James B. Lorens
Position
Professor
Research groups
Publications
Academic article
- Marquez-Palencia, Mauricio; Reza Herrera, Luis; Parida, Pravat Kumar et al. (2024). AXL/WRNIP1 Mediates Replication Stress Response and Promotes Therapy Resistance and Metachronous Metastasis in HER2+ Breast Cancer. (external link)
- Grøndal, Sturla Magnus; Tutusaus, Anna; Boix, Loreto et al. (2024). Dynamic changes in immune cell populations by AXL kinase targeting diminish liver inflammation and fibrosis in experimental MASH. (external link)
- Rayford, Austin James; Gärtner, Fabian; Ramnefjell, Maria Paula et al. (2024). AXL expression reflects tumor-immune cell dynamics impacting outcome in non-small cell lung cancer patients treated with immune checkpoint inhibitor monotherapy. (external link)
- Tenstad, Olav; Christakou, Eleni; Hodneland Nilsson, Linn et al. (2024). In vivo turnover and biodistribution of soluble AXL: implications for biomarker development. (external link)
- Knutsen, Erik; Sajib, Saikat Das; Fiskaa, Tonje et al. (2023). Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes. (external link)
- Liu, Xiaozheng; Rulina, Anastasiia; Choi, Man Hung et al. (2022). C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer. (external link)
- Ekanger, Camilla Tvedt; Zhou, Fan; Bohan, Dana et al. (2022). Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 respiratory virus. (external link)
- Lotsberg, Maria Lie; Røsland, Gro Vatne; Rayford, Austin James et al. (2022). Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. (external link)
- Engelsen, Agnete Svendsen Tenfjord; Lotsberg, Maria Lie; Khouzam, Raefa Abou et al. (2022). Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition. (external link)
- Larrieu, Claire M.; Storevik, Simon Humberto; Guyon, Joris et al. (2022). Refining the Role of Pyruvate Dehydrogenase Kinases in Glioblastoma Development. (external link)
- Li, Huiyu; Liu, Zhida; Liu, Longchao et al. (2022). AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1<sup>+</sup> CD8 T cells. (external link)
- Wogsland, Cara Ellen; Lien, Hilde Eide; Pedersen, Line et al. (2021). High-dimensional immunotyping of tumors grown in obese and non-obese mice. (external link)
- Terry, Stéphane; Dalban, Cécile; Rioux-Leclerq, Nathalie et al. (2021). Association of AXL and PD-L1 Expression with Clinical Outcomes in Patients with Advanced Renal Cell Carcinoma Treated with PD-1 Blockade. (external link)
- Beitzen-Heineke, Antonia; Berenbrok, Nikolaus; Lorens, James Bradley (2021). AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms. (external link)
- Bohan, Dana; Van Ert, Hanora; Ruggio, Natalie et al. (2021). Phosphatidylserine receptors enhance SARS-CoV-2 infection. (external link)
- Chen, Tony Jialiang; Mydel, Piotr Mateusz; Benedyk-Machaczka, Małgorzata et al. (2021). AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model. (external link)
- Dyrstad, Sissel Elisabeth; Lotsberg, Maria Lie; Tan, Tuan Zea et al. (2021). Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with EGFR TKI and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells. (external link)
- Hoel, August; Osman, Tarig; Hoel, Fredrik et al. (2021). Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model. (external link)
- Du, Wenting; Phinney, Natalie Z.; Huang, Huocong et al. (2021). AXL is a key factor for cell plasticity and promotes metastasis in Pancreatic cancer. (external link)
- Bae, Cheong A; Ham, In-Hye; Oh, Hye Jeong et al. (2020). Inhibiting the GAS6/AXL axis suppresses tumor progression by blocking the interaction between cancer-associated fibroblasts and cancer cells in gastric carcinoma. (external link)
- Engelsen, Agnete ; Wnuk-Lipinska, Katarzyna; Bougnaud, Sébastien et al. (2020). AXL is a driver of stemness in normal mammary gland and breast cancer. (external link)
- Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane et al. (2020). AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells. (external link)
- Røsland, Gro Vatne; Dyrstad, Sissel Elisabeth; Tusubira, Deusdedit et al. (2019). Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.. (external link)
- Sharma, Sunita; Xue, Ying; Xing, Zhe et al. (2019). Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect. (external link)
- Landolt, Lea Zoe; Furriol, Jessica; Babickova, Janka et al. (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. (external link)
- Tutusaus, Anna; de Gregorio, Estefanía; Cucarull, Blanca et al. (2019). A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target. (external link)
- Terry, Stéphane; Abdou, Abderemane; Svendsen, Agnete et al. (2019). AXL targeting overcomes human lung cancer cell resistance to NK- And CTL-mediated cytotoxicity. (external link)
- Jokela, Tiina; Svendsen, Agnete; Rybicka, Agata et al. (2018). Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance. (external link)
- Pelissier, Fanny; Schapiro, Dennis; Chang, Hang et al. (2018). High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia. (external link)
- Poirier, Marion; Awale, Mahendra; Roelli, Matthias A. et al. (2018). Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT‐β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2. (external link)
- Bozickovic, Olivera; Skartveit, Linn; Svendsen, Agnete et al. (2018). A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells. (external link)
- Landolt, Lea Zoe; Eikrem, Øystein Solberg; Strauss, Philipp et al. (2017). Clear cell renal cell carcinoma is linked to epithelial-to-mesenchymal transition and to fibrosis. (external link)
- Ertsås, Henriette Christie; Nolan, Garry P.; LaBarge, Mark A. et al. (2017). Microsphere cytometry to interrogate microenvironment-dependent cell signaling. (external link)
- Terry, Stéphane; Buart, Stéphanie; Tan, Tuan Zea et al. (2017). Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity. (external link)
- Haaland, Gry Sandvik; Falk, Ragnhild Sørum; Straume, Oddbjørn et al. (2017). Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years. (external link)
- Ludwig, Kathleen F.; Du, Wenting; Sorelle, Noah B. et al. (2017). Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer. (external link)
- Ellensen, Vegard Skalstad; Abrahamsen, Iren; Lorens, James et al. (2016). Heparin Inhibits Proliferation and Migration of Patient-Derived Vascular Cells Only at Non-physiological Concentrations Due to Antagonistic Pathways. (external link)
- Kirane, Amanda; Ludwig, Kathleen F.; Sorrelle, Noah et al. (2015). Warfarin blocks Gas6-mediated Axl activation required for pancreatic cancer epithelial plasticity and metastasis. (external link)
- Hellesøy, Monica; Lorens, James (2015). Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis. (external link)
- Virtakoivu, Reetta; Mai, Anja; Mattila, Elina et al. (2015). Vimentin-ERK signaling uncouples slug gene regulatory function. (external link)
- Ocal, Ozhan; Pashkov, Victor; Kollipara, Rahul K. et al. (2015). A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics. (external link)
- Hodneland, Linn I.; Pettersen, Ina Katrine Nitschke; Nikolaisen, Julie et al. (2015). A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology. (external link)
- Lorens, James (2015). The immortality two-step. (external link)
- Pelissier, Fanny; Garbe, James C.; Ananthanarayanan, Badriprasad et al. (2014). Age-Related Dysfunction in Mechanotransduction Impairs Differentiation of Human Mammary Epithelial Progenitors. (external link)
- Nikolaisen, Julie; Hodneland, Linn I.; Pettersen, Ina Katrine Nitschke et al. (2014). Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties. (external link)
- Ellensen, Vegard Skalstad; Abrahamsen, Iren; Lorens, James et al. (2014). Auswirkungen von enoxaparin und dalteparin auf die proliferation und migration humaner vaskulärer glatter muskelzellen aus einem patientenkollektiv. (external link)
- Hellesøy, Monica; Blois, Anna; Tiron, Crina Elena et al. (2014). Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis. (external link)
- Kvestad, Hilde; Evensen, Lasse; Lorens, James et al. (2014). In Vitro Characterization of Valproic Acid, ATRA, and Cytarabine Used for Disease-Stabilization in Human Acute Myeloid Leukemia: Antiproliferative Effects of Drugs on Endothelial and Osteoblastic Cells and Altered Release of Angioregulatory Mediators by Endothelial Cells.. (external link)
- Micklem, David Robert; Blø, Magnus; Bergström, Petra et al. (2014). Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets. (external link)
- Pedersen, Torbjørn Østvik; Blois, Anna; Xue, Ying et al. (2014). Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation. (external link)
- Ellensen, Vegard Skalstad; Abrahamsen, Iren; Lorens, James et al. (2014). Effects of enoxaparin and dalteparin on proliferation and migration of patient-derived vascular smooth muscle cells . (external link)
- McCormack, Emmet ; Silden, Elisabeth; West, Richard M. et al. (2013). Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer. (external link)
- Abrahamsen, Iren; Lorens, James (2013). Evaluating extracellular matrix influence on adherent cell signaling by cold trypsin phosphorylation-specific flow cytometry. (external link)
- Evensen, Lasse; Odlo, Kristin; Micklem, David Robert et al. (2013). Contextual compound screening for improved therapeutic discovery. (external link)
- Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe et al. (2013). Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs. (external link)
- Olsen, Jan Roger; Øyan, Anne Margrete; Rostad, Kari et al. (2013). p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. (external link)
- Ben-Batalla, Isabel; Schultze, Alexander; Wroblewski, Mark et al. (2013). Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma. (external link)
- Raddum, Aase Merethe; Evensen, Lasse; Hollås, Hanne et al. (2013). Domains I and IV of annexin A2 affect the formation and integrity of in vitro capillary-like networks. (external link)
- McCormack, Emmet Martin; Haaland, Ingvild; Venås, Gurid et al. (2012). Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia. (external link)
- Oveland, Eystein; Wergeland, Line; Hovland, Randi et al. (2012). Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines. (external link)
- Sapkota, Dipak; Costea, Daniela Elena; Blø, Magnus et al. (2012). S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest. (external link)
- Hatfield, Kimberley Joanne; Evensen, Lasse; Reikvam, Håkon et al. (2012). Soluble mediators released by acute myeloid leukemia cells increase capillary-like networks. (external link)
- Christodoulou, Michael S; Zunino, Franco; Zuco, Valentina et al. (2012). Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation. (external link)
- Pedersen, Torbjørn; Blois, Anna; Xue, Ying et al. (2012). Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells. (external link)
- Radi, Marco; Evensen, Lasse; Dreassi, Elena et al. (2012). A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation. (external link)
- Vuoriluoto, Karoliina; Haugen, Hallvard; Kiviluoto, Santeri et al. (2011). Vimentin regulates EMT induction by Slug and oncogenic H-ras and migration by governing Axl expression in breast cancer. (external link)
- Napolitano, Carmela; Natoni, Alessandro; Santocanale, Corrado et al. (2011). Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation. (external link)
- Wang, Jian; Daphu, Inderjit Kaur; Pedersen, Paal-Henning et al. (2011). A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. (external link)
- Hegen, Anja; Blois, Anna; Tiron, Crina Elena et al. (2011). Efficient in vivo vascularization of tissue-engineering scaffolds. (external link)
- Riva, Elena; Comi, Daniella; Borrelli, Stella et al. (2010). Synthesis and biological evaluation of new camptothecin derivatives obtained by modification of position 20. (external link)
- Napolitano, Carmela; Natoni, Alessandro; Santocanale, Corrado et al. (2010). Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcyclic acid lactone series and biological evaluation. (external link)
- Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill et al. (2010). Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. (external link)
- Evensen, Lasse; Micklem, David Robert; Link, Wolfgang et al. (2010). A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery. (external link)
- Evensen, Lasse; Micklem, David Robert; Blois, Anna et al. (2009). Mural cell associated VEGF is required for organotypic vessel formation. (external link)
- Evensen, Lasse; Micklem, David Robert; Link, W et al. (2009). A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery. (external link)
- Parlati, Francesco; Lee, Susan J.; Aujay, Monette et al. (2009). Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. (external link)
- Blø, Magnus; Micklem, David Robert; Lorens, James (2008). Enhanced gene expression from retroviral vectors. (external link)
- Blø, Magnus; Bogenberger, Jakob M.; Swift, Susan E. et al. (2007). Expanding the spectrum of genetic elements transferable by retroviral vectors. (external link)
- Blø, Magnus; Micklem, David Robert; Lorens, James (2007). Target discovery using retroviruses. (external link)
- McCormack, Emmet Martin; Micklem, David Robert; Pindard, Lars Erik et al. (2007). In vivo optical Imaging of acute myeloid leukemia by green fluorescent protein: Time-domain autofluorescence decoupling, fluorophore quantification, and localization. (external link)
- Bjørndal, Bodil; Myklebust, Line Merethe; Rosendal, Ken Roger et al. (2007). RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells. (external link)
- Stapnes, Camilla I; Døskeland, Anne Paulus; Hatfield, Kimberley Joanne et al. (2007). The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells. (external link)
- Lorens, James; Pearsall, DM; Swift, SE et al. (2004). Stable, stoichiometric delivery of diverse protein functions. (external link)
- Hitoshi, Y; Demo, SD; Masuda, E et al. (2004). Isolation of Genetic Effectors using the Tetracycline-Regulatable System. (external link)
- Oppen-Berntsen, Dag Oskar; Arukwe, Augustine; Yadetie, Fekadu et al. (1999). Salmon eggshell protein expression: A marker for environmental estrogens. (external link)
- Oppen-Berntsen, Dag Oscar; Arukwe, Augustine; Yadetie, Fekadu et al. (1999). Salmon Eggshell Protein Expression: A Marker for Environmental Estrogens.. (external link)
- Amirthalingam, K.; Lorens, James; Sætre, B. O. et al. (1995). Embryonic expression and DNA-binding properties of zebrafish pax-6. (external link)
- Male, Rune; Lorens, James; Nerland, Audun H. et al. (1993). Biotechnology in Aquaculture, with Special Reference to Transgenic Salmon. (external link)
- Lorens, James; Nerland, Audun H.; Aasland, Rein et al. (1993). Expression of growth hormone genes in Atlantic salmon. (external link)
- Male, Rune; Nerland, Audun H.; Lorens, James et al. (1992). The complete nucleotide sequence of the Atlantic salmon growth hormone I gene. (external link)
Masters thesis
- Guttormsen, Maren Sofie Faldalen; Engelsen, Agnete ; Lorens, James et al. (2023). Predictive Biomarkers Beyond Next Generation Sequencing: Functional Testing of Homologous Recombination Repair Deficiency Status in Patient-Derived Tissue Cultures. (external link)
- Rayford, Austin James; Lorens, James; Svendsen, Agnete (2019). The Role of Axl in Cancer and Stem Cell Plasticity: in vivo Lineage Tracing and Imaging Mass Cytometry Analysis. (external link)
- Siraji, Muntequa Ishtiaq; Aarsaether, Niels; Lorens, James (2018). Investigating the role of vitamin K in Axl-mediated melanoma progression and chemotherapeutic resistance. (external link)
- Dhakal, Sushil; Lorens, James; Aarsaether, Niels (2017). Axl Inhibition Enhances Sensitivity of BRAF Mutant Melanoma Cells to Vemurafenib. (external link)
- Kang, Jing; Aarsaether, Niels; Lorens, James (2015). The role of Axl in melanoma metastasis. (external link)
- Dyrstad, Sissel Elisabeth; Tronstad, Karl Johan; Lorens, James (2013). Metabolic reprogramming in Slug and Twist overexpressing MCF10A cells. (external link)
- Lie, Maria Kolnes; Lorens, James (2013). In vitro phenotypic patterning of vascular cells by nano- and micro-design of the matrix substatum. (external link)
- Manandar, Dina; Tronstad, Karl Johan; Lorens, James (2012). A study of mitochondrial function, ROS and signaling in Twist overexpressing cells. (external link)
- Håvardstun, Agathe; Aarsaether, Niels; Lorens, James (2010). Effekten av arakidonsyremetabolitten prostaglandin E2 (PGE2) på humane endotelceller. (external link)
- Hellesøy, Monica; Lorens, James (2008). Assessing Blood Vessel Formation and Maturation in Tissue Engineering Implants -The Role of Akt Kinase. (external link)
- Witsø, Solveig Lund; Lorens, James; Aarsaether, Niels (2008). The disruption of VEGF signalling by the inhibition of delta 5- fatty acid desaturase (dFADS) in HUVECs. (external link)
- Heggland, Ragnhild; Aarsaether, Niels; Lorens, James (2006). Knockdown of p110β subunit of phosphatidylinositol 3-kinase in human umbilical vein endothelial cells with small interfering RNA. (external link)
Academic chapter/article/Conference paper
- Lotsberg, Maria Lie; Chen, Ying Yi; Dhakal, Sushil et al. (2020). Autophagy mediated danger signaling regulates tumor immunosurveillance and may potentiate the effects of anti-cancer immunotherapy through increased adjuvanticity. (external link)
- Davidsen, Kjersti; Haaland, Gry Sandvik; Lie, Maria Kolnes et al. (2017). The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance. (external link)
- Evensen, Lasse; Link, Wolfgang; Lorens, James (2013). Image-based high-throughput screening for inhibitors of angiogenesis. (external link)
- Mora-Blanco, Lorena E.; Lorens, James; LaBarge, Mark A. (2013). The Tumor Microenvironment as a Transient Niche: A Modulator of Epigenetic States and Stem Cell Funct. (external link)
- Gjertsen, Bjørn Tore; Lorens, James (2008). Comprehensive Analysis of Gene Function: RNA interference and Chemical Genomics. (external link)
- Lossius, Ivar; Kryvi, Harald; Lorens, James et al. (1993). Cloning and characterization of growth regulating genes from Atlantic salmon: A strategy for increasing growth rate by microinjection of a modified growth hormone gene into fertilized salmon eggs. (external link)
Academic literature review
- Lotsberg, Maria Lie; Rayford, Austin James; Thiery, Jean Paul et al. (2020). Decoding cancer’s camouflage: epithelial-mesenchymal plasticity in resistance to immune checkpoint blockade. (external link)
- Ferreira, Bibiana I.; Lie, Maria Kolnes; Svendsen, Agnete et al. (2017). Adaptive mechanisms of resistance to anti-neoplastic agents. (external link)
- LaBarge, Mark A.; Parvin, Bahram; Lorens, James (2014). Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics. (external link)
- Zanella, Fabian; Lorens, James; Link, Wolfgang (2010). High content screening: seeing is believing. (external link)
- Evensen, Lasse; Link, Wolfgang; Lorens, James (2010). Image-based high-throughput screening for anti-angiogenic drug discovery. (external link)
- Skaftnesmo, Kai Ove; Prestegarden, Lars; Micklem, David Robert et al. (2007). MicroRNAs in tumorigenesis. (external link)
- Micklem, David Robert; Lorens, James (2007). RNAi screening for therapeutic targets in human malignancies. (external link)
Doctoral dissertation
- Lotsberg, Maria Lie; Lorens, James (2019). The role of AXL and the microenvironment in cancer cell plasticity and therapy responses. A study in non-small cell lung cancer models. (external link)
- Davidsen, Kjersti; Lorens, James (2019). The receptor tyrosine kinase AXL in tumor phenotypic plasticity and acquired resistance to cancer targeted- and immunotherapy. (external link)
- Ertsås, Henriette Christie; Lorens, James; LaBarge, Mark A. et al. (2018). The effects of ageing on microenvironment-contextual epithelial cell signalling . (external link)
- Hinz, Stefan; Lorens, James; Brekken, Rolf A. et al. (2017). Mechanisms of AXL Mediated Cell Plasticity and Drug Resistance . (external link)
- Haaland, Gry Sandvik; Lorens, James (2017). Investigations of the cancer therapeutic and protective effects of warfarin-mediated inhibition of the receptor tyrosine kinase AXL. (external link)
- Pelissier, Fanny; Lorens, James (2016). The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor. (external link)
- Wnuk-Lipinska, Katarzyna; Lorens, James (2015). The role of Axl signaling in phenotypic plasticity in normal and neoplastic epithelial cells. (external link)
- Lorens, James (1993). Molecular studies on the gene structure and expression of Atlantic salmon growth hormone. (dr.scient). (external link)
Abstract
- Schuster, Cornelia; Gausdal, Gro; Gjertsen, Bjørn Tore et al. (2018). Update on the randomised phase Ib/II study of the selective small molecule AXL inhibitor bemcentinib (BGB324) in combination with either dabrafenib/trametinib or pembrolizumab in patients with metastatic melanoma. (external link)
- Ben Batalla, I; Schultze, A; Wroblewski, Mark et al. (2013). Axl, a therapeutic target in AML mediates stroma-induced chemoresistance. (external link)
- Kirane, Amanda R.; Dellinger, Michael T.; Toombs, Jason E. et al. (2013). Warfarin blocks Gas6-mediated Axl activation required for pancreatic tumor EMT and metastasis. (external link)
- Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill et al. (2011). Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. (external link)
- Parlati, F; Lee, S; Aujay, M et al. (2009). CARFILZOMIB: A SELECTIVE INHIBITOR OF THE CHYMOTRYPSIN-LIKE ACTIVITY OF THE CONSTITUTIVE PROTESOME AND IMMUNOPROTEASOME HAS ANTI-TUMOR ACTIVITY ON MULTIPLE MYELOMA, LYMPHOMA AND LEUKEMIA CELLS WITH MINIMAL EFFECTS ON NORMAL CELLS. (external link)
- Gjerdrum, Christine; Tiron, Crina Elena; Haugen, Hallvard et al. (2009). The receptor tyrosine kinase Axl controls breast carcinoma cell invasiveness and tumor formation by regulating E-cadherin. (external link)
- Myklebust, Line Merethe; Bjørndal, Bodil; Rosendal, Ken Roger et al. (2008). The scaffold protein RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells. (external link)
- Parlati, Francesco; Aujay, Monette; Bedringaas, Siv Lise et al. (2007). Anti-tumor activity of immunoproteasome selective inhibitors. (external link)
Letter to the editor
Poster
- Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe et al. (2013). Endothelial Microvascular Networks Influence Gene Expression Profiles in MSCs. (external link)
- Pedersen, Torbjørn; Blois, Anna; Xue, Ying et al. (2012). Osteogenic conditions stimulate microvascular networks – establishing culture conditions for stem cell based reconstruction of bone defects. (external link)
- Xing, Zhe; Xue, Ying; Ibrahim, Salah Osman et al. (2008). Co-culuture of endothelial cells and mesenchymal stem cells on 3D scaffolds. (external link)
- Parlati, F; Aujay, M; Bedringaas, Siv Lise et al. (2007). Anti-Tumor Activity of Immunoproteasome Selective Inhibitors. (external link)
- Silden, Elisabeth; McCormack, Emmet Martin; Micklem, David Robert et al. (2007). Development of a near infrared reporter system for in vivo imaging. (external link)
See a complete overview of publications in Cristin.
A full bibliography is available here.