Respiratory Medicine to the medical students at the University of Bergen in MED4, MED5, MED6, MED11 and MED12. 

2011

• Ole Bernt Fasmer; Trond Riise; Tomas Mikal Eagan et al. (2011). Comorbidity of Asthma With ADHD. (external link)
• Bernt Bøgvald Aarli; PM Calverley; Tomas Mikal Eagan et al. (2011). Expiratory flow limitation (EFL) detected non-invasively as a phenotypic characteristic of COPD. (external link)
• Marie Waatevik; Jan Magnus Bjordal; Tomas Mikal Eagan (2011). 6 minutts gangtest hos KOLS-pasienter. (external link)
• Per S. Bakke; Eva Rönmark; Tomas Mikal Eagan et al. (2011). Recommendations for epidemiological studies on COPD. (external link)
• Kjetil Roth; Tomas Mikal Eagan; Alf Henrik Andreassen et al. (2011). A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions. (external link)
• Ole Bernt Fasmer; Anne Halmøy; Tomas Mikal Eagan et al. (2011). Adult attention deficit hyperactivity disorder is associated with asthma. (external link)
• Anne Edvardsen; Aina Akerø; Jon Andrew Hardie et al. (2011). High prevalence of respiratory symptoms during air travel in patients with COPD. (external link)

2016

• Louise Jeanette Pauline Persson; Tomas Mikal Eagan (2016). Vitamin D and antimicrobial peptides in COPD. Results from the Bergen COPD Cohort Study. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2016). Respiratory timing and dynamic hyperinflation during incremental exercise in patients with COPD. (external link)
• Tomas Mikal Eagan; Jon Andrew Hardie; Åsne Jul-Larsen et al. (2016). Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patients. (external link)
• Einar Marius Hjellestad Martinsen; Elise Orvedal Leiten; Per S. Bakke et al. (2016). Participation in research bronchoscopy: a literature review. (external link)
• Trygve Muller Jonassen; Tomas Mikal Eagan; Bjørn Bjorvatn et al. (2016). Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population. (external link)
• Elise Orvedal Leiten; Einar Marius Hjellestad Martinsen; Tomas Mikal Eagan et al. (2016). Complications and discomfort of bronchoscopy: a systematic review. (external link)
• Eirunn Waatevik Saure; Per S. Bakke; Tomas Mikal Eagan et al. (2016). Diffusion capacity and CT measures of emphysema and airway wall thickness – relation to arterial oxygen tension in COPD patients.. (external link)
• Kjetil Roth; Tomas Mikal Eagan; Jon Andrew Hardie (2016). Expert opinion of mediastinal lymph node positions from an intrabronchial view. (external link)
• Bernt Bøgvald Aarli; Peter MA Calverley; Xavier Soler et al. (2016). Longitudinal changes in Peak Oxygen Uptake in Chronic Obstructive Pulmonary Disease (COPD) Patients with Dynamic Hyperinflation and/or Tidal Expiratory Flow Limitation. (external link)
• Gunnar Husebø; Per S. Bakke; Rune Grønseth et al. (2016). Macrophage migration inhibitory factor, a role in COPD. (external link)
• Marie Johanne Wåtevik; Ane Johannessen; Francisco Gomez Real et al. (2016). Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD patients.. (external link)
• Marta Erdal; Ane Johannessen; Tomas Mikal Eagan et al. (2016). Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients. (external link)
• Michael Langballe Storebø; Tomas Mikal Eagan; Geir Egil Eide et al. (2016). Change in Pulmonary Diffusion Capacity in a General Population Sample over 9 Years. (external link)

2019

• Einar Marius Hjellestad Martinsen; Tomas Mikal Eagan; Elise Orvedal Leiten et al. (2019). Motivation and response rates in bronchoscopy studies. (external link)
• Anneloes L. van Rijn; Sander van Boheemen; Igor Sidorov et al. (2019). The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease. (external link)
• Anne M van der Does; Marieke Heijink; Oleg A. Mayboroda et al. (2019). Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls. (external link)
• Christine Drengenes; Harald G Wiker; Tharmini Kalananthan et al. (2019). Laboratory contamination in airway microbiome studies. (external link)
• Solveig Tangedal; Rune Nielsen; Marianne Aanerud et al. (2019). Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients. (external link)
• Ingvild Haaland; Solveig Tangedal; Rune Nielsen et al. (2019). Alterations in sputum inflammatory markers during exacerbations for COPD patients with different stable state levels. (external link)
• Gunnar Husebø; Rune Nielsen; Jon Andrew Hardie et al. (2019). Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study. (external link)

2014

• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2014). Physical activity and longitudinal change in 6-min walk distance in COPD patients. (external link)
• I. Mark Olfert; Moh H. Malek; Tomas Mikal Eagan et al. (2014). Inflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients 'on' or 'off' augmentation therapy. (external link)
• Eirunn Waatevik Saure; Tomas Mikal Eagan; Robert Leroy Jensen et al. (2014). Predictors for PaO2 and hypoxemic respiratory failure in COPD-A three-year follow-up. (external link)
• Ingvild Haaland; Marianne Aanerud; Solveig Tangedal et al. (2014). Interleukin-18 levels in induced sputum of stable and exacerbated COPD patients. (external link)
• Marta Erdal; Ane Johannessen; Jan Erik Askildsen et al. (2014). Productivity losses in chronic obstructive pulmonary disease: a population-based survey.. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2014). Longitudinal change in peak oxygen uptake in COPD patients. (external link)
• Tor Hatlestad Qvale; Anette Storstein; Kibret Yimer Mazengia et al. (2014). Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease. (external link)
• Rune Grønseth; Ingvild Haaland; Harald G Wiker et al. (2014). The Bergen COPD microbiome study (MicroCOPD): rationale, design, and initial experiences. (external link)
• Gunnar Reksten Husebø; Per S. Bakke; Marianne Aanerud et al. (2014). Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2014). Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients. (external link)
• Bernt Bøgvald Aarli; Peter MA Calverley; Tomas Mikal Eagan et al. (2014). Flow limitation during resting breathing is associated with reduced exercise capability in COPD.. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2014). Dynamic hyperinflation and respiratory timing during incremental exercise in patients with chronic obstructive pulmonary disease. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2014). Longitudinal change in peak oxygen uptake in COPD patients. (external link)
• Solveig Tangedal; Marianne Aanerud; Louise Jeanette Pauline Persson et al. (2014). Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients. (external link)
• Bernt Bøgvald Aarli; PM Calverley; Tomas Mikal Eagan et al. (2014). Mortality In COPD Patients With Increased Intrabreath Reactance. (external link)

2012

• Per S. Bakke; Eva Rönmark; Tomas Mikal Eagan et al. (2012). Recommendations for epidemiological studies on COPD. (external link)
• Tomas Mikal Eagan; Esteban C. Gabazza; Corina D'Alessandro-Gabazza et al. (2012). TNF-alpha is associated with loss of lean body mass only in already cachectic COPD patients. (external link)
• Bernt Bøgvald Aarli; PM Calverley; Tomas Mikal Eagan et al. (2012). Longitudinal Variability Of Expiratory Flow Limitation (EFL) In COPD Patients And Healthy Smokers Detected Non-invasively By Impulse Oscillometry. (external link)
• Bernt Bøgvald Aarli; PM Calverley; Tomas Mikal Eagan et al. (2012). Exacebation history in COPD patients with and without expiratory flow limitation (EFL).. (external link)
• Ane Johannessen; Per S. Bakke; Jon Andrew Hardie et al. (2012). Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2012). Predictors for longitudinal change in 6-Minute Walk Distance in COPD patients. (external link)
• Tor H. Qvale; Anette Storstein; Kibret Yimer Mazengia et al. (2012). Hu antibodies are present in smokers with chronic obstructive pulmonary disease without cancer or neurological disease. (external link)
• Marie Johanne Waatevik; Ane Johannessen; Jon Andrew Hardie et al. (2012). Different COPD disease characteristics are related to different outcomes in the 6-minute walk test. (external link)
• Louise Persson; Marianne Aanerud; Pieter Sicco Hiemstra et al. (2012). Chronic obstructive pulmonary disease is associated with low levels of vitamin D. (external link)
• Bjarte Gjerde; Per S. Bakke; Thor Ueland et al. (2012). The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway. (external link)
• Trygve Muller Jonassen; Tomas Mikal Eagan; Sverre Lehmann (2012). Daytime respiratory symptoms are associated with obstructive sleep apnoea syndrome. (external link)
• Eirunn Waatevik Saure; Tomas Mikal Eagan; Robert Leroy Jensen et al. (2012). Explained variance for blood gases in a population with COPD. (external link)

2024

• Marte Almenning Trollebø; Randi Julie Tangvik; Eli Skeie et al. (2024). Malnutrition as a prognostic factor for 2-year mortality in hospitalized patients in Norway: A matched cohort study. (external link)
• Ruben Dyrhovden; Tomas Mikal Lind Eagan; Øyvind Kommedal (2024). Pleural Infection: Contemporary Microbiology Completing the Picture. (external link)
• Solveig Tangedal; Rune Nielsen; Marianne Aanerud et al. (2024). Lower airway microbiota in COPD and healthy controls. (external link)
• Biplob Kumar Mohanty; Tomas Mikal Lind Eagan; Bernt Bøgvald Aarli et al. (2024). Trends in Non-Tuberculous Mycobacterial Lung Disease and Treatment Outcomes in a Low-Tuberculosis Prevalence Setting: A Retrospective Analysis. (external link)
• Øyvind Kommedal; Tomas Mikal Lind Eagan; Øystein Fløtten et al. (2024). Microbiological diagnosis of pleural infections: a comparative evaluation of a novel syndromic real-time PCR panel. (external link)

2017

• Gunnar Husebø; Rune Grønseth; Lorena Lerner et al. (2017). Growth differentiation factor-15 is a predictor of important disease outcomes in patients with COPD. (external link)
• Marit Elisabeth Aardal; Lene Løvendahl Svendsen; Sverre Lehmann et al. (2017). A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability. (external link)
• Marie Waatevik; Tomas Mikal Eagan; Jon Andrew Hardie et al. (2017). Repeated desaturation in 6 minute walk test increases risk for mortality in COPD patients. (external link)
• Solveig Tangedal; Marianne Aanerud; Rune Grønseth et al. (2017). Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. (external link)
• Linn Tharaldsen Aalstad; Jon Andrew Hardie; Einar Thorsen et al. (2017). Static hyperinflation and decline in functional capacity in COPD patients. (external link)
• Douglas J. Conrad; Barbara A. Bailey; Jon Andrew Hardie et al. (2017). Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients. (external link)
• Bernt Bøgvald Aarli; Peter M.A. Calverley; Robert L. Jensen et al. (2017). The association of tidal EFL with exercise performance, exacerbations, and death in COPD. (external link)
• Louise Jeanette Pauline Persson; Marianne Aanerud; Jon Andrew Hardie et al. (2017). Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease. (external link)
• Rune Grønseth; Christine Drengenes; Harald G Wiker et al. (2017). Protected sampling is preferable in bronchoscopic studies of the airway microbiome. (external link)

2010

• Tomas Mikal Lind Eagan; Jan Kristian Damås; Thor Ueland et al. (2010). Neutrophil Gelatinase-Associated Lipocalin A Biomarker in COPD. (external link)
• Marianne Voll-Aanerud; Tomas Mikal Lind Eagan; Estel Plana et al. (2010). Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey. (external link)
• Anne Edvardsen; Aina Akerø; Tomas Mikal Lind Eagan et al. (2010). Air travel habits in patients with COPD. (external link)
• Tomas Mikal Lind Eagan; Thor Ueland; Peter D. Wagner et al. (2010). Systemic inflammatory markers in chronic obstructive pulmonary disease – results from the Bergen COPD Cohort Study. (external link)
• Thomas Grydeland; Asger Dirksen; Harvey O. Coxson et al. (2010). Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. (external link)
• Bernt Bøgvald Aarli; Peter Calverley; Tomas Mikal Eagan et al. (2010). Reference values for resistance and reactance measures from Impuls Oscillometry in healthy elderly. (external link)
• Kjetil Roth; Tomas Mikal Eagan; Jon Andrew Hardie (2010). Significance of endobronchial lesion appearance in the diagnostic value of different endoscopic techniques Response. (external link)
• Ane Johannessen; Tomas Mikal Lind Eagan; Ernst Omenaas et al. (2010). Socioeconomic risk factors for lung function decline in a general population. (external link)
• Anne Edvardsen; Aina Akerø; Tomas Mikal Lind Eagan et al. (2010). In-flight respiratory symptoms and pre-flight characteristics in patients with COPD. (external link)
• Tomas Mikal Lind Eagan; Pål Aukrust; Per S. Bakke et al. (2010). Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. (external link)
• Tomas Mikal Lind Eagan; Pål Aukrust; Thor Ueland et al. (2010). Body composition and plasma levels of inflammatory biomarkers in COPD. (external link)

2013

• Ane Johannessen; Roy Miodini Nilsen; Michael Langballe Storebø et al. (2013). Comparison of 2011 and 2007 global initiative for chronic obstructive lung disease guidelines for predicting mortality and hospitalization. (external link)
• Bente Frisk; Birgitte Espehaug; Jon Andrew Hardie et al. (2013). Slope and curvature of the relationship between ventilation and tidal volume in COPD patients. (external link)
• Bernt Bøgvald Aarli; Tomas Mikal Eagan; Ivar Ellingsen et al. (2013). Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly. (external link)
• Kia Minna Hynninen; Ståle Pallesen; Jon Andrew Hardie et al. (2013). Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients. (external link)
• Marianne Aanerud; Harald Braut; Tore Wentzel-Larsen et al. (2013). Non-response in telephone surveys of COPD patients does not introduce bias. (external link)
• Bernt Bøgvald Aarli; PM Calverley; Tomas Mikal Eagan et al. (2013). Can intra-breath variations of reactance predict dyspnea?. (external link)

2020

• Bahareh Jouleh; Ingvild Haaland; Fahimeh Khorsand et al. (2020). Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD. (external link)
• Elise Orvedal Leiten; Rune Nielsen; Harald Gotten Wiker et al. (2020). The airway microbiota and exacerbations of COPD. (external link)
• Ingvild Haaland; Marit Elisabeth Aardal; Frode Steingrimsen Berven et al. (2020). Changes in the induced sputum proteome during COPD exacerbations. (external link)
• Marie Johanne Wåtevik; Bente Frisk; Francisco Gomez Real et al. (2020). One Year Change in 6-Minute Walk Test Outcomes is Associated with COPD Prognosis. (external link)
• Gunnar Husebø; Esteban Gabazza; Corina D'Alessandro-Gabazza et al. (2020). Coagulation markers as predictors for clinical events in COPD. (external link)
• Elise Orvedal Leiten; Tomas Mikal Eagan; Einar Marius Hjellestad Martinsen et al. (2020). Complications and discomfort after research bronchoscopy in the MicroCOPD study. (external link)
• Marta Erdal; Ane Johannessen; Per S. Bakke et al. (2020). Incremental costs of COPD exacerbations in GOLD stage 2+ COPD in ever-smokers of a general population. (external link)
• Michael Durheim; Anna-Maria Hoffmann-Vold; Tomas Mikal Eagan et al. (2020). ILD-specific health-related quality of life in systemic sclerosis-associated ILD compared with IPF. (external link)

2009

• Trude Duelien Skorge; Tomas Mikal Lind Eagan; Geir Egil Eide et al. (2009). Occupational exposure and incidence of respiratory disorders in a general population. (external link)
• Thomas Grydeland; Asger Dirksen; Harvey O. Coxson et al. (2009). Quantitative CT Measures of Emphysema and Airway Wall Thickness Are Related to Respiratory Symptoms. (external link)
• Tomas Mikal Lind Eagan; Pål Aukrust; Per S. Bakke et al. (2009). Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. (external link)
• Kjetil Roth; Jon Andrew Hardie; Alf Henrik Andreassen et al. (2009). Cost minimization analysis for combinations of sampling techniques in bronchoscopy of endobronchial lesions. (external link)
• Bernt Bøgvald Aarli; Robert L. Jensen; Tomas Mikal Eagan et al. (2009). Within-day repeatability and signal to noise ratio for IOS parameters and FEV1 in smokers with and without COPD. (external link)

2022

• Kristel Svalland Knudsen; Sverre Lehmann; Rune Nielsen et al. (2022). The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease. (external link)
• Trygve Müller Jonassen; Bjørn Bjorvatn; Ingvild W. Saxvig et al. (2022). Clinical information predicting severe obstructive sleep apnea: A cross-sectional study of patients waiting for sleep diagnostics. (external link)
• Kristel Svalland Knudsen; Sverre Lehmann; Rune Nielsen et al. (2022). The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis. (external link)
• Ellen C. Carbo; Igor A. Sidorov; Anneloes L. van Rijn-Klink et al. (2022). Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort. (external link)
• Einar Marius Hjellestad Martinsen; Tomas Mikal Lind Eagan; Harald Gotten Wiker et al. (2022). A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease. (external link)
• Marte Almenning Trollebø; Eli Skeie; Ingrid Revheim et al. (2022). Comparison of nutritional risk screening with NRS2002 and the GLIM diagnostic criteria for malnutrition in hospitalized patients. (external link)
• Christina Due Svendsen; Karel Kier-Jan Kuiper; Kristoffer Ostridge et al. (2022). Factors associated with coronary heart disease in COPD patients and controls. (external link)

2023

• Ruben Dyrhovden; Tomas Mikal Lind Eagan; Øystein Fløtten et al. (2023). Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections. (external link)
• Tonje Bårdsen; Ola Drange Røksund; Tomas Mikal Lind Eagan et al. (2023). Impaired Lung Function in Extremely Preterm-Born Adults in Their Fourth Decade of Life. (external link)

2018

• Bahareh Jouleh; Marta Erdal; Tomas Mikal Eagan et al. (2018). Guideline adherence in hospital recruited and population based COPD patients. (external link)
• Bernt Bøgvald Aarli; Jon Andrew Hardie; Tomas Mikal Eagan et al. (2018). Tidal Expiratory Flow Limitation. A new method for evaluating pulmonary function in elderly and patients with Chronic Obstructive Pulmonary Disease. (external link)
• Linn Tharaldsen Aalstad; Jon Andrew Hardie; Birgitte Espehaug et al. (2018). Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study. (external link)

2007

• Marianne Aanerud; Tomas Mikal Lind Eagan; Tore Wentzel-Larsen et al. (2007). Changes in Respiratory Symptoms and Health-Related Quality of Life. (external link)
• Trude Duelien Skorge; Tomas Mikal Lind Eagan; Geir Egil Eide et al. (2007). JEM-based occupational exposure assessment and incidence of respiratory disorders in a community sample. (external link)

2015

• Bente Frisk; Jon Andrew Hardie; Birgitte Espehaug et al. (2015). Peak oxygen uptake and breathing pattern in COPD patients - a four-year longitudinal study. (external link)
• Bernt Bøgvald Aarli; Peter M.A. Calverley; Robert L. Jensen et al. (2015). Variability of within-breath reactance in COPD patients and its association with dyspnoea. (external link)
• Louise Jeanette Pauline Persson; Marianne Aanerud; Pieter Sicco Hiemstra et al. (2015). Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD. (external link)
• Marianne Aanerud; Eirunn Waatevik Saure; Marta Benet et al. (2015). Serial measurements of arterial oxygen tension are associated with mortality in COPD. (external link)
• Bente Frisk; Jon Andrew Hardie; Birgitte Espehaug et al. (2015). Peak oxygen uptake and breathing pattern in COPD patients – a four year longitudinal study. (external link)

2021

• Marie Wåtevik; Bente Frisk; Francisco Gomez Real et al. (2021). CT-defined emphysema in COPD patients and risk for change in desaturation status in 6-min walk test. (external link)
• Rune Nielsen; Yaxin Xue; Inge Jonassen et al. (2021). Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?. (external link)
• Einar Marius Hjellestad Martinsen; Tomas Mikal Lind Eagan; Elise Orvedal Leiten et al. (2021). The pulmonary mycobiome—A study of subjects with and without chronic obstructive pulmonary disease. (external link)
• Christine Drengenes; Tomas Mikal Eagan; Ingvild Haaland et al. (2021). Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4. (external link)
• Daanyaal Wasim; Bjørn Arild Alme; Stina Jordal et al. (2021). Characteristics of 24-hour ambulatory blood pressure monitoring in a COVID-19 survivor. (external link)

2025

• Marte Almenning Trollebø; Randi Julie Tangvik; Eli Skeie et al. (2025). Metabolic profiles and malnutrition in hospitalized adults: A metabolomic cohort study. (external link)
• Kristel Svalland Knudsen; Gunnar Reksten Husebø; Rune Nielsen et al. (2025). Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes. (external link)
• Anders Ørskov Rotevatn; Tomas Mikal Lind Eagan; Solveig Tangedal et al. (2025). Gut microbiota in chronic obstructive pulmonary disease varies by CT-verified emphysema status. (external link)
• Tomas Mikal Lind Eagan; Rune Nielsen; Ingvild Haaland et al. (2025). Inflammatory cells and remodeling in bronchial biopsies from COPD patients and controls. (external link)

2026

• Trygve Müller Jonassen; Bjørn Bjorvatn; Sahrai Saeed et al. (2026). Impact of obstructive lung disease and sleep apnea symptoms on cardiovascular risk and all-cause mortality: insights from a community-dwelling cohort. (external link)

2008

• Kjetil Roth; Jon Andrew Hardie; Alf Henrik Andreassen et al. (2008). Predictors of diagnostic yield in bronchoscopy: a retrospective cohort study comparing different combinations of sampling techniques. (external link)
• Marianne Voll-Aanerud; Tomas Mikal Lind Eagan; Tore Wentzel-Larsen et al. (2008). Respiratory symptoms, COPD severity, and health related quality of life in a general population sample. (external link)

See a complete overview of publications in Cristin.

 

 

The Bergen COPD Microbiome Study (MicroCOPD)

The study aims to characterize the airways microbiome in patients with COPD, compared with healthy adults.

Secondary motives are to assess different bronchoscopic sampling techniques, to compare the microbiome within the lungs (upper versus lower airways, left versus right lung), the stability of the microbiome, and to study the impact of tobacco smoking and composition of the lower airways microbiome on development of COPD.

The pilot study was performed spring of 2012, data collection was performed 213-2015.16Sr DNA sequencing was performed in-house on the Illumina MiSeq platform. Several research papers have been published from this study, and already three bright PhD students (Einar Marius Martinsen, Christine Drengenes and Elise Leiten) have finalized their PhD projects with data from this study. Several more are underway.

The lung microbiome in interstitial lung disease Study (MicroILD)

This is an extension of the MicroCOPD study, with the aim to characterize the airways microbiome in patients undergoing evaluation for interstitial lung diseases. Data collection was performed 2014-2016, and 70 patients with ILDs were included, and papers on IPF and sarcoidosis have been published.

The lung microbiome in lung cancer study (MicroLC)

The final extension of the MicroCOPD study is per August 2023 in its pilot phase. We aim to examine how the pulmonary and gut microbiome influences risk of lung cancer, influence on treatment response and risk of treatment-related side effects.

The Bergen GeneCOPD follow-up study (GenKOLS follow-up)

The first Bergen GeneCOPD study was performed in 2002/04, where 500 COPD patients and healthy controls were assessed with a CT scan, lung function testing and clinical data, and gene wide association studies were performed. In 2014 the follow-up started, aiming to include 250 patients and 400 controls. The primary study question is the assessment of longitudinal change in COPD assessed by CT thorax, secondary motive is to assess risk factors for comorbid coronary heart disease. 

The Bergen COPD Cohort Study (BergenCOPD)

The study started in 2006 and ended in 2014. More than 400 COPD patients and 300 healthy controls were included, and most were attempted followed until the end of 2014, with annual clinical examinations.

The main research question was to search for predictors of later advers outcomes such as mortality, exacerbation frequency, development of cachexia and lung function decline. Almost 40 research papers are published from this study, and data from this study have been part of a number of PhD theses (Louise Persson, Eirunn Waatevik, Bernt Aarli, Bente Frisk, Marie Waatevik, Gunnar Husebø, Solveig Tangedal)