Fagartikkel

• Hossain, Md Kaykobad; Unger, Lucas; Larsen, Ulrik et al. (2025). Mapping the initial effects of carcinogen-induced oncogenic transformation in the mouse bladder. (ekstern lenke)

Poster

• Unger, Lucas; Mathisen, Andreas Frøslev; Legøy, Thomas Aga et al. (2024). Deciphering the HNF1A and Hedgehog Signaling Crosstalk during Stem Cell Islet differentiation. (ekstern lenke)
• Sharmine, Shayla; Ghila, Luiza Mihaela; Chera, Simona (2024). Short-term effect of Somatostatin Modulators on Glycemic Control in MODY mice. (ekstern lenke)
• Unger, Lucas; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2024). Exploring hedgehog signaling and HNF1A Crosstalk in HNF1A-MODY stem cell islets. (ekstern lenke)
• Larsen, Ulrik; Mathisen, Andreas Frøslev; Kavli, Natalie Aasen et al. (2024). Investigating stress-induced islet cell proliferation following partial insulin-secreting β-cell ablation in mice . (ekstern lenke)
• Legøy, Thomas Aga; Unger, Lucas; Paulo, Joao A. et al. (2024). Exposure to Endocrine Disrupting Chemicals During Differentiation of HNF1A-MODY SC-islets has an Adverse Effect on Cell Fitness. (ekstern lenke)
• Hossain, Md Kaykobad; Altankhuyag, Altanchimeg; Legøy, Thomas Aga et al. (2024). Dynamic proteome profiling detects progressive alterations induced by BBN in the mouse bladder. (ekstern lenke)
• Hossain, Md Kaykobad; Altankhuyag, Altanchimeg; Legøy, Thomas Aga et al. (2024). Short-term BBN treatment alters the proteomic profile of mouse bladder. (ekstern lenke)
• Hossain, Md Kaykobad; Altankhuyag, Altanchimeg; Paulo, Joao et al. (2024). Investigating the tissue injury sensing and regenerative response in bladder urothelium. (ekstern lenke)
• Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Paulo, Joao et al. (2023). Human induced pluripotent stem cells as a model for environmental impact on diabetes. (ekstern lenke)
• Sharmine, Shayla; Legøy, Thomas Aga; Mathisen, Andreas Frøslev et al. (2023). Mapping islet architecture changes upon high fat diet challenge in a HNF1A-MODY mouse model. (ekstern lenke)
• Unger, Lucas; Legøy, Thomas Aga; Mathisen, Andreas Frøslev et al. (2023). Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. (ekstern lenke)
• Hossain, Md Kaykobad; Altankhuyag, Altanchimeg; Legøy, Thomas Aga et al. (2023). Mapping predictive bladder cancer signatures in a mouse model. (ekstern lenke)
• Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Scholz, Hanne et al. (2022). Molecular mechanisms affecting islet like cell fate acquisition in differentiating iPSC derived β-like cells”. (ekstern lenke)
• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2022). Hnf1a is a key regulator of β-cell identity and function. (ekstern lenke)
• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2022). Know your background, know your data. (ekstern lenke)
• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2022). Mind your background!. (ekstern lenke)
• Unger, Lucas; Ghila, Luiza Mihaela; Chera, Simona (2022). Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. (ekstern lenke)
• Unger, Lucas; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2022). Investigating the developmental role of HNF1A in human pancreatic islet cell differentiation. (ekstern lenke)
• Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra et al. (2021). Glucose during in vitro pancreatic beta cells regeneration: friends or for?. (ekstern lenke)

Faglig foredrag

• Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Paulo, Joao et al. (2024). Impact of diabetogenic signals from endocrine disrupting chemicals on a HNF1A cell model. (ekstern lenke)
• Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Paulo, Joao et al. (2024). Impact of endocrine disruptors on MODY3 iPSCs differentiation toward SC-islets – potential diabetogens. (ekstern lenke)
• Unger, Lucas; Legøy, Thomas Aga; Chera, Simona et al. (2023). Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human pancreatic islet cell differentiation. (ekstern lenke)
• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Larsen, Ulrik et al. (2023). Hnf1a Is An Important Regulator in Ageing And Maturation Of Pancreatic Islets. (ekstern lenke)
• Unger, Lucas; Legøy, Thomas Aga; Ghila, Luiza Mihaela et al. (2023). Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human induced pluripotent stem cell-derived pancreatic islet cell differentiation. (ekstern lenke)
• Ghila, Luiza Mihaela (2022). Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors. (ekstern lenke)
• Ghila, Luiza Mihaela (2022). Mapping tumour heterogeneity and predictive cancer signatures in vivo. (ekstern lenke)

Vitenskapelig foredrag

• Larsen, Ulrik; Mathisen, Andreas Frøslev; Kavli, Natalie Aasen et al. (2024). Partial insulin-producing β-cell ablation induces compensatory proliferation in mouse pancreatic islets. (ekstern lenke)
• Legøy, Thomas Aga; Unger, Lucas; Paulo, Joao A. et al. (2024). Environmental neglect: endocrine disruptors as underappreciated but important diabetogens in HNF1A-MODY cell model. (ekstern lenke)
• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Larsen, Ulrik et al. (2023). Islet maturation and ageing is governed by the Hnf1a transcription factor. (ekstern lenke)

Vitenskapelig artikkel

• Mathisen, Andreas Frøslev; Legøy, Thomas Aga; Larsen, Ulrik et al. (2024). The age-dependent regulation of pancreatic islet landscape is fueled by a HNF1a-immune signaling loop. (ekstern lenke)
• Mathisen, Andreas Frøslev; Larsen, Ulrik; Kavli, Natalie Aasen et al. (2024). Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption. (ekstern lenke)
• Unger, Lucas; Mathisen, Andreas Frøslev; Chera, Simona et al. (2024). The GLI code controls HNF1A levels during foregut differentiation. (ekstern lenke)
• Unger, Lucas; Ghila, Luiza Mihaela; Chera, Simona (2024). Targeted Gene Silencing by Using GapmeRs in Differentiating Human-Induced Pluripotent Stem Cells (hiPSC) Toward Pancreatic Progenitors. (ekstern lenke)
• Wang, Chencheng; Abadpour, Shadab; Olsen, Petter Angell et al. (2024). Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells. (ekstern lenke)
• Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Aleksandra et al. (2024). Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling. (ekstern lenke)
• Mathisen, Andreas Frøslev; Vacaru, Andrei Mircea; Unger, Lucas et al. (2024). Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset. (ekstern lenke)
• Vasicek, Jakub; Kuznetsova, Ksenia; Skiadopoulou, Dafni et al. (2024). ProHap enables human proteomic database generation accounting for population diversity. (ekstern lenke)
• Daian, Laura Maria; Tanko, Gabriela; Vacaru, Andrei Mircea et al. (2023). Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. (ekstern lenke)
• Mathisen, Andreas Frøslev; Abadpour, Shadab; Legøy, Thomas Aga et al. (2023). Global proteomics reveals insulin abundance as a marker of human islet homeostasis alterations. (ekstern lenke)
• Bhagchandani, Preksha; Chang, Charles A.; Zhao, Weichen et al. (2022). Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes. (ekstern lenke)
• Fernandez, Manuel Carrasco; Wang, Chencheng; Søviknes, Anne Mette et al. (2022). Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. (ekstern lenke)
• Ghila, Luiza; Legøy, Thomas Aga; Chera, Simona (2021). A Method for Encapsulation and Transplantation into Diabetic Mice of Human Induced Pluripotent Stem Cells (hiPSC)-Derived Pancreatic Progenitors. (ekstern lenke)
• Ghila, Luiza; Legøy, Thomas Aga; Mathisen, Andreas Frøslev et al. (2021). Chronically elevated exogenous glucose elicits antipodal effects on the proteome signature of differentiating human ipsc-derived pancreatic progenitors. (ekstern lenke)
• Legøy, Thomas Aga; Vethe, Heidrun; Abadpour, Shadab et al. (2020). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling . (ekstern lenke)
• Ghila, Luiza; Bjørlykke, Yngvild; Legøy, Thomas Aga et al. (2020). Bioinformatic analyses of miRNA-mRNA signature during hiPSC differentiation towards insulin-producing cells upon HNF4α mutation. (ekstern lenke)
• Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Salim, Zaidon et al. (2020). In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism. (ekstern lenke)
• Bjørlykke, Yngvild; Søviknes, Anne Mette; Hoareau, Laurence et al. (2019). Reprogrammed cells display distinct proteomic signaturesAssociated with colony morphology variability. (ekstern lenke)
• Legøy, Thomas Aga; Ghila, Luiza; Vethe, Heidrun et al. (2019). In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. (ekstern lenke)
• Furuyama, Kenichiro; Chera, Simona; van Gurp, Leon et al. (2019). Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (ekstern lenke)
• Vethe, Heidrun; Ghila, Luiza; Berle, Magnus et al. (2019). The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation. (ekstern lenke)
• Vethe, Heidrun; Legøy, Thomas Aga; Abadpour, Shadab et al. (2019). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. (ekstern lenke)
• Berle, Magnus; Ghila, Luiza; Vethe, Heidrun et al. (2018). Novel protein signatures suggest progression to muscular invasiveness in bladder cancer. (ekstern lenke)
• Cigliola, Valentina; Ghila, Luiza; Thorel, Fabrizio et al. (2018). Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells. (ekstern lenke)
• Vethe, Heidrun; Bjørlykke, Yngvild; Ghila, Luiza et al. (2017). Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. (ekstern lenke)

Leder

• Ghila, Luiza Mihaela; Furuyama, Kenichiro; Grey, Shane T. et al. (2022). Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms. (ekstern lenke)

Sammendrag/abstract

• Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra et al. (2021). 402.2: High Glucose Concentration Increases KATP Channel Activity but Suppresses Mitochondrial Respiration Ability in Insulin-producing Cells Regenerated From Stem Cells. (ekstern lenke)

Populærvitenskapelig artikkel

• Bhagchandani, Preksha; Chang, Charles; Zhao, Weichen et al. (2021). Islet transplantation tolerance in animals with defined histocompatibility and diabetes. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Cigliola, Valentina; Ghila, Luiza; Chera, Simona et al. (2019). Tissue repair brakes: A common paradigm in the biology of regeneration: Concise review. (ekstern lenke)

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