Academic article

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• Gitte Dam; Henning Grønbæk; Halfdan Sorbye et al. (2020). Prospective Study of Chromogranin A as a Predictor of Progression in Patients with Pancreatic, Small-Intestinal, and Unknown Primary Neuroendocrine Tumors. (external link)
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• Andreas Venizelos; Hege Elvebakken; Aurel Perren et al. (2021). The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
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• Dimitrios Papantoniou; Malin Grönberg; Espen Thiis-Evensen et al. (2023). Treatment efficacy in a metastatic small intestinal neuroendocrine tumour grade 2 cohort. (external link)
• Halfdan Sørbye; P Pfeiffer; N Cavalli-Bjorkman et al. (2009). Clinical Trial Enrollment, Patient Characteristics, and Survival Differences in Prospectively Registered Metastatic Colorectal Cancer Patients. (external link)
• Halfdan Sorbye; Anca Dragomir; Magnus Sundström et al. (2015). High BRAF mutation frequency and marked survival differences in subgroups according to KRAS/BRAF mutation status and tumor tissue availability in a prospective population-based metastatic colorectal cancer cohort. (external link)
• Julian Hamfjord; Tormod Kyrre Guren; Olav Dajani et al. (2019). Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy. (external link)
• Staffan Welin; Halfdan Sørbye; Sigrunn Sebjørnsen et al. (2011). Clinical effect of Temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy. (external link)
• Maria Thomsen; Marianne Guren; Eva Skovlund et al. (2017). Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status. (external link)
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• Halfdan Sorbye; Murielle Mauer; Thomas Gruenberger et al. (2012). Predictive Factors for the Benefit of Perioperative FOLFOX for Resectable Liver Metastasis in Colorectal Cancer Patients (EORTC Intergroup Trial 40983). (external link)
• Line Schmidt Tarpgaard; Maj Sofie Ørum-Madsen; Ib Jarle Christensen et al. (2016). TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: A potential novel approach to the treatment of metastatic colorectal cancer. (external link)
• Arvind Dasari; Kathan Mehta; Lauren Averett Byers et al. (2018). Comparative study of lung and extrapulmonary poorly differentiated neuroendocrine carcinomas: A SEER database analysis of 162,983 cases. (external link)
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• Abir Salwa Ali; Malin Grönberg; Birgitte Federspiel et al. (2017). Expression of p53 protein in high-grade gastroenteropancreatic neuroendocrine carcinoma. (external link)
• Abir Salwa Ali; Aurel Perren; Cecilia Lindskog et al. (2020). Candidate protein biomarkers in pancreatic neuroendocrine neoplasms grade 3. (external link)
• Halfdan Sørbye; Bengt Glimelius; Å Berglund et al. (2004). Multicentre phase II study of Nordic 5-fluorouracil and folinic acid bolus schedule combined with oxaliplatin as first-line treatment of metastatic colorectal cancer. (external link)
• Arvind Dasari; Chan Shen; Anjali Devabhaktuni et al. (2022). Survival According to Primary Tumor Location, Stage, and Treatment Patterns in Locoregional Gastroenteropancreatic High-grade Neuroendocrine Carcinomas. (external link)
• Nils Hovdenak; Halfdan Sørbye; Olav Dahl (2005). SSucralfate does not ameliorate acute radiation proctitis: Randomised study and meta-analysis. (external link)
• Martin Fassnacht; Massimo Terzolo; Bruno Allolio et al. (2012). Combination Chemotherapy in Advanced Adrenocortical Carcinoma. (external link)
• Janne Beathe Kjersem; Tone Ikdahl Andersen; Tormod Kyrre Guren et al. (2012). Let-7 miRNA-binding site polymorphism in the KRAS 3 ' UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab. (external link)
• Emerik Osterlund; Ari Ristimäki; Markus J. Mäkinen et al. (2023). Atypical (non-V600E) BRAF mutations in metastatic colorectal cancer in population and real-world cohorts. (external link)
• Halfdan Sorbye; Eric Baudin; Ivan Borbath et al. (2019). Unmet needs in high-grade gastroenteropancreatic neuroendocrine neoplasms (WHO G3). (external link)
• Line Schmidt Tarpgaard; Ib J. Christensen; Gunilla Høyer-Hansen et al. (2015). Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab. (external link)
• Per Pfeiffer; Halfdan Sorbye; Camilla Qvortrup et al. (2015). Maintenance therapy with cetuximab every second week in the first-line treatment of metastatic colorectal cancer: the NORDIC-7.5 Study by the Nordic Colorectal Cancer Biomodulation Group. (external link)
• Erik Tanis; Bernard Nordlinger; Murielle Mauer et al. (2014). Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983. (external link)
• Halfdan Sørbye; Øystein Bruserud; Olav Dahl (2001). Oxaliplatin-induced haematological emergency with an immediate severe thrombocytopenia and hemolysis. Case report. (external link)
• Bengt Glimelius; Halfdan Sørbye; L Balteskard et al. (2008). A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer. (external link)
• Halfdan Sørbye; Dag Jensen; Olav Dahl (1998). Lymphocele after retroperitoneal surgery for testicular or extragonadal germ cell tumors may mimic recurrence. (external link)
• Halfdan Sorbye; Geir Olav Hjortland; L.W. Vestermark et al. (2024). NETest in advanced high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Synne Wollen Steen; Halfdan Sorbye; Mehran Jazbani et al. (2023). Takotsubosyndrom under behandling med fluorouracil. (external link)
• Håvard Trønnes; Hans Kristian Haugland; Albert N. Bekassy et al. (2012). Small Cell Lung Cancer in a 14-Year-Old Girl. (external link)
• Stine Brændegaard Winther; Pia Österlund; Åke Berglund et al. (2017). Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9. (external link)
• Stein Gunnar Larsen; Mariusz Adam Goscinski; Svein Dueland et al. (2021). Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients. (external link)
• Laurids Ø. Poulsen; Camilla Qvortrup; Per Pfeiffer et al. (2015). Review on adjuvant chemotherapy for rectal cancer-why do treatment guidelines differ so much?. (external link)
• Julian Hamfjord; Tormod Kyrre Guren; Bengt Glimelius et al. (2021). Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer. (external link)
• Kjell Kåre Øvrebø; Asbjørn Svardal; Stener Kvinnsland et al. (1999). Glutathione modulation changes the penetration of N-3H-methyl-N-nitro-N-nitrosoguanidine into the gastric mucosa of rats. (external link)
• Kjell Kåre Øvrebø; Halfdan Sørbye; Asbjørn Svardal et al. (1997). Glutathione and N-acetylcysteine reduce gastric mucosal blood flow in rats. (external link)
• Kristine Øverås Aasebø; Jarle Bruun; Christian Holst Bergsland et al. (2022). Prognostic role of tumour infiltrating lymphocytes and macrophages in relation to tumour MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients. (external link)
• Halfdan Sørbye; Olav Dahl (2004). Transient CEA increase at start of oxaliplatin combination therapy for metastatic colorectal cancer. (external link)
• Artur Mezheyeuski; Fredrik Pontén; Per-Henrik Edqvist et al. (2019). Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study. (external link)
• Ulrich Peter Knigge; Magnus Kjellman; Henning Grønbæk et al. (2025). Association rule mining of clinical and biomarker data in neuroendocrine tumors: A prospective study on disease progression. (external link)
• Mairéad G. McNamara; Halfdan Sørbye; Nehara Begum et al. (2025). Controversies in NEN: An ENETS position statement on the treatment of patients with Grade 3 well-differentiated neuroendocrine tumours of the gastro-enteropancreatic tract. (external link)
• Sebastian Meltzer; Anne Negård; Kine Mari Bakke et al. (2022). Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer. (external link)
• Halfdan Sørbye; Dag Jensen; Olav Dahl (1998). Lymphocele after retroperitoneal surgery for testicular or extragonadal germ cell tumors may mimic recurrence. (external link)
• Artur Mezheyeuski; Maja Bradic Lindh; Tormod Kyrre Guren et al. (2016). Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer. (external link)
• B Nordlinger; T Gruenberger; Halfdan Sørbye et al. (2008). Surgery vs surgery and chemotherapy for colorectal liver metastases. (external link)
• Julian Hamfjord; Tormod Kyrre Guren; Bengt Glimerius et al. (2024). Exploring Early Kinetic Profiles of CEA, ctDNA and cfDNA in Patients With RAS-/BRAF-Mutated Metastatic Colorectal Cancer. (external link)
• Maria Thomsen; Christian Kersten; Halfdan Sorbye et al. (2016). Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer. (external link)
• Jon-Helge Angelsen; Asgaut Viste; Inger Marie Løes et al. (2015). Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases. (external link)
• Kristine Aasebø; Anca Dragomir; Magnus Sundström et al. (2019). Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients. (external link)
• Anja Rinke; Christoph J. Auernhammer; Lisa Bodei et al. (2021). Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine?. (external link)
• Rodney J. Hicks; Clarisse Dromain; Wouter De Herder et al. (2021). ENETS standardized (synoptic) reporting for molecular imaging studies in neuroendocrine tumours. (external link)
• Inger Marie Løes; Heike Immervoll; Halfdan Sorbye et al. (2016). Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases. (external link)
• Halfdan Sorbye; Liv Sylvi Meyer; Kjerstin Elisabeth Skrede Mordal et al. (2020). Patient reported symptoms, coping and quality of life during somatostatin analogue treatment for metastatic small- intestinal neuroendocrine tumours. (external link)
• Gabor Isivan Liposits; Jesper Ryg; Halla Skuladottir et al. (2022). Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study. (external link)
• Espen Thiis-Evensen; Magnus Kjellman; Ulrich Knigge et al. (2022). Plasma protein biomarkers for the detection of pancreatic neuroendocrine tumors and differentiation from small intestinal neuroendocrine tumors. (external link)
• Kaitlyn K.H. Goey; Halfdan Sorbye; Bengt Glimelius et al. (2018). Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group. (external link)
• Henning Langen Stokmo; Mahmoud Aly; Inger Marie Bowitz Lothe et al. (2022). Volumetric parameters from [18F]FDG PET/CT predicts survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Maria Thomsen; Eva Skovlund; Halfdan Sorbye et al. (2018). Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome. (external link)
• Eva Tiensuu Janson; Ulrich Knigge; Gitte Dam et al. (2021). Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Halfdan Sorbye; Staffan Welin; Seppo W. Langer et al. (2013). Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): The NORDIC NEC study. (external link)
• Halfdan Sørbye; Olav Dahl (2003). Carcinoembryonic antigen surge in metastatic colorectal cancer patients responding to Oxaliplatin combination chemotherapy: Implications for tumor marker monitoring and guidelines. (external link)
• Kjell Kåre Øvrebø; Knut Svanes; Steinar Aase et al. (2002). Gastric mucosa lesions induced by duodenogastric reflux increase the penetration of N-[3H]-methyl-N-nitro-N-nitrosoguanidine into the corpus mucosa of rats. (external link)
• Halfdan Sorbye; Eric Baudin; Aurel Perren (2018). The problem of high-grade gastroenteropancreatic neuroendocrine neoplasms: Well-differentiated neuroendocrine tumors, neuroendocrine carcinomas, and beyond. (external link)
• Andreas Venizelos; Halfdan Sorbye; Hege Elvebakken et al. (2023). Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Gudrun Maria Waaler Bjørnelv; Svein Dueland; Pål Dag Line et al. (2018). Cost-effectiveness of liver transplantation in patients with colorectal metastases confined to the liver.. (external link)
• Stian Knappskog; Tobias Grob; Andreas Venizelos et al. (2023). Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced Gastroenteropancreatic Neuroendocrine Carcinoma. (external link)
• Bernard Nordlinger; Halfdan Sorbye; Bengt Glimelius et al. (2013). Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. (external link)
• Halfdan Sørbye (2008). Prognostic clinical factors in metastatic colorectal cancer. (external link)
• Tormod Kyrre Guren; Maria Thomsen; Elin H. Kure et al. (2017). Cetuximab in treatment of metastatic colorectal cancer: Final survival analyses and extended RAS data from the NORDIC-VII study. (external link)
• Hege Elvebakken; Geir Olav Hjortland; Herish Garresori et al. (2023). Impact of KRAS and BRAF mutations on treatment efficacy and survival in high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Pål Joranger; Arild Nesbakken; Geir Hoff et al. (2015). Modeling and Validating the Cost and Clinical Pathway of Colorectal Cancer. (external link)
• Jon-Helge Angelsen; Arild Horn; Halfdan Sorbye et al. (2017). Population-based study on resection rates and survival in patients with colorectal liver metastasis in Norway. (external link)
• Pål Joranger; Arild Nesbakken; Halfdan Sorbye et al. (2019). Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach. (external link)
• Siren Morken; Seppo W. Langer; Anna Sundlöv et al. (2023). Phase II study of everolimus and temozolomide as first-line treatment in metastatic high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Nina Cavalli-Björkman; Camilla Qvortrup; Sigrunn Sebjørnsen et al. (2012). Lower treatment intensity and poorer survival in metastatic colorectal cancer patients who live alone. (external link)
• Sampsa Kinos; Helga Hagman; Päivi Halonen et al. (2024). Detailed analysis of metastatic colorectal cancer patients who developed cardiotoxicity on another fluoropyrimidine and switched to S-1 treatment (subgroup analysis of the CardioSwitch-study). (external link)
• Magne Kjell Tveit; Tormod Kyrre Guren; Bengt Glimelius et al. (2012). Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDIC-VII Study. (external link)
• Halfdan Sorbye; Milada Cvancarova Småstuen; Camilla Qvortrup et al. (2013). Age-dependent improvement in median and long-term survival in unselected population-based Nordic registries of patients with synchronous metastatic colorectal cancer. (external link)
• Hege Elvebakken; Aurel Perren; Jean-Yves Scoazec et al. (2020). A Consensus-Developed Morphological Re-Evaluation of 196 High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms and Its Clinical Correlations. (external link)
• Luís Nunes; Kristine Aasebø; Lucy Mathot et al. (2020). Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis. (external link)
• Kristine Aasebø; Anca Dragomir; Magnus Sundström et al. (2020). CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup. (external link)
• Anita Sveen; Inger Marie Løes; Sharmini Alagaratnam et al. (2016). Intra-patient inter-metastatic genetic heterogeneity in colorectal cancer as a key determinant of survival after curative liver resection. (external link)
• Kjell Kåre Øvrebø; Halfdan Sørbye; Stener Kvinnsland et al. (1998). Effect of gastric secretion on the penetration of N-3H-methyl-N-nitro-N-nitrosoguanidine into the gastric mucosa of rats. (external link)
• Nils Hovdenak; Åsa Karlsdottir; Halfdan Sørbye et al. (2003). Profiles and time course of acute radiation toxicity symptoms during conformal radiotherapy for cancer of the prostate. (external link)
• Kjell Kåre Øvrebø; Knut Svanes; Steinar Torbjørn Aase et al. (2002). Duodenogastric reflux increases the penetration of N-3H-methyl-N-nitro-N-nitrosoguanidine into the antral mucosa of rats. A possible role for mucosal erosions and increased cell proliferation in gastric carsinogenesis. (external link)
• Elinor Margrethe Chelsom Vogt; Katrin Hammerling; Halfdan Sorbye et al. (2021). Feminizing adrenal tumor identified by plasma steroid profiling. (external link)
• Pia Österlund; Halfdan Sorbye; Per Pfeiffer et al. (2016). Drug costs and benefits of medical treatments in high-unmet need solid tumours in the Nordic countries. (external link)
• Aurel A. Perren; Anne Couvelard; Jean-Yves Scoazec et al. (2017). ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Pathology-Diagnosis and Prognostic Stratification. (external link)
• Artur Mezheyeuski; Carina Strell; Ina Hrynchyk et al. (2017). Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer. (external link)
• Stein Gunnar Larsen; Mariusz Adam Goscinski; Svein Dueland et al. (2022). Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients. (external link)
• Anne Hansen Ree; Jurate Saltyte Benth; Hanne Mari Hamre et al. (2024). First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial. (external link)
• Hans-Christian Pommergaard; Kirstine Nielsen; Halfdan Sorbye et al. (2021). Surgery of the primary tumour in 201 patients with high-grade gastroenteropancreatic neuroendocrine and mixed neuroendocrine-non-neuroendocrine neoplasms. (external link)
• C Qvortrup; M Yilmaz; Dagfinn Øgreid et al. (2008). Chronomodulated capecitabine in combination with short-time oxaliplatin: a Nordic phase II study of second-line therapy in patients with metastatic colorectal cancer after failure to irinotecan and 5-flourouracil. (external link)
• Gabor Liposits; Halla Skuladottir; Jesper Ryg et al. (2022). The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—The Randomized NORDIC9-Study. (external link)
• Halfdan Sorbye; Enrique Grande; Marianne Pavel et al. (2023). European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma. (external link)
• Halfdan Sorbye; Geir Olav Hjortland; Lene Weber Vestermark et al. (2025). Characteristics and treatment outcome in a prospective cohort of 639 advanced high-grade digestive neuroendocrine neoplasms (NET G3 and NEC). The NORDIC NEC 2 study. (external link)
• Gabor Liposits; Stine B. Winther; Jesper Ryg et al. (2023). The effect of BRAF^V600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study. (external link)
• Eva Tiensuu Janson; Halfdan Sorbye; Staffan Welin et al. (2014). Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. (external link)
• Bernard Nordlinger; Halfdan Sørbye; Bengt Glimelius et al. (2008). Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. (external link)
• Renate Berget Galleberg; Ulrich Peter Knigge; Eva M. Tiensuu Janson et al. (2017). Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas. (external link)
• Jan P. Dumanski; Chiara Rasi; Peyman Björklund et al. (2017). A MUTYH germline mutation is associated with small intestinal neuroendocrine tumors. (external link)
• ET Janson; Halfdan Sørbye; S Welin et al. (2010). Nordic Guidelines 2010 for diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours. (external link)
• Gabor Liposits; Henrik Eshoj; Sören Möller et al. (2021). Quality of life in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—the randomized NORDIC9-study. (external link)
• Marianne Pavel; Juan W Valle; Barbro Eriksson et al. (2017). ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Systemic Therapy-Biotherapy and Novel Targeted Agents. (external link)
• Magnus Kjellman; Ulrich Knigge; Staffan Welin et al. (2020). A plasma protein biomarker strategy for detection of small intestinal neuroendocrine tumors. (external link)
• Anne Hansen Ree; Eirik Høye; Qin Ying Esbensen et al. (2024). Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade. (external link)
• Arunabha Roy; David Cunningham; Robert Hawkins et al. (2012). Docetaxel combined with irinotecan or 5-fluorouracil in patients with advanced oesophago-gastric cancer: a randomised phase II study. (external link)
• Bengt Glimelius; Hans Garmo; Åke Berglund et al. (2011). Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer. (external link)
• Halfdan Sørbye; Kristian Guttu; Hjørtur Gislason et al. (1993). Gastric mucosal injury and associated changes in mucosal blood flow and gastric fluid secretion caused by dimethyl sulphoxide (DMSO) in rats. (external link)
• Knut Jørgen Labori; Kristoffer Lassen; Dag Hoem et al. (2017). Neoadjuvant chemotherapy versus surgery first for resectable pancreatic cancer (Norwegian Pancreatic Cancer Trial - 1 (NorPACT-1)) – study protocol for a national multicentre randomized controlled trial. (external link)
• Abir Salwa Ali; Seppo W. Langer; Birgitte Federspiel et al. (2020). PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3. (external link)
• Christina Siesing; Halfdan Sorbye; Anca Dragomir et al. (2017). High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer. (external link)
• Esben Andreas Carlsen; Nicola Fazio; Dan Granberg et al. (2019). Peptide receptor radionuclide therapy in gastroenteropancreatic NEN G3: A multicenter cohort study. (external link)
• S.B. Winther; P. Østerlund; Å Berglund et al. (2016). NORDIC9: A randomized phase II trial exploring treatment of older patients with metastatic colorectal cancer (mCRC) by comparing full dose monotherapy (S-1 followed by irinotecan) with reduced combination regimen (S-1/oxaliplatin followed by S-1/irinotecan). (external link)
• Rocio Garcia-Carbonero; Halfdan Sorbye; Eric Baudin et al. (2016). ENETS consensus guidelines for high-grade gastroenteropancreatic neuroendocrine tumors and neuroendocrine carcinomas. (external link)
• Stine Brændegaard Winther; Kanita Zubcevic; Camilla Qvortrup et al. (2016). Experience with S-1 in older Caucasian patients with metastatic colorectal cancer (mCRC): Findings from an observational chart review. (external link)
• Halfdan Sørbye; Olav Dahl (2003). Nordic 5-Fluorouracil/Leucovorin bolus schedule combined with Oxaliplatin (Nordic FLOX)as first-line treatment of metastatic colorectal cancer. (external link)
• Abir Salwa Ali; Malin Grönberg; Seppo Wang Langer et al. (2018). Intravenous versus oral etoposide: efficacy and correlation to clinical outcome in patients with high-grade metastatic gastroenteropancreatic neuroendocrine neoplasms (WHO G3). (external link)
• Kjell Kåre Øvrebø; Steinar Aase; Ketil Grong et al. (2002). Ulceration as a possible link between duodenogastric reflux and neoplasms in the stomach of rats. (external link)
• P. Osterlund; S. Kinos; P. Pfeiffer et al. (2022). Continuation of fluoropyrimidine treatment with S-1 after cardiotoxicity on capecitabine- or 5-fluorouracil-based therapy in patients with solid tumours: a multicentre retrospective observational cohort study. (external link)
• Sven-Petter Haugvik; Eva Tiensuu Janson; Pia Osterlund et al. (2016). Surgical Treatment as a Principle for Patients with High-Grade Pancreatic Neuroendocrine Carcinoma: A Nordic Multicenter Comparative Study. (external link)
• Hege Elvebakken; Andreas Venizelos; Aurel Perren et al. (2024). Treatment outcome according to genetic tumour alterations and clinical characteristics in digestive high-grade neuroendocrine neoplasms. (external link)

Conference abstract

• Bernard Nordlinger; Halfdan Sorbye; Bengt Glimelius et al. (2012). Long term survival data from EORTC Study 40983:perioperative chemotherapy for resectable liver metastasesfrom colorectal cancer. (external link)
• Halfdan Sorbye; Andreas Venizelos; Hege Elvebakken et al. (2021). Molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms. (external link)
• B Nordlinger; Halfdan Sørbye; M Debois et al. (2005). Feasibility and risks of pre-operative chemotherapy (CT) with Folfox 4 and surgery for resectable colorectal cancer liver metastases (LM). Interim results of the EORTC Intergroup randomized phase III study 40983. (external link)
• C Qvortrup; M Cvancarova; B. Glimelius et al. (2012). AGE DEPENDENT INCREASE IN MEDIAN AND LONG-TERM SURVIVAL IN 29 628 METASTATIC COLORECTAL CANCER (MCRC) SCANDINAVIAN PATIENTS DURING THE PAST TWO DECADES. (external link)
• Halfdan Sorbye; Staffan Welin; Seppo W. Langer et al. (2012). Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal poorly differentiated neuroendocrine carcinoma: The NORDIC NEC study. (external link)
• Per Pfeiffer; Bengt Glimelius; Stine Brændegaard Winther et al. (2019). Randomised trial of cetuximab every 2 weeks with FOLFIRI or cetuximab with alternating FOLFIRI/FOLFOX in patients with RAS and BRAF wild type metastatic colorectal cancer: Nordic 8 results. (external link)
• Georg Gjorgji Dimcevski; Spiros Kotopoulis; Tormod Karlsen Bjånes et al. (2016). Ultrasound and microbubble enhanced treatment of inoperable pancreatic adeonocarcinoma. (external link)
• Stian Knappskog; Halfdan Sorbye; Tim Grob et al. (2022). Mutation spectrum in liquid versus solid biopsies from advanced digestive neuroendocrine carcinoma patients. (external link)
• Julian Hamfjord; Tormod Kyrre Guren; Olav Dajani et al. (2018). Total circulating cell-free DNA (cfDNA) as a prognostic biomarker in metastatic colorectal cancer prior to first-line oxaliplatin-based chemotherapy. (external link)
• K Svanes; Hjørtur Gislason; Jon Erik Grønbech et al. (1993). Role of blood flow in the healing of gastric mucosal lesions.. (external link)
• Baddar Pervaiz Butt; Henning Langen Stokmo; Mona Elisabeth Rootwelt-Revheim et al. (2021). Folfirinox in the treatment of advanced gastroenteropancreatic neuroendocrine carcinomas. (external link)
• Magne Kjell Tveit; Tormod Kyrre Guren; Bengt Glimelius et al. (2010). Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: the Nordic VII study (NCT00145314), by the Nordic colorectal cancer biomodulation group. (external link)
• Halfdan Sorbye; Staffan Welin; Seppo Langer et al. (2013). Ki-67 Proliferative Index Predicts Response to Chemotherapy and Survival in 252 Patients with High-Grade Gastrointestinal Neuroendocrine Carcinoma (WHO G3). (external link)
• Per Pfeiffer; Halfdan Sorbye; Camilla Qvortrup et al. (2012). Maintenance therapy with biweekly cetuximab (C) in the first-line treatment of metastatic colorectal cancer (mCRC): The NORDIC 7.5 study (NCT00660582), by the Nordic Colorectal Cancer Biomodulation Group. (external link)
• T Gruenberger; Halfdan Sørbye; M Debois et al. (2006). Tumor response to pre-operative chemotherapy (CT) with FOLFOX-4 for resectable colorectal cancer liver metastases (LM). Interim results of EORTC Intergroup randomized phase III study 40983. (external link)
• Bernard Nordlinger; Halfdan Sorbye; Bengt Glimelius et al. (2012). EORTC liver metastases intergroup randomized phase III study 40983: Long-term survival results. (external link)
• Line Schmidt Tarpgaard; Tormod Kyrre Guren; Bengt Glimelius et al. (2012). Plasma concentrations of YKL-40 in chemo-naive patients with metastatic colorectal cancer treated with FLOX with or without cetuximab: Results from the NORDIC VII study. (external link)

Academic literature review

• Halfdan Sorbye; Grace Kong; Simona Grozinsky-Glasberg (2020). PRRT in high-grade gastroenteropancreatic neuroendocrine neoplasms (WHO G3). (external link)
• Manfred P. Lutz; John R. Zalcberg; Rob Glynne-Jones et al. (2016). Second St. Gallen European Organisation for Research and Treatment of Cancer Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer. (external link)
• Halfdan Sorbye; Grace Kong; Simona Grozinsky-Glasberg et al. (2024). PRRT in high-grade digestive neuroendocrine neoplasms (NET G3 and NEC). (external link)
• Halfdan Sorbye; Jonathan Strosberg; Eric Baudin et al. (2014). Gastroenteropancreatic high-grade neuroendocrine carcinoma. (external link)
• Martin Biermann; Boel Johnsen; Halfdan Sørbye et al. (2009). Positronemisjonstomografi ved nevroendokrine svulster. (external link)
• Nikolaos Andreatos; Patrick W. McGarrah; Mohamad Bassam Sonbol et al. (2023). Managing Metastatic Extrapulmonary Neuroendocrine Carcinoma After First-Line Treatment. (external link)
• Halfdan Sørbye; M Brændengen; L Balteskard (2008). Palliativ kjemoterapi og strålebehandling ved metastatisk kolorectalkreft. (external link)
• Gitte Dam; Henning Grønbæk; Anna Sundlöv et al. (2023). Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms. (external link)
• Kaitlyn K.H. Goey; Remi Mahmoud; Halfdan Sorbye et al. (2018). Reporting of patient characteristics and stratification factors in phase 3 trials investigating first-line systemic treatment of metastatic colorectal cancer: A systematic review. (external link)

Academic book chapter

• Ragnar Telhaug; Jan Erik Varhaug; Halfdan Sørbye et al. (2009). Endokrine svulster. (external link)
• RM Bremnes; P Endresen; Halfdan Sørbye (1999). Antimetabolitter. (external link)
• Halfdan Sørbye (2008). The use of Chemotherapy for Neuroendocrine Tumors. (external link)
• Georg Gjorgji Dimcevski; Spiros Kotopoulis; Dag Hoem et al. (2013). Ultrasound-assisted treatment of an inoperable pancreatic cancer. (external link)
• Halfdan Sorbye (2014). Recurrence Patterns After Resection of Liver Metastases from Colorectal Cancer. (external link)

Letter to the editor

• Halfdan Sorbye (2019). Ekspertpanel for ny vurdering ved alvorlig sykdom. (external link)
• Halfdan Sorbye; Murielle Mauer; Bernard Nordlinger (2015). Reply to letter: "Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup Trial 40983)". (external link)

Journal corrigendum

• Manfred P. Lutz; John R. Zalcberg; Rob Glynne-Jones et al. (2016). Erratum: Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" (European Journal of Cancer (2016) 68 (208?209) (S0959804916320780) (10.1016/j.ejca.2016.04.010)). (external link)
• Halfdan Sorbye; Geir Olav Hjortland; Lene Weber Vestermark et al. (2025). Correction: Characteristics and treatment outcome in a prospective cohort of 639 advanced high-grade digestive neuroendocrine neoplasms (NET G3 and NEC). The NORDIC NEC 2 study. (external link)

Conference poster

• Anne Hansen Ree; Hanne Mari Hamre; Christian Kersten et al. (2021). Repeat sequential oxaliplatin-based chemotherapy (FLOX) and nivolumab versus FLOX alone as first-line treatment of microsatellite-stable (MSS) metastatic colorectal cancer (mCRC): Initial results from the randomized METIMMOX study. (external link)
• Halfdan Sørbye; Bengt Glimelius; Åke Berglund et al. (2003). Nordic 5-fluorouracil/folinic acid bolus schedule combined with oxaliplatin (FLOX) as first-line treatment to metastatic colorectal cancer. (external link)
• Pål Joranger; Arild Nesbakken; Geir Hoff et al. (2014). Development and validation of a Norwegian model for colorectal cancer. (external link)
• Sebastian Meltzer; Anne Negård; Hanne Mari Hamre et al. (2022). Early radiologic signal of nivolumab responsiveness after short-course oxaliplatin-based chemotherapy in microsatellite-stable (MSS) metastatic colorectal cancer (mCRC).. (external link)
• K Guttu; Halfdan Sorbye; K. Svanes et al. (1993). Effect of restricted hyperaemic response and systemic alkalinization on gastric luminal bicarbonate release and mucosal restitution after hyperomolar damage in the cat.. (external link)

Editorial/Leader article

• Halfdan Sorbye (2012). Palliative chemotherapy in elderly patients with metastatic colorectal cancer: Do we know how it should be used?. (external link)

Conference lecture

• Bengt Glimelius; Halfdan Sørbye; L Balteskard et al. (2005). A randomised phase III multicenter trial comparing irinotecan in combination with 5FU and folinic acid (FU/FA) given according to the Nordic bolus schedule to irinotecan in combination with 5FU/FA given according to the bolus/infused de Gramont schedule, in patients with metastatic colorectal cancer. (external link)
• Pål Joranger; Arild Nesbakken; Geir Hoff et al. (2015). Modell for å beregne overlevelse og kostnader av behandling for kolorektal cancer. (external link)

Doctoral thesis (PhD)

• Halfdan Sørbye (1994). Penetration of carcinogens into normal and damaged gastric mucosa. (external link)
• Hege Elvebakken; Halfdan Sørbye; Eva Hofsli et al. (2023). High-grade digestive neuroendocrine neoplasms. Impact of genetic alterations and morphologicalcharacteristics on outcome of first-line palliative chemotherapy. (external link)

Research report

• Morten Aaserud; Ivar Sønbø Kristiansen; Aileen Rae Neilson et al. (2007). Helseøkonomisk evaluering av bevacizumab ved metastatisk kolorektalcancer. (external link)

See a complete overview of publications in NVA.