Respiratory Medicine to the medical students at the University of Bergen in MED4, MED5, MED6, MED11 and MED12. 

2025

• Rotevatn, Anders Ørskov; Eagan, Tomas Mikal Lind; Tangedal, Solveig et al. (2025). Gut microbiota in chronic obstructive pulmonary disease varies by CT-verified emphysema status. (external link)
• Trollebø, Marte Almenning; Tangvik, Randi Julie; Skeie, Eli et al. (2025). Metabolic profiles and malnutrition in hospitalized adults: A metabolomic cohort study. (external link)

2024

• Trollebø, Marte Almenning; Tangvik, Randi Julie; Skeie, Eli et al. (2024). Malnutrition as a prognostic factor for 2-year mortality in hospitalized patients in Norway: A matched cohort study. (external link)
• Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne et al. (2024). Lower airway microbiota in COPD and healthy controls. (external link)
• Dyrhovden, Ruben; Eagan, Tomas Mikal Lind; Kommedal, Øyvind (2024). Pleural Infection: Contemporary Microbiology Completing the Picture. (external link)
• Mohanty, Biplob Kumar; Eagan, Tomas Mikal Lind; Aarli, Bernt Bøgvald et al. (2024). Trends in Non-Tuberculous Mycobacterial Lung Disease and Treatment Outcomes in a Low-Tuberculosis Prevalence Setting: A Retrospective Analysis. (external link)
• Kommedal, Øyvind; Eagan, Tomas Mikal Lind; Fløtten, Øystein et al. (2024). Microbiological diagnosis of pleural infections: a comparative evaluation of a novel syndromic real-time PCR panel. (external link)

2023

• Bårdsen, Tonje; Røksund, Ola Drange; Eagan, Tomas Mikal Lind et al. (2023). Impaired Lung Function in Extremely Preterm-Born Adults in Their Fourth Decade of Life. (external link)
• Dyrhovden, Ruben; Eagan, Tomas Mikal Lind; Fløtten, Øystein et al. (2023). Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections. (external link)

2022

• Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Wiker, Harald Gotten et al. (2022). A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease. (external link)
• Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune et al. (2022). The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease. (external link)
• Trollebø, Marte Almenning; Skeie, Eli; Revheim, Ingrid et al. (2022). Comparison of nutritional risk screening with NRS2002 and the GLIM diagnostic criteria for malnutrition in hospitalized patients. (external link)
• Svendsen, Christina Due; Kuiper, Karel Kier-Jan; Ostridge, Kristoffer et al. (2022). Factors associated with coronary heart disease in COPD patients and controls. (external link)
• Jonassen, Trygve Müller; Bjorvatn, Bjørn; Saxvig, Ingvild W. et al. (2022). Clinical information predicting severe obstructive sleep apnea: A cross-sectional study of patients waiting for sleep diagnostics. (external link)
• Knudsen, Kristel Svalland; Lehmann, Sverre; Nielsen, Rune et al. (2022). The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis. (external link)
• Carbo, Ellen C.; Sidorov, Igor A.; Rijn-Klink, Anneloes L. van et al. (2022). Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort. (external link)

2021

• Nielsen, Rune; Xue, Yaxin; Jonassen, Inge et al. (2021). Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?. (external link)
• Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Leiten, Elise Orvedal et al. (2021). The pulmonary mycobiome—A study of subjects with and without chronic obstructive pulmonary disease. (external link)
• Wasim, Daanyaal; Alme, Bjørn Arild; Jordal, Stina et al. (2021). Characteristics of 24-hour ambulatory blood pressure monitoring in a COVID-19 survivor. (external link)
• Wåtevik, Marie; Frisk, Bente; Real, Francisco Gomez et al. (2021). CT-defined emphysema in COPD patients and risk for change in desaturation status in 6-min walk test. (external link)
• Drengenes, Christine; Eagan, Tomas Mikal; Haaland, Ingvild et al. (2021). Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4. (external link)

2020

• Husebø, Gunnar; Gabazza, Esteban; D'Alessandro-Gabazza, Corina et al. (2020). Coagulation markers as predictors for clinical events in COPD. (external link)
• Leiten, Elise Orvedal; Eagan, Tomas Mikal; Martinsen, Einar Marius Hjellestad et al. (2020). Complications and discomfort after research bronchoscopy in the MicroCOPD study. (external link)
• Wåtevik, Marie Johanne; Frisk, Bente; Real, Francisco Gomez et al. (2020). One Year Change in 6-Minute Walk Test Outcomes is Associated with COPD Prognosis. (external link)
• Erdal, Marta; Johannessen, Ane; Bakke, Per S. et al. (2020). Incremental costs of COPD exacerbations in GOLD stage 2+ COPD in ever-smokers of a general population. (external link)
• Leiten, Elise Orvedal; Nielsen, Rune; Wiker, Harald Gotten et al. (2020). The airway microbiota and exacerbations of COPD. (external link)
• Durheim, Michael; Hoffmann-Vold, Anna-Maria; Eagan, Tomas Mikal et al. (2020). ILD-specific health-related quality of life in systemic sclerosis-associated ILD compared with IPF. (external link)

2019

• Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne et al. (2019). Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients. (external link)
• Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Leiten, Elise Orvedal et al. (2019). Motivation and response rates in bronchoscopy studies. (external link)
• Husebø, Gunnar; Nielsen, Rune; Hardie, Jon Andrew et al. (2019). Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study. (external link)
• Rijn, Anneloes L. van; Boheemen, Sander van; Sidorov, Igor et al. (2019). The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease. (external link)
• Does, Anne M van der; Heijink, Marieke; Mayboroda, Oleg A. et al. (2019). Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls. (external link)
• Drengenes, Christine; Wiker, Harald G; Kalananthan, Tharmini et al. (2019). Laboratory contamination in airway microbiome studies. (external link)

2018

• Aalstad, Linn Tharaldsen; Hardie, Jon Andrew; Espehaug, Birgitte et al. (2018). Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study. (external link)
• Jouleh, Bahareh; Erdal, Marta; Eagan, Tomas Mikal et al. (2018). Guideline adherence in hospital recruited and population based COPD patients. (external link)
• Aarli, Bernt Bøgvald; Hardie, Jon Andrew; Eagan, Tomas Mikal et al. (2018). Tidal Expiratory Flow Limitation. A new method for evaluating pulmonary function in elderly and patients with Chronic Obstructive Pulmonary Disease. (external link)

2017

• Aardal, Marit Elisabeth; Svendsen, Lene Løvendahl; Lehmann, Sverre et al. (2017). A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability. (external link)
• Conrad, Douglas J.; Bailey, Barbara A.; Hardie, Jon Andrew et al. (2017). Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients. (external link)
• Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L. et al. (2017). The association of tidal EFL with exercise performance, exacerbations, and death in COPD. (external link)
• Husebø, Gunnar; Grønseth, Rune; Lerner, Lorena et al. (2017). Growth differentiation factor-15 is a predictor of important disease outcomes in patients with COPD. (external link)
• Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hardie, Jon Andrew et al. (2017). Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease. (external link)
• Waatevik, Marie; Eagan, Tomas Mikal; Hardie, Jon Andrew et al. (2017). Repeated desaturation in 6 minute walk test increases risk for mortality in COPD patients. (external link)
• Grønseth, Rune; Drengenes, Christine; Wiker, Harald G et al. (2017). Protected sampling is preferable in bronchoscopic studies of the airway microbiome. (external link)
• Tangedal, Solveig; Aanerud, Marianne; Grønseth, Rune et al. (2017). Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. (external link)

2016

• Persson, Louise Jeanette Pauline; Eagan, Tomas Mikal (2016). Vitamin D and antimicrobial peptides in COPD. Results from the Bergen COPD Cohort Study. (external link)
• Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew (2016). Expert opinion of mediastinal lymph node positions from an intrabronchial view. (external link)
• Erdal, Marta; Johannessen, Ane; Eagan, Tomas Mikal et al. (2016). Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients. (external link)
• Storebø, Michael Langballe; Eagan, Tomas Mikal; Eide, Geir Egil et al. (2016). Change in Pulmonary Diffusion Capacity in a General Population Sample over 9 Years. (external link)
• Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Bakke, Per S. et al. (2016). Participation in research bronchoscopy: a literature review. (external link)
• Eagan, Tomas Mikal; Hardie, Jon Andrew; Jul-Larsen, Åsne et al. (2016). Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patients. (external link)
• Jonassen, Trygve Muller; Eagan, Tomas Mikal; Bjorvatn, Bjørn et al. (2016). Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population. (external link)
• Leiten, Elise Orvedal; Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal et al. (2016). Complications and discomfort of bronchoscopy: a systematic review. (external link)
• Aarli, Bernt Bøgvald; Calverley, Peter MA; Soler, Xavier et al. (2016). Longitudinal changes in Peak Oxygen Uptake in Chronic Obstructive Pulmonary Disease (COPD) Patients with Dynamic Hyperinflation and/or Tidal Expiratory Flow Limitation. (external link)
• Husebø, Gunnar; Bakke, Per S.; Grønseth, Rune et al. (2016). Macrophage migration inhibitory factor, a role in COPD. (external link)
• Wåtevik, Marie Johanne; Johannessen, Ane; Real, Francisco Gomez et al. (2016). Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD patients.. (external link)
• Saure, Eirunn Waatevik; Bakke, Per S.; Eagan, Tomas Mikal et al. (2016). Diffusion capacity and CT measures of emphysema and airway wall thickness – relation to arterial oxygen tension in COPD patients.. (external link)

2015

• Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hiemstra, Pieter Sicco et al. (2015). Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD. (external link)
• Frisk, Bente; Hardie, Jon Andrew; Espehaug, Birgitte et al. (2015). Peak oxygen uptake and breathing pattern in COPD patients - a four-year longitudinal study. (external link)
• Aanerud, Marianne; Saure, Eirunn Waatevik; Benet, Marta et al. (2015). Serial measurements of arterial oxygen tension are associated with mortality in COPD. (external link)
• Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L. et al. (2015). Variability of within-breath reactance in COPD patients and its association with dyspnoea. (external link)
• Frisk, Bente; Hardie, Jon Andrew; Espehaug, Birgitte et al. (2015). Peak oxygen uptake and breathing pattern in COPD patients – a four year longitudinal study. (external link)

2014

• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2014). Physical activity and longitudinal change in 6-min walk distance in COPD patients. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2014). Dynamic hyperinflation and respiratory timing during incremental exercise in patients with chronic obstructive pulmonary disease. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2014). Longitudinal change in peak oxygen uptake in COPD patients. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2014). Longitudinal change in peak oxygen uptake in COPD patients. (external link)
• Qvale, Tor Hatlestad; Storstein, Anette; Mazengia, Kibret Yimer et al. (2014). Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease. (external link)
• Grønseth, Rune; Haaland, Ingvild; Wiker, Harald G et al. (2014). The Bergen COPD microbiome study (MicroCOPD): rationale, design, and initial experiences. (external link)
• Husebø, Gunnar Reksten; Bakke, Per S.; Aanerud, Marianne et al. (2014). Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. (external link)
• Olfert, I. Mark; Malek, Moh H.; Eagan, Tomas Mikal et al. (2014). Inflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients 'on' or 'off' augmentation therapy. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2014). Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients. (external link)
• Aarli, Bernt Bøgvald; Calverley, PM; Eagan, Tomas Mikal et al. (2014). Mortality In COPD Patients With Increased Intrabreath Reactance. (external link)
• Aarli, Bernt Bøgvald; Calverley, Peter MA; Eagan, Tomas Mikal et al. (2014). Flow limitation during resting breathing is associated with reduced exercise capability in COPD.. (external link)
• Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy et al. (2014). Predictors for PaO2 and hypoxemic respiratory failure in COPD-A three-year follow-up. (external link)
• Tangedal, Solveig; Aanerud, Marianne; Persson, Louise Jeanette Pauline et al. (2014). Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients. (external link)
• Erdal, Marta; Johannessen, Ane; Askildsen, Jan Erik et al. (2014). Productivity losses in chronic obstructive pulmonary disease: a population-based survey.. (external link)

2013

• Aarli, Bernt Bøgvald; Eagan, Tomas Mikal; Ellingsen, Ivar et al. (2013). Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly. (external link)
• Johannessen, Ane; Nilsen, Roy Miodini; Storebø, Michael Langballe et al. (2013). Comparison of 2011 and 2007 global initiative for chronic obstructive lung disease guidelines for predicting mortality and hospitalization. (external link)
• Hynninen, Kia Minna; Pallesen, Ståle; Hardie, Jon Andrew et al. (2013). Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2013). Slope and curvature of the relationship between ventilation and tidal volume in COPD patients. (external link)
• Aarli, Bernt Bøgvald; Calverley, PM; Eagan, Tomas Mikal et al. (2013). Can intra-breath variations of reactance predict dyspnea?. (external link)
• Aanerud, Marianne; Braut, Harald; Wentzel-Larsen, Tore et al. (2013). Non-response in telephone surveys of COPD patients does not introduce bias. (external link)

2012

• Gjerde, Bjarte; Bakke, Per S.; Ueland, Thor et al. (2012). The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway. (external link)
• Bakke, Per S.; Rönmark, Eva; Eagan, Tomas Mikal et al. (2012). Recommendations for epidemiological studies on COPD. (external link)
• Eagan, Tomas Mikal; Gabazza, Esteban C.; D'Alessandro-Gabazza, Corina et al. (2012). TNF-alpha is associated with loss of lean body mass only in already cachectic COPD patients. (external link)
• Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew et al. (2012). Predictors for longitudinal change in 6-Minute Walk Distance in COPD patients. (external link)
• Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy et al. (2012). Explained variance for blood gases in a population with COPD. (external link)
• Aarli, Bernt Bøgvald; Calverley, PM; Eagan, Tomas Mikal et al. (2012). Exacebation history in COPD patients with and without expiratory flow limitation (EFL).. (external link)
• Johannessen, Ane; Bakke, Per S.; Hardie, Jon Andrew et al. (2012). Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults. (external link)
• Waatevik, Marie Johanne; Johannessen, Ane; Hardie, Jon Andrew et al. (2012). Different COPD disease characteristics are related to different outcomes in the 6-minute walk test. (external link)
• Aarli, Bernt Bøgvald; Calverley, PM; Eagan, Tomas Mikal et al. (2012). Longitudinal Variability Of Expiratory Flow Limitation (EFL) In COPD Patients And Healthy Smokers Detected Non-invasively By Impulse Oscillometry. (external link)
• Persson, Louise; Aanerud, Marianne; Hiemstra, Pieter Sicco et al. (2012). Chronic obstructive pulmonary disease is associated with low levels of vitamin D. (external link)

2011

• Fasmer, Ole Bernt; Riise, Trond; Eagan, Tomas Mikal et al. (2011). Comorbidity of Asthma With ADHD. (external link)
• Waatevik, Marie; Bjordal, Jan Magnus; Eagan, Tomas Mikal (2011). 6 minutts gangtest hos KOLS-pasienter. (external link)
• Bakke, Per S.; Rönmark, Eva; Eagan, Tomas Mikal et al. (2011). Recommendations for epidemiological studies on COPD. (external link)
• Roth, Kjetil; Eagan, Tomas Mikal; Andreassen, Alf Henrik et al. (2011). A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions. (external link)
• Fasmer, Ole Bernt; Halmøy, Anne; Eagan, Tomas Mikal et al. (2011). Adult attention deficit hyperactivity disorder is associated with asthma. (external link)
• Edvardsen, Anne; Akerø, Aina; Hardie, Jon Andrew et al. (2011). High prevalence of respiratory symptoms during air travel in patients with COPD. (external link)
• Aarli, Bernt Bøgvald; Calverley, PM; Eagan, Tomas Mikal et al. (2011). Expiratory flow limitation (EFL) detected non-invasively as a phenotypic characteristic of COPD. (external link)

2010

• Eagan, Tomas Mikal Lind; Ueland, Thor; Wagner, Peter D. et al. (2010). Systemic inflammatory markers in chronic obstructive pulmonary disease – results from the Bergen COPD Cohort Study. (external link)
• Eagan, Tomas Mikal Lind; Damås, Jan Kristian; Ueland, Thor et al. (2010). Neutrophil Gelatinase-Associated Lipocalin A Biomarker in COPD. (external link)
• Grydeland, Thomas; Dirksen, Asger; Coxson, Harvey O. et al. (2010). Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. (external link)
• Voll-Aanerud, Marianne; Eagan, Tomas Mikal Lind; Plana, Estel et al. (2010). Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey. (external link)
• Aarli, Bernt Bøgvald; Calverley, Peter; Eagan, Tomas Mikal et al. (2010). Reference values for resistance and reactance measures from Impuls Oscillometry in healthy elderly. (external link)
• Johannessen, Ane; Eagan, Tomas Mikal Lind; Omenaas, Ernst et al. (2010). Socioeconomic risk factors for lung function decline in a general population. (external link)
• Edvardsen, Anne; Akerø, Aina; Eagan, Tomas Mikal Lind et al. (2010). In-flight respiratory symptoms and pre-flight characteristics in patients with COPD. (external link)
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S. et al. (2010). Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. (external link)
• Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew (2010). Significance of endobronchial lesion appearance in the diagnostic value of different endoscopic techniques Response. (external link)
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Ueland, Thor et al. (2010). Body composition and plasma levels of inflammatory biomarkers in COPD. (external link)
• Edvardsen, Anne; Akerø, Aina; Eagan, Tomas Mikal Lind et al. (2010). Air travel habits in patients with COPD. (external link)

2009

• Skorge, Trude Duelien; Eagan, Tomas Mikal Lind; Eide, Geir Egil et al. (2009). Occupational exposure and incidence of respiratory disorders in a general population. (external link)
• Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik et al. (2009). Cost minimization analysis for combinations of sampling techniques in bronchoscopy of endobronchial lesions. (external link)
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S. et al. (2009). Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. (external link)
• Grydeland, Thomas; Dirksen, Asger; Coxson, Harvey O. et al. (2009). Quantitative CT Measures of Emphysema and Airway Wall Thickness Are Related to Respiratory Symptoms. (external link)
• Aarli, Bernt Bøgvald; Jensen, Robert L.; Eagan, Tomas Mikal et al. (2009). Within-day repeatability and signal to noise ratio for IOS parameters and FEV1 in smokers with and without COPD. (external link)

2008

• Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik et al. (2008). Predictors of diagnostic yield in bronchoscopy: a retrospective cohort study comparing different combinations of sampling techniques. (external link)
• Voll-Aanerud, Marianne; Eagan, Tomas Mikal Lind; Wentzel-Larsen, Tore et al. (2008). Respiratory symptoms, COPD severity, and health related quality of life in a general population sample. (external link)

2007

• Aanerud, Marianne; Eagan, Tomas Mikal Lind; Wentzel-Larsen, Tore et al. (2007). Changes in Respiratory Symptoms and Health-Related Quality of Life. (external link)
• Skorge, Trude Duelien; Eagan, Tomas Mikal Lind; Eide, Geir Egil et al. (2007). JEM-based occupational exposure assessment and incidence of respiratory disorders in a community sample. (external link)

See a complete overview of publications in Cristin.

 

 

The Bergen COPD Microbiome Study (MicroCOPD)

The study aims to characterize the airways microbiome in patients with COPD, compared with healthy adults.

Secondary motives are to assess different bronchoscopic sampling techniques, to compare the microbiome within the lungs (upper versus lower airways, left versus right lung), the stability of the microbiome, and to study the impact of tobacco smoking and composition of the lower airways microbiome on development of COPD.

The pilot study was performed spring of 2012, data collection was performed 213-2015.16Sr DNA sequencing was performed in-house on the Illumina MiSeq platform. Several research papers have been published from this study, and already three bright PhD students (Einar Marius Martinsen, Christine Drengenes and Elise Leiten) have finalized their PhD projects with data from this study. Several more are underway.

The lung microbiome in interstitial lung disease Study (MicroILD)

This is an extension of the MicroCOPD study, with the aim to characterize the airways microbiome in patients undergoing evaluation for interstitial lung diseases. Data collection was performed 2014-2016, and 70 patients with ILDs were included, and papers on IPF and sarcoidosis have been published.

The lung microbiome in lung cancer study (MicroLC)

The final extension of the MicroCOPD study is per August 2023 in its pilot phase. We aim to examine how the pulmonary and gut microbiome influences risk of lung cancer, influence on treatment response and risk of treatment-related side effects.

The Bergen GeneCOPD follow-up study (GenKOLS follow-up)

The first Bergen GeneCOPD study was performed in 2002/04, where 500 COPD patients and healthy controls were assessed with a CT scan, lung function testing and clinical data, and gene wide association studies were performed. In 2014 the follow-up started, aiming to include 250 patients and 400 controls. The primary study question is the assessment of longitudinal change in COPD assessed by CT thorax, secondary motive is to assess risk factors for comorbid coronary heart disease. 

The Bergen COPD Cohort Study (BergenCOPD)

The study started in 2006 and ended in 2014. More than 400 COPD patients and 300 healthy controls were included, and most were attempted followed until the end of 2014, with annual clinical examinations.

The main research question was to search for predictors of later advers outcomes such as mortality, exacerbation frequency, development of cachexia and lung function decline. Almost 40 research papers are published from this study, and data from this study have been part of a number of PhD theses (Louise Persson, Eirunn Waatevik, Bernt Aarli, Bente Frisk, Marie Waatevik, Gunnar Husebø, Solveig Tangedal)