Vitenskapelig foredrag

• Heggelund, Lars; Rhedin, Samuel; Noucler, Pontus (2025). Can diagnostics be used to streamline the treatment of respiratory infections. (ekstern lenke)
• Stray-Pedersen, Asbjørg; Garred, P; Heggelund, Lars et al. (2003). A boy with severe pulmonal infectious problems due to NKX2.1 haploinsufficiency and mannan-binding lectin deficiency. (ekstern lenke)

Vitenskapelig artikkel

• Granerud, Beathe Kiland; Kaarbø, Mari; Al-Baldawi, Huda et al. (2025). Droplet Digital PCR or Real-Time PCR as a Method for Quantifying SARS-CoV-2 RNA in Plasma-Is There a Difference?. (ekstern lenke)
• Viermyr, Hans-Kittil; Tonby, Kristian; Ponzi, Erica et al. (2024). Safety of baricitinib in vaccinated patients with severe and critical COVID-19 sub study of the randomised Bari-SolidAct trial. (ekstern lenke)
• Markussen, Dagfinn Lunde; Kommedal, Øyvind; Knoop, Siri Tandberg et al. (2024). Microbial aetiology of community-acquired pneumonia in hospitalised adults: A prospective study utilising comprehensive molecular testing. (ekstern lenke)
• Markussen, Dagfinn Lunde; Serigstad, Sondre; Ritz, Christian et al. (2024). Diagnostic Stewardship in Community-Acquired Pneumonia with Syndromic Molecular Testing: A Randomized Clinical Trial. (ekstern lenke)
• Feet, Jon Anders; Müller, Karl Erik; Grewal, Harleen et al. (2024). A retrospective study of non-ventilator hospital-acquired pneumonia in a Norwegian hospital: a serious medical condition in need of better and timelier microbiological diagnostics. (ekstern lenke)
• Barratt-Due, Andreas; Pettersen, Kristin; Dahl, Tuva Børresdatter et al. (2024). Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients. (ekstern lenke)
• Johannessen, Asgeir; Reikvam, Dag Henrik; Aleman, Soo et al. (2024). Clinical trial: An open-label, randomised trial of different re-start strategies after treatment withdrawal in HBeAg negative chronic hepatitis B. (ekstern lenke)
• Murphy, Sarah Louise Mikalsen; Balzer, Nora Reka; Ranheim, Trine et al. (2024). Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study. (ekstern lenke)
• Mesinovic, Munib; Wong, Xin Ci; Rajahram, Giri Shan et al. (2024). At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods. (ekstern lenke)
• Grønseth, Stine; Rogne, Tormod; Heggelund, Lars et al. (2023). Role of fungal burden in risk stratification of HIV-negative patients with Pneumocystis pneumonia: A 12-year, retrospective, observational, multicenter cohort. (ekstern lenke)
• Fløystad, Hans Kristian; Holter, Jan Cato; Husebye, Einar et al. (2023). Nausea Predicts Bacteremia in Immunocompetent Patients with Pneumococcal Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort. (ekstern lenke)
• Trøseid, Marius; Arribas, José R.; Assoumou, Lambert et al. (2023). Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial. (ekstern lenke)
• Trøseid, Marius; Holter, Jan Cato; Holm, Kristian et al. (2023). Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19. (ekstern lenke)
• Abdelhak, Ahmed; Barba, Lorenzo; Romoli, Michele et al. (2023). Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis. (ekstern lenke)
• Murphy, Sarah Louise Mikalsen; Halvorsen, Bente; Holter, Jan Cato et al. (2023). Circulating markers of extracellular matrix remodelling in severe COVID-19 patients. (ekstern lenke)
• Oppen, Kjersti; Brede, Cato; Skadberg, Øyvind et al. (2023). Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS. (ekstern lenke)
• Søvik, Signe; Barratt-Due, Andreas; Kåsine, Trine et al. (2022). Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation. (ekstern lenke)
• Siljan, William Ward; Sivakumaran, Dhanasekaran; Ritz, Christian et al. (2022). Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools. (ekstern lenke)
• Pan, Hongchao; Peto, Richard; Karim, Quarraisha Abdool et al. (2022). Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses. (ekstern lenke)
• Waagsbø, Bjørn; Buset, Eva Margrethe Nor; Longva, Jørn-Åge et al. (2022). Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia. (ekstern lenke)
• Marwali, Eva Miranda; Kekalih, Aria; Yuliarto, Saptadi et al. (2022). Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity. (ekstern lenke)
• Waagsbø, Bjørn; Tranung, Morten; Damås, Jan Kristian et al. (2022). Antimicrobial therapy of community-acquired pneumonia during stewardship efforts and a coronavirus pandemic: an observational study. (ekstern lenke)
• Waagsbø, Bjørn; Stuve, Nora; Afset, Jan Egil et al. (2022). High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting. (ekstern lenke)
• Serigstad, Sondre; Markussen, Dagfinn Lunde; Ritz, Christian et al. (2022). The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemic. (ekstern lenke)
• Garcia-Gallo, Esteban; Merson, Laura; Kennon, Kalynn et al. (2022). ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19. (ekstern lenke)
• Tveita, Anders Aune; Murphy, Sarah Louise Mikalsen; Holter, Jan Cato et al. (2022). High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19. (ekstern lenke)
• Trøseid, Marius; Dahl, Tuva Børresdatter; Holter, Jan Cato et al. (2022). Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies. (ekstern lenke)
• Olsen, Maria Belland; Huse, Camilla; Sousa, Mirta et al. (2022). DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients. (ekstern lenke)
• Oppen, Kjersti; Ueland, Thor; Michelsen, Annika Elisabet et al. (2022). Hepcidin predicts 5-year mortality after community-acquired pneumonia. (ekstern lenke)
• Bouziotis, Jason; Arvanitakis, Marianna; Preiser, Jean-Charles et al. (2022). Association of body mass index with COVID-19 related in-hospital death. (ekstern lenke)
• Degenhardt, Frauke; Ellinghaus, David; Juzenas, Simonas et al. (2022). Detailed stratified GWAS analysis for severe COVID-19 in four European populations. (ekstern lenke)
• Serigstad, Sondre; Ritz, Christian; Faurholt-Jepsen, Daniel et al. (2022). Impact of rapid molecular testing on diagnosis, treatment and management of community-acquired pneumonia in Norway: a pragmatic randomised controlled trial (CAPNOR). (ekstern lenke)
• Serigstad, Sondre; MARKUSSEN, DAGFINN LUNDE; Grewal, Harleen et al. (2022). Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield. (ekstern lenke)
• Cho, Sung-Min; White, Nicole; Premraj, Lavienraj et al. (2022). Neurological manifestations of COVID-19 in adults and children. (ekstern lenke)
• Gonçalves, Bronner P.; Hall, Matthew; Jassat, Waasila et al. (2022). An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients. (ekstern lenke)
• Reyes, Luis Felipe; Murthy, Srinivas; Garcia-Gallo, Esteban et al. (2022). Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study. (ekstern lenke)
• Wainstein, Marina; MacDonald, Samual; Fryer, Daniel et al. (2022). Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC–WHO clinical characterisation protocol. (ekstern lenke)
• Hammer, Quirin; Dunst, Josefine; Christ, Wanda et al. (2022). SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells. (ekstern lenke)
• Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G. et al. (2021). Mapping the human genetic architecture of COVID-19. (ekstern lenke)
• Kåsine, Trine; Riise, Anne Margarita Dyrhol; Barratt-Due, Andreas et al. (2021). Neutrophil count predicts outcome in hospitalized COVID-19 patients. Results from the NOR-Solidarity trial. (ekstern lenke)
• Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent et al. (2021). COVID‐19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study. (ekstern lenke)
• Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent et al. (2021). Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort. (ekstern lenke)
• Reyes, Luis Felipe; Murthy, Srinivas; Garcia-Gallo, Esteban et al. (2021). Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the ISARIC WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study. (ekstern lenke)
• Ueland, Thor; Dyrhol-Riise, Anne Ma; Woll, Bjørn Martin et al. (2021). Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients. (ekstern lenke)
• Aamodt, Anne Hege; Høgestøl, Einar August; Popperud, Trine Haug et al. (2021). Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19. (ekstern lenke)
• Brustugun, Odd; Heggelund, Lars (2021). Koronavaksinering av kreftpasienter. (ekstern lenke)
• Oppen, Kjersti; Ueland, Thor; Siljan, William Ward et al. (2021). Hepcidin and ferritin predict microbial etiology in community-acquired pneumonia. (ekstern lenke)
• Barratt-Due, Andreas; Olsen, Inge Christoffer; Nezvalova-Henriksen, Katerina et al. (2021). Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial. (ekstern lenke)
• Hoel, Hedda Benedicte; Heggelund, Lars; Reikvam, Dag Henrik et al. (2020). Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement. (ekstern lenke)
• Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik et al. (2020). Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19. (ekstern lenke)
• Ueland, Thor; Heggelund, Lars; Lind, Andreas et al. (2020). Elevated plasma sTIM-3 levels in patients with severe COVID-19. (ekstern lenke)
• Holter, Jan Cato; Pischke, Soeren; Boer, Eline de et al. (2020). Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients. (ekstern lenke)
• Siljan, William Ward; Holter, Jan Cato; Michelsen, Annika et al. (2019). Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: Results of a 5-year follow-up cohort study. (ekstern lenke)
• Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset et al. (2018). Low levels of immunoglobulins and mannose-binding lectin are not associated with etiology, severity, or outcome in community-acquired pneumonia. (ekstern lenke)
• Dalgard, Olav; Weiland, Ola; Noraberg, Geir et al. (2017). Sofosbuvir based treatment of chronic hepatitis C genotype 3 infections - A Scandinavian real-life study. (ekstern lenke)
• Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset et al. (2017). Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia. (ekstern lenke)
• Midgard, Håvard; Bjøro, Benedikte; Mæland, Arild et al. (2016). Hepatitis C reinfection after sustained virological response. (ekstern lenke)
• Holter, Jan Cato; Ueland, Thor; Norseth, Jon et al. (2016). Vitamin D Status and Long-Term Mortality in Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort. (ekstern lenke)
• Holter, Jan Cato; Ueland, Thor; Jenum, Pål et al. (2016). Risk factors for long-term mortality after hospitalization for community-acquired pneumonia: a 5-year prospective follow-up study. (ekstern lenke)
• Heggelund, Lars; Gaustad, Peter; Håvelsrud, Othilde Else et al. (2015). Corynebacterium pseudotuberculosis Pneumonia in a veterinary stuent infected during lobaratory work. (ekstern lenke)
• Holter, Jan Cato; Müller, Fredrik; Bjørang, Ola et al. (2015). Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway. (ekstern lenke)
• Pullar, Nadine Durema; Steinum, Harald Otto; Tonby, Kristian et al. (2014). Low prevalence of positive interferon-gamma tests in HIV-positive long-term immigrants in Norway. (ekstern lenke)
• Dale, Einar; Heggelund, Lars; Samdal, Helvi Holm et al. (2010). Dramatisk sykehistorie forårsaket av uvanlig bakterie. (ekstern lenke)
• Damas, JK; Landro, L; Fevang, B et al. (2009). Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication. (ekstern lenke)
• Damås, Jan Kristian; Landrø, Linn Aina Ysland; Fevang, Børre et al. (2009). Enhanced levels of the CCR7 ligands CCL19 and CCL21 in HIV infection: correlation with viral load, disease progression and response to highly active antiretroviral therapy. (ekstern lenke)
• Landrø, Linn Aina Ysland; Damås, Jan Kristian; Halvorsen, Bente et al. (2009). CXCL16 in HIV infection - a link between inflammation and viral replication. (ekstern lenke)
• Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian et al. (2008). Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. (ekstern lenke)
• Heggelund, L; Samdal, H Holm; Eggum, R et al. (2007). Severe case of invasive community-acquired methicillin-resistant Staphylococcus aureus infection in Norway. (ekstern lenke)
• Holven, Kirsten Bjørklund; Damås, Jan Kristian; Yndestad, Arne et al. (2006). Chemokines in children with heterozygous familiar hypercholesterolemia - Selective upregulation of RANTES. (ekstern lenke)
• Fiane, Arnt E; Ueland, Thor; Simonsen, Svein et al. (2005). Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation. (ekstern lenke)
• Fevang, Børre; Mollnes, Tom Eirik; Holm, Are Martin et al. (2005). Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis. (ekstern lenke)
• Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje et al. (2005). Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. (ekstern lenke)
• Heggelund, L; Mollnes, TE; Espevik, Terje et al. (2005). Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. (ekstern lenke)
• Heggelund, L; Mollnes, TE; Espevik, Terje et al. (2005). Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. (ekstern lenke)
• Heggelund, L; Muller, F; Lien, E et al. (2004). Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. (ekstern lenke)
• Heggelund, L; Damås, Jan Kristian; Damas, JK et al. (2004). Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. (ekstern lenke)
• Heggelund, Lars; Flo, T; Berg, K et al. (2004). Soluble toll-like receptor 2 in HIV infection: association with disease progression. (ekstern lenke)
• Heggelund, L; Flo, Trude Helen; Berg, K. et al. (2004). Soluble toll-like receptor 2 in HIV infection: association with disease progression. (ekstern lenke)
• Stylianou, Eva; Bjerkeli, Vigdis; Yndestad, Arne et al. (2003). Raised serum levels of interleukin-18 is associated with disease progression and may contribute to virological treatment failure in HIV-1-infected patients. (ekstern lenke)
• Heggelund, Lars; Mollnes, Tom Eirik; Ueland, Thor et al. (2003). Mannose-Binding Lectin in HIV Infection: Relation to Disease Progression and Highly Active Antiretroviral Therapy. (ekstern lenke)
• Fiane, Arnt E; Videm, Vibeke; Lingaas, PS et al. (2003). Mechanism of complement activation and its role in the inflammatory response following thoraco-abdominal aortic aneurys. (ekstern lenke)
• Fiane, Arnt E.; Videm, Vibeke; Lingaas, Per Snorre et al. (2003). Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair. (ekstern lenke)

Poster

• Kibsgaard, Hanne Loa; Heggelund, Lars; Kofstad, Tone et al. (2024). Diagnostic yield in lower respiratory tract infections; comparing nasopharyngeal swabs with sputum samples. (ekstern lenke)
• Feet, Jon Anders; Müller, Karl Erik; Heggelund, Lars (2024). Ventilator-associated pneumonia in a Norwegian hospital: A retrospective cohort. (ekstern lenke)
• Stray-Pedersen, Asbjørg; Lindman, C.; Stoltenberg, Lauritz et al. (2002). A boy with neurologic abnormalities, subclinical hypothyroidism, respiratory distress and immunodeficiency due to microdelition of chromosome 14q12 and NKX2.1 haploinsufficiency. (ekstern lenke)

Errata

• Markussen, Dagfinn Lunde; Kommedal, Øyvind; Knoop, Siri Tandberg et al. (2024). Corrigendum to “Microbial aetiology of community-acquired pneumonia in hospitalised adults: A prospective study utilising comprehensive molecular testing” [International Journal of Infectious Diseases 143 (2024) 107019]. (ekstern lenke)

Leserinnlegg

• Ueland, Thor; Äikäs, Lauri A.O.; Dahl, Tuva Børresdatter et al. (2023). Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization. (ekstern lenke)
• Gregersen, Ida; Ueland, Thor; Holter, Jan Cato et al. (2022). CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19. (ekstern lenke)
• Ueland, Thor; Holter, Jan Cato; Holten, Aleksander Rygh et al. (2020). Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure: MMP-9 and respiratory failure in COVID-19. (ekstern lenke)
• Siljan, William; Holter, Jan Cato; Nymo, Ståle Haugset et al. (2016). Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome. (ekstern lenke)
• Samuelsen, Ørjan; Thilesen, Carina; Heggelund, Lars et al. (2011). Identification of NDM-1-producing Enterobacteriaceae in Norway. (ekstern lenke)

Doktorgradsavhandling

• Heggelund, Lars (2005). Innate immunity and human immunodeficiency virus infection. Studies on toll-like receptor 2 and manose-binding lectin. (ekstern lenke)

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