Academic literature review

• Anna Åkesson; Carl Öberg; Linnea Malmgren et al. (2025). Identification of cystatin C as a new marker of glomerular filtration rate, and of shrunken pore syndrome–a new kidney disorder defining selective glomerular hypofiltration syndromes–calls for expansion of the international KDIGO guidelines. (external link)
• Hanne Haslene-Hox; Olav Tenstad; Helge Wiig (2013). Interstitial fluid-A reflection of the tumor cell microenvironment and secretome. (external link)
• Linnea Malmgren; Carl Öberg; Emil den Bakker et al. (2022). The complexity of kidney disease and diagnosing it – cystatin C, selective glomerular hypofiltration syndromes and proteome regulation. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2004). The contribution of sterical and electrostatical factors on distribution of macromolecules in the interstitial space. (external link)

Academic article

• Jon Andsnes Berg; Øyvind Repstad; Trond Trætteberg Serkland et al. (2025). Student perspectives on AI‐supported formative assessment in pharmacology. (external link)
• Olav Tenstad; H.E. Williamson; K. Aukland (1994). Repeatable measurement of local and zonal GFR in the rat kidney with aprotinin. (external link)
• Olav Tenstad; H.E. Williamson; G. Clausen et al. (1994). Glomerular filtration and tubular absorption of the basic polypeptide aprotinin. (external link)
• Sofie Fagervoll Heltne; Sigrid Hovdenakk; Monika Kvernenes et al. (2024). Study preferences and exam outcomes in medical education: insights from renal physiology. (external link)
• Rolf E. Christiansen; Olav Tenstad; Sabine Leh et al. (2004). Glomerular charge selectivity is impaired in hypertensive nephropathy. (external link)
• Rolf E. Christiansen; Anca Beatrice Roald; Camilla Gjerstad et al. (2001). Renal hemodynamics in young and old spontaneously hypertensive rats during intrarenal infusion of arginine vasopressin. (external link)
• Knut Aukland; Helge Wiig; Olav Tenstad et al. (1997). Interstitial exclusion of macromolecules studied by graded centrifugation. (external link)
• Tine Veronica Karlsen; Elham Nikpey; Jianhua Han et al. (2018). High-Salt Diet Causes Expansion of the Lymphatic Network and Increased Lymph Flow in Skin and Muscle of Rats. (external link)
• Hans Jørgen Timm Guthe; Torbjørn Nedrebø; Olav Tenstad et al. (2012). Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique. (external link)
• Kenneth Finne; Hans-Peter Marti; Sabine Maria Leh et al. (2016). Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. (external link)
• Vincent Friden; Eystein Oveland; Olav Tenstad et al. (2011). The glomerular endothelial cell coat is essential for glomerular filtration. (external link)
• Aida Muslimovic; Vincent Friden; Olav Tenstad et al. (2020). The Liver and Kidneys mediate clearance of cardiac troponin in the rat. (external link)
• Helge Wiig; Olav Tenstad (2001). Interstitial exclusion of positively and negatively charged IgG in rat skin and muscle. (external link)
• Rolf E.F. Christiansen; Anca Beatrice Roald; Camilla Gjerstad et al. (2001). Renal hemodynamics in young and old spontaneously hypertensive rats during intrarenal infusion of arginine vasopressin. (external link)
• Reidun Kristin Kopperud; Cecilie Brekke Rygh; Tine Veronica Karlsen et al. (2017). Increased microvascular permeability in mice lacking Epac1 (Rapgef3). (external link)
• Rolf EF Christiansen; Anca B Roald; Olav Tenstad et al. (2000). Renal Hemodynamics in Young Spontaneously Hypertensive Rats (SHR) during Development of Hypertension. (external link)
• Knut Aukland; Olav Tenstad; Helge Wiig (2001). Distribution spaces for hyaluronan and albumin in rat tail tendons. (external link)
• Olav Tenstad; Karin Johanne Heyeraas; Helge Wiig et al. (2001). Drainage of plasma proteins from renal medullary interstitium in rats. (external link)
• Kathrine Sivertsen Åsrud; Ronja Bjørnstad; Reidun Kristin Kopperud et al. (2020). Epac1 null mice have nephrogenic diabetes insipidus with deficient corticopapillary osmotic gradient and weaker collecting duct tight junctions. (external link)
• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2020). Interstitial fluid drainage from rat apical area takes place via vessels in the mandibular canal.. (external link)
• Frank Helle; Tine Veronica Karlsen; Olav Tenstad et al. (2013). High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels. (external link)
• Bert Inge Rosengren; Bengt Rippe; Olav Tenstad et al. (2004). Acute peritoneal dialysis in rats results in a marked reduction of interstitial colloid osmotic pressure. (external link)
• Helge Wiig; Agnes Schroeder; Wolfgang Neuhofer et al. (2013). Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. (external link)
• O Bakoush; J Tencer; O Torffvit et al. (2004). Increased glomerular albumin permeability in old spontaneously hypertensive rats. (external link)
• Hanne Haslene-Hox; Amina Madani; Kaja Christine Graue Berg et al. (2014). Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood. (external link)
• Olav Tenstad; H.E. Williamson; G. Clausen et al. (1994). Glomerular filtration and tubular absorption of the basic polypeptide aprotinin. (external link)
• Fitz-Roy E. Curry; Cecilie Brekke; Tine Veronica Karlsen et al. (2010). Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume. (external link)
• Miro Julian Eigenmann; Tine Veronica Karlsen; Marek Wagner et al. (2021). Pharmacokinetics and pharmacodynamics of t-cell bispecifics in the tumour interstitial fluid. (external link)
• Alf H. Øien; Olav Tenstad; Helge Wiig (2024). Models of Hydration Dependent Lymphatic Opening, Interstitial Fluid Flows and Ambipolar Diffusion. (external link)
• Claudia Szczepanski; Olav Tenstad; Anne Baumann et al. (2014). Identification of a novel lytic peptide for the treatment of solid tumours. (external link)
• Hege Kristin Brekke; Eystein Oveland; Odd Kolmannskog et al. (2010). Isolation of interstitial fluid in skin during volume expansion: evaluation of a method in pigs. (external link)
• Cecilie Brekke; Guro Løkka; Ritva Heljäsvaara et al. (2014). Image-based assessment of microvascular function and structure in collagen XV- and XVIII-deficient mice. (external link)
• Rolf E.F. Christiansen; Anca Beatrice Roald; Olav Tenstad et al. (2002). Renal hemodynamics during development of hypertension in young spontaneously hypertensive rats. (external link)
• Tine Veronica Karlsen; Emmet Martin McCormack; Maja Mujic et al. (2012). Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kaja Christine Graue Berg et al. (2011). A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue. (external link)
• Synnøve Nymark Aasen; Heidi Espedal; Christopher Florian Holte et al. (2019). Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood-brain barrier. (external link)
• Alina Khramova; Roberto Boi; Vincent Fridén et al. (2021). Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease. (external link)
• Linda Mullins; Jessica Ivy; Mairi Ward et al. (2021). Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat. (external link)
• Kenneth Finne; Heidrun Vethe; Trude Skogstrand et al. (2014). Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats. (external link)
• Irene Matre Thowsen; Tine Veronica Karlsen; Elham Nikpey et al. (2022). Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats. (external link)
• Helge Wiig; Rolf Kåre Reed; Olav Tenstad (2000). Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats. (external link)
• Daniela Negrini; Olav Tenstad; Helge Wiig (2003). Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema. (external link)
• Daniela Negrini; Olav Tenstad; Helge Wiig (2003). Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique. (external link)
• Helge Wiig; Odd Kolmannskog; Olav Tenstad et al. (2003). Effect of charge on interstitial distribution of albumin in rat dermis in vitro. (external link)
• Helge Wiig; Knut Aukland; Olav Tenstad (2003). Isolation of interstitial fluid from rat mammary tumors by a centrifugation method. (external link)
• Christina Gyenge; Olav Tenstad; Helge Wiig (2003). In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle. (external link)
• Tine Veronica Karlsen; Tore Reikvam; Anne Tofteberg et al. (2017). Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration. (external link)
• Knut Ståle Erga; Elisabeth Peen; Olav Tenstad et al. (2000). Lactoferrin and anti-lactoferrin antibodies: Effects of ironloading of lactoferrin on albumin extravasation in different tissues in rats. (external link)
• Olav Tenstad; H.E. Williamson (1995). Effect of furosemide on local and zonal glomerular filtration rate in the rat kidney. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie et al. (2013). Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue. (external link)
• Carl Erik Nordvik Markhus; Tine Veronica Karlsen; Marek Wagner et al. (2013). Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. (external link)
• Rolf Espen Falk Christiansen; Anca Roald; Camilla Gjerstad et al. (2003). Renal hemodynamics in young and old spontaneously hypertensive rats during intrarenal infusion of arginine vasopressin. (external link)
• Eli Sihn Samdal Steinskog; Kenneth Finne; Marianne Enger et al. (2023). Isolation of lymph shows dysregulation of STAT3 and CREB pathways in the spleen and liver during leukemia development in a rat model. (external link)
• Aida Muslimovic; Vincent Friden; Karin Starnberg et al. (2020). Novel clearance of muscle proteins by muscle cells. (external link)
• Athanasia Bletsa; Ellen Berggreen; Inge Fristad et al. (2006). Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation. (external link)
• Alf Hartvig Øien; Sigrid Ravnsborg Justad; Olav Tenstad et al. (2013). Effects of Hydration on Steric and Electric Charge-Induced Interstitial Volume Exclusion-a Model. (external link)
• Irene Matre Thowsen; Tore Reikvam; Trude Skogstrand et al. (2022). Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension. (external link)
• Katrin Kleinmanns; Vibeke Samuelsen Fosse; Ben Davidson et al. (2020). CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model. (external link)
• Olav Tenstad; Eleni Christakou; Linn Hodneland Nilsson et al. (2024). In vivo turnover and biodistribution of soluble AXL: implications for biomarker development. (external link)
• Miro Julian Eigenmann; Tine Veronica Karlsen; Ben-Fillippo Krippendorff et al. (2017). Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches. (external link)
• Ulla Lund; Anna Rippe; Olav Tenstad et al. (2003). Glomerular filtration rate dependence of sieving of albumin and some neutral proteins in rat kidneys. (external link)
• Olav Tenstad; Anca B. Roald; A Grubb et al. (1996). Renal handling of radiolabelled human cystatin C in the rat. (external link)
• Christian Hinze; Janett Ruffert; Katharina Walentin et al. (2017). GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation. (external link)
• Eystein Oveland; Tine Veronica Karlsen; Hanne Haslene-Hox et al. (2012). Proteomic Evaluation of Inflammatory Proteins in Rat Spleen Interstitial Fluid and Lymph during LPS-Induced Systemic Inflammation Reveals Increased Levels of ADAMST1. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2005). The interstitial distribution of macromolecules in rat tumours is influenced by the negatively charged matrix components. (external link)
• Daniela Negrini; Olav Tenstad; Alberto Passi et al. (2006). Differential degradation of matrix proteoglycans and edema development in rabbit lung. (external link)
• Helge Wiig; Olav Tenstad; Joel L. Bert (2005). Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro. (external link)
• Dadash Baran; Olav Tenstad; Knut Aukland (2006). Localization of tubular uptake segment of filtered Cystatin C and Aprotinin in the rat kidney. (external link)
• Heidrun Vethe; Kenneth Finne; Trude Skogstrand et al. (2015). Distinct protein signature of hypertension-induced damage in the renal proteome of two-kidney-one-clip (2K1C) rat model. (external link)
• Anne-Maj Samuelsson; Theda Ulrike Patricia Bartolomaeus; Harithaa Anandakumar et al. (2023). VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats. (external link)
• Hanne Haslene-Hox; Olav Tenstad; Helge Wiig (2013). Interstitial fluid-a reflection of the tumor cell microenvironment and secretome. (external link)
• Helge Wiig; Christina Gyenge; Per Ole Iversen et al. (2008). The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: Potential therapeutic consequences. (external link)
• Liliana Monica Bivol; Bjarne Magnus Iversen; Michael Hultström et al. (2016). Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability. (external link)
• Rolf E.F. Christiansen; Odd Kolmannskog; Sabine Leh et al. (2008). Glomerular charge barrier and development of proteinuria in passive Heymann nephritis. (external link)
• Elham Nikpey Esfahlan; Tine Veronica Karlsen; Natalia Rakova et al. (2017). High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph. (external link)
• Dadash Baran; Olav Tenstad; Knut Aukland (2003). Aprotinin uptake in proximal tubules in the rat kidney II. Uptake site relative to glomerulus. (external link)
• Dadash Baran; Olav Tenstad; Knut Aukland (2003). Aprotinin uptake in the proximal tubules in the rat kidney I. Lenght of proximal tubular uptake segment. (external link)
• Elvira Semaeva; Olav Tenstad; Athanasia Bletsa et al. (2008). Isolation of rat trachea interstitial fluid and demonstration of local cytokine production in lipopolysaccharide-induced systemic inflammation. (external link)
• Elvira Semaeva; Olav Tenstad; Jørn Skavland et al. (2010). Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation. (external link)
• Anca Beatrice Roald; Knut Aukland; Olav Tenstad (2004). Tubular absortion of filtered cystatin-C in rat kidney. (external link)
• Marie Jeansson; Karin Björck; Olav Tenstad et al. (2009). Adriamycin Alters Glomerular Endothelium to Induce Proteinuria. (external link)
• Solfrid Johanne Sagstad; Eystein Oveland; Tine Veronica Karlsen et al. (2015). Extracellular matrix composition affects rat skin distribution volume of plasma proteins with different size and charge. (external link)
• Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie et al. (2015). Distribution volume of macromolecules in human ovarian and endometrial cancers - effects of extracellular matrix structure. (external link)
• Anca Beatrice Roald; Olav Tenstad; Knut Aukland (2004). The effect of AVP-V-1 receptor stimulation on local GFR in the rat kidney. (external link)
• Helge Wiig; Olav Tenstad; Per Ole Iversen et al. (2010). Interstitial fluid: the overlooked component of the tumor microenvironment?. (external link)

Conference abstract

• Kenneth Finne; Trude Skogstrand; Olav Tenstad et al. (2013). Proteomic analysis of outer and juxtamedullary cortex of non-clipped kidneys in 2K1C hypertensive rats. (external link)
• Olav Tenstad; Liliana Monica Bivol; Bjarne Magnus Iversen et al. (2013). Renal ischemia-reperfusion (I/R) injury induces a rapid activation of local inflammatory markers and causes increased peritubular permeability. (external link)
• Helge Wiig; Tine Veronica Karlsen; Olav Tenstad et al. (2013). Increased interstitial osmolality in skin of rats on a high salt diet. (external link)
• Tone Dolva Dahl; Trude Skogstrand; Frank Helle et al. (2013). Attenuated contractility in afferent arterioles during development of proteinuria in two-kidney, one-clip hypertensive rats. (external link)
• C Szczepanski; Rolf Bjerkvig; Olav Tenstad et al. (2011). Treatment of Solid Cancers Using a New Cationic Cytolytic Peptide. (external link)
• Jens Titze; Tine Karlson; Micheal Boschmann et al. (2011). Salt-sensitive hypertension is paralleled by sodium storage, interstitial hypertonicity, and increased interstitial fluid pressure in the skin. (external link)
• Bert-Inge Rosengren; Christina Gyenge; Sue Olsen et al. (2006). Interstitial colloid osmotic pressures after chronic endothelial no production contributes to peritoneal dialysis. (external link)
• Elvira Semaeva; Eli-Anne Birgitte Gjerde; Olav Tenstad et al. (2006). Isolation of interstitial fluid and identification inflammatory mediators in rat trachea. (external link)
• Helge Wiig; Christina Gyenge; Olav Tenstad (2005). Extracellular distribution of monoclonal antibodies and other macromolecules in tumors. (external link)
• Hege Kristin Brekke; Eystein Oveland; Olav Tenstad et al. (2010). ISOLATION AND IDENTIFICATION OF INFLAMMATORY SPECIFIC PROTEINS IN INTERSTITIAL FLUID IN SKIN DURING ACUTE OVERHYDRATION. (external link)

Lecture

• Olav Tenstad (1997). Glomerular filtration of lysozyme in the rat kidney - effect of varying net molecular charge and plasma protein concentration. (external link)

Doctoral thesis (PhD)

• Olav Tenstad (1995). Regional glomerular filtration (dr.med.). (external link)
• Eli Sihn Samdal Steinskog; Helge Wiig; Olav Tenstad et al. (2017). Role of the microenvironment and lymphatics in cancer development. (external link)
• Tone Dolva Dahl; Olav Tenstad (2015). Vascular function and the mechanism of proteinuria in hypertensive kidney disease. (external link)

Conference poster

• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2018). Lymphatic transport route from the dental pulp. (external link)
• Rolf E.F. Christiansen; Odd Kolmannskog; Sabine Leh et al. (2001). Proteinuria in passive Heymann Nephrithis, Importance of the glomerular charge barrier. (external link)
• Anca Virtej; Olav Tenstad; Helge Wiig et al. (2019). Protein-rich fluid dynamics from the periapical mandibular area in rats. (external link)

Academic book chapter

• K. Aukland; Olav Tenstad (1995). Renal interstitium, lymph and capillary uptake of tubular reabsorbate. (external link)

Master’s thesis

• Elisabeth Vaagen Samsøe; Bjarne Magnus Iversen; Olav Tenstad (2005). Cardiac output in development of genetic hypertension in rats. The use of thermodilution method in small animals; Validity and application. (external link)
• Solfrid Johanne Olsen; Olav Tenstad; Bjarne Magnus Iversen (2006). Effekt av ischemi på funksjon av glomerulær filtrasjon og proximal tubulus i rottenyre. (external link)
• Pål William Wallace; Olav Tenstad; Eystein Oveland (2011). An in vivo study of the glomerular sieving of endogenous proteins in rats. (external link)
• Olav Tenstad; Hanne Haslene-Hox; Kaja Christine Graue Berg (2011). Characterization of the protein contents of the tumour microenvironment of human gynaecological carcinomas. (external link)
• Ronja Bjørnstad; Stein Ove Doskeland; Olav Tenstad (2014). Characterization of the renal function in Epac1 (RapGef3) knockout mice. (external link)

Conference lecture

• Olav Tenstad (2007). Assessment of the glomerular charge barrier in vivo. (external link)
• Helge Wiig; Olav Tenstad (2000). Exclusion of positively and negatively charged IgG in rat skin and muscle interstitium. (external link)
• Olav Tenstad (1998). Glomerular filtration of lysozyme in the rat kidney - effect of varying net molecular charge and plasma protein concentration. (external link)
• Anca Roald; Olav Tenstad; Knut Aukland (1997). Glomerular filtration and tubular uptake of Cystatin C (Cy) in the rat kidney. (external link)
• F. Hestholm; Olav Tenstad; K. Aukland (1993). Extracellular space in the inner renal medulla. (external link)

See a complete overview of publications in NVA.