Vitenskapelig foredrag

• Skeie, Bente Sandvei; Bragstad, Sidsel Marit; PhD, Dorota Goplen, MD, et al. (2023). NCT04205357 – a phase I trial investigating Sulfasalazine as radiosensitizer in combination with Gamma Knife Radiosurgery for recurrent Glioblastoma and a Study protocol for a multicenter phase 2/3 trial.. (ekstern lenke)
• Bragstad, Sidsel Marit; Tveiten, Øystein Vesterli; BEHBAHANI, MAZIAR et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Bragstad, Sidsel Marit; Tveiten, Øystein Vesterli; BEHBAHANI, MAZIAR et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Skeie, Bente Sandvei; Bragstad, Sidsel Marit; Goplen, Dorota Katarzyna Pazdyk et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Skeie, Bente Sandvei; Bragstad, Sidsel Marit; PhD, Dorota Goplen, MD, et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Skeie, Bente Sandvei; Bragstad, Sidsel Marit; PhD, Dorota Goplen, MD, et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Skeie, Bente Sandvei; Bragstad, Sidsel Marit; Sarowar, Shahin et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Enger, Per Øyvind; Bragstad, Sidsel Marit; Heggdal, Jan Ingemann et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Enger, Per Øyvind; Bragstad, Sidsel Marit; Tveiten, Øystein Vesterli et al. (2022). Phase I trial of Sulfasalazine combined with Stereotactic Radiosurgery for recurrent Glioblastoma: Study protocol for NCT04205357. (ekstern lenke)
• Cirillo, Davide; Sarowar, Shahin; Adamsen, Tom Christian Holm et al. (2019). Synthesis of targeting molecules : PET and therapeutics. (ekstern lenke)
• Cirillo, Davide; Adamsen, Tom Christian Holm; Enger, Per Øyvind et al. (2018). Synthesis of targeting molecules as tracers for PET and anticancer pro-drugs: investigation of tumor drug distribution. (ekstern lenke)
• Cirillo, Davide; Adamsen, Tom Christian Holm; Enger, Per Øyvind et al. (2018). Synthesis of targeting molecules as tracers for PET and anticancer pro-drugs: investigation of tumor drug distribution. (ekstern lenke)
• Brekken, Christian; Enger, Per Øyvind; Enger, Per Øyvind et al. (2002). Endostatin Gene Transduction of Glioma Cells Modifies Brain Tumor Development: Assessment by Magnetic Resonance Imaging. (ekstern lenke)
• Skeie, Bente Sandvei; Enger, Per Øyvind; Skeie, Geir Olve et al. (2001). Gamma Knife Radiosurgery of meningiomas involving the cavernous sinus. (ekstern lenke)

Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

• Leiss, Lina Wik; Mutlu, Ercan; Rahman, Mohummad Aminur et al. (2022). Tumor–Host Interactions in Malignant Gliomas. (ekstern lenke)

Vitenskapelig artikkel

• Sarowar, Shahin; Cirillo, Davide; Játiva, Pablo et al. (2022). The styryl benzoic acid derivative DC10 potentiates radiotherapy by targeting the xCT-glutathione axis. (ekstern lenke)
• Schneider, Matthias; Vollmer, Lea; Potthoff, Anna-Laura et al. (2021). Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma. (ekstern lenke)
• Cirillo, Davide; Sarowar, Shahin; Enger, Per Øyvind et al. (2021). Structure–Activity Relationships Aided Design and Synthesis of xCT Antiporter Inhibitors. (ekstern lenke)
• Skeie, Bente Sandvei; Enger, Per Øyvind; Knisely, Jonathan et al. (2020). A simple score to estimate the likelihood of pseudoprogression vs. recurrence following stereotactic radiosurgery for brain metastases: The Bergen Criteria. (ekstern lenke)
• Navarro, Andrea Gras; Espedal, Heidi; Joseph, Justin Vareecal et al. (2019). Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival. (ekstern lenke)
• Leiss, Lina; Mega, Alessandro; Bontell, Thomas Olsson et al. (2019). Platelet‐derived growth factor receptor α/glial fibrillary acidic protein expressing peritumoral astrocytes associate with shorter median overall survival in glioblastoma patients. (ekstern lenke)
• Mega, Alessandro; Nilsen, Mette Hartmark; Leiss, Lina Wik et al. (2019). Astrocytes enhance glioblastoma growth. (ekstern lenke)
• Rahman, Mohummad Aminur; Navarro, Andrea Gras; Brekke, Jorunn et al. (2019). Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival. (ekstern lenke)
• Bragstad, Sidsel Marit; Flatebø, Marianne; Natvig, Gerd Karin et al. (2018). Predictors of quality of life and survival following Gamma Knife surgery for lung cancer brain metastases: a prospective study. (ekstern lenke)
• Wallmann, Tatjana; Zhang, Xing-Mei; Wallerius, Majken et al. (2018). Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity. (ekstern lenke)
• Leiss, Lina Wik; Mutlu, Ercan; Øyan, Anne Margrete et al. (2017). Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts. (ekstern lenke)
• Zhu, Huaiyang; Leiss, Lina Wik; Yang, Ning et al. (2017). Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy. (ekstern lenke)
• Niklasson, Mia; Maddalo, Ianluca; Sramkova, Zuzana et al. (2017). Membrane-depolarizing channel blockers induce selective glioma cell death by impairing nutrient transport and unfolded protein/amino acid responses. (ekstern lenke)
• Valentin, Mev Dominguez; Navarro, Andrea Gras; Rahman, Mohummad Aminur et al. (2016). Identification of a natural killer cell receptor allele that prolongs survival of cytomegalovirus-positive glioblastoma patients. (ekstern lenke)
• Netland, Inger Anne; Førde-Tislevoll, Hilde Elise; Sleire, Linda et al. (2016). Treatment with the PI3K inhibitor buparlisib (NVP-BKM120) suppresses the growth of established patient-derived GBM xenografts and prolongs survival in nude rats. (ekstern lenke)
• Eskilsson, Eskil; Røsland, Gro Vatne; Talasila, Krishna Mukharji et al. (2016). EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. (ekstern lenke)
• Skeie, Bente Sandvei; Eide, Geir Egil; Flatebø, Marianne et al. (2016). Quality of life is maintained using Gamma Knife radiosurgery: A prospective study of a brain metastases patient cohort. (ekstern lenke)
• Netland, Inger Anne; Førde-Tislevoll, Hilde Elise; Sleire, Linda et al. (2016). Dactolisib (NVP-BEZ235) toxicity in murine brain tumour models. (ekstern lenke)
• Sleire, Linda; Skeie, Bente Sandvei; Netland, Inger Anne et al. (2015). Drug repurposing: Sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc<sup>-</sup>, leading to glutathione depletion. (ekstern lenke)
• Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak et al. (2014). Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.. (ekstern lenke)
• Yang, Ning; Yan, Tao; Zhu, Huaiyang et al. (2014). A co-culture model with brain tumor-specific bioluminescence demonstrates astrocytes-induced drug resistance in glioblastoma.. (ekstern lenke)
• Torsvik, Anja; Stieber, Daniel; Enger, Per Øyvind et al. (2014). U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells. (ekstern lenke)
• Rygh, Cecilie Brekke; Wang, Jian; Thuen, Marte et al. (2014). Dynamic Contrast Enhanced MRI Detects Early Response to Adoptive NK Cellular Immunotherapy Targeting the NG2 Proteoglycan in a Rat Model of Glioblastoma. (ekstern lenke)
• Brekke, Cecilie; Wang, Jian; Thuen, Marte et al. (2014). Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. (ekstern lenke)
• Navarro, Andrea Gras; Kmiecik, Justyna; Leiss, Lina Wik et al. (2014). NK cells with KIR2DS2 immunogenotype have a functional activation advantage to efficiently kill glioblastoma and prolong animal survival. (ekstern lenke)
• Yang, Ning; Huang, Bin; Tsinkalovsky, Oleg et al. (2014). A novel GFP nude rat model to investigate tumor-stroma interactions. (ekstern lenke)
• Dodoo, Ernest; Huffmann, Beate; Peredo, Inti et al. (2014). Increased Survival Using Delayed Gamma Knife Radiosurgery for Recurrent High-Grade Glioma: A Feasibility Study. (ekstern lenke)
• Skeie, Bente Sandvei; Wang, Jian; Dodoo, Ernest et al. (2013). Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a Human GBM Xenograft Model. (ekstern lenke)
• Kmiecik, Justyna; Poli, Aurélie; Brons, Nicolas H.C. et al. (2013). Elevated CD3(+) and CD8(+) tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level. (ekstern lenke)
• Poli, Aurélie; Wang, Jian; Domingues, Olivia et al. (2013). Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival. (ekstern lenke)
• Jacobsen, Hege; Sleire, Linda; Wang, Jian et al. (2013). Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments. (ekstern lenke)
• Talasila, Krishna Mukharji; Soentgerath, Anke; Euskirchen, Philipp et al. (2013). EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. (ekstern lenke)
• Skeie, Bente Sandvei; Enger, Per Øyvind; Ganz, Jeremy Christopher et al. (2013). Gamma knife surgery of colorectal brain metastases: a high prescription dose of 25 Gy may improve growth control. (ekstern lenke)
• Willingham, Stephen B.; Volkmer, Jens-Peter; Gentles, Andrew J. et al. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. (ekstern lenke)
• Skeie, Bente; Enger, Per Øyvind; Brøgger, Jan C et al. (2012). Gamma knife surgery versus reoperation for recurrent glioblastoma multiforme. (ekstern lenke)
• Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian et al. (2012). Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. (ekstern lenke)
• Skeie, Bente; Skeie, Geir Olve; Enger, Per Øyvind et al. (2011). Gamma Knife Surgery in Brain Melanomas: Absence of Extracranial Metastases and Tumor Volume Strongest Indicators of Prolonged Survival. (ekstern lenke)
• Skeie, Bente; Skeie, Geir Olve; Enger, Per Øyvind et al. (2011). Gamma Knife Surgery of Colorectal Brain Metastases: A High Prescription Dose of 25 Gy May Improve Growth Control. (ekstern lenke)
• Yan, Tao; Skaftnesmo, Kai Ove; Leiss, Lina Wik et al. (2011). Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. (ekstern lenke)
• Svendsen, Agnete; Verhoeff, Joost JC; Immervoll, Heike et al. (2011). Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. (ekstern lenke)
• Wang, Jian; Svendsen, Agnete; Kmiecik, Justyna et al. (2011). Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma. (ekstern lenke)
• Goplen, Dorota; Bougnaud, Sébastien; Rajcevic, Uros et al. (2010). alpha B-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells. (ekstern lenke)
• Prestegarden, Lars; Svendsen, Agnete; Wang, Jian et al. (2010). Glioma cell populations grouped by different cell type markers drive brain tumor growth. (ekstern lenke)
• Enger, Per Øyvind; Skeie, Geir Olve; Thorsen, Frits Alan et al. (2010). Gamma knife surgery of meningiomas involving the cavernous sinus: long-term follow-up of 100 patients. (ekstern lenke)
• Wang, Jian; Miletic, Hrvoje; Sakariassen, Per Øystein et al. (2009). A reproducible brain tumour model established from human glioblastoma biopsies. (ekstern lenke)
• Johannessen, Tor-Christian Aase; Wang, Jian; Skaftnesmo, Kai Ove et al. (2009). Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. (ekstern lenke)
• Chekenya, Martha; Krakstad, Camilla; Svendsen, Agnete et al. (2008). The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. (ekstern lenke)
• Niclou, Simone P; Danzeisen, Claude; Eikesdal, Hans Petter et al. (2008). A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. (ekstern lenke)
• Thorsen, Frits Alan; Jirak, Daniel; Wang, Jian et al. (2008). Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. (ekstern lenke)
• Wang, Jian; Sakariassen, Per Øystein; Tsinkalovsky, Oleg et al. (2008). CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. (ekstern lenke)
• Thorsen, Frits Alan; Enger, Per Øyvind; Wang, Jian et al. (2007). Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. (ekstern lenke)
• Huszthy, Peter Csaba; Brekken, Christian; Pedersen, Tina Bugge et al. (2006). Antitumor efficacy improved by local delivery of species-specific endostatin. (ekstern lenke)
• Brekke, C; Brekke, Cecilie; Lundervold, Arvid et al. (2006). NG2 expression regulates vascular morphology and function in human brain tumours. (ekstern lenke)
• Sakariassen, Per Øystein; Prestegarden, Lars; Wang, Jian et al. (2006). Angiogenesis-independent tumor growth mediated by stem-like cancer cells. (ekstern lenke)
• Goplen, Dorota; Wang, Jian; Enger, Per Øyvind et al. (2006). Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. (ekstern lenke)
• Sundlisæter, Eirik; Wang, Jian; Sakariassen, Per Øystein et al. (2006). Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. (ekstern lenke)
• Brekke, Cecilie; Lundervold, Arvid; Enger, Per Øyvind et al. (2005). NG2 expression regulates vascular morphology and function in human brain tumours. (ekstern lenke)
• Chekenya, M; Chekenya, M; Hjelstuen, Mari H. et al. (2002). NG2 proteoglycan promotes angiogenesis-dependent tumor growth in the central nervous system by sequestering angiostatin. (ekstern lenke)
• Read, Tracy-Ann; Read, Tracy-Ann; Sorensen, DR et al. (2001). Local endostatin treatment of gliomas administered by microencapsulated producer cells. (ekstern lenke)

Poster

• Strømsnes, Torbjørn Austveg; BEHBAHANI, MAZIAR; Skeie, Geir Olve et al. (2021). Long term results following Repeat Gamma Knife Surgery for Incompletely obliterated Arteriovenous Malformations after the first Gamma Knife treatment. (ekstern lenke)
• Rahman, Mohummad Aminur; Leiss, Lina Wik; Lellahi, Seyed Mohammad et al. (2015). The transcription factor POU3F2 is expressed in human gliomas and promotes tumorigenesis in vivo. (ekstern lenke)
• Gjerde, Christiane Helgestad; Mutlu, Ercan; Leiss, Lina Wik et al. (2015). FGFR4 is expressed in the tumor and stromal compartments of human gliomas of all grades and histologies.. (ekstern lenke)
• Rahman, Mohummad Aminur; Leiss, Lina Wik; Lellahi, Seyed Mohammad et al. (2014). The transcription factor POU3f2 uniformly express in human gliomas and promotes tumorigenesis and overall growth rate in vivo. (ekstern lenke)
• Thuen, Marte; Wang, Jien; Enger, Per Øyvind et al. (2011). Therapeutic Targeting of NG2 Proteoglycan with MAb & Pre-Armed NK Cells in Human GMB Evaluated with Dynamic Enhanced & Diffusion Weighted MRI in Rats. (ekstern lenke)
• Johannessen, Tor-Christian Aase; Wang, Jian; Skaftnesmo, Kai Ove et al. (2009). Highly infiltrative brain tumors show reduced chemosensitivity associated with a stem cell-like phenotype. (ekstern lenke)
• Brekken, Christian; Brekke, Cecilie; Brekke, Cecilie et al. (2003). NG2 receptor status modifies human glioblastoma development: Assessment by MRI. (ekstern lenke)
• Brekken, Christian; Brekke, Cecilie; Brekke, Cecilie et al. (2003). Phenotyping by MRI: NG2 Receptor Status Modifies Human Glioblastoma Development. (ekstern lenke)
• Brekken, Christian; Enger, Per Øyvind; Enger, Per Øyvind et al. (2002). Endostatin gene trandsuction of glioma cells modifies brain tumor development: Assessment by MRI. (ekstern lenke)

Mastergradsoppgave

• Thorkildsen, Evy Marie; Enger, Per Øyvind; Sarowar, Shahin (2019). Sulfasalazine analogues to overcome radioresistance in cancer. (ekstern lenke)
• Mutlu, Ercan; Enger, Per Øyvind (2015). Tumour-associated glial cells promote the Growth of GBM xenografts. (ekstern lenke)
• Lellahi, Seyed Mohammad; Rahman, Mohummad Aminur; Enger, Per Øyvind (2014). POU3f2 in human gliomas - Expression pattern and functional role. (ekstern lenke)
• Enger, Per Øyvind; Sleire, Linda; Leiss, Lina Wik (2011). Impact of hypoxia on the expression of cell line markers and behavior of cultured glioma cell lines. (ekstern lenke)
• Johannessen, Mireille Kayitesi; Enger, Per Øyvind (2011). Growth of glioblastoma xenografts in the brains of NOD/SCID mice following administration of a demyelinating agent. (ekstern lenke)
• Andersen, Synne Marte; Enger, Per Øyvind (2010). Aquaporin 1 and Aquaporin 4 in Glioblastoma Multiforme. (ekstern lenke)
• Kroondijk, Liesbeth; Enger, Per Øyvind (2008). Involvement of E2F5 in brain tumour progression. (ekstern lenke)

Faglig foredrag

• Cirillo, Davide; Adamsen, Tom Christian Holm; Enger, Per Øyvind et al. (2018). Synthesis of targeting molecules as tracers for PET and anticancer pro-drugs: investigation of tumor drug distribution. (ekstern lenke)
• Cirillo, Davide; Sarowar, Shahin; Adamsen, Tom Christian Holm et al. (2018). Synthesis of targeting molecules as tracers for PET and anticancer pro-drugs: investigation of tumor drug distribution. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Sleire, Linda; Førde-Tislevoll, Hilde Elise; Netland, Inger Anne et al. (2017). Drug repurposing in cancer. (ekstern lenke)
• Prestegarden, Lars; Enger, Per Øyvind (2010). Cancer stem cells in the central nervous system - a critical review. (ekstern lenke)
• Sundlisæter, Eirik; Dicko, Aly; Sakariassen, Per Øystein et al. (2007). Lymphangiogenesis in colorectal cancer - Prognostic and therapeutic aspects. (ekstern lenke)

Doktorgradsavhandling

• Netland, Inger Anne; Enger, Per Øyvind (2015). Targeting survival signalling pathways in glioblastoma. Preclinical studies of sulfasalazine, dactolisib and buparlisib. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin