I am a neuroscientist and consultant neuroradiologist with an interest in understanding the disease course of major depression and anxiety disorders

Olga Therese Ousdal, MD PhD, is a consultant radiologist (20%) at Department of Radiology, Haukeland University Hospital, and an associate professor (100%) at Department of Biomedicine, Faculty of Medicine, University of Bergen. 

Mental disorders are dynamic disorders, where the type and degree of symptoms may vary over the disease course. I am interested in understanding the various disease transitions, including the transition from premorbid to active disease, from active disease to remission (following treatment) and from remission to relapse. I use my expertise in radiology in combination with clinical and multiomic data to address my research questions. 

Currently, I am leading the neuroimaging work packages at Center for Research on Neurostimulation treatments (UiB) https://www.uib.no/k1/163177/forskergruppe-nevrostimulerende-behandling-og-hjerneavbildning and The Bergen Center for Brain Plasticity (Helse Bergen/UiB) https://helse-bergen.no/en/bergen-center-for-brain-plasticity. I am also affiliated with the Neurotargeting group at Department of Biomedicine, UiB. https://www.uib.no/en/rg/neurotarg. 

Research awards:

Ousdal´s work has gained both national and international attention, and she is the recipient of the Marie Spångberg Award 2020 by the Norwegian Medical Association, the Falch Junior Award 2022 by The Faculty of Medicine, UiB  and the Young Scientist award 2022 by the Western Norway Regional Health Authority

For an overview of recent publications, please see Google scholar:

https://scholar.google.com/citations?user=opHslbAAAAAJ&hl=no

Students interested in pursuing a MS, MD with a research track or PhD within these areas of research are encouraged to contact me.

My research has been featured in local, national and international media:

• Bergens Tidende: https://www.bt.no/nyheter/innenriks/i/1q4BM/skanner-hodene-til-utoeya-ungdom
• TV2 news: https://www.tv2.no/a/13640828/,
• PsyPost: https://www.psypost.org/2018/01/study-terror-attack-survivors-suggests-trauma-can-long-term-influences-make-decisions-50645
• Dagens Medisin: https://www.dagensmedisin.no/artikler/2019/10/02/ny-elektrosjokk-forskning-forkaster-tidligere-teori/,
• Forskning.no: https://forskning.no/hjernen-psykiske-lidelser/elektrosjokk-oker-volumet-i-store-deler-av-hjernen/1573515,
• ABC news: https://www.abcnyheter.no/helse-og-livsstil/helse/2019/10/07/195616233/elektrosjokk-oker-volumet-i-store-deler-av-hjernen

MED4 - Human fysiologi

Jeg har tidligere undervist i biologisk psykologi (PROPSY303)

Vitenskapelig oversiktsartikkel/review

• Abe, Yoshifumi; Erchinger, Vera Jane; Ousdal, Olga Therese et al. (2024). Neurobiological mechanisms of electroconvulsive therapy for depression: Insights into hippocampal volumetric increases from clinical and preclinical studies. (ekstern lenke)
• Ousdal, Olga Therese; Brancati, Giulio E.; Kessler, Ute et al. (2021). The Neurobiological Effects of Electroconvulsive Therapy Studied Through Magnetic Resonance: What Have We Learned, and Where Do We Go?. (ekstern lenke)

Vitenskapelig artikkel

• Verdijk, Joey P. A. J.; van de Mortel, Laurens A.; ten Doesschate, Freek et al. (2024). Longitudinal resting-state network connectivity changes in electroconvulsive therapy patients compared to healthy controls. (ekstern lenke)
• Laroy, Maarten; Bouckaert, Filip; Ousdal, Olga Therese et al. (2024). Characterization of gray matter volume changes from one week to 6 months after termination of electroconvulsive therapy in depressed patients. (ekstern lenke)
• Hammar, Åsa Karin; Schmid, Marit Therese; Petersdotter, Linn et al. (2023). Inhibitory control as possible risk and/or resilience factor for the development of trauma related symptoms–a study of the Utøya terror attack survivors. (ekstern lenke)
• Almdahl, Ina Selseth; Martinussen, Liva Jenny; Ousdal, Olga Therese et al. (2023). Task-based functional connectivity reveals aberrance with the salience network during emotional interference in late-life depression. (ekstern lenke)
• Argyelan, Miklos; Deng, Zhi-De; Ousdal, Olga Therese et al. (2023). Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression. (ekstern lenke)
• Frid, Leila Marie; Kessler, Ute; Ousdal, Olga Therese et al. (2023). Neurobiological mechanisms of ECT and TMS treatment in depression: study protocol of a multimodal magnetic resonance investigation. (ekstern lenke)
• de Joode, Niels T.; Thorsen, Anders Lillevik; Vriend, Chris et al. (2023). Linking resting state metabolite concentrations in the dorsal anterior cingulate cortex to response inhibition in OCD, a combined fMRI-MRS study. (ekstern lenke)
• Lindanger, Line; Strand, Torbjørn; Mølster, Anders et al. (2022). Predictors of osteoarthritis development at a median 25 years after anterior cruciate ligament reconstruction using a patellar tendon autograft. (ekstern lenke)
• de Joode, Niels T.; Thorsen, Anders Lillevik; Vester, Eline L. et al. (2021). Longitudinal changes in neurometabolite concentrations in the dorsal anterior cingulate cortex after concentrated exposure therapy for obsessive-compulsive disorder. (ekstern lenke)
• Hagland, Pernille; Thorsen, Anders Lillevik; Ousdal, Olga Therese et al. (2021). Disentangling Within- and Between-Person Effects During Response Inhibition in Obsessive-Compulsive Disorder. (ekstern lenke)
• Brancati, Giulio Emilio; Brekke, Njål; Bartsch, Hauke et al. (2021). Short and long-term effects of single and multiple sessions of electroconvulsive therapy on brain gray matter volumes. (ekstern lenke)
• Brecke, Vilde; Thorsen, Anders Lillevik; Ousdal, Olga Therese et al. (2021). Diffusion Tensor Imaging Before and 3 Months After Concentrated Exposure Response Prevention in Obsessive-Compulsive Disorder. (ekstern lenke)
• Opel, Nils; Narr, Katherine L; Abbott, Christopher et al. (2021). Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy. (ekstern lenke)
• Takamiya, Akihiro; Dols, Annemiek; Emsell, Louise et al. (2021). Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration. (ekstern lenke)
• Thorsen, Anders Lillevik; de Wit, Stella J.; Hagland, Pernille et al. (2020). Stable inhibition-related inferior frontal hypoactivation and fronto-limbic hyperconnectivity in obsessive–compulsive disorder after concentrated exposure therapy. (ekstern lenke)
• Thorsen, Anders Lillevik; Vriend, Chris; de Wit, Stella J. et al. (2020). Effects of Bergen 4-day treatment on resting-state graph features in obsessive-compulsive disorder. (ekstern lenke)
• Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie et al. (2020). The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths. (ekstern lenke)
• Ousdal, Olga Therese; Kaufmann, Tobias; Kolskår, Knut-Kristian et al. (2019). Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging. (ekstern lenke)
• Ousdal, Olga Therese; Argyelan, Miklos; Narr, Katherine L. et al. (2019). Brain changes induced by electroconvulsive therapy are broadly distributed. (ekstern lenke)
• Ousdal, Olga Therese; Milde, Anne Marita; Craven, Alexander R. et al. (2018). Prefrontal glutamate levels predict altered amygdala–prefrontal connectivity in traumatized youths. (ekstern lenke)
• Moutoussis, Michael; Rutledge, Robb B.; Prabhu, Gita et al. (2018). Neural activity and fundamental learning, motivated by monetary loss and reward, are intact in mild to moderate major depressive disorder. (ekstern lenke)
• Ousdal, Olga Therese; Huys, Quentin J.; Milde, Anne Marita et al. (2017). The impact of traumatic stress on Pavlovian biases. (ekstern lenke)
• Grønli, Janne; Melinder, Annika Maria D; Ousdal, Olga Therese et al. (2017). Life threat and sleep disturbances in adolescents: a two-year follow-up of survivors from the 2011 Utøya, Norway, terror attack. (ekstern lenke)
• Rutledge, Robb B.; Moutoussis, Michael; Smittenaar, Peter et al. (2017). Association of neural and emotional impacts of reward prediction errors with major depression. (ekstern lenke)
• Rigoli, Francesco; Rutledge, Robb B.; Chew, Benjamin et al. (2016). Dopamine increases a value-independent gambling propensity. (ekstern lenke)
• Rahm, Christoffer; Liberg, Benny; Reckless, Greg et al. (2015). Negative symptoms in schizophrenia show association with amygdala volumes and neural activation during affective processing. (ekstern lenke)
• Crockett, Molly J.; Siegel, Jenifer Z.; Kurth-Nelson, Zeb et al. (2015). Dissociable Effects of Serotonin and Dopamine on the Valuation of Harm in Moral Decision Making. (ekstern lenke)
• Reckless, Greg; Ousdal, Olga Therese; SERVER, ANDRES et al. (2014). The left inferior frontal gyrus is involved in adjusting response bias during a perceptual decision-making task. (ekstern lenke)
• Ousdal, Olga Therese; Andreassen, Ole Andreas; SERVER, ANDRES et al. (2014). Increased amygdala and visual cortex activity and functional connectivity towards stimulus novelty is associated with state anxiety. (ekstern lenke)
• Ousdal, Olga Therese; Specht, Karsten; SERVER, ANDRES et al. (2014). The human amygdala encodes value and space during decision making. (ekstern lenke)
• Tesli, Martin Steen; Skåtun, Kristina Cecilie; Ousdal, Olga Therese et al. (2013). CACNA1C Risk Variant and Amygdala Activity in Bipolar Disorder, Schizophrenia and Healthy Controls. (ekstern lenke)
• Ousdal, Olga Therese; Brown, Andrew; Jensen, Jimmy Kristian et al. (2012). Associations Between Variants Near a Monoaminergic Pathways Gene (PHOX2B) and Amygdala Reactivity: A Genome-Wide Functional Imaging Study. (ekstern lenke)
• Ousdal, Olga Therese; Reckless, Greg; Andrès, Server et al. (2012). Effect of relevance on amygdala activation and association with the ventral striatum. (ekstern lenke)

Mastergradsoppgave

• Boehmisch, Florence Friederike; Ousdal, Olga Therese; Thorsen, Anders Lillevik (2023). Early life adversity and trajectories of cortical myelination. (ekstern lenke)

Errata

• Argyelan, Miklos; Deng, Zhi-De; Ousdal, Olga Therese et al. (2023). Correction: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression (Molecular Psychiatry, (2023), 10.1038/s41380-023-02318-2). (ekstern lenke)

Brev til redaktøren

• Ousdal, Olga Therese; Gjestad, Rolf; Oltedal, Leif (2021). Reply to: Clinical Relevance of Brain Changes After Electroconvulsive Therapy: Is There Really No Link at All?. (ekstern lenke)

Vitenskapelig foredrag

• Milde, Anne Marita; Grønli, Janne; Ousdal, Olga Therese (2018). Funn fra prosjektet 'Akutt stress på en hjerne I utvikling'. (ekstern lenke)
• Ousdal, Olga Therese; Lundervold, Astri; Westlye, Lars Tjelta et al. (2018). Longitudinal stability of the brain functional connectome is associated with episodic memory performance. (ekstern lenke)

Populærvitenskapelig artikkel

• Ousdal, Olga Therese (2015). Traumer: Hva kan terrorangrepet på Utøya lære oss?. (ekstern lenke)
• Ousdal, Olga Therese; Milde, Anne Marita (2013). To år etter terrorangrepet. Hvordan har Utøya-ungdommene det når hverdagen har kommet?. (ekstern lenke)

Poster

• Milde, Anne Marita; Ousdal, Olga Therese; Stavestrand, Silje Haukenes et al. (2014). Psychiatric long-term effects in Survivors from the terror attack at Utøya 22. July.. (ekstern lenke)
• Ousdal, Olga Therese; Milde, Anne Marita; Craven, Alexander R. et al. (2014). Emotional conflict Processing in Survivors of the 2011 Oslo and Utøya terror attack; Behavioural and fMRI data.. (ekstern lenke)
• Ousdal, Olga Therese; Hugdahl, Kenneth; Stavestrand, Silje Haukenes et al. (2014). The influence of action requirements and outcome valence on instrumental Learning after traumatic stress.. (ekstern lenke)

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