Hormone Laboratory Research Group (https://www.uib.no/en/rg/hormonelaboratory)

Mohn Nutrition Research Laboratory (funded by the Mohn Foundation)

https://forskning.no/dna-overvekt/fedme-gener-senket-forbrenningen/1676550

https://www.aftenposten.no/sport/sprek/i/dOeRnX/kan-man-faa-bukt-med-fedme-ved-aa-endre-genene-vaare-det-tror-norske-for

https://www.bt.no/sprek/i/8mMqQW/kan-man-faa-bukt-med-fedme-ved-aa-endre-genene-vaare-det-tror-norske-for

- NUTR115

- MEDMET900

- Supervision of masterstudents

Academic article

• Sjøgren, Thea; Bjune, Jan-Inge; Husebye, Eystein Sverre et al. (2024). Regulatory T cells in autoimmune primary adrenal insufficiency. (external link)
• Miftari, Mirushe; Bjune, Jan-Inge; Rong, Chun Jun et al. (2022). Choriolytic and non-choriolytic proteases during hatching of Atlantic Salmon embryos. (external link)
• Gissler, Mark Colin; Anto-Michel, Nathaly; Pennig, Jan et al. (2021). Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. (external link)
• Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, Andre et al. (2021). Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance. (external link)
• Dankel, Simon N; Grytten, Elise; Bjune, Jan-Inge et al. (2020). COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. (external link)
• Bjune, Jan-Inge; Dyer, Laurence; Røsland, Gro Vatne et al. (2019). The homeobox factor Irx3 maintains adipogenic identity. (external link)
• Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita et al. (2018). IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. (external link)
• Madsen, Andre Greger; Bjune, Jan Inge; Bjørkhaug, Lise et al. (2016). The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. (external link)
• Madsen, Andre Greger; Bozickovic, Olivera; Bjune, Jan Inge et al. (2015). Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). (external link)

Academic lecture

• Bjune, Jan-Inge; Dankel, Simon N; Mirza, Shanima Shanu et al. (2022). Genetisk risiko for bukfedme. (external link)
• Bjune, Jan-Inge; Laber, Samantha; Dyer, Laurence et al. (2021). Epigenetic control of adipogenesis by Irx3. (external link)
• Bjune, Jan-Inge (2019). Irx3 er nødvendig for utvikling av fettceller . (external link)
• Bjune, Jan-Inge (2018). IRX5 regulerer APP og mitokondriell respirasjon i fettceller . (external link)
• Bjune, Jan-Inge (2018). Regulation of adipocyte metabolism by Irx3 and Irx5 . (external link)
• Bjune, Jan-Inge (2018). Regulation of adipocyte browning by Irx3 and Irx5 . (external link)
• Bjune, Jan-Inge (2017). Regulation of adipocyte browning by Irx5 . (external link)
• Bjune, Jan-Inge (2016). Transcriptional regulation of adipocyte browning by homeobox factors Irx3 and Irx5. (external link)

Academic literature review

• Bjune, Jan-Inge; Strømland, Pouda Panahandeh; Jersin, Regine Åsen et al. (2022). Metabolic and Epigenetic Regulation by Estrogen in Adipocytes. (external link)
• Visscher, Tommy L.S.; Lakerveld, Jeroen; Olsen, Nanna et al. (2017). Perceived Health Status: Is Obesity Perceived as a Risk Factor and Disease?. (external link)

Popular scientific lecture

• Bjune, Jan-Inge (2018). CRISPR i fettceller: slankekur i sofaen?. (external link)

Poster

• Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita et al. (2018). Irx5 regulates body weight via amyloid precursor protein (App) and mitochondrial respiration in adipocytes. (external link)
• Bjune, Jan-Inge; Haugen, Christine; Gudbrandsen, Oddrun Anita et al. (2018). Irx5 regulates body weight via amyloid precursor protein and mitochondrial respiration in adipocytes. (external link)
• Bjune, Jan-Inge; Madsen, Andre; Bjørkhaug, Lise et al. (2016). PKA downregulates glucose-6phosphatase Expression through RORα and SRC2. (external link)
• Madsen, Andre; Bozickovic, Olivera; Bjune, Jan-Inge et al. (2016). Repression of liver SRC-2 by metformin inhibits glucose, lipid and cholesterol biosynthesis. (external link)

See a complete overview of publications in Cristin.

2022

Bjune JI*, Strømland PP*, Jersin RÅ*, Mellgren G, Dankel SN. Metabolic and Epigenetic Regulation by Estrogen in Adipocytes. Front Endocrinol (Lausanne). 2022 Feb 22;13:828780. doi: 10.3389/fendo.2022.828780. PMID: 35273571; PMCID: PMC8901598. IF 6.055

Miftari MH, Bjune JI, Rong CJ, Nilsen F, Walther BT. Choriolytic and non-choriolytic proteases during hatching of Atlantic Salmon embryos. Comp Biochem Physiol B Biochem Mol Biol. 2022 Oct-Dec;262:110776. IF 2.495.

2021

Gissler MC, Anto-Michel N, Pennig J, Scherrer P, Li X, Marchini T, Pfeiffer K, Härdtner C, Abogunloko T, Mwinyella T, Sol Mitre L, Spiga L, Koentges C, Smolka C, von Elverfeldt D, Hoppe N, Stachon P, Dufner B, Heidt T, Piepenburg S, Hilgendorf I, Bjune JI, Dankel SN, Mellgren G, Seifert G, Eisenhardt SU, Bugger H, von Zur Muhlen C, Bode C, Zirlik A, Wolf D, Willecke F. Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. Arterioscler Thromb Vasc Biol. 2021 Oct;41(10):2563-2574. doi: 10.1161/ATVBAHA.121.316677. Epub 2021 Aug 5. PMID: 34348490. IF 10.514.

Jersin RÅ, Tallapragada DSP, Madsen A, Skartveit L, Fjære E, McCann A, Dyer L, Willems A, Bjune JI, Bjune MS, Våge V, Nielsen HJ, Thorsen HL, Nedrebø BG, Busch C, Steen VM, Blüher M, Jacobson P, Svensson PA, Fernø J, Rydén M, Arner P, Nygård O, Claussnitzer M, Ellingsen S, Madsen L, Sagen JV, Mellgren G, Dankel SN. Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance. Diabetes. 2021 Mar;70(3):680-695. doi: 10.2337/db20-0096. Epub 2021 Jan 6. PMID: 33408126. IF 9.305

2020

Dankel SN, Grytten E, Bjune JI, Nielsen HJ, Dietrich A, Blüher M, Sagen JV, Mellgren G. COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. Sci Rep. 2020 Nov 19;10(1):20164. doi: 10.1038/s41598-020-77406-2. PMID: 33214660; PMCID: PMC7678848. IF 4.997.

Bjune JI, Dyer L, Røsland GV, Tronstad KJ, Njølstad PR, Sagen JV, Dankel SN, Mellgren G. The homeobox factor Irx3 maintains adipogenic identity. Metabolism. 2020 Feb;103:154014. doi: 10.1016/j.metabol.2019.154014. Epub 2019 Nov 18. PMID: 31751577. IF 13.934.

2019

Bjune JI*, Haugen C*, Gudbrandsen O, Nordbø OP, Nielsen HJ, Våge V, NjølstadPR, Sagen JV, Dankel SN and Mellgren G. IRX5 regulates adipocyte amyloidprecursor protein and mitochondrial respiration in obesity. Int J Obes 2019;43:2151-62. IF 5.551.

2017

Visscher TL, Lakerveld J, Olsen N, Küpers L, Ramalho S, Keaver L, Brei C,Bjune JI, Ezquerro S, Yumuk V. Perceived Health Status: Is Obesity Perceived as a Risk Factor and Disease? Obes Facts. 2017;10(1):52-60. doi:10.1159/000457958. Epub 2017 Mar 10. PubMed PMID: 28278496. IF 4.807.

2016

Madsen A*, Bjune JI*, Bjørkhaug L, Mellgren G, Sagen JV. The cAMP-dependentprotein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. Mol Cell Endocrinol. 2016 Jan5;419:92-101. doi: 10.1016/j.mce.2015.10.003. Epub 2015 Oct 9. PubMed PMID:26455881. IF 4.369.

2015

Madsen A, Bozickovic O, Bjune JI, Mellgren G, Sagen JV. Metformin inhibitshepatocellular glucose, lipid and cholesterol biosynthetic pathways bytranscriptionally suppressing steroid receptor coactivator 2 (SRC-2). Sci Rep.2015 Nov 9;5:16430. doi: 10.1038/srep16430. PubMed PMID: 26548416; PubMed Central PMCID: PMC4637908. IF 4.997.

 

*contributed equally

https://www.uib.no/en/rg/hormonelaboratory/66745/obesity-and-diabetes