My main research interest is osmoregulation and acid-base regulation in fish. My professional background is in aquaculture biology and fish physiology where I have extensive knowledge within smolt development and production protocols for salmonids such as Atlantic salmon. My main methods include bioinformatic analysis (both at gene and protein level), enzyme activity assays, gene expression, plasma/serum/urine analysis and catheterization techniques. I also have experience with immunohistochemistry, western blott and cloning.

My PhD thesis focuses on describing and mapping ion transporters in the kidney of Atlantic salmon to better understand the osmoregulatory role of the kidney, which currently is unknown in this species. The goal is to better understand kidney role and function under different environmental conditions and during critical developmental stages of their life cycle. The knowledge gained here will be important to better understand how the kidney is affected in the intensive production protocols currently used in the Norwegian salmon industry. This is especially important due to the reoccurring issues with regulative disorders such as nephrocalsinosis and hemoragic smolt syndrom (HSS) which lead to severe salt precipitation and bleedings in the kidney of salmonids.

Report

• Lal, Pradeep; Oosterkamp, Antonie; Brynildsrud, Mette Espedal et al. (2024). PigghåFRI – Hvordan unngå problemer med pigghå?. (external link)
• Ytrestøyl, Trine; Hjelde, Kirsti; Lal, Pradeep et al. (2023). Betydning av tidspunkt og lengde av vintersignal i RAS for prestasjon i sjø ved utsett av stor smolt. (external link)

Academic article

• Takvam, Marius; Denker, Elsa; Gharbi, Naouel et al. (2024). Differential regulation of magnesium transporters Slc41, Cnnm and Trpm6-7 in the kidney of salmonids may represent evolutionary adaptations to high salinity environments. (external link)
• Takvam, Marius; Denker, Elsa; Gharbi, Naouel et al. (2021). Sulfate homeostasis in Atlantic salmon is associated with differential regulation of salmonid-specific paralogs in gill and kidney. (external link)

Lecture

• Tang, Patrik Anthony; Gilannejad, Neda; Nilsen, Marius et al. (2024). Effect of different inclusion rates of yeast Candida utilis as protein source in hybrid African catfish Clarias gariepinus x Heterobranchus longifilis stress response and lipid metabolism. (external link)
• Takvam, Marius; Sundell, Kristina; Sundh, Henrik et al. (2023). Modifikasjoner av Na+, K+ - ATPase enzymaktivitets protokollen og bruksområder i moderne lakseoppdrett. (external link)
• Takvam, Marius (2023). Nyrefunksjon i laksefisk - biomarkører for bruk i settefiskfasen. (external link)
• Takvam, Marius (2023). Smoltkvalitet og ny metodikk for evaluering av sjøvannstilpasning. (external link)
• Takvam, Marius (2023). Fiskehelse under stort press i norsk oppdrettsnæring - mer målrettet forskning kreves for å løse de største utfordringene. (external link)
• Takvam, Marius (2023). Nyrefunksjon i laksefisk - biomarkører for bruk i settefiskfasen. (external link)
• Takvam, Marius (2023). Smolt Development and kidney function. (external link)
• Takvam, Marius; Denker, Elsa; Gharbi, Naouel et al. (2023). Differential regulation of the magnesium transporter families Slc41, Cnnm and Trpm6-7 in the kidney are associated with adaption to seawater in Atlantic salmon (Salmo salar). (external link)
• Takvam, Marius; Gilannejad, Neda; Lal, Pradeep et al. (2023). Effects of different photoperiod salinity and smolt size on smolt physiology in recirculating aquaculture systems. (external link)

Academic literature review

• Takvam, Marius; Wood, Chris M.; Kryvi, Harald et al. (2023). Role of the kidneys in acid-base regulation and ammonia excretion in freshwater and seawater fish: implications for nephrocalcinosis. (external link)
• Takvam, Marius; Sundell, Kristina; Sundh, Henrik et al. (2023). New wine in old bottles: Modification of the Na+/K+-ATPase enzyme activity assay and its application in salmonid aquaculture. (external link)
• Takvam, Marius; Wood, Chris M.; Kryvi, Harald et al. (2021). Ion transporters and osmoregulation in the kidney of teleost fishes as a function of salinity. (external link)

Poster

• Gilannejad, Neda; Tang, Patrik Anthony; Randulff, Marie Bø et al. (2023). Effect of fishmeal replacement with single cell proteins Candida sp. And Nannochloropsis sp. on rainbow trout Oncorhynchus mykiss osmoregulatory and stress responses. (external link)
• Tang, Patrik Anthony; Gilannejad, Neda; Nilsen, Marius et al. (2023). Effect of different inclusion rates of yeast Candida utilis as protein source in hybrid african catfish Clarias gariepinus x Heterobranchus longifilis, stress response and lipid metabolism. (external link)

See a complete overview of publications in Cristin.