Vitenskapelig oversiktsartikkel/review

• Mukherjee, Sayani; Skrede, Silje; Fernø, Johan (2025). The hypothalamus as a therapeutic target: Towards novel approaches for managing antipsychotic-induced weight gain. (ekstern lenke)
• Tyssedal, Malene Kalsnes; Johnsen, Erik; Brønstad, Aurora Margrethe et al. (2023). Dog-assisted interventions for adults diagnosed with schizophrenia and related disorders: a systematic review. (ekstern lenke)
• Mukherjee, Sayani; Skrede, Silje; Haugstøyl, Martha et al. (2023). Peripheral and central macrophages in obesity. (ekstern lenke)
• Mukherjee, Sayani; Skrede, Silje; Milbank, Edward et al. (2021). Understanding the Effects of Antipsychotics on Appetite Control. (ekstern lenke)
• Kroken, Rune; Løberg, Else-Marie; Drønen, Tore et al. (2014). A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation. (ekstern lenke)

Vitenskapelig artikkel

• Serkland, Trond Trætteberg; Skrede, Silje; Hallin, Erik Ingmar et al. (2025). Pharmacokinetic-pharmacodynamic modelling in a clinical pilot study of rituximab in multiple sclerosis: Towards personalized dosing interval. (ekstern lenke)
• Ratke, Ieva; Torsvik, Anja; Bartz-Johannessen, Christoffer et al. (2025). Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort. (ekstern lenke)
• Horska, Katerina; Kucera, Jan; Drazanova, Eva et al. (2024). Potent synergistic effects of dulaglutide and food restriction in prevention of olanzapine-induced metabolic adverse effects in a rodent model. (ekstern lenke)
• Hoprekstad, Gunnhild Eldhuset; Skrede, Silje; Bartz-Johannessen, Christoffer et al. (2024). Association between cytokines and suicidality in patients with psychosis: A multicentre longitudinal analysis. (ekstern lenke)
• Skrede, Silje; Bogavac-Stanojević, Nataša; Dreesen, Erwin et al. (2024). Therapeutic drug monitoring of monoclonal antibodies in chronic inflammatory diseases: A snapshot of laboratories and applications across Europe. (ekstern lenke)
• Horska, Katerina; Skrede, Silje; Kucera, Jan et al. (2024). Olanzapine, but not haloperidol, exerts pronounced acute metabolic effects in the methylazoxymethanol rat model. (ekstern lenke)
• Torgauten, Hilde Marie; Onyango, Therese Bredholt; Ljostveit, Sonja et al. (2024). Hospitalisations and humoral COVID-19 vaccine response in vaccinated rituximab-treated multiple sclerosis patients. (ekstern lenke)
• Førde, Jan-Lukas; Alhourani, Abdelnour; Carey, Tian et al. (2024). Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation. (ekstern lenke)
• Hallin, Erik Ingmar; Serkland, Trond Trætteberg; Bjånes, Tormod Karlsen et al. (2024). High-throughput, low-cost quantification of 11 therapeutic antibodies using caprylic acid precipitation and LC-MS/MS. (ekstern lenke)
• Førde, Jan-Lukas; Herfindal, Lars; Myhr, Kjell-Morten et al. (2023). Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro. (ekstern lenke)
• Hoprekstad, Gunnhild Eldhuset; Kjelby, Eirik; Gjestad, Rolf et al. (2023). Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study. (ekstern lenke)
• Horska, Katerina; Ruda-Kucerova, Jana; Skrede, Silje (2022). GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?. (ekstern lenke)
• Hay, Anne Oldeide; Trones, Roger; Herfindal, Lars et al. (2022). Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. (ekstern lenke)
• Hallin, Erik Ingmar; Serkland, Trond Trætteberg; Myhr, Kjell-Morten et al. (2022). Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry. (ekstern lenke)
• Skrede, Silje; Berg, Jon Andsnes; FOSSAN, KJELL OVE et al. (2021). Illicit substances detected through high-resolution MS analysis in urine samples are associated with greater symptom burden in patients with psychosis. (ekstern lenke)
• Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø et al. (2021). Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness. (ekstern lenke)
• Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie et al. (2020). Amisulpride, aripiprazole, and olanzapine in patients with schizophrenia-spectrum disorders (BeSt InTro): a pragmatic, rater-blind, semi-randomised trial. (ekstern lenke)
• Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn et al. (2019). Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study. (ekstern lenke)
• Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even et al. (2019). One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects. (ekstern lenke)
• Serkland, Trond T.; Schjøtt, Jan; Berg, Jon Andsnes et al. (2019). Short communication: Distribution of psychotropic drugs into lipoproteins. (ekstern lenke)
• Gjerde, Priyanthi Borgen; Dieset, Ingrid; Simonsen, Carmen Elisabeth et al. (2018). Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis. (ekstern lenke)
• Skrede, Silje; Gonzalez-Garcia, Ismael; Martins, Luis et al. (2017). Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. (ekstern lenke)
• Marti, Andrea Rørvik; Patil, Sudarshan; Mrdalj, Jelena et al. (2017). No escaping the rat race: simulated night shift work alters the time-of-day variation in BMAL1 translational activity in the prefrontal cortex. (ekstern lenke)
• Ersland, Kari Merete; Skrede, Silje; Stansberg, Christine et al. (2017). Subchronic olanzapine exposure leads to increased expression of myelination-related genes in rat fronto-medial cortex. (ekstern lenke)
• Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt et al. (2016). Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial. (ekstern lenke)
• Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine et al. (2016). Implication of NOTCH1 Gene in Susceptibility to Anxiety and Depression among Sexual Abuse Victims. (ekstern lenke)
• Marti, Andrea Rørvik; Meerlo, Peter; Grønli, Janne et al. (2016). Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shiftwork: A rat model. (ekstern lenke)
• Grønli, Janne; Meerlo, Peter; Pedersen, Torhild et al. (2016). A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. (ekstern lenke)
• Steen, Vidar Martin; Skrede, Silje; Polushina, Tatiana et al. (2016). Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. (ekstern lenke)
• Ersland, Kari Merete; Skrede, Silje; Røst, Therese Halvorsen et al. (2015). Antipsychotic-induced metabolic effects in the female rat: Direct comparison between long-acting injections of risperidone and olanzapine. (ekstern lenke)
• Reikvam, Håkon; Brenner, Annette; Hagen, Karen Marie et al. (2015). The cytokine-mediated crosstalk between primary human acute myeloid cells and mesenchymal stem cells alters the local cytokine network and the global gene expression profile of the mesenchymal cells. (ekstern lenke)
• Skrede, Silje; Tvete, Ingunn Fride; Tanum, Lars et al. (2015). Incident users of antipsychotic agents and future use of cholesterol-lowering drugs: An observational, pharmacoepidemiologic study. (ekstern lenke)
• Fernø, Johan; Ersland, Kari Merete; Duus, Inger Hødnebø et al. (2015). Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. (ekstern lenke)
• Reikvam, Håkon; Tamburini, Jerome; Skrede, Silje et al. (2014). Antileukaemic effect of PI3K-mTOR inhibitors in acute myeloid leukaemia-gene expression profiles reveal CDC25B expression as determinate of pharmacological effect. (ekstern lenke)
• Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt et al. (2014). Blocking blue light during mania - markedly increased regularity of sleep and rapid improvement of symptoms: A case report. (ekstern lenke)
• Skrede, Silje; Martins, Luis; Berge, Rolf Kristian et al. (2014). Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. (ekstern lenke)
• Steen, Vidar Martin; Nepal, Chirag; Ersland, Kari Merete et al. (2013). Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1. (ekstern lenke)
• Skrede, Silje; Steen, Vidar Martin; Fernø, Johan (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (ekstern lenke)
• Jassim, Goran; Skrede, Silje; Vázquez, Maria Jesús et al. (2012). Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. (ekstern lenke)
• Skrede, Silje; Fernø, Johan; Vázquez, Maria Jesús et al. (2012). Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. (ekstern lenke)
• Skrede, Silje; Fernø, Johan; Bjørndal, Bodil et al. (2012). Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. (ekstern lenke)
• Fernø, Johan; Varela, Luis; Skrede, Silje et al. (2011). Olanzapine-induced hyperphagia and weight gain associate with crexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. (ekstern lenke)
• Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2011). Lipogenic effects of psychotropic drugs: focus on the SREBP system. (ekstern lenke)
• Vik-Mo, Audun Osland; Fernø, Johan; Skrede, Silje et al. (2009). Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. (ekstern lenke)
• Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran et al. (2009). Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. (ekstern lenke)
• Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2006). Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs. (ekstern lenke)
• Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland et al. (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. (ekstern lenke)
• Skrede, Silje; Holmsen, Holm A (2003). Schizofreni og membranpatologi - har antipsykotika en rolle i "membranteorien"?. (ekstern lenke)

Poster

• Hallin, Erik Ingmar; Bjånes, Tormod Karlsen; Serkland, Trond Trætteberg et al. (2024). A high-throughput, low-cost LC-MS/MS panel for precision analysis of therapeutic antibodies. (ekstern lenke)
• Hallin, Erik Ingmar; Serkland, Trond Trætteberg; FOSSAN, KJELL OVE et al. (2024). A rapid, automatable multiplex LC-MS/MS protocol for concomitant analysis of therapeutic antibodies. (ekstern lenke)
• Berg, Jon Andsnes; Skrede, Silje; Hansen, Joakim et al. (2023). "Virtual Pharma" - a digital tool for visualizing pharmacokinetics and pharmacodynamics. (ekstern lenke)
• Serkland, Trond Trætteberg; Hallin, Erik Ingmar; Myhr, Kjell-Morten et al. (2022). LC-MS/MS quantification of ocrelizumab in the treatment of multiple sclerosis. (ekstern lenke)
• Serkland, Trond Trætteberg; Hallin, Erik Ingmar; FOSSAN, KJELL OVE et al. (2021). Establishing an LC-MS/MS method as a tool in a TDM approach when treating multiple sclerosis with monoclonal antibodies. (ekstern lenke)
• Grønli, Janne; Marti, Andrea Rørvik; waslander, jorrit et al. (2018). Extended photoperiod alters sleep and expression of synaptic plasticity-associated genes. The impact of blue-enriched light.. (ekstern lenke)
• Marti, Andrea Rørvik; Skrede, Silje; Mrdalj, Jelena et al. (2018). Extending the photoperiod impacts circadian rhythmicity and gene expression in prefrontal cortex and retina- Impact of exposure to blue-enriched light.. (ekstern lenke)
• Marti, Andrea Rørvik; waslander, jorrit; Skrede, Silje et al. (2018). Extended photoperiod alters circadian rhythmicity and expression of neuroplasticity markers. The impact of blue-enriched light.. (ekstern lenke)
• Kroken, Rune Andreas; Løberg, Else-Marie; Gjestad, Rolf et al. (2017). The influence of 3 weeks of antipsychotic treatment on cell adhesion molecules in drug naive patients with schizophrenia spectrum disorder. (ekstern lenke)

Mastergradsoppgave

• Oma, Anna Kristina Fredheim; Skrede, Silje; Röblitz, Susanna et al. (2024). Pharmacokinetic models in personalized dosing of vancomycin. (ekstern lenke)
• Skrede, Silje; Sivertsen, Anette; Herfindal, Lars (2023). Zebrafish Larvae as a Model Organism to Study Biotransformation. (ekstern lenke)
• Sætrang, Maren Sukke; Herfindal, Lars; Skrede, Silje (2022). Electromembrane extraction of immunosuppressants. (ekstern lenke)
• Hay, Anne Oldeide; Skrede, Silje; Herfindal, Lars (2021). Electromembrane extraction of methotrexate and its metabolites. (ekstern lenke)
• Herfindal, Lars; Stipic, Martina; Serkland, Trond T. et al. (2020). Drug transport in blood: Lipoproteins as transporters of psychotropic drugs. (ekstern lenke)
• Skrede, Silje; Bakken, Vibeke Løvås; Ersland, Kari Merete et al. (2018). Gene Expression Changes in Rat Brain Following Long-term Antipsychotic Drug Exposure. (ekstern lenke)

Faglig foredrag

• Skrede, Silje (2024). Presisjonsmedisin i psykiatrien - håp eller hype?. (ekstern lenke)
• Skrede, Silje (2024). Therapeutic drug monitoring of biologics: the role of analytics. (ekstern lenke)
• Skrede, Silje (2022). Elektromembran-ekstraksjon i Bergen. (ekstern lenke)

Vitenskapelig foredrag

• Skrede, Silje (2023). TDM for mAbs - prospects based on progress of analytical methods. (ekstern lenke)
• Serkland, Trond Trætteberg; Hallin, Erik Ingmar; Myhr, Kjell-Morten et al. (2022). Rituximab in the treatment of multiple sclerosis: A pharmacokinetic-pharmacodynamic model. (ekstern lenke)
• Marti, Andrea Rørvik; Mrdalj, Jelena; Skrede, Silje et al. (2016). Simulated night work alters clock gene expression in central and peripheral tissue in rats.. (ekstern lenke)
• Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine et al. (2016). Implication of NOTCH1 Gene in Comorbid Anxiety and Depression Symptoms in a Sample of Sexual Abuse Victims.. (ekstern lenke)
• Mrdalj, Jelena; Pedersen, Torhild Thue; Marti, Andrea Rørvik et al. (2015). Night work - disturbances in sleep and circadian rhythm parameters. An animal model.. (ekstern lenke)

Doktorgradsavhandling

• Gjerde, Priyanthi Borgen; Steen, Vidar Martin; Melle, Ingrid et al. (2020). Lipid effects during antipsychotic drug treatment and their relevance for clinical outcomes. (ekstern lenke)
• Skrede, Silje (2012). Developing a rodent model for antipsychotic-induced metabolic adverse effects. (ekstern lenke)

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• Ersland, Kari Merete; Skrede, Silje (2018). Virker antipsykotika gjennom stimulering av myelinproduksjon i hjernen?. (ekstern lenke)
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Rapport

• Tvete, Ingunn Fride; Bramness, Jørgen Gustav; Skrede, Silje et al. (2015). Nye brukere av antipsykotika og utvikling av diabetes mellitus. (ekstern lenke)

Leder

• Skrede, Silje; Fernø, Johan; Steen, Vidar Martin (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (ekstern lenke)

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