- jan-inge.bjune@uib.no
- Visitor address
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Haukeland universitetssykehus, Laboratoriebygget
5009 Bergen - Postal address
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P.O. Box 7804NO-5020 BergenNorway
Short info
Research
Hormone Laboratory Research Group (https://www.uib.no/en/rg/hormonelaboratory)
Mohn Nutrition Research Laboratory (funded by the Mohn Foundation)
Outreach
Teaching
- NUTR115
- MEDMET900
- Supervision of masterstudents
Publications
Academic literature review
- Jan-Inge Bjune; Pouda Panahandeh Strømland; Regine Åsen Jersin et al. (2022). Metabolic and Epigenetic Regulation by Estrogen in Adipocytes. (external link)
- Tommy L.S. Visscher; Jeroen Lakerveld; Nanna Olsen et al. (2017). Perceived Health Status: Is Obesity Perceived as a Risk Factor and Disease?. (external link)
Conference lecture
- Jan-Inge Bjune (2017). Regulation of adipocyte browning by Irx5. (external link)
- Jan-Inge Bjune (2018). IRX5 regulerer APP og mitokondriell respirasjon i fettceller. (external link)
- Jan-Inge Bjune (2016). Transcriptional regulation of adipocyte browning by homeobox factors Irx3 and Irx5. (external link)
- Jan-Inge Bjune (2019). Irx3 er nødvendig for utvikling av fettceller. (external link)
- Jan-Inge Bjune; Samantha Laber; Laurence Dyer et al. (2021). Epigenetic control of adipogenesis by Irx3. (external link)
- Jan-Inge Bjune; Simon N Dankel; Shanima Shanu Mirza et al. (2022). Genetisk risiko for bukfedme. (external link)
- Jan-Inge Bjune (2018). Regulation of adipocyte metabolism by Irx3 and Irx5. (external link)
- Jan-Inge Bjune (2018). Regulation of adipocyte browning by Irx3 and Irx5. (external link)
Academic article
- Regine Åsen Jersin; Divya Sri Priyanka Tallapragada; Andre Madsen et al. (2021). Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance. (external link)
- Mark Colin Gissler; Nathaly Anto-Michel; Jan Pennig et al. (2021). Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. (external link)
- Mirushe Miftari; Jan-Inge Bjune; Chun Jun Rong et al. (2022). Choriolytic and non-choriolytic proteases during hatching of Atlantic Salmon embryos. (external link)
- Thea Sjøgren; Jan-Inge Bjune; Eystein Sverre Husebye et al. (2024). Regulatory T cells in autoimmune primary adrenal insufficiency. (external link)
- Jan-Inge Bjune; Samantha Laber; Laurence Dyer et al. (2025). IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells. (external link)
- Andre Greger Madsen; Jan Inge Bjune; Lise Bjørkhaug et al. (2016). The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. (external link)
- Jan-Inge Bjune; Laurence Dyer; Gro Vatne Røsland et al. (2019). The homeobox factor Irx3 maintains adipogenic identity. (external link)
- Andre Greger Madsen; Olivera Bozickovic; Jan Inge Bjune et al. (2015). Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). (external link)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. (external link)
- Simon N Dankel; Elise Grytten; Jan-Inge Bjune et al. (2020). COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. (external link)
Conference poster
- Andre Madsen; Olivera Bozickovic; Jan-Inge Bjune et al. (2016). Repression of liver SRC-2 by metformin inhibits glucose, lipid and cholesterol biosynthesis. (external link)
- Jan-Inge Bjune; Andre Madsen; Lise Bjørkhaug et al. (2016). PKA downregulates glucose-6phosphatase Expression through RORα and SRC2. (external link)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). Irx5 regulates body weight via amyloid precursor protein and mitochondrial respiration in adipocytes. (external link)
- Jan-Inge Bjune; Christine Haugen; Oddrun Anita Gudbrandsen et al. (2018). Irx5 regulates body weight via amyloid precursor protein (App) and mitochondrial respiration in adipocytes. (external link)
See a complete overview of publications in Cristin.
2025
Bjune JI, Laber S, Lawrence-Archer L, Nothnagel PMC, Yamada S, Zhao X, Strømland PP, Al-Sharabi N, Mustafa K, Njølstad PR, Claussnitzer M, Cox, RD, Chymkowitch P, Mellgren G, Dankel SN. IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells. Nat Commun 2025 Aug 6;16(1):7248. PMID: 40769964. IF 16.1
2024
Sjøgren T, Bjune JI, Husebye ES, Oftedal BE, Wolff ASB. Regulatory T cells in autoimmune primary adrenal insufficiency. Clin Exp Immunol. 2024 Jan 9;215(1):47-57. PMID: 37578839. IF 4.1
2022
Bjune JI*, Strømland PP*, Jersin RÅ*, Mellgren G, Dankel SN. Metabolic and Epigenetic Regulation by Estrogen in Adipocytes. Front Endocrinol (Lausanne). 2022 Feb 22;13:828780. doi: 10.3389/fendo.2022.828780. PMID: 35273571; PMCID: PMC8901598. IF 6.055
Miftari MH, Bjune JI, Rong CJ, Nilsen F, Walther BT. Choriolytic and non-choriolytic proteases during hatching of Atlantic Salmon embryos. Comp Biochem Physiol B Biochem Mol Biol. 2022 Oct-Dec;262:110776. IF 2.495.
2021
Gissler MC, Anto-Michel N, Pennig J, Scherrer P, Li X, Marchini T, Pfeiffer K, Härdtner C, Abogunloko T, Mwinyella T, Sol Mitre L, Spiga L, Koentges C, Smolka C, von Elverfeldt D, Hoppe N, Stachon P, Dufner B, Heidt T, Piepenburg S, Hilgendorf I, Bjune JI, Dankel SN, Mellgren G, Seifert G, Eisenhardt SU, Bugger H, von Zur Muhlen C, Bode C, Zirlik A, Wolf D, Willecke F. Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice. Arterioscler Thromb Vasc Biol. 2021 Oct;41(10):2563-2574. doi: 10.1161/ATVBAHA.121.316677. Epub 2021 Aug 5. PMID: 34348490. IF 10.514.
Jersin RÅ, Tallapragada DSP, Madsen A, Skartveit L, Fjære E, McCann A, Dyer L, Willems A, Bjune JI, Bjune MS, Våge V, Nielsen HJ, Thorsen HL, Nedrebø BG, Busch C, Steen VM, Blüher M, Jacobson P, Svensson PA, Fernø J, Rydén M, Arner P, Nygård O, Claussnitzer M, Ellingsen S, Madsen L, Sagen JV, Mellgren G, Dankel SN. Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance. Diabetes. 2021 Mar;70(3):680-695. doi: 10.2337/db20-0096. Epub 2021 Jan 6. PMID: 33408126. IF 9.305
2020
Dankel SN, Grytten E, Bjune JI, Nielsen HJ, Dietrich A, Blüher M, Sagen JV, Mellgren G. COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. Sci Rep. 2020 Nov 19;10(1):20164. doi: 10.1038/s41598-020-77406-2. PMID: 33214660; PMCID: PMC7678848. IF 4.997.
Bjune JI, Dyer L, Røsland GV, Tronstad KJ, Njølstad PR, Sagen JV, Dankel SN, Mellgren G. The homeobox factor Irx3 maintains adipogenic identity. Metabolism. 2020 Feb;103:154014. doi: 10.1016/j.metabol.2019.154014. Epub 2019 Nov 18. PMID: 31751577. IF 13.934.
2019
Bjune JI*, Haugen C*, Gudbrandsen O, Nordbø OP, Nielsen HJ, Våge V, NjølstadPR, Sagen JV, Dankel SN and Mellgren G. IRX5 regulates adipocyte amyloidprecursor protein and mitochondrial respiration in obesity. Int J Obes 2019;43:2151-62. IF 5.551.
2017
Visscher TL, Lakerveld J, Olsen N, Küpers L, Ramalho S, Keaver L, Brei C,Bjune JI, Ezquerro S, Yumuk V. Perceived Health Status: Is Obesity Perceived as a Risk Factor and Disease? Obes Facts. 2017;10(1):52-60. doi:10.1159/000457958. Epub 2017 Mar 10. PubMed PMID: 28278496. IF 4.807.
2016
Madsen A*, Bjune JI*, Bjørkhaug L, Mellgren G, Sagen JV. The cAMP-dependentprotein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity. Mol Cell Endocrinol. 2016 Jan5;419:92-101. doi: 10.1016/j.mce.2015.10.003. Epub 2015 Oct 9. PubMed PMID:26455881. IF 4.369.
2015
Madsen A, Bozickovic O, Bjune JI, Mellgren G, Sagen JV. Metformin inhibitshepatocellular glucose, lipid and cholesterol biosynthetic pathways bytranscriptionally suppressing steroid receptor coactivator 2 (SRC-2). Sci Rep.2015 Nov 9;5:16430. doi: 10.1038/srep16430. PubMed PMID: 26548416; PubMed Central PMCID: PMC4637908. IF 4.997.
*contributed equally