Academic article

• August Hoel; Fredrik Hoel; Sissel Dyrstad et al. (2026). Charting the circulating proteome in ME/CFS using cross-system profiling to uncover mechanistic insights. (external link)
• Øystein Fluge; Ingrid Gurvin Rekeland; Kari Sørland et al. (2025). Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study. (external link)
• Dionysios C. Watson; Defne Bayik; Simon Humberto Storevik et al. (2023). GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. (external link)
• Tor-Christian Aase Johannessen; Md Mahdi Hasan-Olive; Huaiyang Zhu et al. (2018). Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. (external link)
• Linn I. Hodneland; Ina Katrine Nitschke Pettersen; Julie Nikolaisen et al. (2015). A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology. (external link)
• Per O. Iversen; Dag R. Sørensen; Karl Johan Tronstad et al. (2006). A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. (external link)
• Sissel Elisabeth Dyrstad; Maria Lie Lotsberg; Tuan Zea Tan et al. (2021). Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with EGFR TKI and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells. (external link)
• Fredrik Hoel; August Hoel; Ina Katrine Nitschke Pettersen et al. (2021). A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome. (external link)
• Ingrid Moen; Anne Margrete Øyan; Karl-Henning Kalland et al. (2009). Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. (external link)
• Ingrid Gurvin Rekeland; Alexander Fosså; Asgeir Lande et al. (2020). Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study. (external link)
• Alexander Fosså; Knut Bjøro Smeland; Øystein Fluge et al. (2020). Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue. (external link)
• Julie Nikolaisen; Linn I. Hodneland; Ina Katrine Nitschke Pettersen et al. (2014). Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties. (external link)
• Lena Elise Høyland; Magali R Van Linden; Marc Niere et al. (2024). Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+. (external link)
• Agnete Svendsen; Joost JC Verhoeff; Heike Immervoll et al. (2011). Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. (external link)
• Karl Johan Tronstad; Kjetil Berge; Endre Dyrøy et al. (2001). Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. (external link)
• Terje Sundstrøm; Lars Prestegarden; Francisco Azuaje et al. (2019). Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis. (external link)
• Claire M. Larrieu; Simon Humberto Storevik; Joris Guyon et al. (2022). Refining the Role of Pyruvate Dehydrogenase Kinases in Glioblastoma Development. (external link)
• Jonas Walter; Silvia Bolognin; Suresh K. Poovathingal et al. (2021). The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. (external link)
• Hege Wergedahl; Kjetil Berge; Pavol Bohov et al. (2008). Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats. (external link)
• Jan-Inge Bjune; Laurence Dyer; Gro Vatne Røsland et al. (2019). The homeobox factor Irx3 maintains adipogenic identity. (external link)
• Øystein Fluge; Olav Mella; Ove Bruland et al. (2016). Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome.. (external link)
• Jui-Chih Chang; Shey-Lin Wu; Fredrik Hoel et al. (2016). Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial function. (external link)
• August Hoel; Tarig Osman; Fredrik Hoel et al. (2021). Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model. (external link)
• Rolf Kristian Berge; Karl Johan Tronstad; Kjetil Berge et al. (2005). The metabolic syndrome and the hepatic fatty acid drainage hypothesis. (external link)
• Therese Bredholt; Elisabeth Anne Okumu Dimba; Hanne Hagland et al. (2009). Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. (external link)
• Bjarte Skoe Erikstein; Emmet Martin McCormack; Karl Johan Tronstad et al. (2010). Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. (external link)
• Tia Tidwell; Gro Vatne Røsland; Karl Johan Tronstad et al. (2024). Comparing in vitro cytotoxic drug sensitivity in colon and pancreatic cancer using 2D and 3D cell models: Contrasting viability and growth inhibition in clinically relevant dose and repeated drug cycles. (external link)
• Ingrid Moen; Karl Johan Tronstad; Odd Kolmannskog et al. (2009). Hyperoxia increases the uptake of 5-FU in mammary tumors independently of cganges in interstitial pressure and tumor stroma. (external link)
• Jui-Chih Chang; Fredrik Hoel; Ko-Hung Liu et al. (2017). Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation. (external link)
• Hanne Hagland; Linn I. Hodneland; Lena Burri et al. (2013). Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA). (external link)
• Ingrid Gurvin Rekeland; Kari Sørland; Lisbeth Lykke Neteland et al. (2024). Six-year follow-up of participants in two clinical trials of rituximab or cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. (external link)
• Bjarte Skoe Erikstein; Hanne Hagland; Julie Nikolaisen et al. (2010). Cellular stress induced by resazurin leads to autophagy and cell death via production of reactive oxygen species and mitochondrial impairment. (external link)
• Rolf Kristian Berge; Lise Madsen; Hege Vaagenes et al. (1999). In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacyllycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation. (external link)
• Øystein Bruserud; Karl Johan Tronstad; Rolf Kristian Berge (2005). In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum. (external link)
• Johan Fernø; Maria Therese Barøy Ræder; Audun Osland Vik-Mo et al. (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. (external link)
• Tia R. Tidwell; Gro Vatne Røsland; Karl Johan Tronstad et al. (2022). Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines. (external link)
• Carine Lindquist; Bodil Bjørndal; Christine Renate Rossmann et al. (2017). Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats. (external link)
• Magali R Van Linden; Christian Dölle; Ina Katrine Nitschke Pettersen et al. (2015). Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. (external link)
• Ina Katrine Nitschke Pettersen; Deusdedit Tusubira; Hanan Ashrafi et al. (2019). Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation. (external link)
• Sissel Elisabeth Dyrstad; Deusdedit Tusubira; Stian Knappskog et al. (2018). Introducing nano-scale quantitative polymerase chain reaction. (external link)
• Abdelnour Alhourani; Tia Tidwell; Ansooya Avinash Bokil et al. (2021). Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells. (external link)
• Gro Vatne Røsland; Sissel Elisabeth Dyrstad; Deusdedit Tusubira et al. (2019). Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.. (external link)
• Jonas Walter; Silvia Bolognin; Paul M.A. Antony et al. (2019). Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality. (external link)
• Sissel Dyrstad; Kimberley Joanne Hatfield; Endre Stigen et al. (2025). Mapping of Functional Metabolic Phenotypes in Acute Myeloid Leukemia. (external link)
• Krishna Mukharji Talasila; Gro Vatne Røsland; Hanne Røland Hagland et al. (2017). The angiogenic switch leads to a metabolic shift in human glioblastoma. (external link)
• Ingrid Gurvin Rekeland; Kari Sørland; Ove Bruland et al. (2022). Activity monitoring and patient-reported outcome measures in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients. (external link)
• Øystein Bruserud; Karl Johan Tronstad; Emmet Martin McCormack et al. (2006). Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?. (external link)

Conference lecture

• Karl Johan Tronstad (2018). Cellular Energetics in ME/CFS. (external link)
• Karl Johan Tronstad (2017). Defective energy metabolism in ME/CFS (Prosjektpresentasjon, NFR BehovME, 2017-2020). (external link)
• Karl Johan Tronstad; Kjetil Berge; Odd Terje Brustugun et al. (1998). Metabolic effects of 3-thia fatty acid in cancer cells. (external link)
• Julie Nikolaisen; Linn I. Hodneland Nilsson; Hanne Røland Hagland et al. (2013). Mitochondrial function, biogenesis and morphology in cellular stress. (external link)
• Julie Nikolaisen; Linn I. Nilsson Hodneland; Hanne Røland Hagland et al. (2012). Mitochondrial morphology and biogenesis in cellular stress. (external link)

Lecture

• Karl Johan Tronstad (2018). Me-forskning i Bergen. (external link)
• Karl Johan Tronstad (2018). ME/CFS - Energisvikt i kroppens celler. (external link)
• Karl Johan Tronstad (2018). Cellular Energetics in ME/CFS (public). (external link)

Doctoral thesis (PhD)

• Ina Katrine Nitschke Pettersen; Karl Johan Tronstad (2017). A study of cellular metabolic flexibility under energy stress. (external link)
• Deusdedit Tusubira; Karl Johan Tronstad (2019). A study on features and markers of cellular metabolic rewiring. (external link)

Letter to the editor

• Karl Johan Tronstad; Øystein Fluge; Katarina Lien et al. (2017). Mer om pyruvat dehydrogenase og kronisk utmattelsessyndrom.. (external link)
• Karl Johan Tronstad; Øystein Fluge; Olav Mella (2017). Chronic fatigue syndrome and pyruvate dehydrogenase function.. (external link)
• Karl Johan Tronstad; Øystein Fluge; Olav Mella (2018). Kronisk utmattelsessyndrom og pyruvat dehydrogenasefunksjon. (external link)

Conference abstract

• Bjarte Skoe Erikstein; Karl Johan Tronstad; Emmet Martin McCormack et al. (2007). Synergistic anti-leukemic effect of protein kinase a activator and PPAR7agonist is independent of Bcl-2 status. (external link)
• L I H Nilsson; Julie Nikolaisen; Hanne Hagland et al. (2012). A mitochondrial reporter system for studies on NRF-1/AMPK activity and regulation in viable cells. (external link)
• Martha Chekenya; Inger Anne Netland; Joost JC Verhoeff et al. (2010). NG2 PROMOTES RESISTANCE TO IONIZING RADIATION BY ELEVATED PEROXIREDOXIN-1 AND DNA DAMAGE RESPONSE IN GLIOBLASTOMA MULTIFORME. (external link)
• Hanne Hagland; Julie Nikolaisen; Linn I. Hodneland et al. (2008). Mitochondrial function in cancer cell line models. (external link)

Conference poster

• Tia Tidwell; Hanne Røland Hagland; Gro Vatne Røsland et al. (2018). Metabolic profiling of Colorectal cancer in 3D. (external link)
• Therese Halvorsen Røst; Oddrun Anita Gudbrandsen; Karl Johan Tronstad et al. (2004). PPAR-delta activation in relation to reduction of adipose tissue. (external link)
• Ingrid Moen; Anne Margrete Øyan; Karl-Henning Kalland et al. (2009). Hyperoxic Treatment induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model. (external link)

Academic literature review

• Hanne Hagland; Julie Nikolaisen; Linn Iren Hodneland et al. (2007). Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling. (external link)
• Øystein Bruserud; Camilla I Stapnes; Karl Johan Tronstad et al. (2006). Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. (external link)
• Karl Johan Tronstad; Marco Nooteboom; Linn I. Hodneland et al. (2014). Regulation and quantification of cellular mitochondrial morphology and content.. (external link)
• Øystein Fluge; Karl Johan Tronstad; Olav Mella (2021). Pathomechanisms and possible interventions in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (external link)
• Brynjar Foss; Karl Johan Tronstad; Øystein Bruserud (2010). Connexin-based signaling in acute myelogenous leukemia (AML). (external link)

Master’s thesis

• Erna Irene Heggland; Trond Brattelid; Karl Johan Tronstad et al. (2015). The Role of Persistent Organic Pollutants in Induction of Endoplasmic Reticulum Stress in Hepatocytes in vitro and in vivo. (external link)
• Karl Johan Tronstad (1997). Proliferation of malignant rat glioma cells in reduced by the sulphur substituted fatty acid analogue tetradecylthioacetic acid; a stud on oxidative status (Cand. scient). (external link)
• Julie Nikolaisen; Karl Johan Tronstad (2007). Mitocondrial metabolism and tumor growth control. (external link)
• Anne K. Jonassen; Karl Johan Tronstad; Åshild Lien (2008). Growth Factors and Cardioprotection; - with special reference to insulin and IGF-II survival signalling at ischemic reperfusion. (external link)
• Lea Francine J Longueville; Karl Johan Tronstad; Knut Teigen et al. (2024). Characterization of mutations detected in a family of severe cases of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (external link)
• Aina Van Der Meeren; Karl Johan Tronstad; Ina Katrine Nitschke Pettersen (2020). Hunting metabolic changes in ME/CFS by investigating cellular responses to applied stress and patient serum factors. (external link)
• Anders Flataker Viken; Karl Johan Tronstad; Ina Katrine Nitschke Pettersen (2020). Exploring passive transfer of Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) metabolic disturbances on cultured mouse- and human muscle cells. (external link)
• Carine Lindquist; Bodil Bjørndal; Karl Johan Tronstad (2014). The effect of tetradedecylthioacetic acid on insulin production and mitochondrial function in INS-1E β-cells. (external link)
• Dina Manandar; Karl Johan Tronstad; James Lorens (2012). A study of mitochondrial function, ROS and signaling in Twist overexpressing cells. (external link)
• Ina Katrine Nitschke Pettersen; Karl Johan Tronstad; Laurence Bindoff (2012). Mitochondrial function and metabolic stress tolerance in fibroblasts from patients with mutations in POLG. (external link)
• Beate Hole Fosse; Anni Vedeler; Karl Johan Tronstad (2014). Effekt av hypoksia på Annexin A2 i mitokondrier fra HepG2- og PC12-celler. (external link)
• Ingunn Bergslien; Karl Johan Tronstad (2009). Mulige interaksjoner mellom tyrosin kinase reseptoren Axl, metabolisme og proliferasjon i brystkreftceller (MDA-MB-231). (external link)
• Gisle Størseth Solhaug; Karl Johan Tronstad (2009). Possible interactions between EGFR vIII mediated regulation of proliferation and metabolism in glioma cells. (external link)
• Silje Johannessen Hjellbrekke; Karl Johan Tronstad; Gro Vatne Røsland (2019). Alterations in cellular metabolism during development of cancer therapy resistance. (external link)
• Hanan Ashrafi; Ina Katrine Nitschke Pettersen; Karl Johan Tronstad (2019). The role of pyruvate dehydrogenase kinases (PDKs) in rewiring of cell metabolism under energy stress. (external link)
• Sissel Elisabeth Dyrstad; Karl Johan Tronstad; James Lorens (2013). Metabolic reprogramming in Slug and Twist overexpressing MCF10A cells. (external link)
• Bina Qassem Ahmed; Karl Johan Tronstad; Linn I. Hodneland (2011). AMPK som regulator av mitokondriell biogenese i en ny reporter-cellemodell. (external link)

Journal review

• Karl Johan Tronstad; Rolf Kristian Berge (2004). Book review: Lipid Biochemistry - An Introduction, 5th edn., edited by Michael I. Gurr, John L Harwood and Keith N. Frayn. Blackwell Science Ltd., Oxford (UK) 2002. (external link)

Journal corrigendum

• Abdelnour Alhourani; Tia Tidwell; Ansooya Avinash Bokil et al. (2022). Author Correction: Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells (Scientific Reports, (2021), 11, 1, (10487), 10.1038/s41598-021-89861-6). (external link)
• Linn Iren Hodneland Nilsson; Ina Katrine Nitschke Pettersen; Julie Nikolaisen et al. (2016). Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology.. (external link)

Academic commentary

• Karl Johan Tronstad; Øystein Fluge; Olav Mella (2018). Kronisk utmattelsessyndrom og pyruvat dehydrogenasefunksjon.. (external link)

See a complete overview of publications in NVA.

For an updated publication list see Pubmed.

(The links below may not be completely updated)