I am a molecular neuroscientist and clinical psychiatrist with an interest in applying new methods to studies of the brain and human brain diseases.

I am professor of biomedicine and leader of the Neurotargeting Research Group at The University of Bergen. I was director of a multidisciplinary center of excellence (K.G.Jebsen Centre for Neuropsychiatric Disorders) during 2011-2018. I have a 20 % position as senior consultant in clinical psychiatry at Haukeland University Hospital. I am a board-certified specialist of adult psychiatry. From 2002, I have been working as senior consultant in psychiatry at Haukeland University hospital, with a special focus on ADHD and affective disorders. Meeting and treating patients with severe mental disorders have always been an important source of inspiration.

For an overview of recent publications, see Google scholar:

https://scholar.google.com/citations?hl=no&user=8xnQYVQAAAAJ&view_op=list_works&sortby=pubdate

 

My early work included structural and mechanistic studies of key enzymes involved in the synthesis of serotonin and catecholamine transmitters, demonstration of their involvement in human neurological and psychiatric disease and genome wide and targeted genetic studies of bipolar disorder and ADHD.Our research group has characterized the active site structure, reaction mechanism, and regulation by phosphorylation and dephosphorylation of several human enzymes, including tyrosine hydroxylase, tryptophan hydroxylases and pyridoxal dependent decarboxylases, all key to neurotransmitter synthesis.In 2007 I co-founded the International Multi-Centre persistent ADHD Collaboration (IMpACT). We have performed clinical, epidemiological and MRI-imaging/biomarker studies of psychiatric disorders. By extensive international interdisciplinary collaboration, we have discovered of new risk genes and treatment targets across diagnostic boundaries. We have also developed new animal models and shown how old drugs may be repurposed for new indications.   

I have participated in ten EU-funded projects, including 3 ongoing H2020 EU projects. I have mainly worked at universities and hospitals in Norway. I have also been visiting scientist (up to one year at each site) at six other research institutions in Sweden, Scotland, Germany, France, the United States and the Netherlands.

Research awards:

Dr. Haavik has received multiple national and local research awards, including "Søren Falch og øienlæge Sigurd Falchs award for young scientists" in 1997, the “Lundbeck-award” in 2003, the “Innovation and commercialization award” at University of Bergen in 2005 and “Western Norway Health Research prize” in 2016. In Bergen, his research group at Faculty of Medicine has been awarded prizes for “Research group of the year”, “Research paper of the year” and “PhD of the year”. He has been member of the Norwegian Academy of Science and letters from 2018.

 

MED3 Third semester medicine

BMED340 Cellular and molecular neuroscience

2024

• Stefansson, Hreinn; Walters, G. Bragi; Sveinbjornsson, Gardar et al. (2024). Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease. (external link)
• Skuladottir, Astros Th; Stefansdottir, Lilja; Halldorsson, Gisli H. et al. (2024). GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis. (external link)
• Verhoef, Ellen; Allegrini, Andrea G.; Jansen, Philip R. et al. (2024). Genome-Wide Analyses of Vocabulary Size in Infancy and Toddlerhood: Associations With Attention-Deficit/Hyperactivity Disorder, Literacy, and Cognition-Related Traits. (external link)
• Ivarsdottir, Erna V.; Gudmundsson, Julius; Tragante, Vinicius et al. (2024). Gene-based burden tests of rare germline variants identify six cancer susceptibility genes. (external link)
• Ruisch, I. Hyun; Widomska, Joanna; De Witte, Ward et al. (2024). Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases. (external link)
• Instanes, Johanne Telnes; Solberg, Berit Skretting; Kvalvik, Liv Grimstvedt et al. (2024). Organic food consumption during pregnancy and symptoms of neurodevelopmental disorders at 8 years of age in the offspring: the Norwegian Mother, Father and Child Cohort Study (MoBa). (external link)
• MacDonald, Hayley; Kleppe, Rune; Szigetvari, Peter Daniel et al. (2024). The dopamine hypothesis for ADHD: An evaluation of evidence accumulated from human studies and animal models. (external link)
• Jaholkowski, Piotr Pawel; Bahrami, Shahram; Fominykh, Vera et al. (2024). Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development. (external link)
• Baumann, Anne; Papenkordt, Niklas; Robaa, Dina et al. (2024). Aromatic Amino Acid Hydroxylases as Off-Targets of Histone Deacetylase Inhibitors. (external link)
• Kennedy, Eamonn; Liebel, Spencer W.; Lindsey, Hannah M. et al. (2024). Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis. (external link)

See a complete overview of publications in Cristin.