My research projects are focused on understanding cellular signaling (phosphorylation) and can be divided in four topics.

-          Basal research understanding signaling node cascade.

-          Aberrant signaling pattern in chronic and acute myeloid leukemia.

-          Phospho-signaling and hematologic pattern to immunologic response.

-          Mass Cytometry – a new instrument analyzing over 40 parameters in a single cell manner.                      

I have shown that analyzing in vivo patient whole blood, the change in the signaling pattern shortly after start a new treatment regime reflects the drug that is given. Using this methodology I’m involved in several cancer sub-studies - local and international.

Monitoring signaling patterns in patients starting a new treatment is likely to be of important for patient progress, early drug evaluation, as well as increased understanding of complex diseases.