Academic article

• Kverneng, Simon Ulvenes; Mostafavi, Sepideh; Mikhaleva, Yana et al. (2025). Platelet mitochondrial complex I and IV activities are not reliable stratification biomarkers in Parkinson's disease. (external link)
• Kverneng, Simon Ulvenes; Stige, Kjersti Eline; Berven, Haakon et al. (2025). Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease. (external link)
• Flønes, Irene; Toker, Lilah; Sandnes, Dagny Ann et al. (2024). Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease. (external link)
• Høyland, Lena Elise; Linden, Magali R Van; Niere, Marc et al. (2024). Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+. (external link)
• Nido, Gonzalo Sanchez; Castelli, Martina Galatea; Mostafavi, Sepideh et al. (2024). Single-nucleus transcriptomics reveals disease- and pathology-specific signatures in α-synucleinopathies. (external link)
• Dick, Fiona; Johanson, Gard Aasmund Skulstad; Tysnes, Ole-Bjørn et al. (2024). Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. (external link)
• Gaare, Johannes Jernqvist; Dölle, Christian; Brakedal, Brage et al. (2023). Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson's disease. (external link)
• Berven, Haakon; Kverneng, Simon Ulvenes; Sheard, Erika et al. (2023). NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease. (external link)
• Brakedal, Brage; Dölle, Christian; Riemer, Frank et al. (2022). The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. (external link)
• Guitton, Romain Guillaume Bernard; Dölle, Christian; Alves, Guido Werner et al. (2022). Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA. (external link)
• Toker, Lilah; Tran, Gia T.; Sundaresan, Janani et al. (2021). Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain. (external link)
• Flønes, Irene Hana; Ricken, Gerda; Klotz, Sigrid et al. (2020). Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease. (external link)
• Dick, Fiona; Nido, Gonzalo Sanchez; Alves, Guido Werner et al. (2020). Differential transcript usage in the Parkinson’s disease brain. (external link)
• Gaare, Johannes Jernqvist; Nido, Gonzalo Sanchez; Dölle, Christian et al. (2020). Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. (external link)
• Osuagwu, Nelson Uchechukwu; Dölle, Christian; Tzoulis, Charalampos (2019). Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or α-synuclein, is localized to the mitochondrial matrix. (external link)
• Dölle, Christian; Bindoff, Laurence; Tzoulis, Charalampos (2018). 3,3'-Diaminobenzidine staining interferes with PCR-based DNA analysis. (external link)
• Buonvicino, Daniela; Mazzola, Francesca; Zamporlini, Federica et al. (2018). Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites. (external link)
• Nido, Gonzalo Sanchez; Dölle, Christian; Flønes, Irene Hana et al. (2018). Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease. (external link)
• Dölle, Christian; Ziegler, Mathias (2017). ADP-ribosylation of DNA moving into focus. (external link)
• Linden, Magali R Van; Niere, Marc; Nikiforov, Andrey et al. (2017). Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools. (external link)
• Brakedal, Brage; Flønes, Irene Hana; Reiter, Simone B. C. Frizell et al. (2017). Glitazone use associated with reduced risk of Parkinson's disease. (external link)
• Flønes, Irene Hana; Fernandez-Vizarra, Erika; Lykouri, Maria et al. (2017). Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage. (external link)
• Flønes, Irene Hana; Sztromwasser, Pawel Szymon; Haugarvoll, Kristoffer et al. (2016). Novel SLC19A3 promoter deletion and allelic silencing in biotin-thiamine-responsive basal ganglia encephalopathy. (external link)
• Dölle, Christian; Flønes, Irene Hana; Nido, Gonzalo Sanchez et al. (2016). Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease. (external link)
• Kulikova, Veronika; Shabalin, Konstantin; Nerinovski, Kirill et al. (2015). Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells. (external link)
• Love, Nick R.; Pollak, Nadine; Dölle, Christian et al. (2015). NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. (external link)
• Linden, Magali R Van; Dölle, Christian; Pettersen, Ina Katrine Nitschke et al. (2015). Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. (external link)
• Skoge, Renate Hvidsten; Dölle, Christian; Ziegler, Mathias (2014). Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels. (external link)
• Niere, Marc; Mashimo, Masato; Agledal, Line et al. (2012). ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose)glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose). (external link)
• Nikiforov, Andrey; Dølle, Christian; Niere, Marc et al. (2011). Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells FROM ENTRY OF EXTRACELLULAR PRECURSORS TO MITOCHONDRIAL NAD GENERATION. (external link)
• Dølle, Christian; Niere, Marc; Lohndal, Emilia et al. (2010). Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. (external link)
• Lau, Corinna; Dølle, Christian; Gossmann, Toni I. et al. (2010). Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. (external link)

Academic literature review

• Dölle, Christian; Tzoulis, Charalampos (2025). NAD augmentation as a disease-modifying strategy for neurodegeneration. (external link)
• Stige, Kjersti Eline; Kverneng, Simon Ulvenes; Sharma, Soumya et al. (2024). The STRAT-PARK cohort: A personalized initiative to stratify Parkinson's disease. (external link)
• Dölle, Christian; Skoge, Renate Hvidsten; Linden, Magali R Van et al. (2013). NAD biosynthesis in humans - enzymes, metabolites and therapeutic aspects. (external link)
• Dölle, Christian; Rack, Johannes Gregor M; Ziegler, Mathias (2013). NAD and ADP-ribose metabolism in mitochondria. (external link)
• Chiarugi, Alberto; Dølle, Christian; Felici, Roberta et al. (2012). The NAD metabolome - a key determinant of cancer cell biology. (external link)
• Pollak, Nadine; Dølle, Christian; Ziegler, Mathias (2007). The power to reduce: pyridine nucleotides - small molecules with a multitude of functions. (external link)

Doctoral dissertation

• Flønes, Irene Hana; Tzoulis, Charalampos; Dölle, Christian et al. (2019). Mitochondrial mechanisms in neurodegeneration. (external link)

Masters thesis

• Osuagwu, Nelson Uchechukwu; Tzoulis, Charalampos; Dölle, Christian (2017). High-resolution subcellular localization of pathogenic proteins in Parkinson's disease. (external link)

Abstract

• Livinskaya, V; Afanasyeva, A; Dölle, Christian et al. (2013). Potential role of cytosolic 5'- nucleotidases in human NAD metabolism. (external link)

Academic lecture

• Dølle, Christian; Agrimi, Gennaro; Palmieri, Ferdinando et al. (2012). Identification of the pathways generating organellar NAD pools using targeted poly-ADP ribose formation. (external link)
• Niere, Marc; Dølle, Christian; Agledal, Line et al. (2010). Dissection of candidate enzymes involved in mitochondrial poly-ADP-ribose degradation. (external link)
• Agledal, Line; Dølle, Christian; Ziegler, Mathias (2009). Alteration of compartment-specific NAD biosynthesis by reduction of individual subcellular NAD pools. (external link)
• Dølle, Christian (2007). Visualization of an enzymatic activity to determine the suborganellar location of mitochondrial proteins. (external link)

Editorial

• Dølle, Christian; Ziegler, Mathias (2009). Application of a coupled enzyme assay to characterize nicotinamide riboside kinases. (external link)

Poster

• Agledal, Line; Dølle, Christian; Ziegler, Mathias (2008). Alteration of isoform-specific NMNAT expression by reduction of subcellular NAD pools. (external link)
• Agledal, Line; Niere, Marc; Dølle, Christian et al. (2007). Expression of NAD biosynthetic enzymes in response to decreased mitochondrial and cytosolic NAD levels. (external link)
• Dølle, Christian (2005). A new potential ADP-ribose acceptor protein in mitochondria. (external link)
• Dølle, Christian (2005). A new potential ADP-ribose acceptor protein in mitochondria. (external link)

See a complete overview of publications in Cristin.