Research groups
Research
Molecular mechanisms of cell adehsion
The Gullberg laboratory has characterized the integrin α11β1, which is expressed on subsets of normal fibroblasts and on carcinoma-associated fibroblasts. Cells lacking α11β1 display disturbed cell-collagen interactions, altered metalloproteinase synthesis and reduced cell proliferation. Major projects within the group aim to further understand the role of this collagen receptor and other fibroblast integrins during health and in disease.
Teaching
MEDOD1
MEDOD2
BMED320
BMED325
BMED330
FARM260
Publications
2024
- Stewart, Daniel C.; Brisson, Becky K.; Yen, William K. et al. (2024). Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing. (external link)
- Musiime, Moses; Murugan Erusappan, Pugazendhi; Cukierman, Edna et al. (2024). Fibroblast integrin α11β1 is a collagen assembly receptor in mechanoregulated fibrillar adhesions. (external link)
2023
- Zeltz, Cedric; Gullberg, Marion Kusche; Heljasvaara, Ritva Leena et al. (2023). Novel roles for cooperating collagen receptor families in fibrotic niches. (external link)
- Sawant, Mugdha; Wang, Fang; Koester, Janis et al. (2023). Ablation of integrin-mediated cell-collagen communication alleviates fibrosis. (external link)
- Grigorian, Andre; Gullberg, Elon Donald; Musiime, Moses (2023). Matrix Stiffness-dependent Regulation of Integrin α11β1 Expression. (external link)
- Bieber, Katja; Bezdek, Siegfried; Gupta, Yask et al. (2023). Forward genetics and functional analysis highlight Itga11 as a modulator of murine psoriasiform dermatitis. (external link)
2022
- Farndale, Richard W; Sonnenberg, Arnoud; DiPersio, C. Michael et al. (2022). What does it take to be a collagen receptor?. (external link)
- Zeltz, Cedric; Navab, Roya; Heljasvaara, Ritva Leena et al. (2022). Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker?. (external link)