Vitenskapelig artikkel

• Ji, Jianxiong; Ding, Kaikai; Cheng, Bo et al. (2024). Radiotherapy-Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth. (ekstern lenke)
• Xue, Zhiwei; Liu, Junzhi; Xing, Wenchen et al. (2024). Hypoxic glioma-derived exosomal miR-25-3p promotes macrophage M2 polarization by activating the PI3K-AKT-mTOR signaling pathway. (ekstern lenke)
• Sun, Yanfei; Mu, Guangjing; Zhang, Xuehai et al. (2024). Metabolic modulation of histone acetylation mediated by HMGCL activates the FOXM1/β-catenin pathway in glioblastoma. (ekstern lenke)
• Xue, Zhiyi; Zhang, Yan; Zhao, Ruiqi et al. (2024). The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions. (ekstern lenke)
• Zhao, Feihu; Yao, Zhong; Li, Yaquan et al. (2024). Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability. (ekstern lenke)
• Wang, Jiwei; Chen, Anbin; Xue, Zhiwei et al. (2023). BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma. (ekstern lenke)
• Li, Zhiwei; Qi, Ye; Sun, Lei et al. (2023). Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration. (ekstern lenke)
• Liu, Xuemeng; Hu, Yaotian; Xue, Zhiyi et al. (2023). Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the PDGFRA/MEK/ERK signaling pathway. (ekstern lenke)
• Che, Tongtong; Wang, Xiuying; Zhao, Kun et al. (2023). AMNet: Adaptive multi-level network for deformable registration of 3D brain MR images. (ekstern lenke)
• Li, Yaquan; Liu, Xuemeng; Zhao, Feihu et al. (2023). Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma. (ekstern lenke)
• Hu, Yaotian; Zhou, Wenjing; Xue, Zhiyi et al. (2022). Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2. (ekstern lenke)
• Zhang, Shouji; Zhao, Shulin; Qi, Yanhua et al. (2022). SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner. (ekstern lenke)
• Chen, Anbin; Kristiansen, Cecilie Katrin; Høyland, Lena Elise et al. (2022). POLG mutations lead to abnormal mitochondrial remodeling during neural differentiation of human pluripotent stem cells via SIRT3/AMPK pathway inhibition. (ekstern lenke)
• Yang, Xu; Zhang, Yan; Xue, Zhiwei et al. (2022). TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein. (ekstern lenke)
• Cheng, Bo; Ding, Kaikai; Chen, Pengxiang et al. (2022). Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer. (ekstern lenke)
• Zhang, Xun; Yao, Zhong; Xue, Zhiyi et al. (2022). Resibufogenin Targets the ATP1A1 Signaling Cascade to Induce G2/M Phase Arrest and Inhibit Invasion in Glioma. (ekstern lenke)
• Qi, Yanhua; Jin, Chuandi; Qiu, Wei et al. (2022). The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs. (ekstern lenke)
• Wang, Xu; Han, Mingzhi; Wang, Shuai et al. (2022). Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention. (ekstern lenke)
• Kong, Yang; Xue, Zhiwei; Wang, Haiying et al. (2022). Identification of BST2 Contributing to the Development of Glioblastoma Based on Bioinformatics Analysis. (ekstern lenke)
• Hu, Yaotian; Xue, Zhiyi; Qiu, Chen et al. (2022). Knockdown of NUSAP1 inhibits cell proliferation and invasion through downregulation of TOP2A in human glioblastoma. (ekstern lenke)
• Wang, Chenglong; Zhao, Zhimin; Qi, Qichao et al. (2021). miR-6858 plays a key role in the process of melatonin inhibition of the malignant biological behavior of glioma. (ekstern lenke)
• Vareecal Joseph, Justin; Magaut, Capucine R.; Storevik, Simon Humberto et al. (2021). TGF-β promotes microtube formation in glioblastoma through thrombospondin 1. (ekstern lenke)
• Luo, Tao; Ding, Kaikai; Ji, Jianxiong et al. (2021). Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway. (ekstern lenke)
• Qiu, Wei; Guo, Xiaofan; Li, Boyan et al. (2021). Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells. (ekstern lenke)
• Wu, Ye; Jin, Weili; Wang, Qixue et al. (2021). Precise editing of FGFR3-TACC3 fusion genes with CRISPR-Cas13a in glioblastoma. (ekstern lenke)
• Chen, Anbin; Kristiansen, Cecilie Katrin; Hong, Yu et al. (2021). Nicotinamide riboside and metformin ameliorate mitophagy defect in induced pluripotent stem cell-derived astrocytes with POLG mutations. (ekstern lenke)
• Lu, Di; Yang, Ning; Wang, Shuai et al. (2021). Identifying the predictive role of oxidative stress genes in the prognosis of glioma patients. (ekstern lenke)
• Qiu, Chen; Zhang, Xin; Huang, Bin et al. (2020). Disulfiram, a ferroptosis inducer, triggers lysosomal membrane permeabilization by up-regulating ros in glioblastoma. (ekstern lenke)
• Zheng, Jingfang; Su, Zhiying; Kong, Yang et al. (2020). LncRNAs Predicted to Interfere With the Gene Regulation Activity of miR-637 and miR-196a-5p in GBM. (ekstern lenke)
• Ji, Jianxiong; Ding, Kaikai; Luo, Tao et al. (2020). TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα. . (ekstern lenke)
• Yao, Zhong; Zhang, Xun; Zhao, Feihu et al. (2020). Ursodeoxycholic Acid Inhibits Glioblastoma Progression via Endoplasmic Reticulum Stress Related Apoptosis and Synergizes with the Proteasome Inhibitor Bortezomib. (ekstern lenke)
• Zhang, Xin; Ding, Kaikai; Ji, Jianxiong et al. (2020). Trifluoperazine prolongs the survival of experimental brain metastases by STAT3-dependent lysosome membrane permeabilization. . (ekstern lenke)
• Zhang, Yulin; Fu, Xiao; Jia, Junsheng et al. (2020). Glioblastoma Therapy Using Codelivery of Cisplatin and Glutathione Peroxidase Targeting siRNA from Iron Oxide Nanoparticles. (ekstern lenke)
• Kong, Yang; Feng, Zichao; Zhang, Yulin et al. (2020). Identification of immune-related genes contributing to the development of glioblastoma using weighted gene co-expression network analysis. . (ekstern lenke)
• Ji, Jianxiong; Ding, Kaikai; Luo, Tao et al. (2019). PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1. (ekstern lenke)
• Han, Mingzhi; Wang, Shuai; Zhao, Wen-Bo et al. (2019). Immune checkpoint molecule herpes virus entry mediator is overexpressed and associated with poor prognosis in human glioblastoma. (ekstern lenke)
• Feng, Zichao; Zhou, Wenjing; Wang, Jiwei et al. (2019). Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma.. (ekstern lenke)
• Han, Mingzhi; Wang, Shuai; Yang, Ning et al. (2019). Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma.. (ekstern lenke)
• Ji, Jianxiong; Xu, Ran; Ding, Kaikai et al. (2019). Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-kappa B Signaling. (ekstern lenke)
• Han, Mingzhi; Wang, Shuai; Fritah, Sabrina et al. (2019). Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling. (ekstern lenke)
• Qian, Mingyu; Wang, Shaobo; Guo, Xiaofan et al. (2019). Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways. (ekstern lenke)
• Ding, Kaikai; Ji, Jianxiong; Zhang, Xin et al. (2019). RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation. (ekstern lenke)
• Kong, Yang; Feng, Zichao; Chen, Anjing et al. (2019). The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma. (ekstern lenke)
• Li, Haoyuan; Zhang, Yanming; Liu, Shangming et al. (2019). Melatonin enhances proliferation and modulates differentiation of neural stem cells via autophagy in hyperglycemia. (ekstern lenke)
• Guo, Xiaofan; Qiu, Wei; Wang, Jian et al. (2018). Glioma exosomes mediate the expansion and function of myeloid‐derived suppressor cells through microRNA‐29a/Hbp1 and microRNA‐92a/Prkar1a pathways. (ekstern lenke)
• Johannessen, Tor-Christian Aase; Hasan-Olive, Md Mahdi; Zhu, Huaiyang et al. (2018). Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. (ekstern lenke)
• Han, Mingzhi; Xu, Ran; Wang, Shuai et al. (2018). Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion. (ekstern lenke)
• Wang, Jiwei; Qi, Qichao; Zhou, Wenjing et al. (2018). Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. (ekstern lenke)
• Zhang, Xin; Wang, Xuehai; Xu, Ran et al. (2018). YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma. (ekstern lenke)
• Zhou, Wenjing; Wang, Jiwei; Qi, Qichao et al. (2018). Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. (ekstern lenke)
• Ji, Jianxiong; Xu, Ran; Zhang, Xin et al. (2018). Actin like-6A promotes glioma progression through stabilization of transcriptional regulators YAP/TAZ article. (ekstern lenke)
• Xu, Ran; Han, Mingzhi; Xu, Yangyang et al. (2017). Coiled-coil domain containing 109B is a HIF1?-regulated gene critical for progression of human gliomas. (ekstern lenke)
• Xia, Tongliang; Huang, Bin; Ni, Shilei et al. (2017). The combination of db-cAMP and ChABC with poly(propylene carbonate) microfibers promote axonal regenerative sprouting and functional recovery after spinal cord hemisection injury. (ekstern lenke)
• Xu, Yangyang; Zhang, Lin; Wei, Yuzhen et al. (2017). Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes hypoxia-induced glioma migration and invasion. (ekstern lenke)
• Han, Ming-Zhi; Xu, Ran; Xu, Yang-Yang et al. (2017). TAGLN2 is a candidate prognostic biomarker promoting tumorigenesis in human gliomas. (ekstern lenke)
• Zhang, Chao; Zhang, Xin; Xu, Ran et al. (2017). TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells' invasion. (ekstern lenke)
• Yang, Ruowen; Wang, Jian; Zhang, Tianyu et al. (2017). Change in the relationship between the Australian summer monsoon circulation and boreal summer precipitation over Central China in the late 1990s. (ekstern lenke)
• Zhao, Peng; Chen, Anjing; Qi, Qichao et al. (2017). Impact of VEGFA polymorphisms on glioma risk in Chinese. (ekstern lenke)
• Zhao, Peng; Feng, Zichao; Qi, Qichao et al. (2017). Increased NG2 AND SOX2 expression is associated with high-grade choroid plexus tumors. (ekstern lenke)
• Han, Ming-Zhi; Bin, Huang; Chen, An-Jing et al. (2017). High expression of RAB43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. (ekstern lenke)
• Zhu, Huaiyang; Leiss, Lina Wik; Yang, Ning et al. (2017). Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy. (ekstern lenke)
• Leiss, Lina Wik; Mutlu, Ercan; Øyan, Anne Margrete et al. (2017). Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts. (ekstern lenke)
• Guo, Xing; Xu, Shugang; Gao, Xiao et al. (2017). Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells. (ekstern lenke)
• Zhang, Xin; Huang, Qibing; Wang, Xuehai et al. (2017). Bufalin enhances radiosensitivity of glioblastoma by suppressing mitochondrial function and DNA damage repair. (ekstern lenke)
• Xu, Ran; Ji, Jianxiong; Zhang, Xin et al. (2017). PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT. (ekstern lenke)
• Zhang, Xin; Xu, Ran; Zhang, Chao et al. (2017). Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination. (ekstern lenke)
• Wang, Benlin; Li, Haoyuan; Yao, Qingyu et al. (2016). Local in vitro delivery of rapamycin from electrospun PEO/PDLLA nanofibers for glioblastoma treatment. (ekstern lenke)
• Liu, Ming; Wang, Jiwei; Qi, Qichao et al. (2016). Nitidine chloride inhibits the malignant behavior of human glioblastoma cells by targeting the PI3K/AKT/mTOR signaling pathway. (ekstern lenke)
• Qi, Qichao; Wang, Jiwei; Huang, Bin et al. (2016). Association of HOTAIR polymorphisms rs4759314 and rs920778 with cancer susceptibility on the basis of ethnicity and cancer type. (ekstern lenke)
• Liu, Ming; Wang, Jian; Huang, Bin et al. (2016). Oleuropein inhibits the proliferation and invasion of glioma cells via suppression of the AKT signaling pathway. (ekstern lenke)
• Zhang, Chao; Chen, Wenliang; Zhang, Xin et al. (2016). Galunisertib inhibits glioma vasculogenic mimicry formation induced by astrocytes. (ekstern lenke)
• Chen, Weiliang; Xia, Tongliang; Wang, Donghai et al. (2016). Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14. (ekstern lenke)
• Guo, Xiaofan; Xue, Hao; Shao, Qianqian et al. (2016). Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR. (ekstern lenke)
• Wang, Jiwei; Qi, Qichao; Feng, Zichao et al. (2016). Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway. (ekstern lenke)
• Xiong, Yu; Gao, Xusheng; Zhu, Huaiyang et al. (2016). Role of medical thoracoscopy in the treatment of tuberculous pleural effusion. (ekstern lenke)
• Xue, Hao; Zhang, Jinsen; Guo, Xing et al. (2016). CREBRF is a potent tumor suppressor of glioblastoma by blocking hypoxia-induced autophagy via the CREB3/ATG5 pathway. (ekstern lenke)
• Qi, Qichao; Wang, Jiwei; Chen, Anjing et al. (2016). Associations of five polymorphisms in the CD44 gene with cancer susceptibility in Asians. (ekstern lenke)
• Sleire, Linda; Skeie, Bente Sandvei; Netland, Inger Anne et al. (2015). Drug repurposing: Sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc<sup>-</sup>, leading to glutathione depletion. (ekstern lenke)
• Yang, Ning; Huang, Bin; Tsinkalovsky, Oleg et al. (2014). A novel GFP nude rat model to investigate tumor-stroma interactions. (ekstern lenke)
• Jarzabek, Monika A.; Amberger-Murphy, Verena; Callanan, John J. et al. (2014). Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models. (ekstern lenke)
• Rygh, Cecilie Brekke; Wang, Jian; Thuen, Marte et al. (2014). Dynamic Contrast Enhanced MRI Detects Early Response to Adoptive NK Cellular Immunotherapy Targeting the NG2 Proteoglycan in a Rat Model of Glioblastoma. (ekstern lenke)
• Brekke, Cecilie; Wang, Jian; Thuen, Marte et al. (2014). Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. (ekstern lenke)
• Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak et al. (2014). Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.. (ekstern lenke)
• Yang, Ning; Yan, Tao; Zhu, Huaiyang et al. (2014). A co-culture model with brain tumor-specific bioluminescence demonstrates astrocytes-induced drug resistance in glioblastoma.. (ekstern lenke)
• Poli, Aurélie; Wang, Jian; Domingues, Olivia et al. (2013). Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival. (ekstern lenke)
• Klink, Barbara; Miletic, Hrvoje; Stieber, Daniel et al. (2013). A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. (ekstern lenke)
• Skeie, Bente Sandvei; Wang, Jian; Dodoo, Ernest et al. (2013). Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a Human GBM Xenograft Model. (ekstern lenke)
• Talasila, Krishna Mukharji; Soentgerath, Anke; Euskirchen, Philipp et al. (2013). EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. (ekstern lenke)
• Jacobsen, Hege; Sleire, Linda; Wang, Jian et al. (2013). Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments. (ekstern lenke)
• Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian et al. (2012). Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. (ekstern lenke)
• Viel, Thomas; Talasila, Krishna Mukharji; Monfared, Parisa et al. (2012). Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI. (ekstern lenke)
• Willingham, Stephen B.; Volkmer, Jens-Peter; Gentles, Andrew J. et al. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. (ekstern lenke)
• Keunen, Olivier; Johansson, Mikael; Oudin, Anaîs et al. (2011). Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. (ekstern lenke)
• Wang, Jian; Daphu, Inderjit Kaur; Pedersen, Paal-Henning et al. (2011). A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. (ekstern lenke)
• Yan, Tao; Skaftnesmo, Kai Ove; Leiss, Lina Wik et al. (2011). Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. (ekstern lenke)
• Wang, Jian; Svendsen, Agnete; Kmiecik, Justyna et al. (2011). Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma. (ekstern lenke)
• Goplen, Dorota; Bougnaud, Sébastien; Rajcevic, Uros et al. (2010). alpha B-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells. (ekstern lenke)
• Prestegarden, Lars; Svendsen, Agnete; Wang, Jian et al. (2010). Glioma cell populations grouped by different cell type markers drive brain tumor growth. (ekstern lenke)
• Huszthy, Peter Csaba; Immervoll, Heike ; Wang, Jian et al. (2010). Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment. (ekstern lenke)
• Johannessen, Tor-Christian Aase; Wang, Jian; Skaftnesmo, Kai Ove et al. (2009). Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. (ekstern lenke)
• Thulin, Asa; Ringvall, Maria; Dimberg, Anna et al. (2009). Activated Platelets Provide a Functional Microenvironment for the Antiangiogenic Fragment of Histidine-Rich Glycoprotein. (ekstern lenke)
• Rajcevic, Uros; Petersen, Kjell; Knol, Jaco C et al. (2009). iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype. (ekstern lenke)
• Wang, Jian; Miletic, Hrvoje; Sakariassen, Per Øystein et al. (2009). A reproducible brain tumour model established from human glioblastoma biopsies. (ekstern lenke)
• Thorsen, Frits Alan; Jirak, Daniel; Wang, Jian et al. (2008). Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. (ekstern lenke)
• Chekenya, Martha; Krakstad, Camilla; Svendsen, Agnete et al. (2008). The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. (ekstern lenke)
• Huszthy, Peter Csaba; Goplen, Dorota; Thorsen, Frits Alan et al. (2008). Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. (ekstern lenke)
• Wang, Jian; Sakariassen, Per Øystein; Tsinkalovsky, Oleg et al. (2008). CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. (ekstern lenke)
• Thorsen, Frits Alan; Enger, Per Øyvind; Wang, Jian et al. (2007). Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. (ekstern lenke)
• Piepoli, Tiziana; Jakupoglu, Cemile; Gu, Wenli et al. (2006). Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. (ekstern lenke)
• Goplen, Dorota; Wang, Jian; Enger, Per Øyvind et al. (2006). Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. (ekstern lenke)
• Sundlisæter, Eirik; Wang, Jian; Sakariassen, Per Øystein et al. (2006). Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. (ekstern lenke)
• Sakariassen, Per Øystein; Prestegarden, Lars; Wang, Jian et al. (2006). Angiogenesis-independent tumor growth mediated by stem-like cancer cells. (ekstern lenke)

Errata

• Chen, Weiliang; Xia, Tongliang; Wang, Donghai et al. (2022). Erratum: Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14 (Oncotarget (2016) 7 (62425–62438) DOI: 10.18632/oncotarget.11515). (ekstern lenke)
• Wang, Chenglong; Zhao, Zhimin; Qi, Qichao et al. (2021). Corrigendum to “miR-6858 plays a key role in the process of melatonin inhibition of the malignant biological behavior of glioma” [J. Clin. Neurosci. 87 (2021) 137–146](S0967586821000886)(10.1016/j.jocn.2021.02.015). (ekstern lenke)
• Zhang, Chao; Zhang, Xin; Xu, Ran et al. (2021). Retraction Note: TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion. (ekstern lenke)
• Zhang, Xin; Wang, Xuehai; Xu, Ran et al. (2021). Correction to: YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma (Journal of Translational Medicine, (2018), 16, 1, (79), 10.1186/s12967-018-1451-5). (ekstern lenke)

Mastergradsoppgave

• Moreino, Shannon; Thorsen, Frits; Wang, Jian (2021). Development of 3D in vitro Interaction Models for the Evaluation and Treatment of Brain Metastases. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Xu, Yangyang; Zhang, Lin; Wei, Yuzhen et al. (2021). Correction: Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes hypoxia-induced glioma migration and invasion. (ekstern lenke)
• Zhang, Xin; Ding, Kaikai; Wang, Jian et al. (2018). Chemoresistance caused by the microenvironment of glioblastoma and the corresponding solutions. (ekstern lenke)
• Zhang, Xin; Wang, Jian; Li, Xingang et al. (2018). Lysosomes contribute to radioresistance in cancer. (ekstern lenke)

Brev til redaktøren

• Han, Ming-Zhi; Huang, Bin; Ni, Shi-Lei et al. (2020). A validated prognostic nomogram for patients with newly diagnosed lower-grade gliomas in a large-scale Asian cohort. (ekstern lenke)

Doktorgradsavhandling

• Zhu, Huaiyang; Wang, Jian (2016). Experimental modeling and therapeutic strategies in glioblastoma. (ekstern lenke)
• Wang, Jian (2008). Xenografted brain tumors for modelling glioma biology – a study of brain tumor initiating cells and phenotypic modulation in gliomas. (ekstern lenke)

Poster

• Rahman, Mohummad Aminur; Leiss, Lina Wik; Lellahi, Seyed Mohammad et al. (2015). The transcription factor POU3F2 is expressed in human gliomas and promotes tumorigenesis in vivo. (ekstern lenke)
• Johannessen, Tor-Christian Aase; Wang, Jian; Skaftnesmo, Kai Ove et al. (2009). Highly infiltrative brain tumors show reduced chemosensitivity associated with a stem cell-like phenotype. (ekstern lenke)

Sammendrag/abstract

• Talasila, Krishna Mukharji; Soentgerath, Anke; Euskirchen, Philipp et al. (2013). EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. (ekstern lenke)
• Brekke, Cecilie; Thuen, Marte; Poli, Aurélie et al. (2012). Early MRI findings of targeting the NG2 proteoglycan in GBM. (ekstern lenke)
• Jacobsen, Hege; Dicko, Aly; Wang, Jian et al. (2011). Separate analysis of the cancer and stroma cell populations from orthotopically implanted tumor biopsies in eGFP scid mice. (ekstern lenke)
• Keunen, Oliver; Johansson, M; Oudin, A et al. (2010). ANTI-ANGIOGENIC TREATMENT IN A CLINICALLY RELEVANT GLIOBLASTOMA MODEL REDUCES BLOOD FLOW AND INCREASES TUMOR CELL INVASION. (ekstern lenke)
• Chekenya, Martha; Wang, Jian; Poli, A et al. (2010). THERAPEUTIC TARGETING OF THE NG2 PROTEOGLYCAN WITH MAB 9.2.27 AND ADOPTIVELY TRANSFERRED NK CELLS LYSES HUMAN GLIOBLASTOMA MULTIFORME IN VIVO. (ekstern lenke)
• Sleire, Linda; Wang, Jian; Heggdal, Jan et al. (2010). SULFASALAZINE SENSITIZES GLIOBLASTOMA CELLS TO RADIATION TREATMENT. (ekstern lenke)
• Liang, Xiao; Labeed, FH; Abdallat, R et al. (2010). Rapid adherence to collagen IV enriches for tumour initiating cells. (ekstern lenke)
• Niclou, SP; Johansson, Mikael; Keunen, O et al. (2009). PHENOTYPIC AND PHYSIOLOGIC EFFECTS OF BEVACIZUMAB IN A HIGHLY INFILTRATIVE AND ANGIOGENIC HUMAN GLIOBLASTOMA MODEL. (ekstern lenke)
• Wang, Jian; Tsinkalovsky, Oleg; Svendsen, Agnete et al. (2009). Targeting the tumor stroma: a novel therapeutic strategy based on separate analysis of the malignant and stromal cell compartments in brain tumors. (ekstern lenke)
• Wang, Jian; Tsinkalovsky, Oleg; Zhao, P et al. (2009). TARGETING THE TUMOR STROMA: A NOVEL THERAPEUTIC STRATEGY BASED ON SEPARATE ANALYSIS OF THE MALIGNANT AND STROMAL CELL COMPARTMENTS IN BRAIN TUMORS. (ekstern lenke)
• Rajcevic, U; Peterson, K; Knol, Jaco C et al. (2009). MOLECULAR VARIATIONS IN TUMOR-HOST INTERACTIONS BETWEEN INVASIVE AND ANGIOGENIC PHENOTYPE IN HIGH-GRADE GLIOMAS. (ekstern lenke)
• Wang, Jian; Miletic, Hrvoje; Sakariassen, Per Øystein et al. (2009). PHENOTYPIC MODULATION OF EXPERIMENTAL GLIOMAS: PROGRESSION FROM GLIOMATOSIS CEREBRI-LIKE LESIONS TO GLIOBLASTOMA. (ekstern lenke)
• Prestegarden, Lars; Svendsen, Agnete; Wang, Jian et al. (2009). CD133-NEGATIVE GLIOMA SUBPOPULATIONS GROUPED BY DIFFERENT CELL TYPE MARKERS DISPLAY TUMORIGENICITY IN VIVO. (ekstern lenke)
• Huszthy, Peter Csaba; Wang, Jian; Enger, Per Øyvind et al. (2008). Human glioblastoma tissue engraftment in immunocompetent rodent hosts. (ekstern lenke)
• Prestegarden, Lars; Svendsen, Agnete; Wang, Jian et al. (2008). CD133-NEGATIVE GLIOMA SUBPOPULATIONS GROUPED BY DIFFERENT CELL TYPE MARKERS DISPLAY TUMORGENICITY IN VIVO. (ekstern lenke)
• Thorsen, Frits Alan; Daphu, Inderjit Kaur; Pedersen, Paal-Henning et al. (2008). DEVELOPMENT OF A NEW BRAIN METASTASES MODEL IN IMMUNODEFICIENT ANIMALS. (ekstern lenke)
• Goplen, Dorota; Wang, Jian; Tysnes, Berit Bølge et al. (2005). Bacitracin inhibits glioma cell migration and invasion in vitro. (ekstern lenke)
• Sakariassen, Per Øystein; Prestegarden, Lars; Wang, Jian et al. (2004). Forced differentiation suppresses the proliferative rate of cancer cells in brain tumours. (ekstern lenke)
• Enger, Per Øyvind; Sakariassen, Per Øystein; Skaftnesmo, Kai Ove et al. (2004). Angiogenesis-independent growth by brain tumor cells exhibiting cancer stem cell properties. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

1.         Poli A, Wang J, Domingues O, Yan T, Thuen M, Thorsen F, Rygh CB, McCormack E, Fischer W, Planaguma J, Hentges F, Pedersen PH, Zimmer J, Enger PØ, and Chekenya M. Targeting NG2 with mAb9.2.27 activated NK-cells promotes microglial cytotoxicity against GBM, prolonging survival in rats (Co-first author, Oncotarget. 2013 Sep;4(9):1527-46)

2.         Skeie BS, Wang J, Dodoo E, Heggdal JI, Grønli J, Sleire L, Bragstad S, Chekenya M, Mørk S, Pedersen PH, Enger PØ, and Ganz JC. Gamma Knife Surgery as monotherapy with clinically relevant doses Prolongs Survival in a Human GBM Xenograft Model. (Biomed Res Int. 2013;2013:139674. doi: 10.1155/2013/139674. Epub 2013 Nov 10).

3.         Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Brekka N, Nigro J, Lund-Johansen M, Mørk S, Enger PØ, Bjerkvig R and MiletiC H. EGFR activation promotes invasion and tumor development independent of angiogenesis. (Acta Neuropathologica, Epub 2013 Feb 22)

4.         Klink B, Miletic H, Stieber D, Huszthy P, Valenzuela JAC, Balss J, Wang J, Schubert M, Sakariassen PØ, Sundstrøm T, Torsvik A, Aarhus M, Mahesparan R, Deimling AV, Kaderali L, Niclou S, Schröck E, Bjerkvig R, Nigro J. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. (Plos one, Epub 2013 Mar 19)

5.         Jacobsen HK, Sleire L, Wang J, Netland IA, Mutlu E, Førde H, Pedersen PH, Gullberg Dand Enger PØ. Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments. (Cancer investigation, 2013 May;31(4):221-30)

6.         Kim DK, Wang J, Willingham SB, Martin R, Wernig G, and Weissman IL. Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells. Leukemia. 2012 May 30. doi: 10.1038/leu.2012.140. [Epub ahead of print]

7.         Viel T, Talasila T, Talasila KM, Monfared P, Wang J, Jikeli JfF, Waerzeggers Y, Neumaier B, Backes H, Brekka N, Thorsen F, Stieber D, Niclou SP, Winkeler A, Tavitian B, Hoehn M, Bjerkvig R, Miletic H, and Jacobs A. Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multi-modal µPET and µMRI. J Nucl Med. 2012 Jul;53(7):1135-45. Epub 2012 Jun 11.

8.         Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PO, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. CD47 Is A Therapeutic Target On Human Solid Tumor Cells. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. Epub 2012 Mar 26.

9.         Moen I, Jevne C, Wang J, Kalland KH, Chekenya M, Akslen LA, Sleire L, Enger PØ, Reed RK, Øyan AM and Stuhr L. Tumor-stroma interactions in red 4T1 mammary tumors in green mice with and without enhanced oxygenation. BMC Cancer. 2012 Jan 17;12:21.

10.       Yan T, Skaftnesmo KO, Leiss L, Sleire L, Wang J, Li XG, Enger PO. Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. BMC Cancer. 2011 Dec 20;11:524.

11.       Wang J, Svendsen A, Kmiecik J, Miletic H, Immervoll H, Planaguma J, Bjerkvig R, Enger PØ, Rygh CB,  Chekenya M. Targeting the NG2 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma. (PLoS One. 2011;6(7):e23062. Epub 2011 Jul 29).

12.       Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SAA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, Miletic H, Wang J, Stuhr L, Moen I, Brekke C, Bjerkvig B and Niclou1 SP. Bevacizumab reduces blood flow and increases tumor cell invasion in glioblastomas. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3749-54.

13.       Wang J, Daphu I, Pedersen PH, Miletic H, Hovland R, Mørk S, Bjerkvig R, Tiron C, McCormack E, Micklem D, Lorens JB, Immervoll H, Thorsen F. A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. Neuropathol Appl Neurobiol. 2011 Feb;37(2):189-205.

14.       Goplen D, Bougnaud S, Rajcevic U, Bøe SO, Skaftnesmo KO, Voges J, Enger PO, Wang J, Tysnes BB, Laerum OD, Niclou S, Bjerkvig R. {alpha}B-Crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells. Am J Pathol. 2010 Oct;177(4):1618-28. Epub 2010 Sep 2.

15.       Prestegarden L, Svendsen A, Wang J, Sleire L, Skaftnesmo KO, Bjerkvig R, Yan T, Askland L, Persson A, Sakariassen PØ, Enger PØ. Glioma cell populations grouped by different cell type markers drive brain tumor growth. Cancer Res. 2010 Jun 1; 70(11): 4274-9.

16.       Huszthy PC, Immervoll H, Wang J, Goplen D, Miletic H, Eide GE, Bjerkvig R. Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment. Gene Ther. 2010 Feb; 17(2): 202-16.

17.       Wang J, Miletic H, Per Ø Sakariassen, Peter C Huszthy, Hege Jacobsen, Narve Brekka, Xingang Li, Peng Zhao, Sverre Mørk, Martha Chekenya, Rolf Bjerkvig and Per Ø Enger. A standardised brain tumor model established from the human glioblastoma multiforme biopsies. BMC Cancer. 2009 Dec 29; 9:465.

18.       Thulin Å, Ringvall M, Dimberg A, Kårehed K, Väisänen T, Väisänen MR, Hamad O, Wang J, Bjerkvig R, Nilsson B, Pihlajaniemi T, Åkerud H, Pietras K, Jahnen-Dechent W, Siegbahn A, Olsson AK. Activated platelets provide a functional microenvironment for the anti-angiogenic fragment of histidine-rich glycoprotein. Mol Cancer Res. 2009 Nov; 7(11): 1792-802. Epub 2009 Nov 10.

19.       Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, Klychnikov O, Li KW, Pham TV, Wang J, Miletic H, Peng Z, Bjerkvig R, Jimenez CR, Niclou SP. iTRAQ based proteomic profiling reveals increased metabolic activity and cellular crosstalk in angiogenic compared to invasive Glioblastoma phenotype. Mol Cell Proteomics. 2009 Nov;8(11): 2595-612. Epub 2009 Aug 12.

20.      Johannessen TC, Wang J, Skaftnesmo KO, Sakariassen PØ, Enger PØ, Petersen K, Øyan AM, Kalland KH, Bjerkvig R, Tysnes BB. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. Neuropathol Appl Neurobiol. 2009 Aug; 35(4): 380-93.

21.       Thorsen F, Jirak D, Wang J, Sykova E, Bjerkvig R, Enger PØ, van der Kogel A, Hajek M. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. NMR Biomed. 2008 Oct; 21(8): 830-8.

22.       Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB. The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 2008 Sep 4; 27(39): 5182-94. Epub 2008 May 12.

23.       Huszthy PC, Goplen D, Thorsen F, Immervoll H, Wang J, Gutermann A, Miletic H, Bjerkvig R. Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. Clin Cancer Res. 2008 Mar 1; 14 (5): 1571-80.

24.       Wang J, Sakariassen PØ, Tsinkalovsky O, Immervoll H, Bøe SO, Svendsen A, Prestegarden L, Røsland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PØ. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer. 2008 Feb 15; 122 (4):761-8.

25.       Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A. 2006 Oct 31;103 (44):16466-71. Epub 2006 Oct 20.

26.       Goplen D, Wang J, Enger PØ, Tysnes BB, Terzis AJ, Laerum OD, Bjerkvig R. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Res. 2006 Oct 15; 66 (20): 9895-902.

27.       Thorsen F, Enger PØ, Wang J, Bjerkvig R, Pedersen PH. Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. J Neurooncol. 2007 Mar; 82 (1): 1-10. Epub 2006 Sep 6.

28.       Sundlisaeter E, Wang J, Sakariassen PØ, Marie M, Mathisen JR, Karlsen BO, Prestegarden L, Skaftnesmo KO, Bjerkvig R, Enger PØ. Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. Neuropathol Appl Neurobiol. 2006 Aug; 32 (4): 419-27.

29.       Piepoli T, Jakupoglu C, Gu W, Lualdi E, Suarez-Merino B, Poliani PL, Cattaneo MG, Ortino B, Goplen D, Wang J, Mola R, Inverardi F, Frassoni C, Bjerkvig R, Steinlein O, Vicentini LM, Brüstle O, Finocchiaro G. Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. Neuro Oncol. 2006 Apr; 8(2): 96-108. Epub 2006 Mar 2.

Book chapter: Wang, J. Terzis. A.J.A, Aboody, K. Enger, PO and Bjerkvig, R. Transplants for Glioblastoma In Cell Transplantation from Laboratory to Clinic, Elsevier Publishers, C. Halberstadt and D. Emerich eds. (2007)