Silje Skrede
Position
Professor, Head of innovation
Affiliation
Publications
Academic article
- Horska, Katerina; Kucera, Jan; Drazanova, Eva et al. (2024). Potent synergistic effects of dulaglutide and food restriction in prevention of olanzapine-induced metabolic adverse effects in a rodent model. (external link)
- Hoprekstad, Gunnhild Eldhuset; Skrede, Silje; Bartz-Johannessen, Christoffer et al. (2024). Association between cytokines and suicidality in patients with psychosis: A multicentre longitudinal analysis. (external link)
- Skrede, Silje; Bogavac-Stanojević, Nataša; Dreesen, Erwin et al. (2024). Therapeutic drug monitoring of monoclonal antibodies in chronic inflammatory diseases: A snapshot of laboratories and applications across Europe. (external link)
- Horska, Katerina; Skrede, Silje; Kucera, Jan et al. (2024). Olanzapine, but not haloperidol, exerts pronounced acute metabolic effects in the methylazoxymethanol rat model. (external link)
- Torgauten, Hilde Marie; Onyango, Therese Bredholt; Ljostveit, Sonja et al. (2024). Hospitalisations and humoral COVID-19 vaccine response in vaccinated rituximab-treated multiple sclerosis patients. (external link)
- Hallin, Erik Ingmar; Serkland, Trond Trætteberg; Bjånes, Tormod Karlsen et al. (2024). High-throughput, low-cost quantification of 11 therapeutic antibodies using caprylic acid precipitation and LC-MS/MS. (external link)
- Hoprekstad, Gunnhild Eldhuset; Kjelby, Eirik; Gjestad, Rolf et al. (2023). Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study. (external link)
- Førde, Jan-Lukas; Herfindal, Lars; Myhr, Kjell-Morten et al. (2023). Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro. (external link)
- Hay, Anne Oldeide; Trones, Roger; Herfindal, Lars et al. (2022). Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. (external link)
- Hallin, Erik Ingmar; Serkland, Trond Trætteberg; Myhr, Kjell-Morten et al. (2022). Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry. (external link)
- Horska, Katerina; Ruda-Kucerova, Jana; Skrede, Silje (2022). GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?. (external link)
- Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø et al. (2021). Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness. (external link)
- Skrede, Silje; Berg, Jon Andsnes; FOSSAN, KJELL OVE et al. (2021). Illicit substances detected through high-resolution MS analysis in urine samples are associated with greater symptom burden in patients with psychosis. (external link)
- Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie et al. (2020). Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial. (external link)
- Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn et al. (2019). Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study. (external link)
- Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even et al. (2019). One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects. (external link)
- Gjerde, Priyanthi Borgen; Dieset, Ingrid; Simonsen, Carmen Elisabeth et al. (2018). Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis. (external link)
- Marti, Andrea Rørvik; Patil, Sudarshan; Mrdalj, Jelena et al. (2017). No escaping the rat race: simulated night shift work alters the time-of-day variation in BMAL1 translational activity in the prefrontal cortex. (external link)
- Ersland, Kari Merete; Skrede, Silje; Stansberg, Christine et al. (2017). Subchronic olanzapine exposure leads to increased expression of myelination-related genes in rat fronto-medial cortex. (external link)
- Skrede, Silje; Gonzalez-Garcia, Ismael; Martins, Luis et al. (2017). Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. (external link)
- Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt et al. (2016). Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial. (external link)
- Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine et al. (2016). Implication of NOTCH1 Gene in Susceptibility to Anxiety and Depression among Sexual Abuse Victims. (external link)
- Marti, Andrea Rørvik; Meerlo, Peter; Grønli, Janne et al. (2016). Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shiftwork: A rat model. (external link)
- Steen, Vidar Martin; Skrede, Silje; Polushina, Tatiana et al. (2016). Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. (external link)
- Grønli, Janne; Meerlo, Peter; Pedersen, Torhild et al. (2016). A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. (external link)
- Fernø, Johan; Ersland, Kari Merete; Duus, Inger Hødnebø et al. (2015). Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. (external link)
- Skrede, Silje; Tvete, Ingunn Fride; Tanum, Lars et al. (2015). Incident users of antipsychotic agents and future use of cholesterol-lowering drugs: An observational, pharmacoepidemiologic study. (external link)
- Reikvam, Håkon; Brenner, Annette; Hagen, Karen Marie et al. (2015). The cytokine-mediated crosstalk between primary human acute myeloid cells and mesenchymal stem cells alters the local cytokine network and the global gene expression profile of the mesenchymal cells. (external link)
- Ersland, Kari Merete; Skrede, Silje; Røst, Therese Halvorsen et al. (2015). Antipsychotic-induced metabolic effects in the female rat: Direct comparison between long-acting injections of risperidone and olanzapine. (external link)
- Skrede, Silje; Martins, Luis; Berge, Rolf Kristian et al. (2014). Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. (external link)
- Reikvam, Håkon; Tamburini, Jerome; Skrede, Silje et al. (2014). Antileukaemic effect of PI3K-mTOR inhibitors in acute myeloid leukaemia-gene expression profiles reveal CDC25B expression as determinate of pharmacological effect. (external link)
- Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt et al. (2014). Blocking blue light during mania - markedly increased regularity of sleep and rapid improvement of symptoms: A case report. (external link)
- Steen, Vidar Martin; Nepal, Chirag; Ersland, Kari Merete et al. (2013). Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1. (external link)
- Skrede, Silje; Steen, Vidar Martin; Fernø, Johan (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (external link)
- Skrede, Silje; Fernø, Johan; Vázquez, Maria Jesús et al. (2012). Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. (external link)
- Jassim, Goran; Skrede, Silje; Vázquez, Maria Jesús et al. (2012). Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. (external link)
- Skrede, Silje; Fernø, Johan; Bjørndal, Bodil et al. (2012). Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. (external link)
- Fernø, Johan; Varela, Luis; Skrede, Silje et al. (2011). Olanzapine-induced hyperphagia and weight gain associate with crexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. (external link)
- Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2011). Lipogenic effects of psychotropic drugs: focus on the SREBP system. (external link)
- Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran et al. (2009). Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. (external link)
- Vik-Mo, Audun Osland; Fernø, Johan; Skrede, Silje et al. (2009). Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. (external link)
- Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2006). Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs. (external link)
- Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland et al. (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. (external link)
- Skrede, Silje; Holmsen, Holm A (2003). Schizofreni og membranpatologi - har antipsykotika en rolle i "membranteorien"?. (external link)
Academic literature review
- Mukherjee, Sayani; Skrede, Silje; Haugstøyl, Martha et al. (2023). Peripheral and central macrophages in obesity. (external link)
- Tyssedal, Malene Kalsnes; Johnsen, Erik; Brønstad, Aurora Margrethe et al. (2023). Dog-assisted interventions for adults diagnosed with schizophrenia and related disorders: a systematic review. (external link)
- Mukherjee, Sayani; Skrede, Silje; Milbank, Edward et al. (2021). Understanding the Effects of Antipsychotics on Appetite Control. (external link)
- Kroken, Rune; Løberg, Else-Marie; Drønen, Tore et al. (2014). A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation. (external link)
Masters thesis
- Skrede, Silje; Sivertsen, Anette; Herfindal, Lars (2023). Zebrafish Larvae as a Model Organism to Study Biotransformation. (external link)
- Sætrang, Maren Sukke; Herfindal, Lars; Skrede, Silje (2022). Electromembrane extraction of immunosuppressants. (external link)
- Hay, Anne Oldeide; Skrede, Silje; Herfindal, Lars (2021). Electromembrane extraction of methotrexate and its metabolites. (external link)
- Herfindal, Lars; Stipic, Martina; Serkland, Trond T. et al. (2020). Drug transport in blood: Lipoproteins as transporters of psychotropic drugs. (external link)
- Skrede, Silje; Bakken, Vibeke Løvås; Ersland, Kari Merete et al. (2018). Gene Expression Changes in Rat Brain Following Long-term Antipsychotic Drug Exposure. (external link)
Poster
- Berg, Jon Andsnes; Skrede, Silje; Hansen, Joakim et al. (2023). "Virtual Pharma" - a digital tool for visualizing pharmacokinetics and pharmacodynamics. (external link)
- Serkland, Trond Trætteberg; Hallin, Erik Ingmar; Myhr, Kjell-Morten et al. (2022). LC-MS/MS quantification of ocrelizumab in the treatment of multiple sclerosis . (external link)
- Serkland, Trond Trætteberg; Hallin, Erik Ingmar; FOSSAN, KJELL OVE et al. (2021). Establishing an LC-MS/MS method as a tool in a TDM approach when treating multiple sclerosis with monoclonal antibodies. (external link)
- Marti, Andrea Rørvik; Skrede, Silje; Mrdalj, Jelena et al. (2018). Extending the photoperiod impacts circadian rhythmicity and gene expression in prefrontal cortex and retina- Impact of exposure to blue-enriched light. . (external link)
- Marti, Andrea Rørvik; waslander, jorrit; Skrede, Silje et al. (2018). Extended photoperiod alters circadian rhythmicity and expression of neuroplasticity markers. The impact of blue-enriched light.. (external link)
- Grønli, Janne; Marti, Andrea Rørvik; waslander, jorrit et al. (2018). Extended photoperiod alters sleep and expression of synaptic plasticity-associated genes. The impact of blue-enriched light.. (external link)
- Kroken, Rune Andreas; Løberg, Else-Marie; Gjestad, Rolf et al. (2017). The influence of 3 weeks of antipsychotic treatment on cell adhesion molecules in drug naive patients with schizophrenia spectrum disorder . (external link)
Academic lecture
- Skrede, Silje (2023). TDM for mAbs - prospects based on progress of analytical methods. (external link)
- Serkland, Trond Trætteberg; Hallin, Erik Ingmar; Myhr, Kjell-Morten et al. (2022). Rituximab in the treatment of multiple sclerosis: A pharmacokinetic-pharmacodynamic model. (external link)
- Marti, Andrea Rørvik; Mrdalj, Jelena; Skrede, Silje et al. (2016). Simulated night work alters clock gene expression in central and peripheral tissue in rats.. (external link)
- Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine et al. (2016). Implication of NOTCH1 Gene in Comorbid Anxiety and Depression Symptoms in a Sample of Sexual Abuse Victims.. (external link)
- Mrdalj, Jelena; Pedersen, Torhild Thue; Marti, Andrea Rørvik et al. (2015). Night work - disturbances in sleep and circadian rhythm parameters. An animal model.. (external link)
Letter to the editor
- Serkland, Trond Trætteberg; Skrede, Silje; Berg, Jon Andsnes (2021). Therapeutic Drug Monitoring vs Standard Therapy during Infliximab Induction in Patients with Chronic Immune-Mediated Inflammatory Diseases. (external link)
- Berg, Jon Andsnes; Schjøtt, Jan; Carstensen, Kjersti et al. (2019). Stability of antidepressants and antipsychotics in gel separator tubes. (external link)
Doctoral dissertation
- Gjerde, Priyanthi Borgen; Steen, Vidar Martin; Melle, Ingrid et al. (2020). Lipid effects during antipsychotic drug treatment and their relevance for clinical outcomes. (external link)
- Skrede, Silje (2012). Developing a rodent model for antipsychotic-induced metabolic adverse effects. (external link)