Juvenile idiopathic arthritis (JIA) is currently the most accepted term to describe various types of chronic arthritis in children. By the second half of the nineteenth century, science was beginning to move and Sir Georg Frederic Still and Mayer S. Diamantberger were the first pediatricians who characterized chronic arthritis in children and its progressive destruction (1,2). Until now the etiology and pathogenesis of juvenile idiopathic arthritis is complex and not completely understood. My project is tight connected with The Norwegian JIA Study (NorJIA) (http://norjia.com/index.html) , a prospective, observational multicenter study of children with JIA and healthy controls (for oral issues only), attending the university clinics in Bergen, Tromsø and Trondheim. There will be a special focus on the temporomandibular joints (TMJs) with extensive imaging (MRI 3Tesla, ultrasound, OPG, CEPH, Bitewings and CBCT) and clinical examination, aiming at establishing scoring systems for active and chronic disease.

The overall goal of my study is to explore correlations between clinical pain and diagnostic imaging markers of children and adolescence with JIA and to find diagnostic tools for early detection of children/adolescence that have temporomandibular joint (TMJ) involvements and to develop a multidisciplinary investigation method to avoid under- diagnosing and under- treatment. The supervisors for the Phd project are main supervisor Annika Rosén, Professor and specialist in Oral and Maxillofacial surgery; co-supervisor Marit Slåttelid Skeie, Associate professor and specialist in Pedodontics and co-supervisor Karen Rosendahl, Professor and specialist in Radiology and head of the Multicenterstudy NORJIA.

1.          Still GF. On a form of chronic joint disease in children. 1896. Clin Orthop Relat Res [Internet]. 1990;(259):4–10. Available from: https://www.ncbi.nlm.nih.gov/pubmed/2208872

2.          Kaiser H. [Mayer S. Diamantberger (1864-1944). The first person to describe juvenile chronic arthritis]. Z Rheumatol [Internet]. 2009;68(3):264–6, 268–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19288119

Academic article

• Cetrelli, Lena Elisabet; Lundestad, Anette; Gil, Elisabeth Grut et al. (2024). Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis—an explorative cross-sectional study. (external link)
• Augdal, Thomas Angell; Angenete, Oskar W; Shi, Xie-Qi et al. (2023). Cone beam computed tomography in the assessment of TMJ deformity in children with JIA: repeatability of a novel scoring system. (external link)
• Halbig, Josefine Mareile; Jönsson, Birgitta; Gil, Elisabeth Grut et al. (2023). Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis – a prospective multicenter cohort study. (external link)
• Cetrelli, Lena Elisabet; Bletsa, Athanasia; Lundestad, Anette et al. (2022). Vitamin D, oral health, and disease characteristics in juvenile idiopathic arthritis: a multicenter cross-sectional study. (external link)
• Gil, Elisabeth Grut; Skeie, Marit Slåttelid; Halbig, Josefine Mareile et al. (2022). Oral health-related quality of life in 4-16-year-olds with and without juvenile idiopathic arthritis. (external link)
• Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Lie, Stein Atle et al. (2022). Dental plaque and gingival bleeding in adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis. (external link)
• Fischer, Johannes Maria; Halbig, Josefine Mareile; Augdal, Thomas Angell et al. (2022). Observer agreement of imaging measurements used for evaluation of dentofacial deformity in juvenile idiopathic arthritis. (external link)
• Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Lie, Stein Atle et al. (2021). Dental caries in children and adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis. (external link)
• Fischer, Johannes Maria; Augdal, T.A.; Angenete, O. et al. (2021). In children and adolescents with temporomandibular disorder assembled with juvenile idiopathic arthritis - no association were found between pain and TMJ deformities using CBCT. (external link)
• Fischer, Johannes Maria; Skeie, Marit Slåttelid; Rosendahl, Karen et al. (2020). Prevalence of temporomandibular disorder in children and adolescents with juvenile idiopathic arthritis – a Norwegian cross- sectional multicentre study. (external link)

Academic lecture

• Fischer, Johannes Maria; Augdal, Thomas Angell; Angenete, Oskar W et al. (2020). Localized pain and CBCT features of the temporomandibular joint in patients with Juvenile Idiopathic Arthritis. Preliminary results.. (external link)
• Fischer, Johannes Maria; von Wangenheim Marti, Larissa; Grut Gil, Elisabeth et al. (2017). Prevalence of TMD in children with juvenile idiopathic arthritis(JIA)- a preliminary report from a multicenter study.. (external link)

Poster

• Fischer, Johannes Maria; Augdal, Thomas; Agenete, Oskar et al. (2020). Localized pain and CBCT features of the temporomandibular joint in patients with Juvenile Idiopathic Arthritis - Preliminary results. (external link)
• Gil, Elisabeth Grut; Skeie, Marit Slåttelid; Luukko, Keijo et al. (2020). Oral Health Related Quality of Life in Juvenile Idiopathic Arthritis. (external link)
• Fischer, Johannes Maria; Gil, Elisabeth Grut; Skeie, Marit Slåttelid et al. (2019). Prevalence of Temporomandibular Disorder in Children and Adolescents with Juvenile Idiopathic Arthritis – A Norwegian Multicenter Study. (external link)
• Gil, Elisabeth Grut; Åstrøm, Anne Nordrehaug; Fischer, Johannes Maria et al. (2019). Perceived dental attractiveness in children and adolescents with and without Juvenile Idiopathic Arthritis . (external link)
• Fischer, Johannes Maria; von Wangenheim Marti, Larissa; Grut Gil, Elisabeth et al. (2018). Prevalence of Temporomandibular Disorder in Children and Adolescents with Juvenile Idiopathic arthritis - Preliminary Data from a Norwegian Multicenter Study . (external link)

Abstract

• Cetrelli, Lena Elisabet; Gil, Elisabeth Grut; Lundestad, Anette et al. (2020). Serum Vitamin D and Caries in Juvenile Idiopathic Arthritis. . (external link)

Academic literature review

• Skeie, Marit Slåttelid; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet et al. (2019). Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and meta-analysis. (external link)

See a complete overview of publications in Cristin.