Research
The research of Ivar Hordvik is focused on components of the adaptive immune system in fish. A long term goal is to broaden the spectrum of well characterized molecules and develop molecular tools that can be used to study immune responses during experiments with vaccines and pathogens in fish.
After teleost fish made a separate branch on the phylogenetic tree significant differences have been introduced between fish and mammals, both with respect to primary sequence of corresponding molecules, and the introduction of new molecules by gene duplications. An example of this is the evolution of the immunoglobulins: Whereas IgM has been evolutionarily stable and maintained the primordial structure in all jawed vertebrates the IgD gene has been evolutionarily labile and has been subjected to many internal duplications and deletions. A newly discovered gene, encoding an isotype named IgT/IgZ appears to be specific for teleost fish. On the other hand, IgG, IgE, and IgA are isotypes present in mammals, but not in fish.
Several findings the last years have shown that studies of the immune system in fish still offers surprises. It is plausible to assume that improved knowledge on the function and ontogeny of immune components in fish will aid experimental design of future vaccination trials and interpretation of results. Delivery of vaccines across mucosal surfaces of fish would obviously be an advantage and boost the profitability of the aquaculture industry. Development of new reagents for identification of immune cells and for monitoring immune responses is also an issue which has been addressed by vaccine companies as well as many researchers.
Publications
Academic article
- Bjørgen, Håvard; Barac, Fran; Fjelldal, Per Gunnar et al. (2024). Organisation of the Atlantic salmon (Salmo salar) thymus and its content of Ig-expressing cells. (external link)
- Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf et al. (2024). The ontogeny of lymphoid organs and IgM<sup>+</sup> B-cells in ballan wrasse (Labrus bergylta) reveals a potential site for extrarenal B-cell lymphopoiesis: The pancreas. (external link)
- Etayo, Angela; Bjørgen, Håvard; Hordvik, Ivar et al. (2024). Possible transport routes of IgM to the gut of teleost fish. (external link)
- Etayo, Angela; Lie, Kai Kristoffer; Bjelland, Reidun Marie et al. (2023). The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled. (external link)
- Castro, Pedro Luis; Barac, Fran; Hansen, Tom Johnny et al. (2023). The Distribution of IgT mRNA<sup>+</sup> Cells in the Gut of the Atlantic Salmon (Salmo salar L.). (external link)
- Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf et al. (2022). The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates. (external link)
- Bilal, Sumaira; Lie, Kai Kristoffer; Dalum, Alf Seljenes et al. (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. (external link)
- Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar et al. (2019). A teleost structural analogue to the avian bursa of Fabricius. (external link)
- Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind et al. (2019). Intramuscular vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) induces inflammatory reactions and local immunoglobulin M production at the vaccine administration site. (external link)
- Bjørgen, Håvard; Koppang, Erling Olaf; Gunnes, Gjermund et al. (2018). Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation. (external link)
- Bilal, Sumaira; Lie, Kai Kristoffer; Sæle, Øystein et al. (2018). T cell receptor alpha chain genes in the teleost Ballan wrasse (Labrus bergylta) are subjected to somatic hypermutation. (external link)
- Aas, Ida Bergva; Austbø, Lars; Falk, Knut et al. (2017). The interbranchial lymphoid tissue likely contributes to immune tolerance and defense in the gills of Atlantic salmon. (external link)
- Erkinharju, Toni; Dalmo, Roy Ambli; Vågsnes, Øyvind et al. (2017). Vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) at a low temperature leads to a low antibody response against Aeromonas salmonicida. (external link)
- Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind et al. (2017). Studies on the antibody response and side effects after intramuscular and intraperitoneal injection of Atlantic lumpfish (Cyclopterus lumpus L.) with different oil-based vaccines. (external link)
- Dalum, Alf Seljenes; Tangen, Randi; Falk, Knut et al. (2016). Coronary changes in the Atlantic salmon Salmo salar L: characterization and impact of dietary fatty acid compositions. (external link)
- Bilal, Sumaira; Lie, Kai Kristoffer; Karlsen, Odd Andre et al. (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). (external link)
- Hordvik, Ivar (2015). Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar. (external link)
- Dalum, Alf Seljenes; Austbø, Lars; Bjørgen, Håvard et al. (2015). The interbranchial lymphoid tissue of Atlantic Salmon (Salmo salar L) extends as a diffuse mucosal lymphoid tissue throughout the trailing edge of the gill filament. (external link)
- Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie et al. (2014). Transcriptional characterization of the T cell population within the salmonid interbranchial lymphoid tissue. (external link)
- Løkka, Guro; Austbø, Lars; Falk, Knut et al. (2014). Immune parameters in the intestine of wild and reared unvaccinated and vaccinated Atlantic salmon (Salmo salar L.). (external link)
- Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten et al. (2013). Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD). (external link)
- Kamil, Atif; Raae, Arnt Johan; Fjelldal, Per Gunnar et al. (2013). Comparative analysis of IgM sub-variants in salmonid fish and identification of a residue in mu 3 which is essential for MAb4C10 reactivity. (external link)
- Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten et al. (2012). Cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI). (external link)
- Larsen, Hilde; Austbø, Lars; Mørkøre, Turid et al. (2012). Pigment-producing granulomatous myopathy in Atlantic salmon: A novel inflammatory response. (external link)
- Wiik-Nielsen, Jannicke; Løvoll, Marie Therese; Fritsvold, Camilla et al. (2012). Characterization of myocardial lesions associated with cardiomyopathy syndrome in Atlantic salmon, Salmo salar L., using laser capture microdissection. (external link)
- Tadiso, Tariku Markos; Lie, Kai Kristoffer; Hordvik, Ivar (2011). Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues. (external link)
- Tadiso, Tariku Markos; Sharma, Animesh; Hordvik, Ivar (2011). Analysis of polymeric immunoglobulin receptor- and CD300-like molecules from Atlantic salmon. (external link)
- Tadiso, Tariku Markos; Krasnov, Aleksei; Skugor, Stanko et al. (2011). Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition. (external link)
- Kamil, Atif; Falk, Knut; Sharma, Animesh et al. (2011). A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. (external link)
- Koppang, Erling Olaf; Fischer, Uwe; Moore, Lindsey et al. (2010). Salmonid T cells assemble in the thymus, spleen and in novel interbranchial lymphoid tissue. (external link)
- Moore, Lindsey; Dijkstra, J.M; Koppang, Erling Olaf et al. (2009). CD4 homologues in Atlantic salmon. (external link)
- Moore, Lindsey; Dijkstra, Johannes Martinus ; Koppang, Erling Olaf et al. (2009). CD4 homologues in Atlantic salmon. (external link)
- Øvergård, Aina-Cathrine; Hordvik, Ivar; Nerland, Audun H. et al. (2009). Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. (external link)
- Haugarvoll, Erlend; Bjerkås, Inge; Nowak, BF et al. (2008). Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. (external link)
- Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf et al. (2008). Characterization of the CD3f, CD3cd and CD3e subunits of the T cell receptor complex in Atlantic salmon. (external link)
- Haugarvoll, Erlend; Bjerkås, Inge; Nowak, Barbara F. et al. (2008). Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. (external link)
- Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf et al. (2008). Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon. (external link)
- Morrison, RN; Koppang, Erling Olaf; Hordvik, Ivar et al. (2006). MHC class ll+ cells in the gills of Atlantic salmon ( Salmo salar L.) affected by amoebic gill disease. (external link)
- Morrison, Richard N.; Koppang, Erling Olaf; Hordvik, Ivar et al. (2006). MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease. (external link)
- Hevrøy, Ernst Morten; Jordal, Ann-Elise Olderbakk; Hordvik, Ivar et al. (2006). Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar. (external link)
- Dijkstra, Johannes Martinus ; Somamoto, Tomonori; Moore, Lindsey et al. (2006). Identification and characterization of a second CD4-like gene in teleost fish. (external link)
- Fischer, Uwe; Dijkstra, J.M; Kollner, B et al. (2005). The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). (external link)
- Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar et al. (2005). Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. (external link)
- Olsvik, Pål A.; Lie, Kai Kristoffer; Olderbakk Jordal, Anne-Lise et al. (2005). Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon. (external link)
- Van Do, Thien; Elsayed, Said; Florvaag, Erik et al. (2005). Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish. (external link)
- Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar et al. (2005). Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. (external link)
- Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (2005). Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M. (external link)
- Moore, LJ; Somamoto, T; Lie, KK et al. (2005). Characterisation of salmon and trout CD8 alpha and CD8 beta. (external link)
- Fischer, Uwe; Dijkstra, Johannes Martinus ; Köllner, Bernd et al. (2005). The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). (external link)
- Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar et al. (2004). Granulomatous uveitis associated with vaccination in the Atlantic salmon. (external link)
- Hordvik, Ivar; Torvund, Jannicke; Moore, Lindsey et al. (2004). Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon. (external link)
- Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar et al. (2004). Granulomatous uveitis associated with vaccination in the Atlantic salmon. (external link)
- Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge et al. (2003). Production of rabbit antisera against recombinant MHC class II B chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). (external link)
- Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge et al. (2003). Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye. (external link)
- Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge et al. (2003). Vaccination Induces Major Histocompatibility Complex Class II Expression in the Atlantic Salmon Eye. (external link)
- Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge et al. (2003). Production of rabbit antisera against recombinant MHC class II beta chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). (external link)
- Hordvik, Ivar; Koppang, Erling Olaf (2002). Karakterisering av immungener hos fisk. Litt historikk, status og fremtidsutsikter. (external link)
- Hordvik, Ivar (2002). Identification of a novel immunoglobulin δ transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut. (external link)
- Hordvik, Ivar; Berven, Frode; Solem, Stein Tore et al. (2002). Analysis of two IgM isotypes in Atlantic salmon and brown trout. (external link)
- Solem, Stein T.; Hordvik, Ivar; Killie, Jan-Eirik A. et al. (2001). Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci. (external link)
- Hatten, Frode; Fredriksen, Åse; Hordvik, Ivar et al. (2001). Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus. (external link)
- Do, Thien van; Hordvik, Ivar; Endresen, Curt et al. (1999). Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). (external link)
- Krossøy, Bjørn; Hordvik, Ivar; Nilsen, Frank et al. (1999). The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae. (external link)
- Hordvik, Ivar; Thevarajan, J.; Samdal, I. et al. (1999). Molecular cloning and phylogenetic analysis of the Atlantic salmon Immunoglobulin D gene. (external link)
- Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (1999). Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). (external link)
- Nilsen, Frank; Endresen, Curt; Hordvik, Ivar (1998). Molecular phylogeny of mcrosoridians with particular reference to species that infect the muscles of fish. (external link)
- Hordvik, Ivar (1998). The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes. (external link)
- Hordvik, Ivar; Lindstrøm, Christian De Vries; Voie, Ann-Mari et al. (1997). Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar. (external link)
- Elsayed, Said; Lindstrøm, c.d-v; Van Do, Thien et al. (1996). Cloning of two distinct cDNA encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). (external link)
- Hordvik, Ivar; Jacob, Anne Lilybert J.; Charlemagne, Jacques et al. (1996). Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar). (external link)
- Nylund, Are; Hordvik, Ivar; Endresen, Curt (1996). Avl og sykdomsresistens. (external link)
- Lindstrøm, Christian De Vries; Van Do, Thien; Hordvik, Ivar et al. (1996). Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). (external link)
- Lie, Ø.; Slettan, A.; Lingaas, F. et al. (1994). Haploid gynogenesis. A powerful strategy for linkage analysis in fish. (external link)
- Hordvik, Ivar (1994). Immune genes of the Atlantic salmon. Application of modern genetic techniques to the study of antibodies and MHC antigens from Atlantic salmon. (external link)
- Grimholt, U.; Hordvik, Ivar; Fosse, Vivian Jacobsen et al. (1993). Molecular cloning of major histocompability complex class I cDNAs from Atlantic salmon (Salmo salar). (external link)
- Hordvik, Ivar; Grimholt, Unni; Fosse, Viggo M. et al. (1993). Cloning and sequence analysis of cDNAs encoding the MHC class II beta chain in Atlantic salmon (Salmo salar). (external link)
- Molven, Anders; Hordvik, Ivar; Njølstad, Pål Rasmus et al. (1992). The zebrafish homeobox gene Hox(zf-114): primary structure, expression pattern and evolutionary aspects. (external link)
- Hordvik, Ivar; Voie, A. M.; Glette, J. et al. (1992). Cloning and sequence analysis of two isotopic IgM heavy chain genes from Atlantic salmon, Salmo salar L. (external link)
Academic literature review
Poster
- Bjørgen, Håvard; Hordvik, Ivar; Koppang, Erling Olaf (2019). Inflammatory changes and melanization in the Atlantic salmon (Salmo salar) targeted by in situ hybridization. (external link)
- Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind Brune et al. (2019). Intramuscular injection of an oil-based vaccine in Atlantic lumpfish induces local IgM production.. (external link)
- Moldal, Torfinn; Koppang, Erling Olaf; Kaldhusdal, Magne et al. (2011). Intestinal epithelial dysplasia and adenocarcinoma in salmonids is associated with inflammation. (external link)
- Yousaf, Muhammad Naveed; Powell, Mark; Koppang, Erling Olaf et al. (2011). Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry.. (external link)
- Yousaf, Muhammed; Powell, Mark Darryn; Koppang, Erling Olaf et al. (2010). Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry. (external link)
- Bakke McKellep, Anne Marie; Koppang, Erling Olaf; Hordvik, Ivar et al. (2003). Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.). (external link)
- Bakke McKellep, Anne Marie; Koppang, Erling Olaf; Hordvik, Ivar et al. (2003). Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.). (external link)
- Hordvik, Ivar (2002). The immunoglobulin heavy chain gene loci in Atlantic salmon: Analysis of IgM subvariants related to ancestral tetraploidy and identification of a novel IgD transcript. (external link)
- Hordvik, Ivar (2002). Analyse av immunoglobulin D uttrykking hos laks. (external link)
Doctoral dissertation
- Bilal, Sumaira; Hordvik, Ivar; Karlsen, Odd Andre (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta). (external link)
- Hordvik, Ivar (1993). Immune genes of the Atlantic salmon. Cloning and sequence analyses of genes encoding the IgM heavy chain, the MHC class I alpha-chain and the MHC class II beta-chain. (external link)
Academic lecture
- Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar et al. (2019). Distribution of different populations of T cells and B cells in the interbranchial lymphoid tissue (ILT) of salmon. (external link)
- Bjørgen, Håvard; Haldorsen, Randi; Oaland, Øyvind et al. (2019). Characterization and development of focal red and melanised changes in the Atlantic salmon. (external link)
- Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind Brune et al. (2019). Intramuscular vaccination of Atlantic lumpfish induces inflammation and local IgM production.. (external link)
- Erkinharju, Toni; Lundberg, Martin Rønbeck; Isdal, Eivind et al. (2017). Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not? Emphasis on fish welfare and immune response . (external link)
- Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind et al. (2017). Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not?. (external link)
- Koppang, Erling Olaf; Kaldhusdal, Magne; Hordvik, Ivar et al. (2011). Tarmkreft hos laksefisk er assosiert med betennelse. (external link)
- Hordvik, Ivar; Lie, Kai K; Koppang, Erling Olaf (2003). Analysis of IgD expression in Atlantic salmon. (external link)
- Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge (2002). Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar). (external link)
- Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge (2002). Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar). (external link)
- Hordvik, Ivar (2001). Identification of IgD heavy chain RNA splice variants in Atlantic salmon, Salmo salar. (external link)
- Hordvik, Ivar (2001). Analyse av immunoglobulin D uttrykking hos laks. (external link)
- Hordvik, Ivar; Hatten, Frode; Solem, Stein Tore et al. (2000). IgM and IgD heavy chain subvariants in Atlantic salmon and brown trout, related to ancestral tetraploidy. (external link)
- Grimholt, Unni; Hordvik, Ivar; Olsaker, Ingrid et al. (1993). MHC polymorphism in Atlantic salmon. (external link)
- Hordvik, Ivar; Voie, Ann Mari; Lindstrøm, Christian De Vries et al. (1993). Two isotypic IgM heavy chain genes of the Atlantic salmon. (external link)
Popular scientific article
Abstract
- Løkka, Guro; Austbø, Lars; Falk, Knut et al. (2013). Expression of immune related genes in the Atlantic salmon intestine. (external link)
- Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie et al. (2013). The immunological function of the interbranchial lymphoid tissue (ILT). (external link)
- Hordvik, Ivar; Kamil, Atif; Bilal, Sumaira et al. (2013). Characterization of serum IgM in teleost fish, with emphasis on salmonids. (external link)
- Frøyse, Alf Lars Dalum; Thorsen, Jim; Austbø, Lars et al. (2013). Anatomy of the interbranchial lymphoid tissue (ILT) in salmonid fish. (external link)
Article in business/trade/industry journal
Reader opinion piece
Thesis at a second degree level
- Espedal, Per Gunnar; Pittman, Karin; Hordvik, Ivar (2007). Deteksjon av IgM-positive celler i blodutstryk fra kveite (Hippoglossus hippoglossus L.): in situ hybridisering med to typer prober. (external link)
- Samdal, Ingvild; Hordvik, Ivar; Szilvay, Anne Marie (2004). Expression of two fragments from the atlantic salmon major histocompability class 1α chain in E.coli, utilizing two different. (external link)
- Lie, Kai Kristoffer; Hordvik, Ivar (2004). Analyse av IgM- og IgD-genuttrykking i ulike vev hos atlantisk laks (Salmo salar L.). (external link)
Academic chapter/article/Conference paper
Feature article
- Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (1997). cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). (external link)
- Van, Dô; Hordvik, Ivar; Endresen, Curt et al. (1997). cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). (external link)
See a complete overview of publications in Cristin.
Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes
Author(s): Overgard, AC; Hordvik, I; Nerland, AH, et al.
Source: FISH & SHELLFISH IMMUNOLOGY Volume: 27 Issue: 6 Pages: 707-713 Published: 2009
CD4 homologues in Atlantic salmon
Author(s): Moore, LJ; Dijkstra, JM; Koppang, EO, et al.
Source: FISH & SHELLFISH IMMUNOLOGY Volume: 26 Issue: 1 Pages: 10-18 Published: 2009
Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon
Author(s): Haugarvoll, E; Bjerkas, I; Nowak, BF, et al.
Source: JOURNAL OF ANATOMY Volume: 213 Issue: 2 Pages: 202-209 Published: 2008
Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon
Author(s): Liu, Y; Moore, L; Koppang, EO, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY Volume: 32 Issue: 1 Pages: 26-35 Published: 2008
FABP3 and FABP10 in Atlantic salmon (Salmo salar L.) - General effects of dietary fatty acid composition and life cycle variations
Author(s): Jordal, AEO; Hordvik, I; Pelsers, M, et al.
Source: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY Volume: 145 Issue: 2 Pages: 147-158 Published: OCT 2006
Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar
Author(s): Hevroy, EM; Jordal, AEO; Hordvik, I, et al.
Source: AQUACULTURE Volume: 252 Issue: 2-4 Pages: 453-461 Published: MAR 10 2006
Identification and characterization of a second CD4-like gene in teleost fish
Author(s): Dijkstra, JM; Somamoto, T; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 43 Issue: 5 Pages: 410-419 Published: FEB 2006
MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease
Author(s): Morrison, RN; Koppang, EO; Hordvik, I, et al.
Source: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY Volume: 109 Issue: 3-4 Pages: 297-303 Published: FEB 15 2006
Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish
Author(s): Van Do, T; Elsayed, S; Florvaag, E, et al.
Source: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Volume: 116 Issue: 6 Pages: 1314-1320 Published: DEC 2005
Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon
Author(s): Olsvik, PA; Lie, KK; Jordal, AEO, et al.
Source: BMC MOLECULAR BIOLOGY Volume: 6 Article Number: 21 Published: NOV 17 2005
Characterisation of salmon and trout CD8 alpha and CD8 beta
Author(s): Moore, LJ; Somamoto, T; Lie, KK, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 42 Issue: 10 Pages: 1225-1234 Published: JUN 2005
Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 42 Issue: 3 Pages: 345-353 Published: FEB 2005
The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss)
Author(s): Fischer, U; Dijkstra, JM; Kollner, B, et al.
Source: FISH & SHELLFISH IMMUNOLOGY Volume: 18 Issue: 1 Pages: 49-60 Published: JAN 2005
Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: JOURNAL OF FISH DISEASES Volume: 28 Issue: 1 Pages: 13-22 Published: JAN 2005
Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon
Author(s): Hordvik, I; Torvund, J; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 41 Issue: 5 Pages: 553-559 Published: JUL 2004
Granulomatous uveitis associated with vaccination in the Atlantic salmon
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: VETERINARY PATHOLOGY Volume: 41 Issue: 2 Pages: 122-130 Published: MAR 2004
Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye
Author(s): Koppang, EO; Bjerkas, E; Bjerkas, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY Volume: 58 Issue: 1 Pages: 9-14 Published: JUL 2003
The major allergen (parvalbumin) of codfish is encoded by at least two isotypic genes: cDNA cloning, expression and antibody binding of the recombinant allergens
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 39 Issue: 10 Pages: 595-602 Published: JAN 2003
Analysis of two IgM isotypes in Atlantic salmon and brown trout
Author(s): Hordvik, I; Berven, FS; Solem, ST, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 39 Issue: 5-6 Pages: 313-321 Published: OCT 2002
Identification of a novel immunoglobulin delta transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut
Author(s): Hordvik, I
Source: MOLECULAR IMMUNOLOGY Volume: 39 Issue: 1-2 Pages: 85-91 Published: SEP 2002
Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci.
Author(s): Solem, ST; Hordvik, I; Killie, JEA, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY Volume: 25 Issue: 5-6 Pages: 403-417 Published: JUN-JUL 2001
Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus
Author(s): Hatten, F; Fredriksen, A; Hordvik, I, et al.
Source: FISH & SHELLFISH IMMUNOLOGY Volume: 11 Issue: 3 Pages: 257-268 Published: APR 2001
Expression and analysis of recombinant salmon parvalbumin, the major allergen in atlantic salmon (Salmo salar)
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY Volume: 50 Issue: 6 Pages: 619-625 Published: 1999
Molecular cloning and phylogenetic analysis of the Atlantic salmon immunoglobulin D gene
Author(s): Hordvik, I; Thevarajan, J; Samdal, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY Volume: 50 Issue: 2 Pages: 202-210 Published: AUG 1999
The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae
Author(s): Krossoy, B; Hordvik, I; Nilsen, F, et al.
Source: JOURNAL OF VIROLOGY Volume: 73 Issue: 3 Pages: 2136-2142 Published: MAR 1999
The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes
Author(s): Hordvik, I
Source: IMMUNOLOGICAL REVIEWS Volume: 166 Pages: 153-157 Published: DEC 1998
Molecular phylogeny of microsporidians with particular reference to species that infect the muscles of fish
Author(s): Nilsen, F; Endresen, C; Hordvik, I
Source: JOURNAL OF EUKARYOTIC MICROBIOLOGY Volume: 45 Issue: 5 Pages: 535-543 Published: SEP-OCT 1998
Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar
Author(s): Hordvik, I; Lindstrom, CD; Voie, AM, et al.
Source: MOLECULAR IMMUNOLOGY Volume: 34 Issue: 8-9 Pages: 631-639 Published: JUN 1997
Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar)
Author(s): Hordvik, I; Jacob, ALJ; Charlemagne, J, et al.
Source: IMMUNOGENETICS Volume: 45 Issue: 1 Pages: 9-14 Published: 1996
Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar)
Author(s): Lindstrom, CDV; VanDo, T; Hordvik, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY Volume: 44 Issue: 4 Pages: 335-344 Published: OCT 1996
Immune genes of the Atlantic salmon, Salmo salar L.: Application of modern molecular genetic techniques to the study of antibodies and major histocompatibility complex antigens
Author(s): Hordvik, I.
Source: Aquaculture and Fisheries Management Volume: 25 Issue: 1 Pages: 47-53 Published: 1994
Haploid gynogenesis: A powerful strategy for linkage analysis in fish
Author(s): Lie, O.; Slettan, A.; Lingaas, F., et al.
Source: Animal Biotechnology Volume: 5 Issue: 1 Pages: 33-45 Published: 1994
MOLECULAR-CLONING OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I CDNAS FROM ATLANTIC SALMON (SALMO-SALAR)
Author(s): GRIMHOLT, U; HORDVIK, I; FOSSE, VM, et al.
Source: IMMUNOGENETICS Volume: 37 Issue: 6 Pages: 469-473 Published: FEB 1993
CLONING AND SEQUENCE-ANALYSIS OF CDNAS ENCODING THE MHC CLASS-II BETA-CHAIN IN ATLANTIC SALMON (SALMO-SALAR)
Author(s): HORDVIK, I; GRIMHOLT, U; FOSSE, VM, et al.
Source: IMMUNOGENETICS Volume: 37 Issue: 6 Pages: 437-441 Published: FEB 1993
CLONING AND SEQUENCE-ANALYSIS OF 2 ISOTYPIC IGM HEAVY-CHAIN GENES FROM ATLANTIC SALMON, SALMO-SALAR L
Author(s): HORDVIK, I; VOIE, AM; GLETTE, J, et al.
Source: EUROPEAN JOURNAL OF IMMUNOLOGY Volume: 22 Issue: 11 Pages: 2957-2962 Published: NOV 1992