- heidrun.vethe@uib.no
- Visitor address
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Gades lab for Patologi Sentralblokken, 2. etg. Haukeland Universitetssjukehus
5021 Bergen - Postal address
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P.O. Box 7804NO-5020 BergenNorway
Research
I am a molecular biologist, with a PhD from University of Bergen on stem cell research and diabetes. My current research work focuses on identifying protein biomarkers and novel targets in aggressive breast cancer, with special emphasis on tumor cell plasticity and nerve involvement in the tumor microenvironment. To study the interaction between cancer cells and nerves, we use a combination of methods including mass spectrometry-based proteomics, imaging mass cytometry and cell models.
Publications
Professional article
Academic article
- Yngvild Bjørlykke; Anne Mette Søviknes; Laurence Hoareau et al. (2019). Reprogrammed cells display distinct proteomic signaturesAssociated with colony morphology variability. (external link)
- Kenichiro Furuyama; Simona Chera; Leon van Gurp et al. (2019). Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (external link)
- Kenneth Finne; Hans-Peter Marti; Sabine Maria Leh et al. (2016). Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. (external link)
- Yngvild Bjørlykke; Heidrun Vethe; Marc Vaudel et al. (2014). Carboxyl-ester lipase maturity-onset diabetes of the young disease protein biomarkers in secretin-stimulated duodenal juice. (external link)
- Astrid Guldbrandsen; Heidrun Vethe; Yehia Mohamed Mokhtar Farag et al. (2014). In-depth characterization of the cerebrospinal fluid (CSF) proteome displayed through the CSF proteome resource (CSF-PR). (external link)
- Magnus Berle; Luiza Ghila; Heidrun Vethe et al. (2018). Novel protein signatures suggest progression to muscular invasiveness in bladder cancer. (external link)
- Luiza Ghila; Yngvild Bjørlykke; Thomas Aga Legøy et al. (2020). Bioinformatic analyses of miRNA-mRNA signature during hiPSC differentiation towards insulin-producing cells upon HNF4α mutation. (external link)
- Thomas Aga Legøy; Andreas Frøslev Mathisen; Zaidon Salim et al. (2020). In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism. (external link)
- Ann Cathrine Kroksveen; Jacob D. Jaffe; Elise Aasebø et al. (2015). Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis. (external link)
- Thomas Aga Legøy; Luiza Ghila; Heidrun Vethe et al. (2019). In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. (external link)
- Tomoko Okuyama; Jun Shirakawa; Kazuki Tajima et al. (2020). Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor. (external link)
- Magnus Berle; Kjersti Elvestad Hestetun; Heidrun Vethe et al. (2022). Mapping Proteome Changes in Microsatellite Stable, Recurrent Colon Cancer Reveals a Significant Immune System Signature. (external link)
- Thomas Aga Legøy; Heidrun Vethe; Shadab Abadpour et al. (2020). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. (external link)
- Elisabeth Wik; Sura Mohammed Aziz; Heidrun Vethe et al. (2022). Neurogenesis and angiogenesis are associated features of aggressive breast cancer. (external link)
- Ole Vidhammer Bjørnstad; Manuel Carrasco Fernandez; Kenneth Finne et al. (2024). Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model. (external link)
- Ann Cathrine Kroksveen; Elise Aasebø; Heidrun Vethe et al. (2013). Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM. (external link)
- Manoj K. Gupta; Heidrun Vethe; Samir Softic et al. (2020). Leptin receptor signaling regulates protein synthesis pathways and neuronal differentiation in pluripotent stem cells. (external link)
- Heidrun Vethe; Luiza Ghila; Magnus Berle et al. (2019). The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation. (external link)
- Heidrun Vethe; Thomas Aga Legøy; Shadab Abadpour et al. (2019). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. (external link)
- Larry Sai Weng Loo; Heidrun Vethe; Andreas Alvin Purnomo Soetedjo et al. (2019). Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors. (external link)
- Manuel Carrasco Fernandez; Ole Vidhammer Bjørnstad; Heidrun Vethe et al. (2025). Adrenergic signals influence proteomic responses in breast cancer cells. (external link)
- Heidrun Vethe; Yngvild Bjørlykke; Luiza Ghila et al. (2017). Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. (external link)
- Silje Kjølle; Kenneth Finne; Even Birkeland et al. (2023). Hypoxia induced responses are reflected in the stromal proteome of breast cancer. (external link)
- Ole Vidhammer Bjørnstad; Manuel Carrasco Fernandez; Kenneth Finne et al. (2024). Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model. (external link)
- Kenneth Finne; Heidrun Vethe; Trude Skogstrand et al. (2014). Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats. (external link)
- Heidrun Vethe; Kenneth Finne; Trude Skogstrand et al. (2015). Distinct protein signature of hypertension-induced damage in the renal proteome of two-kidney-one-clip (2K1C) rat model. (external link)