- mari.halle@uib.no
- Visitor address
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Kvinneklinikken Jonas Lies vei 72
5053 Bergen - Postal address
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P.O. Box 7804NO-5020 BergenNorway
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Research groups
Research
I hold a PhD from the University of Bergen on molecular alterations suggesting new treatment strategies in uterine carcinomas. I am currently a researcher in the Bergen Gynecological Cancer Research Group, working on gynecological cancer. My main focus is to characterize targetable molecular alterations driving aggressive uterine carcinoma. Currently, I am working on a study comparing radiomic features from whole tumor segmented magnetic resonance imaging (MRI) scans to genomic profiles. This radiogenomic approach will detect novel prognosticators for disease outcome and may reveal new treatment strategies in cervical cancer.
Publications
Academic article
- Wagner-Larsen, Kari Strøno; Lura, Njål; Gulati, Ankush et al. (2025). MRI delta radiomics during chemoradiotherapy for prognostication in locally advanced cervical cancer. (external link)
- Bellone, Stefania; Jeong, Kyungjo; Halle, Mari Kyllesø et al. (2024). Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix. (external link)
- Halle, Mari Kyllesø; Hodneland, Erlend; Wagner-Larsen, Kari Strøno et al. (2024). Radiomic profiles improve prognostication and reveal targets for therapy in cervical cancer. (external link)
- Halle, Mari Kyllesø; Bozickovic, Olivera; Forsse, David Erik et al. (2024). Clinicopathological and radiological stratification within FIGO 2018 stages improves risk-prediction in cervical cancer. (external link)
- Hodneland, Erlend; Andersen, Erling; Wagner-Larsen, Kari Strøno et al. (2024). Impact of MRI radiomic feature normalization for prognostic modelling in uterine endometrial and cervical cancers. (external link)
- van den Berg, Madeleine Charlotte; Berg, Hege Fredriksen; Stokowy, Tomasz et al. (2024). Expression patterns of mismatch repair proteins in cervical cancer uncover independent prognostic value of MSH-2. (external link)
- Krakstad, Camilla; Berg, Hege Fredriksen; Lindemann, Kristina Yvonne Kathe et al. (2024). Frequency of ERBB2-Low Expression in Endometrial Cancer. (external link)
- Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Fasmer, Kristine Eldevik et al. (2023). MRI-based radiomic signatures for pretreatment prognostication in cervical cancer. (external link)
- Lien, Hilde Eide; Berg, Hege Fredriksen; Halle, Mari Kyllesø et al. (2023). Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease. (external link)
- Eide, Agnes Jørgensen; Halle, Mari Kyllesø; Lura, Njål et al. (2023). Visceral fat percentage for prediction of outcome in uterine cervical cancer. (external link)
- Hodneland, Erlend; Kaliyugarasan, Sathiesh Kumar; Wagner-Larsen, Kari Strøno et al. (2022). Fully Automatic Whole-Volume Tumor Segmentation in Cervical Cancer. (external link)
- Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind et al. (2022). Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer. (external link)
- Sofiyeva, Nigar; Krakstad, Camilla; Halle, Mari Kyllesø et al. (2022). APOBEC3A/B deletion polymorphism and endometrial cancer risk. (external link)
- Lura, Njål Gjærde; Wagner-Larsen, Kari Strøno; Forsse, David Erik et al. (2022). What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer?. (external link)
- Chakravarthy, Ankur; Reddin, Ian; Henderson, Stephen et al. (2022). Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance. (external link)
- Berg, Hege Fredriksen; Engerud, Hilde Renate; Myrvold, Madeleine et al. (2022). Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value. (external link)
- Halle, Mari Kyllesø; Sødal, Marte; Forsse, David Erik et al. (2021). A 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease. (external link)
- Halle, Mari Kyllesø; Munk, Ane Cecilie Dæhli; Engesæter, Birgit Øvstebø et al. (2021). A gene signature identifying CIN3 regression and cervical cancer survival. (external link)
- Øvestad, Irene Tveiterås; Engesæter, Birgit Øvstebø; Halle, Mari Kyllesø et al. (2021). High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling. (external link)
- Høivik, Erling Andre; Hodneland, Erlend; Dybvik, Julie Andrea et al. (2021). A radiogenomics application for prognostic profiling of endometrial cancer. (external link)
- Ruiz, Fiona J.; Sundaresan, Aishwarya; Zhang, Jin et al. (2021). Genomic characterization and therapeutic targeting of HPV undetected cervical carcinomas. (external link)
- Helwa, Reham; Gansmo, Liv Beathe; Bjørnslett, Merete Pauline et al. (2021). Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer. (external link)
- Halle, Mari Kyllesø; Sundaresan, Aishwarya; Zhang, Jianqing et al. (2021). Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinoma.. (external link)
- Engerud, Hilde Renate; Berg, Hege Fredriksen; Myrvold, Madeleine et al. (2020). High degree of heterogeneity of PD-L1 and PD-1 from primary to metastatic endometrial cancer. (external link)
- Berg, Hege Fredriksen; Ju, Zhenlin; Myrvold, Madeleine et al. (2020). Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma. (external link)
- Forsse, David Erik; Berg, Hege Fredriksen; Bozickovic, Olivera et al. (2020). Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer. (external link)
- Holst, Frederik; Werner, Henrica Maria Johanna; Mjøs, Siv et al. (2019). PIK3CA amplification associates with aggressive phenotype but not markers of AKT-mTOR signaling in endometrial carcinoma. (external link)
- Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik et al. (2019). Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling. (external link)
- Strand, Elin; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik et al. (2019). Blood metabolites associate with prognosis in endometrial cancer. (external link)
- Kusonmano, Kanthida; Halle, Mari Kyllesø; Wik, Elisabeth et al. (2018). Identification of highly connected and differentially expressed gene subnetworks in metastasizing endometrial cancer. (external link)
- Bollineni, Vikram Rao; Ytre-Hauge, Sigmund; Gulati, Ankush et al. (2018). The prognostic value of preoperative FDG-PET/CT metabolic parameters in cervical cancer patients. (external link)
- Halle, Mari Kyllesø; Ojesina, Akinyemi I; Engerud, Hilde Renate et al. (2017). Clinicopathologic and molecular markers in cervical carcinoma: a prospective cohort study. (external link)
- Mjøs, Siv; Werner, Henrica Maria Johanna; Birkeland, Even et al. (2017). PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer. (external link)
- Gansmo, Liv Beathe; Bjørnslett, Merete Pauline; Halle, Mari Kyllesø et al. (2017). MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk. (external link)
- Halle, Mari Kyllesø; Tangen, Ingvild Løberg; Berg, Hege Fredriksen et al. (2017). HER2 expression patterns in paired primary and metastatic endometrial cancer lesions. (external link)
- Tangen, Ingvild Løberg; Venereis, Jennifer Taylor; Halle, Mari Kyllesø et al. (2017). Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions. (external link)
- Berg, Anna; Gulati, Ankush; Ytre-Hauge, Sigmund et al. (2017). Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers. (external link)
- Tangen, Ingvild Løberg; Onyango, Therese Bredholt; Kopperud, Reidun Kristin et al. (2016). Androgen receptor as potential therapeutic target in metastatic endometrial cancer. (external link)
- Gibson, William J.; Høivik, Erling Andre; Halle, Mari Kyllesø et al. (2016). The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis. (external link)
- Gansmo, Liv Beathe; Bjørnslett, Merete Pauline; Halle, Mari Kyllesø et al. (2016). The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer. (external link)
- Mauland, Karen Klepsland; Wik, Elisabeth; Høivik, Erling Andre et al. (2016). Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival. (external link)
- Berg, Anna; Fasmer, Kristine Eldevik; Mauland, Karen Klepsland et al. (2016). Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer. (external link)
- Yang, Ji-Yeon; Werner, Henrica Maria Johanna; Li, Jie et al. (2016). Integrative protein-based prognostic model for early-stage endometrioid endometrial cancer. (external link)
- Berg, Anna; Høivik, Erling Andre; Mjøs, Siv et al. (2015). Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients. (external link)
- Krakstad, Camilla; Tangen, Ingvild Løberg; Høivik, Erling Andre et al. (2015). ATAD2 overexpression links to enrichment of B-MYBtranslational signatures and development of aggressive endometrial carcinoma. (external link)
- Earp, Magdalene A; Kelemen, Linda E.; Magliocco, Anthony M. et al. (2014). Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. (external link)
- Ojesina, Akinyemi; Lichtenstein, Lee; Freeman, Samuel S. et al. (2014). Landscape of genomic alterations in cervical carcinomas. (external link)
- Wik, Elisabeth; Trovik, Jone; Kusonmano, Kanthida et al. (2014). Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. (external link)
- Werner, Henrica Maria Johanna; Trovik, Jone; Halle, Mari Kyllesø et al. (2014). Stathmin Protein Level, a Potential Peredictive Marker for Taxane Treatment Response in Endometrial Cancer. (external link)
- Charbonneau, Bridget; Block, MS; Bamlet, WR et al. (2014). Risk of ovarian cancer and the NF-kB pathway: Genetic association with IL1A and TNFSF10. (external link)
- Tangen, Ingvild Løberg; Werner, Henrica Maria Johanna; Berg, Anna et al. (2014). Loss of progesterone receptor links to high proliferation and increases from primary to metastatic endometrial cancer lesions. (external link)
- Halle, Mari Kyllesø; Krakstad, Camilla; Engerud, Hilde Renate Haugen et al. (2014). Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix. (external link)
- Engerud, Hilde Renate Haugen; Tangen, Ingvild Løberg; Berg, Ansgar et al. (2014). High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors. (external link)
- Tangen, Ingvild Løberg; Krakstad, Camilla; Halle, Mari Kyllesø et al. (2014). Switch in FOXA1 status associates with endometrial cancer progression. (external link)
- Høivik, Erling Andre; Kusonmano, Kanthida; Halle, Mari Kyllesø et al. (2014). Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene. (external link)
- Helgeland, Hanna; Sandve, Simen Rød; Torgersen, Jacob et al. (2014). The evolution and functional divergence of the beta-carotene oxygenase gene family in teleost fish-Exemplified by Atlantic salmon. (external link)
- Delahanty, Ryan J.; Xiang, Yong-Bing; Spurdle, Amanda et al. (2013). Polymorphisms in inflammation pathway genes and endometrial cancer risk. (external link)
- Pharoah, Paul D.P.; Halle, Mari Kyllesø; Krakstad, Camilla et al. (2013). GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (external link)
- Permuth-Wey, Jennifer; Lawrenson, K; Shen, HC et al. (2013). Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. (external link)
- Long, Jirong; Zheng, Wei; Xiang, Yong-Bing et al. (2012). Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. (external link)
- Krakstad, Camilla; Birkeland, Even; Seidel, Danila et al. (2012). High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated. (external link)