Una Ørvim Sølvik
Position
Associate Professor
Affiliation
Research
Leader of the research group Work, Health and gender and affiliated with the research group SMIL
My main research interests:
- Women's health
- Menopause
- Laboratory medisin
- Diabetes
- Coagulation - INR
- Self control of anticoagulant treatment
- Analytical quality control
From 2023, Sølviks research is specifically focused on women, menopause, and work:
Every year, 27,500 Norwegian women enter menopause, and of these, approximately 30% will experience significant health issues that reduce their quality of life and work capacity. These health issues can range from depression, musculoskeletal pain, sleep problems, headaches, general fatigue, reduced lung capacity, to extreme hot flashes. These symptoms are often classified as nonspecific and contribute significantly to women's sick leave and disability pension.
There is limited research on women's menopause and limited knowledge among women themselves and in healthcare services. Lack of knowledge may result in women's symptoms not being associated with menopause and thus being diagnosed, treated, and medicated as nonspecific women's issues that women must live with.
The Women's Health Committee's report (NOU 2023: 5) highlights the need for more research to determine the role menopausal symptoms play in women's drop-out from the workforce at this age. Furthermore, there is a need for more research on the impact of menopause on women's physical and mental health, and how menopause is experienced by women in different socioeconomic positions. There is also a need for increased knowledge about the relationship between menopause and women's sick leave and exit from the workforce.
Teaching
Associated with Section for Health Sciences and Teaching group leader for Master's in Health and Society
Associated with master in Health and Society and Masters in Health Science.
Member of the group for teaching group leaders, Department of Global Public Health and Primary Care
Associated with Program committee for Master's in health sciences, IGS, UiB
Course coordinator Quantitative research methods, 5 ECTS (HELSAM303) and Quantitative research methods and traditions, 10 ECTS (HELSAM305)
Coordinator for Masters in Health Science, radiographer and biomedical laboratory scientists
Publications
Lecture
Academic lecture
Academic article
- Sølvik, Una Ørvim; Cooper, John; Løvaas, Karianne Fjeld et al. (2024). A register-based study describing time trends in risk factor control and serious hypoglycaemia together with the effects of starting continuous glucose monitoring in people with type 1 diabetes in Norway. (external link)
- Risøy, Aslaug Johanne; Kjome, Reidun Lisbet Skeide; Sandberg, Sverre et al. (2023). Diabetes risk assessments and HbA1c-measurements in community pharmacies. (external link)
- Madsen, Tone Vonheim; Cooper, John; Carlsen, Siri et al. (2023). Intensified follow-up of patients with type 1 diabetes and poor glycaemic control: A multicentre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults. (external link)
- Gidske, Gro; Sandberg, Sverre; Fauskanger, Pernille Kjeilen et al. (2023). Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the biases found. (external link)
- Hare, Lisa; Hetlevik, Anette; Yogarajan, Rochini et al. (2021). Type 2-diabetes i fastlegepraksis – en fokusgruppestudie. (external link)
- Risøy, Aslaug Johanne; Kjome, Reidun Lisbet Skeide; Svensberg, Karin et al. (2020). Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies – A focus-group study. (external link)
- Sølvik, Una Ørvim; Boija, Elisabet Eriksson; Ekvall, Sara et al. (2020). Performance and user-friendliness of the rapid antigen detection tests QuickVue Dipstick Strep A test and DIAQUICK Strep A Blue Dipstick for pharyngotonsillitis caused by Streptococcus pyogenes in primary health care. (external link)
- Sølvik, Una Ørvim; Løkkebø, Elisabeth Sellevoll; Kristoffersen, Ann-Helen et al. (2019). Quality of warfarin therapy and quality of life are improved by self-management for two years. (external link)
- Bukve, Tone; Sandberg, Sverre; Vie, Wenche Sletbakk et al. (2019). Commutability of a whole-blood external quality assessment material for point-of-care C-reactive protein, glucose, and hemoglobin testing. (external link)
- Aarsand, Aasne Karine; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar et al. (2018). The EuBIVAS: Within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin, and glucose. (external link)
- Sølvik, Una Ørvim; Risøy, Aslaug Johanne; Kjome, Reidun Lisbet Skeide et al. (2018). Quality control of Norwegian pharmacy HbA1c testing: a modest beginning. (external link)
- Risøy, Aslaug Johanne; Kjome, Reidun Lisbet Skeide; Sandberg, Sverre et al. (2018). Risk assessment and HbA1c measurement in Norwegian community pharmacies to identify people with undiagnosed type 2 diabetes ? A feasibility study. (external link)
- Carobene, Anna; Marino, Irene; Coskun, Abdurrahman et al. (2017). The EuBIVAS project: within- and between-subject biological variation data for serum creatinine using enzymatic and alkaline picrate methods and implications for monitoring. (external link)
- Carobene, Anna; Røraas, Thomas; Sølvik, Una Ørvim et al. (2017). Biological variation estimates obtained from 91 healthy study participants for 9 enzymes in serum. (external link)
- Sølvik, Una Ørvim; Bjelkarøy, Wenche Iren; Berg, Kari van den et al. (2017). Intensive educational efforts combined with external quality assessment improve the preanalytical phase in general practitioner offices and nursing homes. (external link)
- Carobene, Anna; Strollo, Marta; Jonker, Neils et al. (2016). Sample collections from healthy volunteers for biological variation estimates' update: A new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine. (external link)
- Andreassen, Lillan Mo; Kjome, Reidun Lisbet Skeide; Sølvik, Una Ørvim et al. (2016). The potential for deprescribing in care home residents with Type 2 diabetes. (external link)
- Andreassen, Lillan Mo; Granås, Anne Gerd; Sølvik, Una Ørvim et al. (2016). 'I try not to bother the residents too much' - the use of capillary blood glucose measurements in nursing homes. (external link)
- Sølvik, Una Ørvim; Løkkebø, Elisabeth Sellevoll; Kristoffersen, Ann-Helen et al. (2015). Egenkontroll av warfarinbehandling. (external link)
- Sølvik, Una Ørvim; Røraas, Thomas; Petersen, Per Hyltoft et al. (2014). The influence of coagulation factors on the in-treatment biological variation of international normalized ratio for patients on warfarin. (external link)
- Andreassen, Lillan Mo; Sandberg, Sverre; Kristensen, Gunn Berit Berge et al. (2014). Nursing home patients with diabetes: Prevalence, drug treatment and glycemic control. (external link)
- Sølvik, Una Ørvim; Røraas, Thomas Helge; Christensen, Nina Gade et al. (2013). Diagnosing Diabetes Mellitus: Performance of Hemoglobin A(1c) Point-of-Care Instruments in General Practice Offices. (external link)
- Stavelin, Anne; Petersen, Per Hyltoft; Sølvik, Una Ørvim et al. (2013). External quality assessment of point-of-care methods: model for combined assessment of method bias and single-participant performance by the use of native patient samples and noncommutable control materials. (external link)
- Sølvik, Una Ørvim; Røraas, Thomas Helge; Petersen, Per Hyltoft et al. (2012). Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. (external link)
- Sølvik, Una Ørvim; Petersen, Per Hyltoft; Monsen, Grete et al. (2010). Discrepancies in International Normalized Ratio Results between Instruments: A Model to Split the Variation into Subcomponents. (external link)
- Stavelin, Anne; Petersen, Per Hyltoft; Sølvik, Una Øvrim et al. (2009). Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. (external link)
- Stavelin, Anne; Petersen, Per Hyltoft; Sølvik, Una Øvrim et al. (2009). Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. (external link)
- Sølvik, Una Øvrim; Stavelin, Anne; Christensen, Nina Gade et al. (2006). External quality assessment of prothrombin time: The split-sample model compared with external quality assessment with commercial control material. (external link)
- Sølvik, Una Øvrim (2006). External quality assessment of prothrombin time: the split-sample model compared with external quality assessment with commercial control material. (external link)
- Sølvik, Una Ørvim (1994). The effect of serum amyloid protein A fragment-SAA25-76 on blood platelet aggregation. (external link)
- Roald, Helge Einar; Sølvik, Una Ørvim; Bakken, Inger Johanne et al. (1994). Modulation of thrombotic responses in moderately stenosed arteries by cigarette smoking and aspirin ingestion. (external link)
Doctoral dissertation
Letter to the editor
- Gidske, Gro; Sølvik, Una Ørvim; Sandberg, Sverre et al. (2018). Hemolysis interference studies: Freeze method should be used in the preparation of hemolyzed samples. (external link)
- Løkkebø, Elisabeth Sellevoll; Kristoffersen, Ann-Helen; Stavelin, Anne et al. (2017). Effect of dabigatran treatment at therapeutic levels on point-of-care international normalized ratio (INR). (external link)
- Sølvik, Una Ørvim; Risa, Marianne; Jacobsen, Camilla Eide et al. (2015). Performance of 10 systems for self-monitoring of blood glucose by trained healthcare professionals and in the hands of the users. (external link)
Poster
- Risøy, Aslaug Johanne; Kjome, Reidun Lisbet Skeide; Sandberg, Sverre et al. (2016). A feasibility study for risk assessment ofType 2 Diabetes (T2D) in pharmacies. (external link)
- Pettersen, Marianne S.; Kjome, Reidun Lisbet Skeide; Sølvik, Una Ørvim (2016). ‘It’s a jungle out there’ - A focus group study about being diagnosed with type 2 diabetes. (external link)
Masters thesis
- Aabel, Ingunn; Østlie, Ingrid Landgraff; Sølvik, Una Ørvim (2013). Rolleutvidelse ved noen bildediagnostiske avdelinger i Norge. (external link)
- Gullien, Randi; Skaane, Per; Sølvik, Una Ørvim (2013). PGMI klassifisering av mammografibilder ved interne og eksterne mamma-radiografer. (external link)
- Bjelkarøy, Wenche Iren; Munkerud, Siri Fauli; Sølvik, Una Ørvim (2013). Er laboratorierutiner og laboratoriekvalitet ved norske sykehjem endret? Har opplæring og oppfølging initiert av Noklus som del av Omsorgsplan 2015 nyttet?. (external link)
- Olsen, Sahar; Sørum, Henning; Tveten, Ann Kristin et al. (2012). Sammenligning av nukleinsyre isoleringsteknikker i forbindelse med etablering av qPCR påvisningsmetode for Borrelia infeksjon. (external link)
- Løkkebø, Elisabeth Sellevoll; Sølvik, Una Ørvim (2011). Trygg antikoagulasjonsbehandling: Pasienter i Norge kan drive egenkontroll av warfarinbehandling. (external link)
- Johnsen Risnes, Lydia; Pedersen, Gustav; Laxdal, Elin Hanna et al. (2011). Tredimensjonale ultralyd volummålinger IN VITRO validering av metode til oppfølging av abdominale aortaaneurismer. (external link)
- Antonsen, Jeanett Hoff; Lundgren, Steinar; Sølvik, Una Ørvim (2011). Strålebehandling til kvinner med brystkreft Endring av venstre ventrikkels ejeksjonsfraksjon (LVEF) gjennom et behandlingsforløp med strålebehandling, målt med den nukleærmedisinske metoden planar MUGA- scan. (external link)
- Vikestad, Kari Gerhardsen; Hofmann, Bjørn M.; Eikefjord, Eli Nina et al. (2011). Videreutdanning i Ultralyd for radiografer I hvilken grad er læringsmålene nådd? En kontrollert prospektiv sammenlignende studie 6 mnd etter endt utdanning. (external link)
- Mæhle, Siri Gun; Eilertsen, Karsten; Sølvik, Una Ørvim (2011). Bildeveiledet stråleterapiVil bruk av konvensjonell stimulator bidra til å minimere systematiske innstillingsavvik, og dermed øke innstillingspresisjonen, sammenlignet med bildeveiledet innstilling på behandlingsapparat?. (external link)
- Berntsen, Astrid; Hofmann, Bjørn M.; Sølvik, Una Ørvim (2010). Utfordringer ved digital bildeteknologi; en kvalitativ studie av radiografers rolle og deres oppfatning av bildekvalitet ved arbeid med digitale røntgenbilder. (external link)
- Therkildsen, Flemming; Ween, Borgny; Sølvik, Una Ørvim (2010). Feltstyrke ved Magnetisk Resonansskanning af håndled og fingrenes led hos pasienter med leddegigt. (external link)
- Frøseth, Trude Camilla Salvesen; Reidunsdatter, Randi Johansen; Sølvik, Una Ørvim (2010). Betydning av pasientleie for tynntarmsdose ved strålebehandling av pasienter med rectumcancer. (external link)
- Nerhus, Kari; Rustad, Pål; Sølvik, Una Ørvim (2010). Hvordan lav og høy temperatur påvirker måling av blodsukker med apparater i bruk av personer med diabetes. (external link)
- Solli, Kjersti; Brattheim, Berit; Sølvik, Una Ørvim et al. (2010). Betydning av behandlingsleie for reproduserbarhet ved strålebehandling av rectumcancer. (external link)
- Gaarder, Mario; Klow, Nils-Einar; Sølvik, Una Ørvim (2010). Deteksjon av tidlige veggforandringer i halsarterier hos barn og unge med type-1 diabetes. (external link)
- Precht, Helle; Hafslund, Bjørg; Mussmann, Bo et al. (2009). Processerings optimering med Canons software -et fantom projekt om dosis besparelse ved anvendelse af Canons nye DR Spectra software på børnefemur undersøgelser. (external link)
- Rambech, Kristin; Frengen, Jomar; Sølvik, Una Ørvim (2009). Strålebehandling av pasienter med brystkreft og bruk av intensitetsmodulert radioterapi (IMRT). (external link)
- Stavelin, Anne Vegard; Pedersen, P.H.; Sølvik, Una Øvrim (2007). Analyse av protrombintid i primærhelsetjenesten - vurdering av analysekvalitet og en evaluering av to kontrollsystem for analytisk kvalitetskontroll ved hjelp av datasimuleringer. (external link)
See a complete overview of publications in Cristin.
Sølvik UØ, Cooper JG, Løvaas KF, Ernes T, Madsen TV, Sandberg S, Ueland GÅ. A register-based study describing time trends 2012-2020 in risk factor control for people with type 1 diabetes in Norway and the effect of starting continuous glucose monitoring on HbA1c. Diabetes Medicine In Press
Risøy AJ, Kjome R, Sandberg S, Sølvik UØ. Diabetes risk assessments and HbA1c-measurements in community pharmacies. Int J Pharm Pract 2023; https://doi.org/10.1093/ijpp/riad055
Gidske G, Sandberg S, Fauskanger P, Pelanti J, Tollånes MC, Solsvik AE, Sølvik UØ, Vie WS, and Stavelin A. Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the biases found. Clin Chem Lab Med 2023 https://doi.org/10.1515/cclm-2023-0532
Madsen TV, Cooper JG, Carlsen S, Løvaas K, Rekdal M, Igland J, Sandberg S, Ueland GÅ, Iversen MM, Sølvik UØ. Intensified follow-up of patients with type 1 diabetes and poor glycaemic control.A multi-centre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults. BMJ Open Quality 2023;12:e002099.
Hare L, Hetlevik A, Yogarajan R, Kjome RLS, Sølvik UØ. Type 2-diabetes i fastlegepraksis – en fokusgruppestudie. Tidsskr Nor Legeforen 2021. doi: 10.4045/tidsskr.20.0623.
Risøy AJ, Kjome, RLS, Svensberg K, Råheim M, Sølvik UØ. Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies: a focus-group study. Research in Social and Administrative Pharmacy 2020. Pharmacists’ experience of a diabetes risk-assessment service and analytical quality control in community pharmacies – A focus-group study - ScienceDirect
Sølvik UØ, Boija EE, Ekvall S, Jabbour A, Breivik AC Nordin G, Sandberg S. Performance and user-friendliness of the rapid antigen detection tests QuickVue Dipstick Strep A test and DIAQUICK Strep A Blue Dipstick for pharyngotonsillitis caused by Streptococcus pyogenes in primary health care. European Journal of Clinical Microbiology and Infectious Diseases 2020 s. 1-10
Kjome RL, Pettersen MS, Råheim M, Sølvik UØ. Being diagnosed with type 2 diabetes – shock, shame and information chaos. A focus group study among persons with type 2 diabetes in Norway.
Sølvik UØ, Løkkebø E, Kristoffersen AH, Brodin E, Averina M, Sandberg S. Quality of warfarin therapy and quality of life are improved by self-management for two years. Thrombosis and Haemostasis 2019;65:791-797. https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0039-1693703.
Bukve T, Sandberg S, Wenche SV, Sølvik U, Christensen NG, Stavelin A. Commutability of a whole-blood external quality assurance material for point-of-care C-reactive protein, glucose, and hemoglobin testing. Clin Chem 2019;65:6 http://clinchem.aaccjnls.org/content/clinchem/early/2019/03/06/clinchem.2018.300202.full.pdf
Aarsand AK, Diaz-Garzon J, Fernandez-Calle P, Guerra E, Locatelli M, Bartlett WA, Sandberg S, Røraas T, Ceriotti F,Sølvik UO, Sylte MS, Coskun A, Serteser M, Unsal I, Tosato F, Plebani M, Jonker N, Barla G and Carobene A. The EuBIVAS: Within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin and glucose. Clin Chem 2018;64:9.
Gidske G, Sølvik UØ, Kristensen GB, Sandberg S. Hemolysis interference studies: Freeze Method should be used in the preparation of hemolyzed samples. Clin Chem Lab Med. 2018; 56:e220–e222.
Sølvik UØ, Risøy AJ, Kjome R, Sandberg S. Quality control of Norwegian Pharmacy HbA1c testing: A modest beginning. J Diab Sci Technol. 2018;12:753–761. http://journals.sagepub.com/eprint/43MUKZ66cs8kvrKKFs2E/full
Risøy AJ, Kjome RLS, Sandberg S, Sølvik UØ.Risk assessment and HbA1c measurement in Norwegian community pharmacies to identify people with undiagnosed type 2 diabetes - a feasibility study. PLOS ONE. 2018;13: e0191316. https://doi.org/10.1371/journal.pone.0191316.
Carobene A, Marino I, Coskun A, Serteser M, Unsal I, Guerra E, Bartlett WA, Sandberg S, Aarsand AK, Sylte MS, Røraas T, Sølvik UO, Fernandez-Calle P, Diaz-Garzon J, Tosato F, Plebani M, Jonker N, Barla G and Ceriotti F on behalf of the European Biological Variation Study of the EFLM Working Group on Biological Variation. The EuBIVAS Project: Within–and Between-Subject Biological Variation Data for Serum Creatinine Using Enzymatic and Alkaline Picrate Methods and Implications for Monitoring. Clin Chem. 2017;63. http://clinchem.aaccjnls.org/content/early/2017/07/12/clinchem.2017.275115
Sølvik UØ, Bjelkarøy WI, van den Berg K, Saga AL, Helle B. Hager HB and Sandberg S. Intensive educational efforts combined with external quality assessment improve the pre-analytical phase in general practitioner offices and nursing homes. Clin Chem Lab Med. 2017;55:1857-1864. DOI 10.1515/cclm-2016-115
Carobene A, Røraas T, Sølvik UO, Sylte MS, Sandberg S, Guerra E, Marino I, Jonker N, Barla G, Bartlett WA, Fernandez-Calle P, Garzon JG, Tosato F, Plebani M, Coskun A, Serteser M, Unsal I, and Ceriotti F. Biological variation estimates obtained from 91 healthy subjects for nine enzymes in serum. On behalf of the European Biological Variation Study (EuBIVAS) of the EFLM working-group on biological variation. Clin Chem 2017;63:1141-1150.
Løkkebø EL, Kristoffersen AH, Stavelin A, Sølvik UØ. Effect of dabigatran treatment at therapeutic levels on Point-of-Care International Normalized Ratio. Clin Chem Lab Med 2016. DOI 10.1515/cclm-2016-0872.
Carobene A, Strollo M, Jonker N, Barla G, Bartlett WA, Sandberg S, Sylte MS, Røraas T, Sølvik UØ, Fernandez-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coşkun A, Serteser M, Unsal I, Ceriotti F. Sample collections from healthy volunteers for biological variation estimates´ update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine. Clin Chem Lab Med 2016. DOI 10.1515/cclm-2016-0035.
Andreassen LM, Kjome RL, Sølvik UØ, HoughtonJ, Desborough JA. The potential for deprescribing in care home residents with Type 2 diabetes. Int J Clin Pharm 2016;38:977-84.
Sølvik UØ, Risa M, JacobsenC, MonsenG, Sandberg S. Performance of ten systems for self-monitoring of blood glucose by trained healthcare professionals and in the hands of the users. Clin Chem 2015;61:772-4.
Sølvik UØ, Løkkebø ES, Kristoffersen AH, Stavelin A, Binder S, Sandberg S. Self-management of warfarin therapy. Tidsskr Nor Legeforening 2015;135:849-53.
Andreassen LM, Kjome RL, Kristensen G, Sølvik UØ, Sandberg S. Nursing home patients with diabetes: Prevalence, drug treatment and glycemic control. Diabetes Res Clin Pr 2014;105:102-9.
Sølvik UØ, Røraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S. The influence of coagulation factors on the in-treatment biological variation of international normalized ratio for patients on warfarin. Scand J Clin Lab Invest 2014;74:470-6.
Sølvik UØ, Røraas T, Christensen NG, Sandberg S. Diagnosing Diabetes Mellitus: Performance of Hemoglobin A1c Point-of-Care Instruments in General Practice Offices. Clin Chem 2013;59:1790-801.
Stavelin A, Petersen PH, Sølvik UØ, Sandberg S. External Quality Assessment of Point-of-Care Methods: Model For Combined Assessment of Method Bias and Single-Participant Performance by the Use of Native Patient Samples and Noncommutable Control Materials. Clin Chem 2013;59:363-71.
Sølvik UØ, Røraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S. Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. Clin Chem Lab Med 2012;50:1611-20.
Sølvik UØ, Petersen PH, Monsen G, Stavelin AV, Sandberg S. Discrepancies in international normalized ratio results between instruments: a model to split the variation into subcomponents. Clin Chem 2010;56:1618-26.
Stavelin A, Petersen PH, Sølvik U, Sandberg S. Internal quality control of prothrombin time in primary care: comparing the use of patient split samples with lyophilised control materials. Thromb Haemost 2009;102:593-600.
Sølvik UØ, Stavelin A, Christensen NG, Sandberg S. External quality assessment of prothrombin time: the split-sample model compared with external quality assessment with commercial control material. Scand J Clin Lab Invest 2006;66:337-49.
Orning L, Fischer PM, Hu CK, Agner E, Engebretsen M, Husbyn M, Petersen LB, Ørvim U, Llinas M, Sakariassen KS. A cyclic pentapeptide derived from the second EGF-like domain of Factor VII is an inhibitor of tissue factor dependent coagulation and thrombus formation. Thromb Haemost 2002;87:13-21.
Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE. Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation 2001;72:1967-73.
Saethre M, Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Platt JL, Mollnes TE. Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies. Xenotransplantation 2002;9:350-8.
Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE. Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation 2001;72:1967-73.
Sølvik UO, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Mollnes TE. C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells. Transplant Proc 2001;33:789-90.
Hagberg IA, Sølvik UØ, Opdahl H, Roald HE, Lyberg T. Inhalation of nitric oxide inhibits ADP-induced platelet aggregation and alpha-granule release. Platelets 1999;10:382-90.
Sakariassen KS, Holme PA, Ørvim U, Barstad RM, Solum NO, Brosstad FR. Shear-induced platelet activation and platelet microparticle formation in native human blood. Thromb Res 1998;92(6 Suppl 2):S33-41.
Ørvim U, Barstad RM, Orning L, Petersen LB, Ezban M, Hedner U, Sakariassen KS.
Antithrombotic efficacy of inactivated active site recombinant factor VIIa is shear dependent in human blood. Arterioscler Thromb Vasc Biol 1997;17:3049-56.
Holme PA, Ørvim U, Hamers MJ, Solum NO, Brosstad FR, Barstad RM, Sakariassen KS. Shear-induced platelet activation and platelet microparticle formation at blood flow conditions as in arteries with a severe stenosis. Arterioscler Thromb Vasc Biol 1997;17:646-53.
Barstad RM, Buchmann MS, Hamers MJ, Orning L, Ørvim U, Stormorken H, Sakariassen KS. Effects of ionic and nonionic contrast media on endothelium and on arterial thrombus formation. Acta Radiol 1996;37:954-61.
Ørvim U, Barstad RM, Stormorken H, Brosstad F, Sakariassen KS. Immunologic quantification of fibrin deposition in thrombi formed in flowing native human blood. Br J Haematol 1996;95:389-98.
Barstad RM, Ørvim U, Hamers MJ, Tjønnfjord GE, Brosstad FR, Sakariassen KS.
Reduced effect of aspirin on thrombus formation at high shear and disturbed laminar blood flow. Thromb Haemost 1996;75:827-32.
Ørvim U, Barstad RM, Vlasuk GP, Sakariassen KS. Effect of selective factor Xa inhibition on arterial thrombus formation triggered by tissue factor/factor VIIa or collagen in an ex vivo model of shear-dependent human thrombogenesis. Arterioscler Thromb Vasc Biol 1995;15:2188-94.
Ørvim U, Roald HE, Stephens RW, Roos N, Sakariassen KS. Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow conditions. Arterioscler Thromb 1994;14:1976-83.
Syversen PV, Saeter U, Cunha-Ribeiro L, Ørvim U, Sletten K, Husby G, Sakariassen KS. The effect of serum amyloid protein A fragment-SAA25-76 on blood platelet aggregation. Thromb Res 1994;76:299-305.
Roald HE, Ørvim U, Bakken IJ, Barstad RM, Kierulf P, Sakariassen KS. Modulation of thrombotic responses in moderately stenosed arteries by cigarette smoking and aspirin ingestion. Arterioscler Thromb 1994;14:617-21.
Projects
KLAR - Women's health, menopause and working life. From 2023, I have been engaged in developing a project where menopause and work are at the centre. There is little research into how health problems during women's menopause can affect work participation, and varying knowledge of the topic among women themselves and in health care. Lack of knowledge can lead to women's complaints not being associated with menopause and thus being diagnosed, treated and medicated as non-specific women's complaints. These complaints are the most common reasons for women's sickness absence mid-life. The project is funded by Grig Foundation
Patients' experiences with self-management of anticoagulation treatment Studies have shown that patients who engage in self-monitoring of Marevan treatment (measuring the INR and dosing Marevan themselves) have fewer clinical events compared to conventional treatment by the GP. In Norway, approx. 2500 patients have been trained to self-management the approx. 25,000 who use Marevan. It is therefore desirable that more suitable patients are trained to self-management of anticoagulation treatment so that they receive the best possible treatment. The purpose of the project is to gain additional knowledge about the patients' experiences with self-management of anticoagulation treatment. More specifically, we want to know what motivates the patients to perform self-management, what advantages and challenges they face.