Research
Oddvar Oppegaard is senior physician at the Department of Infectious Diseases, Haukeland University Hospital and an assistant professor at the Department of Clinical Science, UoB. Important fields of research have been serious streptococcal infections with the main focus on bacterial virulence, resistance and pathogenesis. The work includes bioinformatic whole genome analysis, as well as genetic characterization and manipulation of bacterial strains in the laboratory. Oppegaard and the streptococcus research group at the University of Bergen and Haukeland University Hospital are currently participating in the PERMIT and PERAID projects (https://permedinfect.com/) funded by Nordforsk and the EU. These projects aim to promote research into personalized medicine (PM) in serious infectious diseases, especially life-threatening necrotizing soft tissue infections (NSTI) and sepsis.
Publications
Academic article
- Alnæs, Marie Bjørbak; Guttormsen, Anne Berit; Terreehorst, Ingrid et al. (2025). Norwegian Anaesthesiologist's Perspectives on Perioperative Allergies and Penicillin Allergy Evaluations: A National Survey. (external link)
- Glambek, Marte; Kjos, Morten; MÃ¥rli, Marita Torrissen et al. (2025). TrexAB, a novel tetracycline resistance determinant in Streptococcus dysgalactiae. (external link)
- MÃ¥rli, Marita Torrissen; Arntzen, Magnus Øverlie; Allred, Jennie Ann et al. (2025). Self-Immunity Towards a Novel Competence-Induced Streptococcal Peptidoglycan Hydrolase is Mediated by a Fem-Transferase-Like Protein. (external link)
- Mårli, Marita Torrissen; Oppegaard, Oddvar; Porcellato, Davide et al. (2024). Genetic modification of Streptococcus dysgalactiae by natural transformation. (external link)
- Gundersen, Ingunn; Bruun, Trond; Almeland, Stian Kreken et al. (2024). necrotizing soft tissue infections. (external link)
- Alnæs, Marie Bjørbak; Skodvin, Brita; Jahnsen, Jan Anker et al. (2024). “What if the patient has a severe reaction, and it is my fault?” A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling. (external link)
- Tölken, Lea A.; Neufend, Janine V.; Oppegaard, Oddvar et al. (2024). Streptokinase reduces Streptococcus dysgalactiae subsp. equisimilis biofilm formation. (external link)
- Glambek, Marte; Skrede, Steinar; Sivertsen, Audun et al. (2024). Antimicrobial resistance patterns in Streptococcus dysgalactiae in a One Health perspective. (external link)
- Oppegaard, Oddvar; Glambek, Marte; Skutlaberg, Dag Harald et al. (2023). Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999-2021. (external link)
- Alnæs, Marie Bjørbak; Oppegaard, Oddvar; Kittang, Bård Reiakvam et al. (2023). A new pathway for penicillin delabeling in Norway. (external link)
- Kaci, Alba; Jonassen, Christine M; Skrede, Steinar et al. (2023). Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018. (external link)
- Jahagirdar, Sanjeevan; Morris, Lorna; Benis, Nirupama et al. (2022). Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections. (external link)
- Lindemann, Paul Christoffer; Mylvaganam, Haima; Oppegaard, Oddvar et al. (2022). Case Report: Whole-Genome Sequencing of Serially Collected Haemophilus influenzae From a Patient With Common Variable Immunodeficiency Reveals Within-Host Evolution of Resistance to Trimethoprim-Sulfamethoxazole and Azithromycin After Prolonged Treatment With These Antibiotics. (external link)
- Smistad, Marit; Tollersrud, Tore; Austbø, Lars et al. (2021). Molecular detection and genotype characterization of Streptococcus dysgalactiae from sheep flocks with outbreaks of infectious arthritis. (external link)
- Porcellato, Davide; Smistad, Marit; Skeie, Siv Borghild et al. (2021). Whole genome sequencing reveals possible host species adaptation of Streptococcus dysgalactiae. (external link)
- Nybakken, Eirik Jovall; Oppegaard, Oddvar; Gilhuus, Marianne et al. (2020). Identification of Streptococcus dysgalactiae using matrix-assisted laser desorption/ionization-time of flight mass spectrometry; refining the database for improved identification. (external link)
- Bergsten, Helena; Madsen, Martin Bruun; Bergey, Francois et al. (2020). Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. (external link)
- Bruun, Trond; Rath, Eivind; Madsen, Martin Bruun et al. (2020). Risk factors and Predictors of Mortality in Streptococcal Necrotizing Soft-Tissue Infections: A Multicenter Prospective Study. (external link)
- Oppegaard, Oddvar; Skrede, Steinar; Mylvaganam, Haima et al. (2020). Emerging threat of antimicrobial resistance in β-hemolytic streptococci. (external link)
- Rath, Eivind; Skrede, Steinar; Oppegaard, Oddvar et al. (2020). Non-purulent skin and soft tissue infections: predictive power of a severity score and the appropriateness of treatment in a prospective cohort. (external link)
- Oppegaard, Oddvar; Mylvaganam, Haima; Skrede, Steinar et al. (2018). Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis. (external link)
- Kittang, Bård Reiakvam; Pettersen, Veronika Kucharova; Oppegaard, Oddvar et al. (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. (external link)
- Oppegaard, Oddvar; Mylvaganam, Haima; Skrede, Steinar et al. (2017). Clinical and molecular characteristics of infective β-hemolytic streptococcal endocarditis. (external link)
- Oppegaard, Oddvar; Mylvaganam, Haima; Skrede, Steinar et al. (2017). Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations. (external link)
- Bruun, Trond; Oppegaard, Oddvar; Kittang, Bård Reiakvam et al. (2016). Etiology of cellulitis and clinical prediction of streptococcal disease: A prospective study. (external link)
- Oppegaard, Oddvar; Skrede, Steinar; Mylvaganam, Haima et al. (2016). Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway. (external link)
- Bruun, Trond; Oppegaard, Oddvar; Hufthammer, Karl Ove et al. (2016). Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors. (external link)
- Oppegaard, Oddvar; Mylvaganam, Haima; Kittang, Bård Reiakvam (2015). Beta-haemolytic group A, C and G streptococcal infections in Western Norway: a 15-year retrospective survey. (external link)
- Jonsson, Maria Karolina; Hammenfors, Daniel; Oppegaard, Oddvar et al. (2015). A 35-year-old woman with influenza A-associated thrombotic thrombocytopenic purpura. (external link)
- Jordal, Stina; Glambek, Marte; Oppegaard, Oddvar et al. (2015). New tricks from an old cow: infective endocarditis caused by Streptococcus dysgalactiae subsp. dysgalactiae. (external link)
- Siemens, Nikolai; Kittang, Bård Reiakvam; Chakrakodi, Bhavya et al. (2015). Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections. (external link)
- Oppegaard, Oddvar; Mylvaganam, Haima; Skrede, Steinar et al. (2014). Sequence diversity of sicG among group C and G Streptococcus dysgalactiae subspecies equisimilis isolates associated with human infections in western Norway. (external link)
- Oppegaard, Oddvar; Skodvin, Brita; Halse, Anne-Kristine et al. (2013). CD64 as a potential biomarker in septic arthritis. (external link)
Poster
- Mårli, Marita Torrissen; Oppegaard, Oddvar; Porcellato, Davide et al. (2022). An investigation of the competence regulon in Streptococcus dysgalactiae by RNA-seq. (external link)
- Mårli, Marita Torrissen; Oppegaard, Oddvar; Porcellato, Davide et al. (2022). An investigation of the competence regulon of Streptococcus dysgalactiae. (external link)
- Mårli, Marita Torrissen; Porcellato, Davide; Straume, Daniel et al. (2022). A study of competence in Streptococcus dysgalactiae by RNA-seq. (external link)