- rune.nielsen@uib.no
- Visitor address
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Haukeland universitetssykehus, Laboratoriebygget
5009 Bergen - Postal address
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P.O. Box 7804NO-5020 BergenNorway
Research groups
Research
2011: PhD in epidemiology and health economics of chronic obstructive pulmonary disease (COPD)
2012-2018: Postdoc on the MicroCOPD study working on data collection and bioinformatic analysis on the microbiota of the airways in COPD.
2018: Associate professor in respiratory medicine, supervision on projects on the microbiome and epidemiology in COPD.
Publications
2026
- Christina Svendsen; Rune Nielsen; Terje Hjalmar Larsen et al. (2026). The oral and lower airway microbiota and coronary heart disease in COPD patients and controls. (external link)
- Peter G.J. Burney; Emmanouil Bagkeris; James Potts et al. (2026). A cohort study of forced vital capacity, airway obstruction, and survival in the multinational Burden of Obstructive Lung Disease study. (external link)
- Guri Dahle Kringeland; Solveig Tangedal; Daniel Julian et al. (2026). Antimicrobial resistance genes and antibiotic use in chronic lung disease: a bronchoscopy study of the lower airways microbiome. (external link)
2025
- Abby H.S. Lam; Sheikhah A. Alhajri; James Potts et al. (2025). Optimal spirometry thresholds for the prediction of chronic airflow obstruction: a multinational longitudinal study. (external link)
- Ben Knox-Brown; James Potts; Frits M E Franssen et al. (2025). Concordance between FVC and FEV 6 for identifying chronic airflow obstruction and spirometric restriction in the Burden of Obstructive Lung Disease (BOLD) study. (external link)
- Christer Janson; James Potts; Andrei Malinovschi et al. (2025). Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study. (external link)
- Tomas Mikal Lind Eagan; Rune Nielsen; Ingvild Haaland et al. (2025). Inflammatory cells and remodeling in bronchial biopsies from COPD patients and controls. (external link)
- Hazim Abozid; Emiel F.M. Wouters; Hamid Hacene Cherkaski et al. (2025). Quality of life associated with chronic cough in the multinational Burden of Obstructive Lung Disease study: a cross-sectional study. (external link)
- Lucia Cestelli; Andre F. S. Amaral; Bryndis Benediktsdottir et al. (2025). The association between systemic inflammation, lung function and respiratory symptoms in the BOLD study in Northern Europe. (external link)
- Kristel Svalland Knudsen; Gunnar Reksten Husebø; Rune Nielsen et al. (2025). Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes. (external link)
- Anders Ørskov Rotevatn; Tomas Mikal Lind Eagan; Solveig Tangedal et al. (2025). Gut microbiota in chronic obstructive pulmonary disease varies by CT-verified emphysema status. (external link)
- Alexander Müller; Emiel F. M. Wouters; Peter Burney et al. (2025). Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis. (external link)
- Ben Knox-Brown; Fahad Algharbi; Octavia Mulhern et al. (2025). Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study. (external link)
- Peter G J Burney; James Potts; Ben Knox-Brown et al. (2025). Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study. (external link)
- Peter G.J. Burney; Tracey Nguyen; Dhiraj Agarwal et al. (2025). Fibular length and vital capacity in the multinational Burden of Obstructive Lung Disease follow-up study. (external link)
- Lucia Cestelli; Ane Johannessen; Amund Gulsvik et al. (2025). Risk Factors, Morbidity, and Mortality in Association With Preserved Ratio Impaired Spirometry and Restrictive Spirometric Pattern: Clinical Relevance of Preserved Ratio Impaired Spirometry and Restrictive Spirometric Pattern. (external link)
2011
- Rune Nielsen; Ane Johannessen; Ernst Omenaas et al. (2011). Excessive costs of COPD in ever-smokers. A longitudinal community study. (external link)
- Rune Nielsen (2011). Costs of chronic obstructive pulmonary disease in a general population. (external link)
- Cristina Rebordosa; Manolis Kogevinas; Sandra Guerra et al. (2011). ADRB2 Gly16Arg polymorphism, asthma control and lung function decline. (external link)
2019
- Christer Janson; Simone Accordini; Lucia Cazzoletti et al. (2019). Pharmacological treatment of asthma in a cohort of adults during a 20-year period: Results from the european community respiratory health survey I, II and III. (external link)
- Elisabet Nerpin; Mario Olivieri; Thorainn Gislason et al. (2019). Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III. (external link)
- Solveig Tangedal; Rune Nielsen; Marianne Aanerud et al. (2019). Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients. (external link)
- Einar Marius Hjellestad Martinsen; Tomas Mikal Eagan; Elise Orvedal Leiten et al. (2019). Motivation and response rates in bronchoscopy studies. (external link)
- Gunnar Husebø; Rune Nielsen; Jon Andrew Hardie et al. (2019). Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study. (external link)
- Christine Drengenes; Harald G Wiker; Tharmini Kalananthan et al. (2019). Laboratory contamination in airway microbiome studies. (external link)
- Ingvild Haaland; Solveig Tangedal; Rune Nielsen et al. (2019). Alterations in sputum inflammatory markers during exacerbations for COPD patients with different stable state levels. (external link)
- Rune Nielsen; Yaxin Xue; Inge Jonassen et al. (2019). Repeated bronchoscopy examination of the airway microbiome. (external link)
2022
- Alexander G. Mathioudakis; Fekri Abroug; Alvar Agusti et al. (2022). ERS statement: A core outcome set for clinical trials evaluating the management of COPD exacerbations. (external link)
- Einar Marius Hjellestad Martinsen; Tomas Mikal Lind Eagan; Harald Gotten Wiker et al. (2022). A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease. (external link)
- Kristel Svalland Knudsen; Sverre Lehmann; Rune Nielsen et al. (2022). The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease. (external link)
- Christina Due Svendsen; Karel Kier-Jan Kuiper; Kristoffer Ostridge et al. (2022). Factors associated with coronary heart disease in COPD patients and controls. (external link)
- Kristel Svalland Knudsen; Sverre Lehmann; Rune Nielsen et al. (2022). The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis. (external link)
- Lucia Cestelli; Ane Johannessen; Knut Stavem et al. (2022). Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century. (external link)
2020
- Ane Aamli Gagnat; Miriam Gjerdevik; Stein Atle Lie et al. (2020). Acute exacerbations of COPD and risk of lung cancer in COPD patients with and without a history of asthma. (external link)
- Gunnar Husebø; Esteban Gabazza; Corina D'Alessandro-Gabazza et al. (2020). Coagulation markers as predictors for clinical events in COPD. (external link)
- Elise Orvedal Leiten; Tomas Mikal Eagan; Einar Marius Hjellestad Martinsen et al. (2020). Complications and discomfort after research bronchoscopy in the MicroCOPD study. (external link)
- Ingvild Haaland; Marit Elisabeth Aardal; Frode Steingrimsen Berven et al. (2020). Changes in the induced sputum proteome during COPD exacerbations. (external link)
- Bahareh Jouleh; Ingvild Haaland; Fahimeh Khorsand et al. (2020). Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD. (external link)
- Marta Erdal; Ane Johannessen; Per S. Bakke et al. (2020). Incremental costs of COPD exacerbations in GOLD stage 2+ COPD in ever-smokers of a general population. (external link)
- Alexander G. Mathioudakis; Fekri Abroug; Alvar Agusti et al. (2020). Core outcome set for the management of acute exacerbations of chronic obstructive pulmonary disease: The cosaecopd ers task force study protocol. (external link)
- Elise Orvedal Leiten; Rune Nielsen; Harald Gotten Wiker et al. (2020). The airway microbiota and exacerbations of COPD. (external link)
- Amund Gulsvik; Per Bakke; Jan Brøgger et al. (2020). Respiratory symptoms and mortality in four general population cohorts over 45 years. (external link)
2021
- Knut Stavem; Ane Johannessen; Rune Nielsen et al. (2021). Respiratory symptoms and respiratory deaths: A multi-cohort study with 45 years observation time. (external link)
- Rune Nielsen; Yaxin Xue; Inge Jonassen et al. (2021). Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?. (external link)
- Einar Marius Hjellestad Martinsen; Tomas Mikal Lind Eagan; Elise Orvedal Leiten et al. (2021). The pulmonary mycobiome—A study of subjects with and without chronic obstructive pulmonary disease. (external link)
- Peter Burney; Jaymini Patel; Cosetta Minelli et al. (2021). Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study. (external link)
- Elisabet Nerpin; Diogenes Seraphim Ferreira; Joost Weyler et al. (2021). Bronchodilator response and lung function decline: Associations with exhaled nitric oxide with regard to sex and smoking status. (external link)
- André F.S. Amaral; Peter G.J. Burney; Jaymini Patel et al. (2021). Chronic airflow obstruction and ambient particulate air pollution. (external link)
- Christine Drengenes; Tomas Mikal Eagan; Ingvild Haaland et al. (2021). Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4. (external link)
2024
- Lucia Cestelli; Knut Stavem; Ane Johannessen et al. (2024). Outcome-based Definition of the Lower Limit of Normal in Spirometry: A Study of 26,000 Young Adult Men. (external link)
- Solveig Tangedal; Rune Nielsen; Marianne Aanerud et al. (2024). Lower airway microbiota in COPD and healthy controls. (external link)
2023
- Ben Knox-Brown; James Potts; Valentina Quintero Santofimio et al. (2023). Isolated small airways obstruction predicts future chronic airflow obstruction: a multinational longitudinal study. (external link)
- Ben Knox-Brown; Jaymini Patel; James Potts et al. (2023). Small airways obstruction and its risk factors in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study. (external link)
- Ema Rastoder; Pradeesh Sivapalan; Josefin Eklöf et al. (2023). Calcium Channel Blockers and the Risk of Exacerbation in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Study of 48,488 Outpatients. (external link)
- Lucia Cestelli; Amund Gulsvik; Ane Johannessen et al. (2023). Reduced lung function and cause-specific mortality: A population-based study of Norwegian men followed for 26 years. (external link)
- Jate Ratanachina; Andre F.S. Amaral; Sara De Matteis et al. (2023). Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study. (external link)
2016
- Marta Erdal; Ane Johannessen; Tomas Mikal Eagan et al. (2016). Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients. (external link)
- Einar Marius Hjellestad Martinsen; Elise Orvedal Leiten; Per S. Bakke et al. (2016). Participation in research bronchoscopy: a literature review. (external link)
- Elise Orvedal Leiten; Einar Marius Hjellestad Martinsen; Tomas Mikal Eagan et al. (2016). Complications and discomfort of bronchoscopy: a systematic review. (external link)
- Gunnar Husebø; Per S. Bakke; Rune Grønseth et al. (2016). Macrophage migration inhibitory factor, a role in COPD. (external link)
2014
- Gunnar Reksten Husebø; Per S. Bakke; Marianne Aanerud et al. (2014). Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. (external link)
- Rune Grønseth; William M. Vollmer; Jon Andrew Hardie et al. (2014). Predictors of dyspnoea prevalence: Results from the BOLD study. (external link)
- Marta Erdal; Ane Johannessen; Jan Erik Askildsen et al. (2014). Productivity losses in chronic obstructive pulmonary disease: a population-based survey.. (external link)
2013
- Bernd Lamprecht; Lowie E. Vanfleteren; Michael Studnicka et al. (2013). Sex-related differences in respiratory symptoms: results from the BOLD Study. (external link)
- Rune Nielsen; Hannu Kankaanranta; Leif Bjermer et al. (2013). Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries. (external link)
- Christer Janson; Guy Marks; Sonia Buist et al. (2013). The impact of COPD on health status: findings from the BOLD study. (external link)
2017
- Gunnar Husebø; Rune Grønseth; Lorena Lerner et al. (2017). Growth differentiation factor-15 is a predictor of important disease outcomes in patients with COPD. (external link)
- Rune Grønseth; Marta Erdal; Wan C. Tan et al. (2017). Unemployment in chronic airflow obstruction around the world: Results from the BOLD study. (external link)
- Solveig Tangedal; Marianne Aanerud; Rune Grønseth et al. (2017). Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. (external link)
2009
- Rune Nielsen; Ane Johannessen; Bryndis Benediktsdottir et al. (2009). Present and future costs of COPD in Iceland and Norway: results from the BOLD study. (external link)
- Rune Nielsen; Anne-Kristin M Johannessen; Per S. Bakke et al. (2009). How expensive is comorbidity in COPD?. (external link)
- Rune Nielsen; Ane Johannessen; Per S. Bakke et al. (2009). Aspects of healthcare utilisation in self-reported obstructive lung disease. (external link)