Publications
Academic article
- Yin-Chen Hsieh; Mathias Bockwoldt; Ines Heiland (2025). ProTaxoVis—protein taxonomic visualisation of presence. (external link)
- Suraj Sharma; Roland Sauter; Madlen Hotze et al. (2025). GEMCAT - a new algorithm for gene expression-based prediction of metabolic alterations. (external link)
- Roland Sauter; Suraj Sharma; Ines Heiland (2024). Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems. (external link)
- Lena Elise Høyland; Magali R Van Linden; Marc Niere et al. (2024). Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+. (external link)
- Anna-Sophia Egger; Eva Rauch; Suraj Sharma et al. (2024). Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites. (external link)
- Suraj Sharma; Yin-Chen Hsieh; Jørn Dietze et al. (2022). Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria. (external link)
- Jørn Dietze; Alienke van Pijkeren; Anna-Sophia Egger et al. (2021). Natural isotope correction improves analysis of protein modification dynamics. (external link)
- Verena Panitz; Saša Končarević; Ahmed Sadik et al. (2021). Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma. (external link)
- Soumya R Mohapatra; Ahmed Sadik; Suraj Sharma et al. (2021). Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production. (external link)
- Mirja Tamara Prentzell; Ulrike Rehbein; Marti Cadena Sandoval et al. (2021). G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. (external link)
- Alienke Van Pijkeren; Jørn Dietze; Alejandro Sánchez Brotons et al. (2021). Combined metabolic and chemical (CoMetChem) labeling using stable isotopes - A strategy to reveal site-specific histone acetylation and deacetylation rates by LC-MS. (external link)
- Soumya R. Mohapatra; Ahmed Sadik; Lars-Oliver Tykocinski et al. (2019). Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma. (external link)
- Alexander Martin Heberle; Patricia Razquin Navas; Miriam Langelaar-Makkinje et al. (2019). The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner. (external link)
- Mathias Bockwoldt; Dorothee Houry; Marc Niere et al. (2019). Identification of evolutionary and kinetic drivers of NAD-dependent signaling. (external link)
- Mathias Bockwoldt; Ines Heiland; Karsten Fischer (2019). The evolution of the plastid phosphate translocator family. (external link)
- Arina Afanasyeva; Mathias Bockwoldt; Christopher Cooney et al. (2018). Human long intrinsically disordered protein regions are frequent targets of positive selection. (external link)
- Isabell Adam; Dyah L. Dewi; Joram Mooiweer et al. (2018). Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation. (external link)
- Sascha Schäuble; Anne-Kristin Stavrum; Mathias Bockwoldt et al. (2017). SBMLmod: a Python-based web application and web service for efficient data integration and model simulation. (external link)
- Dyah L Dewi; Soumya R Mohapatra; Saioa Blanco Cabañes et al. (2017). Suppression of indoleamine-2, 3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer. (external link)
- Christiane A. Opitz; Ines Heiland (2015). Dynamics of NAD-metabolism: everything but constant. (external link)
- Ines Heiland; K Thedieck (2015). Nutrigenomics: Toward a cross-disciplinary understanding of nutrient-driven networks in health and disease: What can we learn from the study of cross-talk in complex protein kinase and metabolic networks?. (external link)
- Ines Heiland (2014). Chemo Informatik: Was hat Tryptophan mit Krebs und Parkinson zu tun?. (external link)
- Walter Wencke; Bernd Ketelsen; Gaquerel Emmanuel et al. (2014). Improving the accuracy of expression data analysis in time course experiments using resampling. (external link)
- Kathrin Schmeisser; Johannes Mannsfeld; Doreen Kuhlow et al. (2013). Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide. (external link)
- Anne-Kristin Stavrum; Ines Heiland; Stefan Schuster et al. (2013). Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data. (external link)
- Sascha Schäuble; Anne-Kristin Stavrum; Pål Puntervoll et al. (2013). Effect of substrate competition in kinetic models of metabolic networks. (external link)
- Ines Heiland; Christoph Kaleta (2012). Stoffwechselanalyse: Neue Wege im Labyrinth entdecken. (external link)
Academic literature review
- Mathias Ziegler; Magnus Monnè; Andrey Nikiforov et al. (2021). Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25. (external link)
- Fabrizio Clarelli; Jingyi Liang; Antal Martinecz et al. (2019). Multi-scale modeling of drug binding kinetics to predict drug efficacy. (external link)
- Øyvind Strømland; Marc Niere; Andrey Nikiforov et al. (2019). Keeping the balance in NAD metabolism. (external link)
Conference lecture
- Ines Heiland (2022). Kinetic regulation of NAD homeostasis. (external link)
- Ines Heiland; Mathias Bockwoldt; Pål Puntervoll et al. (2016). Tissue specific models of Trp- and NAD-metabolism — insights into metabolic crosstalk.. (external link)
- Ines Heiland; Mathias Bockwoldt; Anne-Kristin Stavrum et al. (2016). Tissue specific models of Tryptohan-metabolism — insights into metabolic crosstalk. (external link)
- Mathias Bockwoldt; Ines Heiland (2016). Phylogenetic Analysis of NAD biosynthesis and consumption. (external link)
- Mathias Bockwoldt; Anne-Kristin Stavrum; Toni I. Gossmann et al. (2015). Dynamics of NAD-metabolism - everything but constant. (external link)
- Mathias Bockwoldt; Ines Heiland (2015). Phylogenetic Analysis of NAD biosynthesis and consumption. (external link)
- Wencke Walter; Emmanuel Gaquerel; Ian T. Baldwin et al. (2014). Improving the analysis of high throughput time course data using modelling based approaches. (external link)
- Ines Heiland (2013). Metabolic modelling: From networks to dynamics and back. (external link)
Conference poster
- Toni Ingolf Gossmann; Arina Afanasyeva; Mathias Bockwoldt et al. (2017). Human intrinsically long disordered protein regions are frequent targets of positive selection. (external link)
- Roland Sauter; Ines Heiland (2017). Arctic Marine Bioplastics. (external link)
- Roland Sauter; Ines Heiland (2016). Metabolic Modeling of Marine Biomass Conversion. (external link)
- Mathias Bockwoldt; Ines Heiland; Gossmann Toni et al. (2016). Phylogenetic and simulation-based analysis of NAD metabolism. (external link)
- Mathias Bockwoldt; Ines Heiland (2015). Use of resampling to improve accuracy of data analysis in time course experiments. (external link)
- Anne-Kristin Stavrum; Ines Heiland; Stefan Schuster et al. (2014). Predicting pathological metabolic changes using a kinetic model of tryptophan metabolism. (external link)
- Ines Heiland; Susanne Brandes; Anne-Kristin Stavrum et al. (2014). NAD-metabolism and the circadian clock -- Unraveling contradictions. (external link)
- Ines Heiland; Susanne Brandes; Anne-Kristin Stavrum et al. (2013). NAD-metabolism and the circadian clock. (external link)