Purohit, Manju; Sviland, Lisbeth; Wiker, Harald G et al. (2017). Rapid and specific diagnosis of extrapulmonary tuberculosis by immunostaining of tissues and aspirates with anti-MPT64. (external link)
- Grønseth, Rune; Drengenes, Christine; Wiker, Harald G et al. (2017). Protected sampling is preferable in bronchoscopic studies of the airway microbiome. (external link)
2015
- Mustafa, Tehmina; Brokstad, Karl Albert; Mfinanga, Sayoki Godfrey M. et al. (2015). Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients. (external link)
- Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G (2015). Improving genome annotation of enterotoxigenic Escherichia coli TW10598 by a label-free quantitative MS/MS approach. (external link)
- Fortuin, Suereta; Tomazella, Gisele Guicardi; Nagaraj, Nagarjuna et al. (2015). Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: Expanding the mycobacterial phosphoproteome catalog. (external link)
2014
- Mustafa, Tehmina; Wiker, Harald G; Harboe, Morten et al. (2014). Mycobacterial antigens disappear from host tissue during latent Mycobacterium tuberculosis infection. (external link)
- Mustafa, Tehmina; Leversen, Nils Anders; Sviland, Lisbet et al. (2014). Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues. (external link)
- Kucharova, Veronika; Wiker, Harald G (2014). Proteogenomics in microbiology: Taking the right turn at the junction of genomics and proteomics. (external link)
- Sivakumaran, Dhanasekaran; Jenum, Synne; Stavrum, Ruth et al. (2014). Effect of non-tuberculous mycobacteria on host biomarkers potentially relevant for tuberculosis management. (external link)
- Grønseth, Rune; Haaland, Ingvild; Wiker, Harald G et al. (2014). The Bergen COPD microbiome study (MicroCOPD): rationale, design, and initial experiences. (external link)
2012
- Leversen, Nils Anders; Wiker, Harald G (2012). Improved signal peptide predictions in mycobacteria?. (external link)
- Leversen, Nils Anders; Sviland, Lisbeth; Wiker, Harald G et al. (2012). Long-term persistence of BCG Pasteur in lungs of C57BL/6 mice following intranasal infection. (external link)
- Kommedal, Øyvind; Simmon, Keith; Karaca, Dilek et al. (2012). Dual-priming oligonucleotides for broad-range amplification of the bacterial 16S rRNA gene directly from human clinical specimens. (external link)
- Tomazella, Gisele Guiqardi; Risberg, Kine; Mylvaganam, Haima et al. (2012). Proteomic analysis of a multi-resistant clinical Escherichia coli isolate of unknown genomic background. (external link)
- Lindemann, Paul Christoffer; Risberg, Kine; Wiker, Harald G et al. (2012). Aminoglycoside resistance in clinical Escherichia coli and Klebsiella pneumoniae isolates from Western Norway. (external link)
- Purohit, Manju; Mustafa, Tehmina; Wiker, Harald G et al. (2012). Rapid diagnosis of tuberculosis in aspirate, effusions, and cerebrospinal fluid by immunocytochemical detection of Mycobacterium tuberculosis complex specific antigen MPT64. (external link)
2011
- Målen, Hiwa; De Souza, Gustavo Antonio; Pathak, Sharad et al. (2011). Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains. (external link)
- Wiker, Harald G; Tomazella, Gisele Guiqardi; De Souza, Gustavo Antonio (2011). A quantitative view on Mycobacterium leprae antigens by proteomics. (external link)
- Fossum, Even; Leversen, Nils Anders; Wiker, Harald G et al. (2011). Targeted Vaccibodies against Mycobacterium tuberculosis. (external link)
- De Souza, Gustavo Antonio; Wiker, Harald G (2011). A proteomic view of mycobacteria. (external link)
- De Souza, Gustavo Antonio; Leversen, Nils Anders; Målen, Hiwa et al. (2011). Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway. (external link)
- Kommedal, Øyvind; Lekang, Katrine; Langeland, Nina et al. (2011). Characterization of polybacterial clinical samples using a set of group-specific broad-range primers targeting the 16S rRNA gene followed by DNA sequencing and RipSeq analysis. (external link)
- De Souza, Gustavo; Arntzen, Magnus Øverlie; Fortuin, Suereta et al. (2011). Proteogenomic analysis of polymorphisms and gene annotation divergences in prokaryotes using a clustered mass spectrometry-friendly database. (external link)
2010
- De Souza, Gustavo; Wiker, Harald G (2010). Proteomic Approaches to Study Immunity in Infection. (external link)
- Leversen, Nils Anders; Mustafa, Tehmina; Wiker, Harald G (2010). Comparison of Immune Response in Mice Infected with M-Bovis BCG Russia and M-Bovis BCG Pasteur. (external link)
- Wiker, Harald G; Mustafa, Tehmina; Bjune, Gunnar et al. (2010). Evidence for waning of latency in a cohort study of tuberculosis. (external link)
- De Souza, Gustavo; Fortuin, Suereta; Aguilar, Diana et al. (2010). Using a Label-free Proteomics Method to Identify Differentially Abundant Proteins in Closely Related Hypo- and Hypervirulent Clinical Mycobacterium tuberculosis Beijing Isolates. (external link)
- Målen, Hiwa; Pathak, Sharad; Søfteland, Tina et al. (2010). Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv. (external link)
- De Souza, Gustavo; Arntzen, Magnus Øverlie; Wiker, Harald G (2010). MSMSpdbb: providing protein databases of closely related organisms to improve proteomic characterization of prokaryotic microbes. (external link)
- Tomazella, Gisele Guiqardi; daSilva, Idalete; Thomé, Carolina H. et al. (2010). Analysis of detergent-insoluble and whole cell lysate fractions of resting neutrophils using high-resolution mass spectrometry. (external link)
- Beyene, Demissew Balcha; Franken, Kees Lumc; Yamuah, Lawrence et al. (2010). Serodiagnosis of tuberculous lymnphadenitis using a combination of antigens. (external link)
2009
- De Souza, Gustavo; Wiker, Harald G (2009). The impact of proteomic advances on bacterial gene annotation. (external link)
- Wiker, Harald G (2009). MPB70 and MPB83 - Major Antigens of Mycobacterium bovis. (external link)
- Beyene, Demissew Balcha; Bergval, Indra; Hailu, Elena et al. (2009). Identification and genotyping of the etiological agent of tuberculous lymphadenitis in Ethiopia. (external link)
- Pathak, Sharad; De Souza, Gustavo; Salte, Tore et al. (2009). HIV Induces both a Down-Regulation of IRAK-4 that Impairs TLR Signalling and an Up-regulation of the Antibiotic Peptide Dermcidin in Monocytic Cells. (external link)
- Olsen, Ingrid; Wiker, Harald G (2009). Diffusion blotting for rapid production of multiple identical imprints from sodium dodecyl sulfate polyacrylamide gel electrophoresis on a solid support. (external link)
- Leversen, Nils Anders; De Souza, Gustavo; Målen, Hiwa et al. (2009). Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods. (external link)
- de Souza, GA; De Souza, Gustavo; Softeland, T et al. (2009). Validating divergent ORF annotation of the Mycobacterium leprae genome through a full translation dataset and peptide identification by tandem mass spectrometry. (external link)
- Kommedal, Øyvind; Kvello, Kristine Ringheim; Skjåstad, Rune et al. (2009). Direct 16S rDNA sequencing from clinical specimens with special focus on poly-bacterial samples and interpretation of mixed DNA chromatograms. (external link)
- Tomazella, Gisele G; da Silva, Idalete; Laure, Helen J et al. (2009). Proteomic analysis of total cellular proteins of human neutrophils. (external link)
- Ellertsen, Linda Kathrine; Storla, Dag G; Diep, Lien M et al. (2009). Allergic sensitisation in tuberculosis patients at the time of diagnosis and following chemotherapy. (external link)
- Mustafa, Tehmina; Wiker, Harald G; Sviland, Lisbet (2009). Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis. (external link)
- Leversen, Nils Anders; De Souza, Gustavo; Målen, Hiwa et al. (2009). Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods. (external link)
- De Souza, Gustavo; Fortuin, Suereta; McEvoy, Christopher R et al. (2009). A label-free method identified differentially abundant proteins in related M.tuberculosis Beijing strains. (external link)
- Totland, Karin; Wiker, Harald G (2009). Kongelig tuberkulose-innblikk. (external link)
- Wiker, Harald G (2009). Fra krysset immunelektroforese til tandem massespektrometri. (external link)
- Wiker, Harald G (2009). Virulensfaktorer og immunitet ved mykobakterieinfeksjoner. (external link)
- Wiker, Harald G (2009). Searching for new vaccine candidates - Proteomics against tuberculosis. (external link)
- Wiker, Harald G; Kommedal, Øyvind; Kvello, Kristine Ringheim (2009). Identifisering av inntil tre ulike bakteriar direkte frå prøvematerialet ved hjelp av direkte 16S rDNA sekvensering. (external link)
2008
- Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)
- Målen, Hiwa; Søfteland, Tina; Wiker, Harald G (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate proteins. (external link)
- Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd et al. (2008). Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis. (external link)
- Beyene, Demissew Balcha; Ashenafi, Senait; Yamuah, Lawrence et al. (2008). Diagnosis of tuberculous lymphadenitis in Ethiopia: correlation with culture, histology and HIV status. (external link)
- Baba, Kamaldeen; Dyrhol-Riise, Anne Ma ; Sviland, Lisbet et al. (2008). Rapid and Specific Diagnosis of Tuberculous Pleuritis With Immunohistochemistry by Detecting Mycobacterium tuberculosis Complex Specific Antigen MPT64 in Patients From a HIV Endemic Area. (external link)
- De Souza, Gustavo Antonio; Målen, Hiwa; Søfteland, Tina et al. (2008). High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example. (external link)
- Leversen, Nils Anders; De Souza, Gustavo Antonio; Målen, Hiwa et al. (2008). Evaluation of signal peptide prediction algoritms using sequence data from proteomic methods. (external link)
- Pathak, Sharad; Leversen, Nils Anders; Wiker, Harald G et al. (2008). Rapid and reliable quantification of mycobacteria inside macrophages in vitro and mice using real-time quantitative PCR. (external link)
- De Souza, Gustavo; Søfteland, Tina; Wiker, Harald G (2008). Proteomic analysis of Mycobacterium leprae. (external link)
- Målen, Hiwa; Søfteland, Tina; Wiker, Harald G (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate proteins. (external link)
- De Souza, Gustavo; Målen, Hiwa; Søfteland, Tina et al. (2008). Validating divergent ORF annotation in M. tuberculosis datasets using a LTQ-Orbitrap. (external link)
- Målen, Hiwa; Søfteland, Tina; Wiker, Harald G (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate. (external link)
- Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)
- Leversen, Nils Anders; De Souza, Gustavo; Målen, Hiwa et al. (2008). Evaluation of signal peptide prediction algorithms using sequence data from proteomic methods. (external link)
- De Souza, Gustavo Antonio; Søfteland, Tina; Wiker, Harald G (2008). Proteomic analysis of Mycobacterium leprae. (external link)
- Pathak, Sharad; Leversen, Nils Anders; Wiker, Harald G et al. (2008). Rapid and reliable quantification of Mycobacteria inside macrophages in vitro and mice mice using real-taime quantitative PCR. (external link)
- Wiker, Harald G; Mustafa, Tehmina; Bjune, Gunnar et al. (2008). Estimating the half-life of latent Mycobacterium tuberculosis infection based on the decline of tuberculosis in Norway. (external link)
- Målen, Hiwa; Søfteland, Tina; Wiker, Harald G (2008). Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate. (external link)
- De Souza, Gustavo; Målen, Hiwa; Søfteland, Tina et al. (2008). Validating divergent ORF annotation in M. tuberculosis datasets using LTQ-Orbitrap. (external link)
- Målen, Hiwa; Berven, Frode; Søfteland, Tina et al. (2008). Membrane- and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. (external link)
- De Souza, Gustavo Antonio; Målen, Hiwa; Søfteland, Tina et al. (2008). Validating divergent ORF annotation in M. tuberculosis datasets using a LTQ-Orbitrap. (external link)
- Wiker, Harald G (2008). TB antigen identification. (external link)
- Wiker, Harald G (2008). En vaksine mot nye epidemier. (external link)
- Wiker, Harald G (2008). Historieløst om kost og leddgikt. (external link)
- Wiker, Harald G (2008). Den norske vaksinen - venn eller fiende?. (external link)
- Wiker, Harald G; Skutlaberg, Dag Harald; Bruarøy, Linda Selstad (2008). Etiologi og resistensmønster ved urinveisinfeksjoner. (external link)
- Wiker, Harald G; Namork, Ellen; Løvik, Martinus et al. (2008). Matallergi - Hvor alvorlig er det? og hva er det man ikke tåler?. (external link)
2007
- Sviland, Lisbet; Mustafa, Tehmina; Purohit, Manju et al. (2007). Immunohistochemistry for the detection of Mycobacterium tuberculosis complex specific antigen (MPT64) improves the diagnosis of extrapulmonary tuberculosis caused by pathogenic mycobacteria. (external link)
- Abebe, F; Holm-Hansen, Carol; Wiker, HG et al. (2007). Progress in serodiagnosis of Mycobacterium tuberculosis infection. (external link)
- Rydjord, Britt; Namork, Ellen; Nygaard, Unni Cecilie et al. (2007). Quantification and characterisation of IgG binding to mould spores by flow cytometry and scanning electron microscopy. (external link)
- Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd et al. (2007). Reduced apoptosis and increased inflammatory cytokines in granulomas caused by tuberculous compared to non-tuberculous mycobacteria: role of MPT64 antigen in apoptosis and immune response. (external link)
- Purohit, Manju Raj; Mustafa, Tehmina; Wiker, Harald G et al. (2007). Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. (external link)
- Målen, Hiwa; Berven, Frode; Fladmark, Kari Espolin et al. (2007). Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. (external link)
- Rydjord, Britt; Eduard, W.; Stensby, Berit Arvesen et al. (2007). Antibody response to long-term and high-dose mould-exposed sawmill workers. (external link)
- Målen, Hiwa; Berven, Frode; Fladmark, Kari et al. (2007). The secreted subproteome and determination of cleavage sites for Signal peptidase I. (external link)
- Purohit, Manju; Mustafa, Tehmina; Wiker, Harald G et al. (2007). Detection of mycobacterium tuberculosis specific antigens by immunohistochemical technique: application for improved diagnosis of abdominal tuberculosis. (external link)
- Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd et al. (2007). Correlation of Mycobacterium tuberculosis antigen MPT64 expression and apoptosis in human tuberculosis lesions. (external link)
- Wiker, Harald G (2007). Hvor lenge varer tuberkuløs latens?. (external link)
- Wiker, Harald G (2007). Innate and specific immune responses to Mycobacterium turberculosis. (external link)
- Wiker, Harald G; Westbrook, Jules (2007). Analysis of exported proteins from Mycobacterium tuberculosis H37Rv. (external link)
- Wiker, Harald G; Fugelsnes, Elin (2007). Vaksiner - Dårligere tuberkulose-vaksine. (external link)
- Wiker, Harald G; Storvik, Anne Grete (2007). Nyttig Vaksine. (external link)
2006
- Wiker, Harald G; Mustafa, Tehmina; Målen, Hiwa et al. (2006). Vaccine approaches to prevent tuberculosis. (external link)
- Wiker, Harald G; Bjune, Gunnar Aksel (2006). Vaksiner mot tuberkulose. (external link)
- Wiker, Harald G (2006). Mykobakterieinfeksjoner. (external link)
- Hetland, G.; Rydjord, Britt; Svenningsen, V. et al. (2006). Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor. (external link)
- Mustafa, Tehmina; Wiker, Harald G; Mfinanga, Sayoki Godfrey M. et al. (2006). Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis. (external link)
- Al-Attiyah, Raja; Madi, Nada M; El-shamy, Abdul Salaam M et al. (2006). Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis. (external link)
- Shrivastava, Rashmi; Das, Dibya Ranjan; Wiker, Harald G et al. (2006). Functional insights from the molecular modelling of a novel two-component system. (external link)
- Wiker, Harald G.; Bjune, Gunnar Aksel (2006). Vaksiner mot tuberkulose. (external link)
- Wiker, Harald G (2006). Kommentarer til MRSA retningslinjene basert på erfaringer fra epidemien i Hordaland. (external link)
- Wiker, Harald G (2006). MRSA - status og framtid. (external link)
- Wiker, Harald G; Målen, Hiwa; Berven, Frode et al. (2006). Late breaker: Revealing the secreted proteome of Mycobacterium tuberculosis H37Rv. (external link)
- Wiker, Harald G (2006). Revealing the secreted proteome of Mycobacterium tuberculosis H37Rv. (external link)
- Wiker, Harald G (2006). Identification of secreted proteins of M. tuberculosis as a basis for vaccine development. (external link)
- Wiker, Harald G (2006). Vaccine research in Norway: Status and future prospects. (external link)
- Wiker, Harald G (2006). Secreted antigens of Mycobacterium tuberculosis H37Rv for novel vaccine design. (external link)
- Wiker, Harald G (2006). Secreted antigens of Mycobacterium tuberculosis H37Rv for novel vaccine design. (external link)
- Wiker, Harald G; Hafstad, Anne (2006). Aldri har flere blitt smittet. (external link)
- Wiker, Harald G (2006). Ny vaksine mot tuberkulose i Bergen. (external link)
- Berven, Frode; Målen, Hiwa; Fladmark, Kari Espolin et al. (2006). Comparing the protein identifications obtained using two-dimensional gel electrophoresis or liquid chromatography mass spectrometry on the secreted proteome of Mycobacterium tuberculosis. (external link)
- Wiker, Harald G; Mustafa, Tehmina; Mustafa, Tehmina et al. (2006). Vaccine approaches to prevent tuberculosis.. (external link)
2005
- Ellertsen, Linda Katrine; Wiker, Harald G; Egeberg, NT et al. (2005). Allergic sensitization in tuberculosis and leprosy patients. (external link)
- Madhurantakam, Chaithanya; Rajakumara, Eerappa; Mazumdar, Pooja Anjali et al. (2005). Crystal Structure of Low Molecular Weight Protein Tyrosine Phosphatase (MPtpA) from Mycobacterium tuberculosis at 1.9 Å resolution. (external link)
- Charlet, Danielle; Mostowy, Serge; Alexander, David et al. (2005). Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK. (external link)
- Rydjord, Britt; Hetland, Geir; Wiker, Harald G (2005). Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor. (external link)
- Mitra, Devrani; Saha, Baisakhee; Das, Debabrata et al. (2005). Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis by homology modeling. (external link)
- Målen, Hiwa; Wiker, Harald G (2005). Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway. (external link)
- Kindingstad, Louise; Fylkesnes, Svein Ivar; Harthug, Stig et al. (2005). Epidemiological analysis of MRSA in two counties in Western Norway. (external link)
- Wiker, Harald G (2005). Molekylær epidemiologi av MRSA utenfor sykehus. (external link)
- Wiker, Harald G (2005). Plenary lecture: The secreted proteomes of Mycobacterium tuberculosis and Mycobacterium leprae. (external link)
- Wiker, Harald G (2005). Får vi snart en ny og bedre vaksine mot tuberkulose?. (external link)
- Wiker, Harald G (2005). Regulation of expression of MPB70 and MPB83 in Mycobacterium bovis BCG substrains. (external link)
- Wiker, Harald G; Gripsrud, Silje (2005). Klistreprotein skaper vaksinekomplikasjoner. (external link)
- Charlet, D; Mostowy, S; Alexander, D et al. (2005). Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK. (external link)
- Målen, Hiwa; Wiker, Harald G (2005). Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway. (external link)
- Wiker, Harald G (2005). Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv. (external link)
- Wiker, Harald G (2005). Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv. (external link)
- Rydjord, B; Wiker, Harald G; Hetland, G (2005). Assay for quantifying mould-specific IgG antibodies in serum by flow cytometry using intact mould spores. (external link)
- Charlet, D; Mostowy, S; Alexander, D et al. (2005). Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK. (external link)
- Kindingstad, L; Fylkesnes, Svein Ivar; Harthug, Stig et al. (2005). Epidemiological analysis of MRSA in two counties in western Norway. (external link)
- Mitra, D; Saha, B; Das, D et al. (2005). Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis by homology modeling. (external link)
2004
- Faeste, CK; Løvik, M; Wiker, Harald G et al. (2004). A Case of Peanut Cross-Allergy to Lupine Flour in a Hot Dog Bread. (external link)
- Harboe, M; Das, AK; Mitra, D et al. (2004). Immunodominant B-cell epitope in the Mce1A mammalian cell entry protein of Mycobacterium tuberculosis cross-reacting with glutathione S-transferase. (external link)
- Wiker, Harald G (2004). Unmatched sequences in public databases - Exemplified by tuberculin-active protein. (external link)
- Instanes, C; Ormstad, Heidi; Rydjord, Britt et al. (2004). Mould extracts increase the allergic response to ovalbumin in mice. (external link)
2003
- Tollefsen, Stig; Pollock, J.M.; Lea, Tor Erling et al. (2003). T- and B-cell epitopes in the secreted Mycobacterium bovis antigen MPB70 in mice. (external link)
- Das, A. K.; Mitra, D.*; Harboe, Morten et al. (2003). Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. (external link)
2002
- Harboe, Morten; Christensen, A.; Ahmed, S. et al. (2002). Cross-reaction between mammalian cell entry (Mce) proteins of Mycobacterium tuberculosis. (external link)
- Harboe, Morten; Whelan, A.O.; Ulvund, Gunni et al. (2002). Generation of antibodies to the signal peptide of the MPT83 lipoprotein of Mycobacterium tuberculosis. (external link)
- Tollefsen, Stig; Tjelle, Torunn Elisabet; Schneider, J. et al. (2002). Improved cellular and humoral immune responses against Mycobacterium tuberculosis antigens after intramuscular DNA immunisation combined with muscle electroporation. (external link)
2001
- Johnson, S.; Brusasca, P.; Lyashcencko, K. et al. (2001). Characterization of the secreted MPT53 antigen of Mycobacterium tuberculosis. (external link)
- Lyashcencko, K.; Wiker, Harald G.; Harboe, Morten et al. (2001). Novel monoclonal antibodies against major antigens of Mycobacterium bovis. (external link)
- Olsen, Ingrid; Wiker, Harald G; Johnson, E et al. (2001). Elevated antibody responses in patients with Crohn’s disease against a 14-kDa secreted protein purified from Mycobacterium avium subsp. paratuberculosis. (external link)
- Olsen, Ingar; Wiker, Harald G.; Johnson, Egil et al. (2001). Elevated antibody responses in patients with Crohn's disease against a 14 kDa secreted protein purified from Mycobacterium avium subspecies paratuberculosis. (external link)
2000
- Olsen, Ingrid; Holstad, Gudmund; Wiker, Harald G et al. (2000). Alkyl hydroperoxide reductases C and D are major antigens constitutively expressed by Mycobacterium avium subsp. paratuberculosi. (external link)
- Olsen, Ingrid; Reitan, Liv Jorun; Wiker, Harald G (2000). Distinct differences in repertoires of low-molecular-mass secreted antigens of Mycobacterium avium complex and Mycobacterium tuberculosis. (external link)
1999
- Wiker, Harald G.; Spierings, E.; Kolkman, M.A.B. et al. (1999). The mammalian cell entry operon 1 (mce1) of Mycobacterium leprae and Mycobacterium tuberculosis. (external link)
- Harboe, Morten; Wiker, Harald G. (1999). Searching for secreted proteins of Mycobacterium leprae. (external link)
- Ahmed, S.; Akbar, P.K.; Wiker, Harald G. et al. (1999). Cloning, expression and immunological reactivity of two mammalian cell entry proteins encoded by the mce1 operon pf Mycobacterium tuberculosis. (external link)
- Harboe, Morten; Christensen, A.; Haile, Y. et al. (1999). Demonstration of expression of six proteins of the mammalian cell entry (mce1) operon of Mycobacterium tuberculosis by anti-peptide antibodies, enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction. (external link)
- Wiker, Harald G.; Michell, S.Ll; Hewinson, R.G. et al. (1999). Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis. (external link)
1998
- Harboe, Morten; Wiker, Harald G.; Ulvund, Gunni et al. (1998). MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. (external link)
- Harboe, Morten; Wiker, Harald G. (1998). Secreted proteins of Mycobacterium leprae. (external link)
- Olsen, Ingrid; Wiker, Harald G. (1998). Diffusion blotting for rapid production of multiple identical imprints from SDS-PAGE on a solid support. (external link)
- Wiker, Harald G.; Lyashcencko, K.; Aksoy, A.M. et al. (1998). Immunochemical characterization of the MPB70/80 and MPB83 proteins of Mycobacterium bovis. (external link)
- Harboe, Morten; Malin, A.S.; Dockrell, H.S. et al. (1998). B-cell epitopes and quantification of the ESAT-6 protein of Mycobacterium tuberculosis. (external link)
- Hetland, Geir; Wiker, Harald G.; Høgåsen, Kolbjørn et al. (1998). Involvement of antilipoarabinomannan antibodies in classical complement activation in tuberculosis. (external link)
- Mustafa, AS; Amoudy, H.A.; Wiker, Harald G. et al. (1998). Comparison of antigen-specific T-cell responses of tuberculosis patients using complex or single antigens of Mycobacterium tuberculosis. (external link)
- Hetland, Geir; Løvik, M.; Wiker, Harald G. (1998). Protective effect of beta-glucan against Mycobacterium bovis BCG infection in Balb/c mice. (external link)
1997
- Manca, C.; Lyashcencko, K.; Wiker, Harald G. et al. (1997). Gene cloning, expression and sequence determination of MPT63, a novel secreted antigen from Mycobacterium tuberculosis. (external link)
- Harboe, Morten; Wiker, Harald G. (1997). Different localization of the homologous MPB70 and MPB83 proteins of Mycobacterium bovis. (external link)
- Manca, C.; Lyashcencko, K.; Wiker, Harald G. et al. (1997). Molecular cloning, purification, and serological characterization of MPT63, a novel antigen secreted by Mycobacterium tuberculosis. (external link)
- Oftung, Fredrik; Wiker, Harald G.; Deggerdal, Arne et al. (1997). A novel mycobacterial antigen relevant to cellular immunity belongs to a family of secreted lipoproteins. (external link)
1996
- Harboe, Morten; Oettinger, T; Wiker, Harald G. et al. (1996). Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. (external link)
- Wiker, Harald G.; Nagai, S; Hewinson, R.G. et al. (1996). Heterogenous expression of the related MPB70 and MPB83 proteins distinguish various substrains of Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv. (external link)
Kompetanse
MD, PhD, Medical speciality in Immunology