Research
I hold a Bachelor’s in Dentistry from University of Khartoum, Sudan and a Ph.D. in Tissue Engineering from the University of Bergen, where I was awarded Faculty of Medicine’s best PhD prize. I investigated the efficacy and immune responses of functionalised bioactive scaffolds in delivering growth factors for bone tissue engineering. I continued as a post doctor in the Tissue Engineering group at UiB with a research fellowship at Department of Applied Oral Sciences at The Forsyth Institute and Harvard School of Dental Medicine, USA. My research efforts were recognised by the Meltzer Prize for Outstanding Young Researchers in 2020.
Currently, my research is centred on immune-driven tissue regeneration. My overarching goal is to create conducive environments for the regeneration of injured tissues, with a specific focus on understanding and harnessing the impact of the immune system on regeneration, particularly in the realm of stem-cell based bone regeneration. Employing a combination of in vitro and in vivo translational methodologies, we strive to unravel insights into the intricate crosstalk between immune cells and stem cells within the context of regenerative engineering. Additionally, we aim to use this knowledge to promote regeneration in compromised healing and to design regenerative biomaterials with osteoimmunomodulatory properties.
Outreach
What Happens in a Bone Tissue Engineering Lab? - YouTube - A tour briefly showing how we use stem cells to engineer bone in a research lab at the University of Bergen - Department of Clinical Dentistry - (Tissue Engineering Research Group). The content of the video is created with the aim of targeting high school students and the general public audience.
Publications
Academic article
- Hassan, Mohamad Nageeb Abdelaziz; Eltawila, Ahmed M.; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2024). Correlation between Ca Release and Osteoconduction by 3D-Printed Hydroxyapatite-Based Templates. (external link)
- Aydin, Mehmet Serhat; Marek, Nora Chiara; Luciani, Theo Jean et al. (2024). Impact of Porosity and Stiffness of 3D Printed Polycaprolactone Scaffolds on Osteogenic Differentiation of Human Mesenchymal Stromal Cells and Activation of Dendritic Cells. (external link)
- Ali, Hassan Abdel-Raouf Abdel-Wahab; Suliman, Salwa; Osman, Tarig Al-Hadi et al. (2023). Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues. (external link)
- Das, Ridhima; Harper, Lisa; Kitajima, Kayoko et al. (2023). Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction. (external link)
- Rana, Neha; Suliman, Salwa; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid et al. (2022). Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization. (external link)
- Shanbhag, Siddharth; Rana, Neha; Suliman, Salwa et al. (2022). Influence of Bone Substitutes on Mesenchymal Stromal Cells in an Inflammatory Microenvironment. (external link)
- Suliman, Salwa; Mieszkowska, Anna; Folkert, Justyna et al. (2022). Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration. (external link)
- Hassan, Mohamad Nageeb Abdelaziz; Yassin, Mohammed Ahmed ; Eltawila, Ahmed Maher et al. (2022). Contact osteogenesis by biodegradable 3D-printed poly(lactide-co-trimethylene carbonate). (external link)
- Shanbhag, Siddharth; Elsebahy, Ahmad Rashad; Helgeland Nymark, Ellen et al. (2021). Spheroid Coculture of Human Gingiva-Derived Progenitor Cells With Endothelial Cells in Modified Platelet Lysate Hydrogels. (external link)
- Shanbhag, Siddharth; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2021). Bone regeneration in rat calvarial defects using dissociated or spheroid mesenchymal stromal cells in scaffold-hydrogel constructs. (external link)
- Rana, Neha; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2021). Systemic and local innate immune responses to surgical co-transplantation of mesenchymal stromal cells and biphasic calcium phosphate for bone regeneration. (external link)
- Alvarez, Carla; Abdalla, Henrique; Suliman, Salwa et al. (2021). RvE1 Impacts the Gingival Inflammatory Infiltrate by Inhibiting the T Cell Response in Experimental Periodontitis. (external link)
- Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2021). Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs. (external link)
- Shanbhag, Siddharth; Suliman, Salwa; Bolstad, Anne Isine et al. (2020). Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering. (external link)
- Mohamed Ali, Hiba; Mustafa , Manal ; Suliman, Salwa et al. (2020). Inflammatory mediators in saliva and gingival fluid of children with congenital heart defect. (external link)
- Shanbhag, Siddharth; Mohamed Ahmed, Samih; Lunde, Turid Helen Felli et al. (2020). Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering. (external link)
- Alvarez, Carla; Suliman, Salwa; Almarhoumi, Rawan et al. (2020). Regulatory T cell phenotype and anti-osteoclastogenic function in experimental periodontitis. (external link)
- Weigel, Tobias; Schmitz, Tobias; Jannasch, Maren et al. (2019). Session 9: Biomaterials -Elektrospinning. (external link)
- Suliman, Salwa; Ali, Hassan Mohamed Abdel-Raouf; Karlsen, Tommy Aleksander et al. (2019). Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells. (external link)
- Zhuoyuan, Zhang; Gao, Zhenjie; Rajthala, Saroj et al. (2019). Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma associated fibroblasts. (external link)
- Shanbhag, Siddharth; Suliman, Salwa; Pandis, Nikolaos et al. (2019). Cell therapy for orofacial bone regeneration: A systematic review and meta‐analysis. (external link)
- Elsebahy, Ahmad Rashad Saad Mohamed; Suliman, Salwa; Mustafa , Manal et al. (2019). Inflammatory responses and tissue reactions to wood-Based nanocellulose scaffolds. (external link)
- Landolt, Lea Zoe; Furriol, Jessica; Babickova, Janka et al. (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. (external link)
- Munir, Arooj; Døskeland, Anne ; Avery, Steven J et al. (2019). Efficacy of copolymer scaffolds delivering human demineralised dentine matrix for bone regeneration . (external link)
- Mohamed-Ahmed, Samih ; Fristad, Inge; Lie, Stein Atle et al. (2018). Adipose-derived and bone marrow mesenchymal stem cells: a donor-matched comparison. (external link)
- Weigel, Tobias; Schmitz, Tobias; Pfister, Tobias et al. (2018). A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro. (external link)
- Suliman, Salwa; Mustafa, Kamal Babikeir Eln; Krueger, Anke et al. (2016). Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes. (external link)
- Suliman, Salwa; Sun, Yang; Pedersen, Torbjørn Østvik et al. (2016). In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2. (external link)
- Suliman, Salwa; Parajuli, Himalaya; Sun, Yang et al. (2016). Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds. (external link)
- Suliman, Salwa; Xing, Zhe; Wu, X et al. (2015). Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo. (external link)
- Costea, Daniela Elena; Hills, Allison; Osman, Amani Hamza Ali et al. (2013). Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma. (external link)
Feature article
Errata
- Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2022). Corrigendum: Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs (Front. Bioeng. Biotechnol., (2021), 9, (783468), 10.3389/fbioe.2021.783468). (external link)
- Alvarez, Carla; Abdalla, Henrique; Suliman, Salwa et al. (2022). Corrigendum: RvE1 Impacts the Gingival Inflammatory Infiltrate by Inhibiting the T Cell Response in Experimental Periodontitis (Front. Immunol., (2021), 12, 664756, 10.3389/fimmu.2021.664756). (external link)
Academic lecture
- Rana, Neha; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub et al. (2021). Systemic monocyte-macrophage response to co-transplanting mesenchymal stromal cells and biphasic calcium phosphate biomaterial for bone regeneration. (external link)
- Suliman, Salwa; Costea, Daniela Elena; Mustafa, Kamal Babikeir Eln (2015). Development of a novel scaffold stimulating stem cells growth, differentiation and bone regeneration. (external link)
- Costea, Daniela Elena; Hills, Allison; Osman, Amani Hamza Ali et al. (2015). Different subsets of carcinoma-associated fibroblasts promote oral carcinoma cell invasion by distinct mechanisms.. (external link)
- Parajuli, Himalaya; Sapkota, Dipak; Suliman, Salwa et al. (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squamous cell carcinoma behaviour. (external link)
Doctoral dissertation
- Shanbhag, Siddharth; Mustafa, Kamal Babikeir Elnour; Suliman, Salwa et al. (2020). Xeno-free 3D Culture of Mesenchymal Stromal Cells for Bone Tissue Engineering. (external link)
- Suliman, Salwa; Mustafa, Kamal Babikeir Eln (2015). Bioactive copolymer scaffolds for bone tissue engineering. Efficacy and host response. (external link)
- Suliman, Salwa; Mustafa, Kamal Babikeir Eln; Costea, Daniela Elena et al. (2015). Bioactive copolymer scaffolds for bone tissue engineering. Efficacy and host response.. (external link)
Poster
- Rana, Neha; Suliman, Salwa; Shanbhag, Siddharth et al. (2019). Effect of human platelet lysate on rat mesenchymal stem cells for bone regeneration – an in vitro study (POSTER). (external link)
- Ahmed, Samih; Fristad, Inge; Yassin, Mohammed Ahmed et al. (2018). Adipose-Derived Stem Cells for Bone Tissue Engineering. (external link)
- Shanbhag, Siddharth; Ahmed, Samih; Suliman, Salwa et al. (2018). Comparison of donor matched human bone marrow- and adipose-derived mesenchymal stem/stromal cells in Xeno-free conditions.. (external link)
- Shanbhag, Siddharth; Ahmed, Samih; Suliman, Salwa et al. (2018). Characterization of Human Gingiva- and PDL-derived Progenitor Cells in 3-D Xeno-free Conditions. . (external link)
- Suliman, Salwa Mustafa Nourelhuda; Parajuli, Himalaya; McCormack, Emmet et al. (2013). A novel model: Microenvironmentally-induced carcinogenesis for screening bone regeneration scaffolds. (external link)
Academic literature review
- Hassan, Mohamad Nageeb; Yassin, Mohammed Ahmed; Suliman, Salwa et al. (2019). The bone regeneration capacity of 3D-printed templates in calvarial defect models: A systematic review and meta-analysis. (external link)
- Shanbhag, Siddharth; Stavropoulos, Andreas; Suliman, Salwa et al. (2017). Efficacy of humanized Mesenchymal stem cell cultures for bone tissue engineering: a systematic review with a focus on platelet derivatives. (external link)
Projects
2021 - 2025 (Principal Investigator) Immune-driven tissue regeneration (STEMreg) funded by Trond Mohn Foundation Starting Grant: 19.2 million NOK
2021 - 2026 (Principal Investigator) Harnessing regulatory T cells to enhance the efficacy of mesenchymal stem cell-based bone regeneration funded by Research Council of Norway, Young Researcher Talent grant: 8 million NOK