Academic article
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Helge Wiig; D Keskin; Raghu Kalluri
(2010). Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis og lymphatic function. (external link)
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Helge Wiig; L. Sibley; M. Decarlo
et al. (1991). Sampling interstitial fluid from rat skeletal muscle by intermuscular wicks. (external link)
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Helge Wiig; Per Ole Iversen
(2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
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Torbjørn Nedrebø; Rolf Kåre Reed; Roland Jonsson
et al. (2004). Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats. (external link)
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Helge Wiig; Ellen Berggreen; Bengt Åge Sørby Borge
et al. (2004). Demonstration of altered signaling responses in bone marrow extracellular fluid during increased hematopoiesis in rats using a centrifugation method. (external link)
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Helge Wiig; Agnes Schroeder; Wolfgang Neuhofer
et al. (2013). Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. (external link)
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Panagiota Papadakou; Athanasia Bletsa; Mohammed Ahmed Alamin Yousif Yassin
et al. (2017). Role of Hyperplasia of Gingival Lymphatics in Periodontal Inflammation. (external link)
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Øyvind Sverre Svendsen; Malgorzata Barczyk; Svetlana Popova
et al. (2009). The alpha 11 beta 1 integrin has a mechanistic role in control of interstitial fluid pressure and edema formation in inflammation. (external link)
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David Michael Wright; Helge Wiig; C P Winlove
et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
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Alf Hartvig Øien; Helge Wiig
(2016). Electrostatic, elastic and hydration-dependent interactions in dermis influencing volume exclusion and macromolecular transport. (external link)
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W. B. Zhang; Knut Aukland; T. Lund
et al. (2000). Distribution of interstitial fluid pressure and fluid volumes in hind-limb skin of rats: relation to meridians?. (external link)
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Daniela Negrini; Olav Tenstad; Helge Wiig
(2003). Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique. (external link)
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Linda EB Stuhr; Alison Reith; Sigrid Lepsøe
et al. (2003). Fluid pressure in human dermal fibroblast aggregates measured with micropipettes. (external link)
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Christina Gyenge; Olav Tenstad; Helge Wiig
(2003). In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle. (external link)
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Tine Veronica Karlsen; Tore Reikvam; Anne Tofteberg
et al. (2017). Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration. (external link)
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Eli Sihn Samdal Steinskog; Solfrid Johanne Sagstad; Marek Wagner
et al. (2016). Impaired lymphatic function accelerates cancer growth. (external link)
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Christian Hinze; Janett Ruffert; Katharina Walentin
et al. (2017). GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation. (external link)
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Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang
et al. (2018). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
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Eystein Oveland; Tine Veronica Karlsen; Hanne Haslene-Hox
et al. (2012). Proteomic Evaluation of Inflammatory Proteins in Rat Spleen Interstitial Fluid and Lymph during LPS-Induced Systemic Inflammation Reveals Increased Levels of ADAMST1. (external link)
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Daniela Negrini; Olav Tenstad; Alberto Passi
et al. (2006). Differential degradation of matrix proteoglycans and edema development in rabbit lung. (external link)
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Helge Wiig; Olav Tenstad; Joel L. Bert
(2005). Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro. (external link)
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Hanne Haslene-Hox; Olav Tenstad; Helge Wiig
(2013). Interstitial fluid-a reflection of the tumor cell microenvironment and secretome. (external link)
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Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig
(2015). Adipose tissue macrophages: the inflammatory link between obesity and cancer? Invited review. (external link)
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Bert-Inge Rosengren; Solfrid Johanne Sagstad; Tine Veronica Karlsen
et al. (2013). Isolation of interstitial fluid and demonstration of local proinflammatory cytokine production and increased absorptive gradient in chronic peritoneal dialysis. (external link)
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Joseph M. Rutkowski; Carl Erik Markhus; Christina Gyenge
et al. (2010). Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema. (external link)
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Tine Veronica Karlsen; Elham Nikpey; Jianhua Han
et al. (2018). High-Salt Diet Causes Expansion of the Lymphatic Network
and Increased Lymph Flow in Skin and Muscle of Rats. (external link)
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Olav Tenstad; Karin Johanne Heyeraas; Helge Wiig
et al. (2001). Drainage of plasma proteins from renal medullary interstitium in rats. (external link)
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Carl Erik Markhus; Helge Wiig
(2004). Isolation of interstitial fluid from skeletal muscle and subcutis in mice using a wick method. (external link)
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Anca Virtej; Olav Tenstad; Helge Wiig
et al. (2020). Interstitial fluid drainage from rat apical area takes place via vessels in the mandibular canal.. (external link)
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Frank Helle; Tine Veronica Karlsen; Olav Tenstad
et al. (2013). High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels. (external link)
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Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang
et al. (2019). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
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Ellen Berggreen; Helge Wiig
(2013). Lymphangiogenesis and lymphatic function in periodontal disease. (external link)
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Matthias Hofmann; Emmet Martin McCormack; Maja Mujic
et al. (2009). Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model. (external link)
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Helge Wiig; Odd Kolmannskog; Olav Tenstad
et al. (2003). Effect of charge on interstitial distribution of albumin in rat dermis in vitro. (external link)
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David Wright; Helge Wiig; Peter Winlove
et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
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Eli Sihn Samdal Steinskog; Kenneth Finne; Marianne Enger
et al. (2023). Isolation of lymph shows dysregulation of STAT3 and CREB pathways in the spleen and liver during leukemia development in a rat model. (external link)
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Amanda W. Lund; Marek Wagner; Manuel Fankhauser
et al. (2016). Lymphatic vessels regulate immune microenvironments in human and murine melanoma. (external link)
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Hideharu Tanaka; Tjøstolv Lund; Helge Wiig
et al. (1999). High dose Vitamin C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
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Per Ole Iversen; Helge Wiig
(2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
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Anne-Maj Samuelsson; Theda Ulrike Patricia Bartolomaeus; Harithaa Anandakumar
et al. (2023). VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats. (external link)
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Helge Wiig; Christina Gyenge; Per Ole Iversen
et al. (2008). The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: Potential therapeutic consequences. (external link)
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Elvira Semaeva; Olav Tenstad; Jørn Skavland
et al. (2010). Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation. (external link)
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Hans Jørgen Guthe; Torbjørn Nedrebø; Jan Kristian Damås
et al. (2018). Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: An open, longitudinal, observational study. (external link)
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Helge Wiig; Olav Tenstad; Per Ole Iversen
et al. (2010). Interstitial fluid: the overlooked component of the tumor microenvironment?. (external link)
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Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø
et al. (2008). Peritumoral TNFalpha administration influences tumor stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
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Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm
et al. (2017). Fluid accumulation after closure of atrial septal defects: the role of colloid osmotic pressure. (external link)
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Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø
et al. (2008). Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
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Laonard M. Ebah; Helge Wiig; Idalia Dawidowska
et al. (2013). Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema. (external link)
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Daniela Negrini; Alberto Passi; Katia Bertin
et al. (2001). Isolation of pulmonary interstitial fluid in rabbits by a modified wick technique. (external link)
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Majumi Kajimura; Helge Wiig; Rolf Kåre Reed
et al. (2001). Interstitial fluid pressure surrounding rat mesenteric venules during changes in fluid filtration. (external link)
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Bert Inge Rosengren; Bengt Rippe; Olav Tenstad
et al. (2004). Acute peritoneal dialysis in rats results in a marked reduction of interstitial colloid osmotic pressure. (external link)
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Fitz-Roy E. Curry; Cecilie Brekke; Tine Veronica Karlsen
et al. (2010). Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume. (external link)
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Per Ole Iversen; Elvira Semaeva; Dag R. Sørensen
et al. (2009). Dendritic cells loaded with tumor antigens and a dual immunostimulatory and anti-IL-10 specific siRNA can prime T lymphocytes against leukemic cells. (external link)
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Rawad H Mounzer; Øyvind Sverre Svendsen; Peter Baluk
et al. (2010). Lymphotoxin-alpha contributes to lymphangiogenesis. (external link)
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Hege Kristin Brekke; Eystein Oveland; Odd Kolmannskog
et al. (2010). Isolation of interstitial fluid in skin during volume expansion: evaluation of a method in pigs. (external link)
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Tine Veronica Karlsen; Emmet Martin McCormack; Maja Mujic
et al. (2012). Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kaja Christine Graue Berg
et al. (2011). A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue. (external link)
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Helge Wiig; Knut Aukland; Olav Tenstad
(2003). Isolation of interstitial fluid from rat mammary tumors by a centrifugation method. (external link)
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Alexei V. Salnikov; Nils-Erik Heldin; Linda Elin Birkhaug Stuhr
et al. (2006). Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. (external link)
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Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm
et al. (2019). Fluid accumulation in the staged Fontan procedure: the impact of colloid osmotic pressures. (external link)
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Lilian Ephrem Mkonyi; Athanasia Bletsa; Inge Fristad
et al. (2010). Importance of lymph vessels in transcapillary fluid balance in gingiva studied in a transgenic mouse model. (external link)
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Tommy A. Rehn; Bengt Åge Sørby Borge; Per K. Lunde
et al. (2009). Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats. (external link)
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Anca Virtej; Larissa Alexandrina von Marti; Marek Wagner
et al. (2024). Contribution of initial lymphatics to oral wound healing after tooth extraction. (external link)
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Knut Aukland; Rolf Kåre Reed; Helge Wiig
(1997). The problem of gaining access to interstitial fluid. An attempt to rationalize a wicked discussion on wicks. (external link)
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Hans Jørgen Timm Guthe; Torbjørn Nedrebø; Olav Tenstad
et al. (2012). Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique. (external link)
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Jaehwa Choi; Kimberly Credit; Karla Henderson
et al. (2006). Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration. (external link)
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Marek Wagner; Rolf Bjerkvig; Helge Wiig
et al. (2012). Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis. (external link)
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Marko Uutela; Maria Wirzenius; Karri Paavonen
et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
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Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig
(2019). Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation. (external link)
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Bengt Åge Sørby Borge; Karl-Henning Kalland; Sue Olsen
et al. (2009). Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia. (external link)
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Marek Wagner; Rolf Bjerkvig; Helge Wiig
et al. (2013). Loss of adipocyte specification and necrosis augment tumor-associated inflammation. (external link)
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Alf H. Øien; Olav Tenstad; Helge Wiig
(2024). Models of Hydration Dependent Lymphatic Opening, Interstitial Fluid Flows and Ambipolar Diffusion. (external link)
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Alf Hartvig Øien; Helge Wiig
(2018). Modeling In Vivo Interstitial Hydration-Pressure Relationships in Skin and Skeletal Muscle. (external link)
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Hans Jørgen Timm Guthe; Marianne Muller Indrebø; Torbjørn Nedrebø
et al. (2015). Interstitial fluid colloid osmotic pressure in healthy children. (external link)
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Linda Mullins; Jessica Ivy; Mairi Ward
et al. (2021). Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat. (external link)
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Helge Wiig; Kristofer Rubin; Rolf Kåre Reed
(2003). New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. (external link)
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Carl Erik Nordvik Markhus; Tine Veronica Karlsen; Marek Wagner
et al. (2013). Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. (external link)
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R Kvåle; RK Reed; Helge Wiig
et al. (1996). Iontoforese - gammelt prinsipp - nye bruksområder. (external link)
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Athanasia Bletsa; Ellen Berggreen; Inge Fristad
et al. (2006). Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation. (external link)
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Miro Julian Eigenmann; Tine Veronica Karlsen; Ben-Fillippo Krippendorff
et al. (2017). Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches. (external link)
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Rolf Kåre Reed; Kristofer Rubin; Helge Wiig
et al. (1992). Blockade of _b%b-Integrins in skin causes edema through lowering of interstitial fluid pressure. (external link)
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Tine Veronica Karlsen; Kari Alitalo; Marika J. Karkkainen
et al. (2006). Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema. (external link)
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Ellen Berggreen; Helge Wiig
(2006). Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion. (external link)
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Aeksanteri Aspelund; Salli Antila; Steven Proulx
et al. (2015). A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. (external link)
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Liliana Monica Bivol; Bjarne Magnus Iversen; Michael Hultström
et al. (2016). Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability. (external link)
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Elham Nikpey Esfahlan; Tine Veronica Karlsen; Natalia Rakova
et al. (2017). High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph. (external link)
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Solfrid Johanne Sagstad; Eystein Oveland; Tine Veronica Karlsen
et al. (2015). Extracellular matrix composition affects rat skin distribution volume of plasma proteins with different size and charge. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie
et al. (2015). Distribution volume of macromolecules in human ovarian and endometrial cancers - effects of extracellular matrix structure. (external link)
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Panagiota Papadakou; Tine Veronica Karlsen; Helge Wiig
et al. (2015). Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin. (external link)
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Knut Aukland; Helge Wiig; Olav Tenstad
et al. (1997). Interstitial exclusion of macromolecules studied by graded centrifugation. (external link)
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Helge Wiig; Olav Tenstad
(2001). Interstitial exclusion of positively and negatively charged IgG in rat skin and muscle. (external link)
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Helge Wiig; Tjøstolv Lund
(2001). Relationship between interstitial fluid volume and pressure (compliance) in hypothyroid rats. (external link)
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Knut Aukland; Olav Tenstad; Helge Wiig
(2001). Distribution spaces for hyaluronan and albumin in rat tail tendons. (external link)
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Harald Kryvi; Iselin Rusten; Per Gunnar Fjelldal
et al. (2017). The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development. (external link)
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Hanne Haslene-Hox; Amina Madani; Kaja Christine Graue Berg
et al. (2014). Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood. (external link)
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Lilian Ephrem Mkonyi; Athanasia Bletsa; Anne Isine Bolstad
et al. (2012). Gingival lymphatic drainage protects against porphyromonas gingivalis-induced bone loss in mice. (external link)
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Miro Julian Eigenmann; Tine Veronica Karlsen; Marek Wagner
et al. (2021). Pharmacokinetics and pharmacodynamics of t-cell bispecifics in the tumour interstitial fluid. (external link)
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Simone P Niclou; Claude Danzeisen; Hans Petter Eikesdal
et al. (2008). A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. (external link)
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Irene Matre Thowsen; Tine Veronica Karlsen; Elham Nikpey
et al. (2022). Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats. (external link)
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Marko Uutela; Maria Wirzenius; Karri Paavonen
et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
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Helge Wiig; Rolf Kåre Reed; Olav Tenstad
(2000). Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats. (external link)
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Daniela Negrini; Olav Tenstad; Helge Wiig
(2003). Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema. (external link)
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Ellen Berggreen; Helge Wiig; Karin Johanne Heyeraas
(2003). Blood flow and interstitial fluid pressure in the rat submandibular gland during changes in perfusion. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie
et al. (2013). Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue. (external link)
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Andras Maifeld; Johannes Wild; Tine Veronica Karlsen
et al. (2021). Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. (external link)
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Daisuke Nakano; Kento Kitada; Ningning Wan
et al. (2020). Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice. (external link)
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Helge Wiig
(2020). Commentary: Trends in cardiovascular medicine From deep in the heart - An emerging role of cardiac lymphatics. (external link)
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Alf Hartvig Øien; Sigrid Ravnsborg Justad; Olav Tenstad
et al. (2013). Effects of Hydration on Steric and Electric Charge-Induced Interstitial Volume Exclusion-a Model. (external link)
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Irene Matre Thowsen; Tore Reikvam; Trude Skogstrand
et al. (2022). Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension. (external link)
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Hideharu Tanaka; T Lund; Helge Wiig
et al. (1999). High dose vitamin-C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
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Matthias Hofmann; Maike Guschel; August Bernd
et al. (2006). Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model. (external link)
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Helge Wiig; Christina Gyenge; Olav Tenstad
(2005). The interstitial distribution of macromolecules in rat tumours is influenced by the negatively charged matrix components. (external link)
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Ellen G. Avery; Hendrik Bartolomaeus; Andras Maifeld
et al. (2021). The Gut Microbiome in Hypertension: Recent Advances and Future Perspectives. (external link)
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Elvira Semaeva; Olav Tenstad; Athanasia Bletsa
et al. (2008). Isolation of rat trachea interstitial fluid and demonstration of local cytokine production in lipopolysaccharide-induced systemic inflammation. (external link)
Non-fiction monograph
Conference abstract
Conference lecture
Conference poster
Academic literature review
Master’s thesis
Academic book chapter
Doctoral thesis (PhD)
Editorial/Leader article
Research report
See a complete overview of publications in Cristin.