Vitenskapelig artikkel
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Kverneng, Simon Ulvenes; Mostafavi, Sepideh; Mikhaleva, Yana
et al. (2025). Platelet mitochondrial complex I and IV activities are not reliable stratification biomarkers in Parkinson's disease. (ekstern lenke)
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Kverneng, Simon Ulvenes; Stige, Kjersti Eline; Berven, Haakon
et al. (2025). Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease. (ekstern lenke)
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Flønes, Irene; Toker, Lilah; Sandnes, Dagny Ann
et al. (2024). Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease. (ekstern lenke)
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Høyland, Lena Elise; Linden, Magali R Van; Niere, Marc
et al. (2024). Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+. (ekstern lenke)
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Nido, Gonzalo Sanchez; Castelli, Martina Galatea; Mostafavi, Sepideh
et al. (2024). Single-nucleus transcriptomics reveals disease- and
pathology-specific signatures in α-synucleinopathies. (ekstern lenke)
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Dick, Fiona; Johanson, Gard Aasmund Skulstad; Tysnes, Ole-Bjørn
et al. (2024). Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. (ekstern lenke)
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Gaare, Johannes Jernqvist; Dölle, Christian; Brakedal, Brage
et al. (2023). Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson's disease. (ekstern lenke)
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Berven, Haakon; Kverneng, Simon Ulvenes; Sheard, Erika
et al. (2023). NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease. (ekstern lenke)
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Brakedal, Brage; Dölle, Christian; Riemer, Frank
et al. (2022). The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. (ekstern lenke)
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Guitton, Romain Guillaume Bernard; Dölle, Christian; Alves, Guido Werner
et al. (2022). Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA. (ekstern lenke)
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Toker, Lilah; Tran, Gia T.; Sundaresan, Janani
et al. (2021). Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain. (ekstern lenke)
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Flønes, Irene Hana; Ricken, Gerda; Klotz, Sigrid
et al. (2020). Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease. (ekstern lenke)
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Dick, Fiona; Nido, Gonzalo Sanchez; Alves, Guido Werner
et al. (2020). Differential transcript usage in the Parkinson’s disease brain. (ekstern lenke)
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Gaare, Johannes Jernqvist; Nido, Gonzalo Sanchez; Dölle, Christian
et al. (2020). Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. (ekstern lenke)
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Osuagwu, Nelson Uchechukwu; Dölle, Christian; Tzoulis, Charalampos
(2019). Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or α-synuclein, is localized to the mitochondrial matrix. (ekstern lenke)
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Dölle, Christian; Bindoff, Laurence; Tzoulis, Charalampos
(2018). 3,3'-Diaminobenzidine staining interferes with PCR-based DNA analysis. (ekstern lenke)
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Buonvicino, Daniela; Mazzola, Francesca; Zamporlini, Federica
et al. (2018). Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites. (ekstern lenke)
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Nido, Gonzalo Sanchez; Dölle, Christian; Flønes, Irene Hana
et al. (2018). Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease. (ekstern lenke)
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Dölle, Christian; Ziegler, Mathias
(2017). ADP-ribosylation of DNA moving into focus. (ekstern lenke)
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Linden, Magali R Van; Niere, Marc; Nikiforov, Andrey
et al. (2017). Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools. (ekstern lenke)
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Brakedal, Brage; Flønes, Irene Hana; Reiter, Simone B. C. Frizell
et al. (2017). Glitazone use associated with reduced risk of Parkinson's disease. (ekstern lenke)
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Flønes, Irene Hana; Fernandez-Vizarra, Erika; Lykouri, Maria
et al. (2017). Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage. (ekstern lenke)
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Flønes, Irene Hana; Sztromwasser, Pawel Szymon; Haugarvoll, Kristoffer
et al. (2016). Novel SLC19A3 promoter deletion and allelic silencing in biotin-thiamine-responsive basal ganglia encephalopathy. (ekstern lenke)
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Dölle, Christian; Flønes, Irene Hana; Nido, Gonzalo Sanchez
et al. (2016). Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease. (ekstern lenke)
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Kulikova, Veronika; Shabalin, Konstantin; Nerinovski, Kirill
et al. (2015). Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells. (ekstern lenke)
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Love, Nick R.; Pollak, Nadine; Dölle, Christian
et al. (2015). NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. (ekstern lenke)
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Linden, Magali R Van; Dölle, Christian; Pettersen, Ina Katrine Nitschke
et al. (2015). Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. (ekstern lenke)
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Skoge, Renate Hvidsten; Dölle, Christian; Ziegler, Mathias
(2014). Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels. (ekstern lenke)
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Niere, Marc; Mashimo, Masato; Agledal, Line
et al. (2012). ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose)glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose). (ekstern lenke)
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Nikiforov, Andrey; Dølle, Christian; Niere, Marc
et al. (2011). Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells FROM ENTRY OF EXTRACELLULAR PRECURSORS TO MITOCHONDRIAL NAD GENERATION. (ekstern lenke)
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Dølle, Christian; Niere, Marc; Lohndal, Emilia
et al. (2010). Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. (ekstern lenke)
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Lau, Corinna; Dølle, Christian; Gossmann, Toni I.
et al. (2010). Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. (ekstern lenke)
Vitenskapelig oversiktsartikkel/review
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Dölle, Christian; Tzoulis, Charalampos
(2025). NAD augmentation as a disease-modifying strategy for neurodegeneration. (ekstern lenke)
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Stige, Kjersti Eline; Kverneng, Simon Ulvenes; Sharma, Soumya
et al. (2024). The STRAT-PARK cohort: A personalized initiative to stratify Parkinson's disease. (ekstern lenke)
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Dölle, Christian; Skoge, Renate Hvidsten; Linden, Magali R Van
et al. (2013). NAD biosynthesis in humans - enzymes, metabolites and therapeutic aspects. (ekstern lenke)
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Dölle, Christian; Rack, Johannes Gregor M; Ziegler, Mathias
(2013). NAD and ADP-ribose metabolism in mitochondria. (ekstern lenke)
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Chiarugi, Alberto; Dølle, Christian; Felici, Roberta
et al. (2012). The NAD metabolome - a key determinant of cancer cell biology. (ekstern lenke)
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Pollak, Nadine; Dølle, Christian; Ziegler, Mathias
(2007). The power to reduce: pyridine nucleotides - small molecules with a multitude of functions. (ekstern lenke)
Doktorgradsavhandling
Mastergradsoppgave
Sammendrag/Abstract
Vitenskapelig foredrag
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Dølle, Christian; Agrimi, Gennaro; Palmieri, Ferdinando
et al. (2012). Identification of the pathways generating organellar NAD pools using targeted poly-ADP ribose formation. (ekstern lenke)
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Niere, Marc; Dølle, Christian; Agledal, Line
et al. (2010). Dissection of candidate enzymes involved in mitochondrial poly-ADP-ribose degradation. (ekstern lenke)
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Agledal, Line; Dølle, Christian; Ziegler, Mathias
(2009). Alteration of compartment-specific NAD biosynthesis by reduction of individual subcellular NAD pools. (ekstern lenke)
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Dølle, Christian
(2007). Visualization of an enzymatic activity to determine the suborganellar location of mitochondrial proteins. (ekstern lenke)
Leder
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