Nyreforskningsgruppen er et åpent forum for klinisk og translasjonell nyreforskning i Bergen. Nyreforskningsgruppen har tradisjonelt kombinert human- og dyremodeller for å studere sykdomsmekanismer, med avanserte molekylære analyser av nyrebiopsier og digital patologi. I tillegg gjennomføres både epidemiologiske studier av risikofaktorer og sykdomsutvikling ved kronisk nyresykdom i tillegg til flere pågående kliniske studier.

2025

• Chen, Tony Jialiang; Skandalou, Eleni; Fritz-Wallace, Katarina et al. (2025). Serum proteome analysis detects early molecular signatures of disease progression in IgA nephropathy. (ekstern lenke)
• Pettersen, Simen Femanger; Skandalou, Eleni; Palmer, Jessica Furriol et al. (2025). Reconstruction of Single-Cell Spatial Transcriptomes in Archival Kidney Biopsies. (ekstern lenke)
• Nordbø, Ole Petter; Eikrem, Øystein Solberg; Kalra, Philip A. et al. (2025). Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression. (ekstern lenke)
• Øvrehus, Marius Altern; Langlo, Knut Asbjørn Rise; Leh, Sabine et al. (2025). Correction to: Norwegian kidney biopsy biobank (NorKiBB): organization, baseline characteristics, and generalizability of a low-cost national biobank (BMC Nephrology, (2025), 26, 1, (76), 10.1186/s12882-025-04007-4). (ekstern lenke)
• Øvrehus, Marius Altern; Langlo, Knut Asbjørn Rise; Leh, Sabine et al. (2025). Norwegian kidney biopsy biobank (NorKiBB): organization, baseline characteristics, and generalizability of a low-cost national biobank. (ekstern lenke)
• Rivedal, Mariell Lossius; Nordbø, Ole Petter; Haaskjold, Yngvar Lunde et al. (2025). Lifetime progression of IgA nephropathy: a retrospective cohort study with extended long-term follow-up. (ekstern lenke)

2024

• Rivedal, Mariell Lossius; Haaskjold, Yngvar Lunde; Eikrem, Øystein Solberg et al. (2024). Use of corticosteroids in Norwegian patients with immunoglobulin a nephropathy progressing to end-stage kidney disease: a retrospective cohort study. (ekstern lenke)

2023

• Eikrem, Øystein Solberg; Lillefosse, Bjørnar Sandnes; Delaleu, Nicolas et al. (2023). Network-Based Assessment of Minimal Change Disease Identifies Glomerular Response to IL-7 and IL-12 Pathways Activation as Innovative Treatment Target. (ekstern lenke)
• Nordbø, Ole Petter; Landolt, Lea Zoe; Eikrem, Øystein Solberg et al. (2023). Transcriptomic analysis reveals partial epithelial–mesenchymal transition and inflammation as common pathogenic mechanisms in hypertensive nephrosclerosis and Type 2 diabetic nephropathy. (ekstern lenke)
• Rivedal, Mariell Lossius; Mikkelsen, Håvard; Marti, Hans Peter et al. (2023). Glomerular transcriptomics predicts long term outcome and identifies therapeutic strategies for patients with assumed benign IgA nephropathy. (ekstern lenke)
• Elsaid, Hassan Osman Alhassan; Rivedal, Mariell Lossius; Skandalou, Eleni et al. (2023). Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla ^−/− zebrafish model of Fabry disease. (ekstern lenke)
• Delaleu, Nicolas; Marti, Hans Peter; Strauss, Philipp et al. (2023). Systems analyses of the Fabry kidney transcriptome and its response to enzyme replacement therapy identified and cross-validated enzyme replacement therapy-resistant targets amenable to drug repurposing. (ekstern lenke)
• Sekulic, Miroslav; Batal, Ibrahim; Kudose, Satoru et al. (2023). Kidney Dysfunction and Pathology in the Setting of Hemophagocytic Lymphohistiocytosis. (ekstern lenke)
• Braun, Fabian; Abed, Ahmed; Sellung, Dominik et al. (2023). Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy. (ekstern lenke)
• Strauss, Philipp; Eikrem, Øystein Solberg; Marti, Hans Peter et al. (2023). From archival tissues to systems biology: Using transcriptomics to investigate the progression of kidney disease. (ekstern lenke)

2022

• Mikkelsen, Håvard; Vikse, Bjørn Egil; Eikrem, Øystein Solberg et al. (2022). Glomerular proteomic profiling of kidney biopsies with hypertensive nephropathy reveals a signature of disease progression. (ekstern lenke)
• Elsaid, Hassan Osman Alhassan; Tjeldnes, Håkon; Rivedal, Mariell Lossius et al. (2022). Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca²⁺ Signaling Similar to Fabry Disease. (ekstern lenke)
• Strauss, Philipp; Rivedal, Mariell; Scherer, Andreas et al. (2022). A multiomics disease progression signature of low-risk ccRCC. (ekstern lenke)

2021

• Braun, Fabian; Abed, Ahmed; Woidy, Mathias et al. (2021). Synuclein Alpha Accumulation Drives Lysosomal Dysfunction in Fabry Podocytopathy. (ekstern lenke)
• Nakken, Sigrid; Eikrem, Øystein Solberg; Marti, Hans Peter et al. (2021). AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease. (ekstern lenke)
• Eikrem, Øystein Solberg; Kotopoulis, Spiros; Popa, Mihaela-Lucia et al. (2021). Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys. (ekstern lenke)

2020

• Eikrem, Øystein Solberg; Delaleu, Nicolas; Strauss, Philipp et al. (2020). Systems Analyses of Renal Fabry Transcriptome and Response to Enzyme Replacement Therapy (ERT) Identifies a Cross-Validated and Druggable ERT-Resistant Module. (ekstern lenke)
• Mazzawi, Tarek; Eikrem, Øystein Solberg; Lied, Gülen Arslan et al. (2020). Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation. (ekstern lenke)

2019

• Eikrem, Øystein Solberg; Marti, Hans-Peter (2019). New methods clear the dust off old biopsies. RNA sequencing of FFPE kidney biopsies. (ekstern lenke)
• Strauss, Philipp; Eikrem, Øystein Solberg; Tøndel, Camilla et al. (2019). Fabry Nephropathy: First mRNA-seq Findings from Kidney Biopsies Before and After Enzyme Replacement Therapy. (ekstern lenke)
• Koch, Even; Finne, Kenneth; Eikrem, Øystein Solberg et al. (2019). Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms. (ekstern lenke)
• Landolt, Lea Zoe; Furriol, Jessica; Babickova, Janka et al. (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. (ekstern lenke)

2018

• Eikrem, Øystein Solberg; Walther, Tedd Christian; Flatberg, Arnar et al. (2018). Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys. (ekstern lenke)
• Strauss, Philipp; Marti, Hans-Peter; Beisland, Christian et al. (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma. (ekstern lenke)
• Koch, Even Evjen; Eikrem, Øystein Solberg; Flatberg, Arnar et al. (2018). Fine needle aspirates of kidneys are usable for RNA sequencing like regular core biopsies. (ekstern lenke)
• Strauss, Philipp; Koch, Even Evjen; Marti, Hans-Peter et al. (2018). Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasability of miRNA-sequencing for disease exploration and biomarker development from biopsies with clear cell renal cell carcinoma. (ekstern lenke)
• Eikrem, Øystein Solberg; Koch, Even Evjen; Knoop, Thomas et al. (2018). Primary Membranous Nephropathy: Glomerular RNA Sequencing from Archival Kidney Biopsies. (ekstern lenke)
• Eikrem, Øystein Solberg; Marti, Hans-Peter (2018). Klarcellet nyrekarsinom er knyttet til epitelial-til- mesenkymal overgang (EMT) og til fibrose. (ekstern lenke)
• Eikrem, Øystein Solberg; Strauss, Philipp; Sekulic, Miroslav et al. (2018). Fabry nephropathy: Transcriptome sequencing of microdissected renal compartments from archival kidney biopsies at baseline, and after 5 & 10 years of enzyme replacement therapy. (ekstern lenke)

2017

• Svarstad, Einar; Leh, Sabine Maria; Skrunes, Rannveig et al. (2017). Bedside stereomicroscopy of Fabry kidney biopsies: An easily available method for diagnosis and assessment of sphingolipid deposits. (ekstern lenke)
• Eikrem, Øystein Solberg; Skrunes, Rannveig; Tøndel, Camilla et al. (2017). Pathomechanisms of renal Fabry disease. (ekstern lenke)
• Landolt, Lea Zoe; Eikrem, Øystein Solberg; Strauss, Philipp et al. (2017). Clear cell renal cell carcinoma is linked to epithelial-to-mesenchymal transition and to fibrosis. (ekstern lenke)

2016

• Eikrem, Øystein Solberg; Strauss, Philipp; Beisland, Christian et al. (2016). Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. (ekstern lenke)
• Landolt, Lea Zoe; Marti, Hans-Peter; Beisland, Christian et al. (2016). RNA extraction for RNA sequencing of archival renal tissues. (ekstern lenke)
• Eikrem, Øystein Solberg; Beisland, Christian; Hjelle, Karin Margrethe et al. (2016). Transcriptome sequencing (RNAseq) enables utilization of formalin-fixed, paraffin-embedded biopsies with clear cell renal cell carcinoma for exploration of disease biology and biomarker development. (ekstern lenke)
• Landolt, Lea Zoe; Strauss, Philipp; Marti, Hans-Peter et al. (2016). Next generation sequencing: A tool for this generation of nephrologists. (ekstern lenke)
• Eikrem, Øystein Solberg; Scherer, Andreas; Landolt, Lea Zoe et al. (2016). Development and Confirmation of Gene Classifiers of Human Clear Cell Renal Cell Carcinoma Using Next-Generation Sequencing [Abstract].. (ekstern lenke)
• Landolt, Lea Zoe; Eikrem, Øystein Solberg; Gausdal, Gro et al. (2016). Detection and Validation of Epithelial-to-Mesenchymal Transition(EMT) with Increased Expression of Axl and MMP-14 in Renal Cell Carcinoma. (ekstern lenke)

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