Academic article

• Helge Wiig; D Keskin; Raghu Kalluri (2010). Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis og lymphatic function. (external link)
• Helge Wiig; L. Sibley; M. Decarlo et al. (1991). Sampling interstitial fluid from rat skeletal muscle by intermuscular wicks. (external link)
• Helge Wiig; Per Ole Iversen (2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
• Torbjørn Nedrebø; Rolf Kåre Reed; Roland Jonsson et al. (2004). Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats. (external link)
• Helge Wiig; Ellen Berggreen; Bengt Åge Sørby Borge et al. (2004). Demonstration of altered signaling responses in bone marrow extracellular fluid during increased hematopoiesis in rats using a centrifugation method. (external link)
• Helge Wiig; Agnes Schroeder; Wolfgang Neuhofer et al. (2013). Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. (external link)
• Panagiota Papadakou; Athanasia Bletsa; Mohammed Ahmed Alamin Yousif Yassin et al. (2017). Role of Hyperplasia of Gingival Lymphatics in Periodontal Inflammation. (external link)
• Øyvind Sverre Svendsen; Malgorzata Barczyk; Svetlana Popova et al. (2009). The alpha 11 beta 1 integrin has a mechanistic role in control of interstitial fluid pressure and edema formation in inflammation. (external link)
• David Michael Wright; Helge Wiig; C P Winlove et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
• Alf Hartvig Øien; Helge Wiig (2016). Electrostatic, elastic and hydration-dependent interactions in dermis influencing volume exclusion and macromolecular transport. (external link)
• W. B. Zhang; Knut Aukland; T. Lund et al. (2000). Distribution of interstitial fluid pressure and fluid volumes in hind-limb skin of rats: relation to meridians?. (external link)
• Daniela Negrini; Olav Tenstad; Helge Wiig (2003). Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique. (external link)
• Linda EB Stuhr; Alison Reith; Sigrid Lepsøe et al. (2003). Fluid pressure in human dermal fibroblast aggregates measured with micropipettes. (external link)
• Christina Gyenge; Olav Tenstad; Helge Wiig (2003). In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle. (external link)
• Tine Veronica Karlsen; Tore Reikvam; Anne Tofteberg et al. (2017). Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration. (external link)
• Eli Sihn Samdal Steinskog; Solfrid Johanne Sagstad; Marek Wagner et al. (2016). Impaired lymphatic function accelerates cancer growth. (external link)
• Christian Hinze; Janett Ruffert; Katharina Walentin et al. (2017). GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation. (external link)
• Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang et al. (2018). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
• Eystein Oveland; Tine Veronica Karlsen; Hanne Haslene-Hox et al. (2012). Proteomic Evaluation of Inflammatory Proteins in Rat Spleen Interstitial Fluid and Lymph during LPS-Induced Systemic Inflammation Reveals Increased Levels of ADAMST1. (external link)
• Daniela Negrini; Olav Tenstad; Alberto Passi et al. (2006). Differential degradation of matrix proteoglycans and edema development in rabbit lung. (external link)
• Helge Wiig; Olav Tenstad; Joel L. Bert (2005). Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro. (external link)
• Hanne Haslene-Hox; Olav Tenstad; Helge Wiig (2013). Interstitial fluid-a reflection of the tumor cell microenvironment and secretome. (external link)
• Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig (2015). Adipose tissue macrophages: the inflammatory link between obesity and cancer? Invited review. (external link)
• Bert-Inge Rosengren; Solfrid Johanne Sagstad; Tine Veronica Karlsen et al. (2013). Isolation of interstitial fluid and demonstration of local proinflammatory cytokine production and increased absorptive gradient in chronic peritoneal dialysis. (external link)
• Joseph M. Rutkowski; Carl Erik Markhus; Christina Gyenge et al. (2010). Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema. (external link)
• Tine Veronica Karlsen; Elham Nikpey; Jianhua Han et al. (2018). High-Salt Diet Causes Expansion of the Lymphatic Network and Increased Lymph Flow in Skin and Muscle of Rats. (external link)
• Olav Tenstad; Karin Johanne Heyeraas; Helge Wiig et al. (2001). Drainage of plasma proteins from renal medullary interstitium in rats. (external link)
• Carl Erik Markhus; Helge Wiig (2004). Isolation of interstitial fluid from skeletal muscle and subcutis in mice using a wick method. (external link)
• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2020). Interstitial fluid drainage from rat apical area takes place via vessels in the mandibular canal.. (external link)
• Frank Helle; Tine Veronica Karlsen; Olav Tenstad et al. (2013). High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels. (external link)
• Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang et al. (2019). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
• Ellen Berggreen; Helge Wiig (2013). Lymphangiogenesis and lymphatic function in periodontal disease. (external link)
• Matthias Hofmann; Emmet Martin McCormack; Maja Mujic et al. (2009). Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model. (external link)
• Helge Wiig; Odd Kolmannskog; Olav Tenstad et al. (2003). Effect of charge on interstitial distribution of albumin in rat dermis in vitro. (external link)
• David Wright; Helge Wiig; Peter Winlove et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
• Eli Sihn Samdal Steinskog; Kenneth Finne; Marianne Enger et al. (2023). Isolation of lymph shows dysregulation of STAT3 and CREB pathways in the spleen and liver during leukemia development in a rat model. (external link)
• Amanda W. Lund; Marek Wagner; Manuel Fankhauser et al. (2016). Lymphatic vessels regulate immune microenvironments in human and murine melanoma. (external link)
• Hideharu Tanaka; Tjøstolv Lund; Helge Wiig et al. (1999). High dose Vitamin C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
• Per Ole Iversen; Helge Wiig (2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
• Anne-Maj Samuelsson; Theda Ulrike Patricia Bartolomaeus; Harithaa Anandakumar et al. (2023). VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats. (external link)
• Helge Wiig; Christina Gyenge; Per Ole Iversen et al. (2008). The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: Potential therapeutic consequences. (external link)
• Elvira Semaeva; Olav Tenstad; Jørn Skavland et al. (2010). Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation. (external link)
• Hans Jørgen Guthe; Torbjørn Nedrebø; Jan Kristian Damås et al. (2018). Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: An open, longitudinal, observational study. (external link)
• Helge Wiig; Olav Tenstad; Per Ole Iversen et al. (2010). Interstitial fluid: the overlooked component of the tumor microenvironment?. (external link)
• Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø et al. (2008). Peritumoral TNFalpha administration influences tumor stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
• Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm et al. (2017). Fluid accumulation after closure of atrial septal defects: the role of colloid osmotic pressure. (external link)
• Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø et al. (2008). Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
• Laonard M. Ebah; Helge Wiig; Idalia Dawidowska et al. (2013). Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema. (external link)
• Daniela Negrini; Alberto Passi; Katia Bertin et al. (2001). Isolation of pulmonary interstitial fluid in rabbits by a modified wick technique. (external link)
• Majumi Kajimura; Helge Wiig; Rolf Kåre Reed et al. (2001). Interstitial fluid pressure surrounding rat mesenteric venules during changes in fluid filtration. (external link)
• Bert Inge Rosengren; Bengt Rippe; Olav Tenstad et al. (2004). Acute peritoneal dialysis in rats results in a marked reduction of interstitial colloid osmotic pressure. (external link)
• Fitz-Roy E. Curry; Cecilie Brekke; Tine Veronica Karlsen et al. (2010). Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume. (external link)
• Per Ole Iversen; Elvira Semaeva; Dag R. Sørensen et al. (2009). Dendritic cells loaded with tumor antigens and a dual immunostimulatory and anti-IL-10 specific siRNA can prime T lymphocytes against leukemic cells. (external link)
• Rawad H Mounzer; Øyvind Sverre Svendsen; Peter Baluk et al. (2010). Lymphotoxin-alpha contributes to lymphangiogenesis. (external link)
• Hege Kristin Brekke; Eystein Oveland; Odd Kolmannskog et al. (2010). Isolation of interstitial fluid in skin during volume expansion: evaluation of a method in pigs. (external link)
• Tine Veronica Karlsen; Emmet Martin McCormack; Maja Mujic et al. (2012). Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kaja Christine Graue Berg et al. (2011). A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue. (external link)
• Helge Wiig; Knut Aukland; Olav Tenstad (2003). Isolation of interstitial fluid from rat mammary tumors by a centrifugation method. (external link)
• Alexei V. Salnikov; Nils-Erik Heldin; Linda Elin Birkhaug Stuhr et al. (2006). Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. (external link)
• Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm et al. (2019). Fluid accumulation in the staged Fontan procedure: the impact of colloid osmotic pressures. (external link)
• Lilian Ephrem Mkonyi; Athanasia Bletsa; Inge Fristad et al. (2010). Importance of lymph vessels in transcapillary fluid balance in gingiva studied in a transgenic mouse model. (external link)
• Tommy A. Rehn; Bengt Åge Sørby Borge; Per K. Lunde et al. (2009). Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats. (external link)
• Anca Virtej; Larissa Alexandrina von Marti; Marek Wagner et al. (2024). Contribution of initial lymphatics to oral wound healing after tooth extraction. (external link)
• Knut Aukland; Rolf Kåre Reed; Helge Wiig (1997). The problem of gaining access to interstitial fluid. An attempt to rationalize a wicked discussion on wicks. (external link)
• Hans Jørgen Timm Guthe; Torbjørn Nedrebø; Olav Tenstad et al. (2012). Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique. (external link)
• Jaehwa Choi; Kimberly Credit; Karla Henderson et al. (2006). Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration. (external link)
• Marek Wagner; Rolf Bjerkvig; Helge Wiig et al. (2012). Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis. (external link)
• Marko Uutela; Maria Wirzenius; Karri Paavonen et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
• Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig (2019). Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation. (external link)
• Bengt Åge Sørby Borge; Karl-Henning Kalland; Sue Olsen et al. (2009). Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia. (external link)
• Marek Wagner; Rolf Bjerkvig; Helge Wiig et al. (2013). Loss of adipocyte specification and necrosis augment tumor-associated inflammation. (external link)
• Alf H. Øien; Olav Tenstad; Helge Wiig (2024). Models of Hydration Dependent Lymphatic Opening, Interstitial Fluid Flows and Ambipolar Diffusion. (external link)
• Alf Hartvig Øien; Helge Wiig (2018). Modeling In Vivo Interstitial Hydration-Pressure Relationships in Skin and Skeletal Muscle. (external link)
• Hans Jørgen Timm Guthe; Marianne Muller Indrebø; Torbjørn Nedrebø et al. (2015). Interstitial fluid colloid osmotic pressure in healthy children. (external link)
• Linda Mullins; Jessica Ivy; Mairi Ward et al. (2021). Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat. (external link)
• Helge Wiig; Kristofer Rubin; Rolf Kåre Reed (2003). New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. (external link)
• Carl Erik Nordvik Markhus; Tine Veronica Karlsen; Marek Wagner et al. (2013). Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. (external link)
• R Kvåle; RK Reed; Helge Wiig et al. (1996). Iontoforese - gammelt prinsipp - nye bruksområder. (external link)
• Athanasia Bletsa; Ellen Berggreen; Inge Fristad et al. (2006). Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation. (external link)
• Miro Julian Eigenmann; Tine Veronica Karlsen; Ben-Fillippo Krippendorff et al. (2017). Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches. (external link)
• Rolf Kåre Reed; Kristofer Rubin; Helge Wiig et al. (1992). Blockade of _b%b-Integrins in skin causes edema through lowering of interstitial fluid pressure. (external link)
• Tine Veronica Karlsen; Kari Alitalo; Marika J. Karkkainen et al. (2006). Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema. (external link)
• Ellen Berggreen; Helge Wiig (2006). Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion. (external link)
• Aeksanteri Aspelund; Salli Antila; Steven Proulx et al. (2015). A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. (external link)
• Liliana Monica Bivol; Bjarne Magnus Iversen; Michael Hultström et al. (2016). Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability. (external link)
• Elham Nikpey Esfahlan; Tine Veronica Karlsen; Natalia Rakova et al. (2017). High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph. (external link)
• Solfrid Johanne Sagstad; Eystein Oveland; Tine Veronica Karlsen et al. (2015). Extracellular matrix composition affects rat skin distribution volume of plasma proteins with different size and charge. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie et al. (2015). Distribution volume of macromolecules in human ovarian and endometrial cancers - effects of extracellular matrix structure. (external link)
• Panagiota Papadakou; Tine Veronica Karlsen; Helge Wiig et al. (2015). Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin. (external link)
• Knut Aukland; Helge Wiig; Olav Tenstad et al. (1997). Interstitial exclusion of macromolecules studied by graded centrifugation. (external link)
• Helge Wiig; Olav Tenstad (2001). Interstitial exclusion of positively and negatively charged IgG in rat skin and muscle. (external link)
• Helge Wiig; Tjøstolv Lund (2001). Relationship between interstitial fluid volume and pressure (compliance) in hypothyroid rats. (external link)
• Knut Aukland; Olav Tenstad; Helge Wiig (2001). Distribution spaces for hyaluronan and albumin in rat tail tendons. (external link)
• Harald Kryvi; Iselin Rusten; Per Gunnar Fjelldal et al. (2017). The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development. (external link)
• Hanne Haslene-Hox; Amina Madani; Kaja Christine Graue Berg et al. (2014). Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood. (external link)
• Lilian Ephrem Mkonyi; Athanasia Bletsa; Anne Isine Bolstad et al. (2012). Gingival lymphatic drainage protects against porphyromonas gingivalis-induced bone loss in mice. (external link)
• Miro Julian Eigenmann; Tine Veronica Karlsen; Marek Wagner et al. (2021). Pharmacokinetics and pharmacodynamics of t-cell bispecifics in the tumour interstitial fluid. (external link)
• Simone P Niclou; Claude Danzeisen; Hans Petter Eikesdal et al. (2008). A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. (external link)
• Irene Matre Thowsen; Tine Veronica Karlsen; Elham Nikpey et al. (2022). Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats. (external link)
• Marko Uutela; Maria Wirzenius; Karri Paavonen et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
• Helge Wiig; Rolf Kåre Reed; Olav Tenstad (2000). Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats. (external link)
• Daniela Negrini; Olav Tenstad; Helge Wiig (2003). Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema. (external link)
• Ellen Berggreen; Helge Wiig; Karin Johanne Heyeraas (2003). Blood flow and interstitial fluid pressure in the rat submandibular gland during changes in perfusion. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie et al. (2013). Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue. (external link)
• Andras Maifeld; Johannes Wild; Tine Veronica Karlsen et al. (2021). Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. (external link)
• Daisuke Nakano; Kento Kitada; Ningning Wan et al. (2020). Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice. (external link)
• Helge Wiig (2020). Commentary: Trends in cardiovascular medicine From deep in the heart - An emerging role of cardiac lymphatics. (external link)
• Alf Hartvig Øien; Sigrid Ravnsborg Justad; Olav Tenstad et al. (2013). Effects of Hydration on Steric and Electric Charge-Induced Interstitial Volume Exclusion-a Model. (external link)
• Irene Matre Thowsen; Tore Reikvam; Trude Skogstrand et al. (2022). Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension. (external link)
• Hideharu Tanaka; T Lund; Helge Wiig et al. (1999). High dose vitamin-C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
• Matthias Hofmann; Maike Guschel; August Bernd et al. (2006). Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2005). The interstitial distribution of macromolecules in rat tumours is influenced by the negatively charged matrix components. (external link)
• Ellen G. Avery; Hendrik Bartolomaeus; Andras Maifeld et al. (2021). The Gut Microbiome in Hypertension: Recent Advances and Future Perspectives. (external link)
• Elvira Semaeva; Olav Tenstad; Athanasia Bletsa et al. (2008). Isolation of rat trachea interstitial fluid and demonstration of local cytokine production in lipopolysaccharide-induced systemic inflammation. (external link)

Non-fiction monograph

• T. Hope; T. Lund; D. H. Elliott et al. (1994). Long Term Health Effects of Diving. (external link)
• A. Hope; T. Lund; D. H. Elliott et al. (1994). Long term health effects of diving. (external link)

Conference abstract

• Per Ole Iversen; Elvira Semaeva; DR Sorensen et al. (2009). A combined immunostimulatory and immunoinhibitory sirna with anti-leukemic properties in a rat model of acute myeloid leukemia. (external link)
• Leonard Ebah; Eystein Oveland; Ian Read et al. (2012). A LOOK BEYOND BLOOD IN THE UREMIC SYNDROME: COMPARATIVE ANALYSIS OF INTERSTITIAL FLUID AND PLASMA IN KIDNEY DISEASE. (external link)
• Rawad H Mounzer; Kris Bentley; Øyvind Sverre Svendsen et al. (2011). LTalpha CONTRIBUTES TO LYMPHATIC VESSEL DEVELOPMENT AND FUNCTION. (external link)
• PO Iversen; Helge Wiig (2005). Impaired hematopoiesis in acute myeloid leukemia is associated with elevated levels of tumor necrosis factor alpha and adiponectin in bone marrow, but not in plasma. (external link)
• Hege Kristin Brekke; Eystein Oveland; Olav Tenstad et al. (2010). ISOLATION AND IDENTIFICATION OF INFLAMMATORY SPECIFIC PROTEINS IN INTERSTITIAL FLUID IN SKIN DURING ACUTE OVERHYDRATION. (external link)
• Helge Wiig; Tine Veronica Karlsen; Olav Tenstad et al. (2013). Increased interstitial osmolality in skin of rats on a high salt diet. (external link)
• Elvira Semaeva; Eli-Anne Birgitte Gjerde; Olav Tenstad et al. (2006). Isolation of interstitial fluid and identification inflammatory mediators in rat trachea. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2005). Extracellular distribution of monoclonal antibodies and other macromolecules in tumors. (external link)
• Tine Veronica Karlsen; M Karkkainen; K Alitalo et al. (2005). Fluid volume regulation parameters in a mouse model of primary lymphedema. (external link)
• Leonard Ebah; Milin Nikam; Angela Summers et al. (2012). PRESSURE-VOLUME RELATIONSHIPS IN THE INTERSTITIAL COMPARTMENT OF PATIENTS WITH RENAL DYSFUNCTION AND OEDEMA; CLINICAL CORRELATES AND IMPLICATIONS FOR VOLUME ASSESSMENT. (external link)
• Matthias Hofmann; Maike Guschel; Gerd Signe Salvesen et al. (2006). Increased colloid osmotic pressure enhances the uptake of macromolecules in a xenograft tumor model. (external link)
• Olav Tenstad; Liliana Monica Bivol; Bjarne Magnus Iversen et al. (2013). Renal ischemia-reperfusion (I/R) injury induces a rapid activation of local inflammatory markers and causes increased peritubular permeability. (external link)
• Bert-Inge Rosengren; Christina Gyenge; Sue Olsen et al. (2006). Interstitial colloid osmotic pressures after chronic endothelial no production contributes to peritoneal dialysis. (external link)
• Matthias Hofmann; Emmet Martin McCormack; Helge Wiig et al. (2007). Increased uptake of macromolecules in a xenograft tumour model is facilitated via enhanced colloid osmotic pressure. (external link)
• Tommy Aune Rehn; Per Kristian Lunde; BA Borge et al. (2008). Contribution of skeletal muscle to cytokine production in heart failure. (external link)
• Matthias Hofmann; Emmet Martin McCormack; Helge Wiig et al. (2008). Application of serum albumin lowers tumour interstitial fluid pressure and increases the uptake of macromolecules in a xenograft tumour model. (external link)
• Jens Titze; Tine Karlson; Micheal Boschmann et al. (2011). Salt-sensitive hypertension is paralleled by sodium storage, interstitial hypertonicity, and increased interstitial fluid pressure in the skin. (external link)
• Matthias Hofmann; Emmet Martin McCormack; A Bernd et al. (2009). Intravenous application of serum albumin reduces the tumour interstitial fluid pressure and increases the absorption of therapeutics in a xenograft model. (external link)
• Matthias Hofmann; Emmet Martin McCormack; Helge Wiig et al. (2007). Enhanced colloid osmotic pressure facilitates the uptake of macromolecules in a xenograft tumour model. (external link)

Conference lecture

• Rolf Kåre Reed; Kristofer Rubin; Helge Wiig et al. (1993). Blockade of _b%b-integrins in skin causes edema through lowering of interstitial fluid pressure, (Pif). (external link)
• Helge Wiig; Olav Tenstad (2000). Exclusion of positively and negatively charged IgG in rat skin and muscle interstitium. (external link)

Conference poster

• Per Kristian Lunde; BÅS Borge; Annicke Stranda et al. (2006). Contribution of skeletal muscle to cytokine production in heart failure. (external link)
• Tommy Aune Rehn; BA Borge; Per Kristian Lunde et al. (2008). Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats. (external link)
• Tommy Aune Rehn; BA Borge; Per Kristian Lunde et al. (2008). Temporary alterations in skeletal muscle extracellular matrix during progression of congestive heart failure in rats. (external link)
• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2018). Lymphatic transport route from the dental pulp. (external link)
• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2019). Protein-rich fluid dynamics from the periapical mandibular area in rats. (external link)
• Daniela Negrini; Alberto Passi; Katia Bertin et al. (2000). Isolation of pulmonary interstitial fluid by a modified wick technique. (external link)
• Ellen Berggreen; Karin Johanne Heyeraas; Helge Wiig (2001). Blood flow and interstitial fluid pressure during changes in perfusion and after nervous stimulation in rat submandibular gland. (external link)

Academic literature review

• Svetlana Popova; Evy Lundgren-Äkerlund; Helge Wiig et al. (2007). Physiology and pathology of collagen receptors. (external link)
• Hidetaka Miyauchi; Sabrina Geisberger; Friedrich C. Luft et al. (2024). Sodium as an Important Regulator of Immunometabolism. (external link)
• Hanne Haslene-Hox; Olav Tenstad; Helge Wiig (2013). Interstitial fluid-A reflection of the tumor cell microenvironment and secretome. (external link)
• Helge Wiig; FC Luft; Jens M. Titze (2017). The interstitium conducts extrarenal storage of sodium and represents a third compartment essential for extracellular volume and blood pressure homeostasis. (external link)
• Helge Wiig; Melody A. Swartz (2012). Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2004). The contribution of sterical and electrostatical factors on distribution of macromolecules in the interstitial space. (external link)
• Ellen Berggreen; Helge Wiig (2014). Lymphatic function and responses in periodontal disease. (external link)
• Marek Wagner; Helge Wiig (2015). Tumor interstitial fluid formation, characterization, and clinical implications. (external link)
• Domenico Bagordo; Gian Paolo Rossi; Christian Delles et al. (2024). Tangram of Sodium and Fluid Balance. (external link)
• Ellen Berggreen; Helge Wiig; Anca Virtej (2020). Fluid transport from the dental pulp revisited. (external link)
• Bjørn Tore Gjertsen; Helge Wiig (2012). Investigation of therapy resistance mechanisms in myeloid leukemia by protein profiling of bone marrow extracellular fluid. (external link)
• Helge Wiig (2011). Pathophysiology of tissue fluid accumulation in inflammation. (external link)

Master’s thesis

• Anne Tofteberg; Helge Wiig; Tine Veronica Karlsen (2014). Interstitial Phenotype and Lymphatic Function in Mice Overexpressing Vascular Endothelial Growth Factor-C. (external link)
• Anne K. Jonassen; Helge Wiig; Neoma Tove Boardman (2006). Evaluation of the effect of direct activation of p70s6 kinase on cell survival after ischemic-reperfusion. (external link)

Academic book chapter

• Marek Wagner; Helge Wiig (2022). Lymphatics in Malignant Tumors. (external link)
• K. Aukland; Karin Johanne Heyeraas; Helge Wiig (1991). Arterial resistance in rat tail and kidney. (external link)
• Rolf Kåre Reed; Helge Wiig; T. Lund et al. (1992). Interstitial fluid pressure in control of interstitial fluid volume during normal conditions, injury and inflammation. (external link)
• Øyvind Sverre Svendsen; Rolf K. Reed; Helge Wiig (2011). The interstitium and lymphatics have an important role in edema generation during sepsis. (external link)
• Rolf Kåre Reed; Helge Wiig; T. Lund et al. (1992). Interstitial fluid pressure in control of interstitial fluid volume during normal conditions, injury and inflammation. (external link)

Doctoral thesis (PhD)

• Eli Sihn Samdal Steinskog; Helge Wiig; Olav Tenstad et al. (2017). Role of the microenvironment and lymphatics in cancer development. (external link)
• Helge Wiig (1986). Insterstitial fluid pressure and the relationship between interstitial fluid volume and pressure (compliance) in various organs and species. (external link)
• Solfrid Johanne Sagstad; Helge Wiig (2014). Role of the extracellular microenvironment and lymphatics in disease development and progression. (external link)
• Miro Julian Eigenmann; Helge Wiig (2017). Application of combined experimental and translational modeling approaches in early drug development. (external link)
• Elham Nikpey Esfahlan; Helge Wiig (2017). Role of the Extracellular Microenvironment and Lymphatics in Electrolyte and Blood Pressure Regulation. (external link)

Editorial/Leader article

• Helge Wiig (2018). Regulation of Fluid Volume From the Outside A Role of Glycosaminoglycans in the Skin Interstitium?. (external link)
• Helge Wiig (2008). Plasma protein charge: a majon determinant of fluid exchange. (external link)
• Thomas Robert; Anissa Moktefi; Helge Wiig et al. (2013). Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. (external link)
• Helge Wiig (2021). As for blood vessels, the answer regarding lymphatics is often NO. (external link)

Research report

• A Hope; T Lund; D Elliot et al. (1994). Long term health effect of diving. (external link)

See a complete overview of publications in Cristin.