Short info
Research
I am conducting research under the supervision of Professor Stéphanie Le Hellard within the "Epigenetics and Multiomics" group. In addition, I collaborate with the Polimanti Lab at Yale University, led by Associate Professor Renato Polimanti.
My primary research focus is on gaining a deeper understanding of complex disorders, particularly mental health conditions and women's health, and exploring the connections between the human genome and phenome. By leveraging large-scale datasets from biobanks, I employ a variety of "-omics" approaches, including genomics, epigenomics, metabolomics, and phenomics, to investigate the genetic and environmental factors that contribute to these disorders.
As a medical doctor, my overarching goal is to use these findings to move closer to precision medicine, improving both the diagnosis and treatment of mental health conditions and women's health through more personalized and targeted approaches.
Outreach
I have been actively engaged in science communication through interviews and articles in both Norwegian and international media. I am open to media inquiries to discuss my research and contribute to increased knowledge about genetic epidemiology, mental health, and women’s health.
Examples of media coverage the last year:
- VG: Nye funn om endometriose: Kan være knyttet til skjult årsak
- Women's Agenda: A new study confirms link between trauma and endometriosis – which should change how we diagnose and treat the disease
- Science Norway: Researchers find possible link between endometriosis and childhood trauma
- Adresseavisen (Trd.by): Denne tilstanden kan ha sammenheng med traumer
- Psykologisk.no: Traumer i oppveksten kan øke risikoen for endometriose
- Forskning.no: Forskere finner mulig sammenheng mellom endometriose og traumer i barndommen
- Psykologisk.no: Kan psykologiske traumer gå i arv?
Book Chapters:
- Koller, Dora, Løkhammer, Solveig (2024). The Association of Endometriosis with Mental Health and Disorders. In: Martin, C.R., Preedy, V.R., Patel, V.B., Rajendram, R. (eds) Handbook of the Behavior and Psychology of Disease.Springer, Cham.
- Løkhammer, Solveig (2023). Chapter 9: Epigenetics of Neurodevelopmental Disorders in Epigenetics in Human Disease. Editor: Trygve O. Tollefsbol. Elsevier Academic Press. ISBN: 9780443218118.
Teaching
I have contributed to teaching and student supervision in various roles. I have led colloquiums in genetics for medical students and facilitated practical exams, such as the Formative Objective Structured Clinical Exam (FOSCE) at Stavanger University Hospital. From 2019 to 2022, I served as a Teaching Coordinator/Consultant at the Department of Global Public Health and Primary Care (University of Bergen), where I also mentored students, supervised assignments, and facilitated interprofessional workplace learning through TVEPS.
Publications
2025
- Koller, Dora; Løkhammer, Solveig; Goroshchuk, Oksana et al. (2025). Observational and Genetic Analyses of Traumatic Experiences and Endometriosis. (external link)
- Sandås, Kristoffer; Nery Spindola, Leticia Maria; Løkhammer, Solveig et al. (2025). Using LDpred2 to adapt polygenic risk score techniques for methylation score creation. (external link)
2024
- Friligkou, Eleni; Løkhammer, Solveig Brunstad; Cabrera-Mendoza, Brenda et al. (2024). Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study. (external link)
- Løkhammer, Solveig Brunstad; Koller, Dora; Wendt, Frank R. et al. (2024). Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records. (external link)
- Koller, Dora; Mitjans, Marina; Kouakou, Manuela et al. (2024). Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders. (external link)
- Koller, Dora; Friligkou, Eleni; Stiltner, Brendan et al. (2024). Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders. (external link)
See a complete overview of publications in Cristin.
I have contributed to several peer-reviewed publications in high-impact journals, focusing on genetic epidemiology, mental health, and women's health. My research spans genome-wide association studies, epigenetic and metabolomic analyses, and the integration of biobank data to explore the genetic and environmental factors underlying psychiatric disorders and endometriosis. I have published in journals such as Nature Genetics and JAMA Psychiatry, with studies covering anxiety disorders, endometriosis, environmental factors such as childhood trauma, polygenic risk scores, and the interplay between genetics and mental health conditions.
Projects
- PhD degree project: "Biological and phenomic risk in mental and somatic disorders susceptible of stress and adversity"