Postdoctoral fellow in the Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway

The main focus of the Postdoc project is to study the T and B-cell immunity after influenza vaccination and/or infection in humans.

01.09.2008 - 30.06.2013

Ph.D. 

University of Chinese Academy of Sciences

Graduated from Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China

Vitenskapelig artikkel

• Zhou, Fan; Vahokoski, Juha; Langeland, Nina et al. (2024). Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection. (ekstern lenke)
• Waldock, Joanna; Remarque, Edmond J.; Zheng, Lingyi et al. (2023). Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study. (ekstern lenke)
• Beukema, Martin; Gong, Shuran; Al-Jaawni, Kasem et al. (2023). Prolonging the delivery of influenza virus vaccine improves the quantity and quality of the induced immune responses in mice. (ekstern lenke)
• Hansen, Lena; Brokstad, Karl Albert; Bansal, Amit et al. (2023). Durable immune responses after BNT162b2 vaccination in home-dwelling old adults. (ekstern lenke)
• Onyango, Therese Bredholt; Zhou, Fan; Bredholt, Geir et al. (2023). SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients. (ekstern lenke)
• Wolff, Anette Susanne Bøe; Hansen, Lena; Grytaas, Marianne Aardal et al. (2023). Vaccination prevents severe COVID-19 outcome in patients with neutralizing type 1 interferon autoantibodies. (ekstern lenke)
• Rim, Sehee; Sakkestad, Sunniva Todnem; Zhou, Fan et al. (2023). Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. (ekstern lenke)
• Tran, Trung; Vaage, Eline Benno; Mehta, Adi et al. (2022). Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants. (ekstern lenke)
• Ertesvåg, Nina Urke; Sakkestad, Sunniva Todnem; Zhou, Fan et al. (2022). Persistent Fever and Positive PCR 90 Days Post-SARS-CoV-2 Infection in a Rituximab-Treated Patient: A Case of Late Antiviral Treatment. (ekstern lenke)
• Sicca, Federica; Sakorafa, Eleni; de Jonge, Anouk et al. (2022). The evolution of humoral immune responses to past and novel influenza virus strains gives evidence for antigenic seniority. (ekstern lenke)
• Ertesvåg, Nina Urke; Xiao, Julie; Zhou, Fan et al. (2022). A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern. (ekstern lenke)
• Bernard, Marie-Clotilde; Waldock, Joanna; Commandeur, Sylvie et al. (2022). Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study. (ekstern lenke)
• Zimmermann, Julie; Schmidt, Signe Tandrup; Trebbien, Ramona et al. (2022). A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease. (ekstern lenke)
• Mohn, Kristin Greve-Isdahl; Bredholt, Geir; Zhou, Fan et al. (2022). Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients. (ekstern lenke)
• Ekanger, Camilla Tvedt; Zhou, Fan; Bohan, Dana et al. (2022). Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 respiratory virus. (ekstern lenke)
• Fjelltveit, Elisabeth Berg; Blomberg, Bjørn; Kuwelker, Kanika et al. (2022). Symptom Burden and Immune Dynamics 6 to 18 Months Following Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection (SARS-CoV-2): A Case-control Study. (ekstern lenke)
• Blomberg, Bjørn; Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert et al. (2021). Long COVID in a prospective cohort of home-isolated patients. (ekstern lenke)
• Kuwelker, Kanika; Zhou, Fan; Blomberg, Bjørn et al. (2021). Attack rates amongst household members of outpatients with confirmed COVID-19 in Bergen, Norway: A case-ascertained study. (ekstern lenke)
• Hansen, Lena; Zhou, Fan; Amdam, Håkon et al. (2021). Repeated Influenza Vaccination Boosts and Maintains H1N1pdm09 Neuraminidase Antibody Titers. (ekstern lenke)
• Amdam, Håkon; Madsen, Anders; Zhou, Fan et al. (2021). Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014). (ekstern lenke)
• Zhou, Fan; Hansen, Lena; Pedersen, Gabriel Kristian et al. (2021). Matrix M Adjuvanted H5N1 Vaccine Elicits Broadly Neutralizing Antibodies and Neuraminidase Inhibiting Antibodies in Humans That Correlate With In Vivo Protection. (ekstern lenke)
• Carreño, Juan Manuel; McDonald, Jacqueline U.; Hurst, Tara et al. (2020). Development and assessment of a pooled serum as candidate standard to measure influenza a virus group 1 hemagglutinin stalk-reactive antibodies. (ekstern lenke)
• Trieu, Mai Chi; Bansal, Amit; Madsen, Anders et al. (2020). SARS-CoV-2-specific neutralizing antibody responses in Norwegian healthcare workers after the first wave of COVID-19 pandemic: a prospective cohort study. (ekstern lenke)
• Jalloh, Sarah Larteley Lartey; Zhou, Fan; Brokstad, Karl Albert et al. (2020). Live-attenuated influenza vaccine induces tonsillar follicular T helper cell responses that correlate with antibody induction. (ekstern lenke)
• Madsen, Anders; Azimi, Linda; Tete, Sarah et al. (2019). No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination. (ekstern lenke)
• Islam, Shahinul; Zhou, Fan; Jalloh, Sarah Larteley Lartey et al. (2019). Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination. (ekstern lenke)
• Trieu, Mai Chi; Zhou, Fan; Jalloh, Sarah Larteley Lartey et al. (2018). Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years. (ekstern lenke)
• Brokstad, Karl Albert; Fredriksen, Marita; Zhou, Fan et al. (2018). T follicular-like helper cells in the peripheral blood of patients with primary Sjögren's syndrome. (ekstern lenke)
• Trieu, Mai Chi; Jul-Larsen, Åsne; Sævik, Marianne et al. (2018). Antibody responses to influenza A/H1N1pdm09 virus after pandemic and seasonal influenza vaccination in healthcare workers: A 5-year follow-up study. (ekstern lenke)
• Mohn, Kristin Greve Isdahl; Zhou, Fan; Brokstad, Karl Albert et al. (2017). Boosting of cross-reactive and protection-associated T cells in children after live attenuated influenza vaccination. (ekstern lenke)
• Islam, Shahinul; Mohn, Kristin Greve Isdahl; Krammer, Florain et al. (2017). Influenza A haemagglutinin specific IgG responses in children and adults after seasonal trivalent live attenuated influenza vaccination. (ekstern lenke)
• Andersen, Tor Kristian; Zhou, Fan; Cox, Rebecca Jane et al. (2017). A DNA vaccine that targets hemagglutinin to antigen-presenting cells protects mice against H7 influenza. (ekstern lenke)
• Trieu, Mai Chi; Zhou, Fan; Jalloh, Sarah Larteley Lartey et al. (2016). Long-term maintenance of the influenza-specific cross-reactive memory CD4+ T-cell responses following repeated annual influenza vaccination.. (ekstern lenke)
• Trondsen, Monica; Aqrawi, Lara Adnan; Zhou, Fan et al. (2015). Induction of local secretory IgA and multifunctional CD4+ T-helper cells following intranasal immunization with a H5N1 whole inactivated influenza virus vaccine in BALB/c mice. (ekstern lenke)
• Lartey, Sarah Larteley; Pathirana, Rishi; Zhou, Fan et al. (2015). Single dose vaccination of the ASO3-adjuvanted A (H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains. (ekstern lenke)

Errata

• Tran, Trung; Vaage, Eline Benno; Mehta, Adi et al. (2023). Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants (npj Vaccines, (2022), 7, 1, (174), 10.1038/s41541-022-00586-7). (ekstern lenke)
• Trieu, Mai Chi; Zhou, Fan; Jalloh, Sarah Larteley Lartey et al. (2018). Publisher Correction: Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years. (ekstern lenke)

Brev til redaktøren

• Mohn, Kristin Greve-Isdahl; Bredholt, Geir; Onyango, Therese Bredholt et al. (2023). SARS-CoV-2 infection induces long-lived B and T-cell responses up to 15 months post-infection, irrespective of disease severity. (ekstern lenke)

Vitenskapelig foredrag

• Rim, Sehee; Sakkestad, Sunniva Todnem; Zhou, Fan et al. (2022). Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. (ekstern lenke)
• Rim, Sehee; Sakkestad, Sunniva Todnem; Zhou, Fan et al. (2019). Comprehensive characterization and kinetics of circulating lymphocytes in human volunteers experimentally infected with enterotoxigenic Escherichia coli. (ekstern lenke)
• Mohn, Kristin Greve Isdahl; Cox, Rebecca Jane; Zhou, Fan et al. (2015). Cellular immune responses after live attenuated influenza vaccination in children, a clinical trial.. (ekstern lenke)

Poster

• Hansen, Lena; Zhou, Fan; Amdam, Håkon et al. (2019). Neuraminidase antibody responses after pandemic and seasonal influenza vaccinations: a five-year study. (ekstern lenke)
• Hansen, Lena; Zhou, Fan; Cox, Rebecca Jane (2019). Neuraminidase Antibody Responses After Pandemic And Seasonal Vaccination: A Five-Year Study. (ekstern lenke)
• Rim, Sehee; Sakkestad, Sunniva Todnem; Skavland, Jørn et al. (2018). Comprehensive characterization of circulating T follicular helper cells and plasmablasts in human volunteers experimentally infected with enterotoxigenic Escherichia coli. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Mohn, Kristin Greve Isdahl; Zhou, Fan (2018). Clinical expectations for better influenza virus vaccines - perspectives from the young investigators' point of view. (ekstern lenke)
• Zhou, Fan; Trieu, Mai Chi; Davies, Richard Allan et al. (2018). Improving influenza vaccines: challenges to effective implementation. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

1. To characterized in-depth the de novo SARS-CoV-2 specific antibody responses and the boosting of HCoV-reactive antibodies after SARS-CoV-2 vaccination and infection.

2. To assess the magnitude and breadth of immuntiy towards the emerging highly pathogenic avian H5N1 influenza virus.

3. To study the influenza and RSV specific immune responses in vaccination and/or infected individuals.