Optical imaging

IVIS Spectrum is an optical imaging system for small animals. The system detects photons in the visible range and is highly sensitive. The imager has space for 5 mice simultaneously and each scan can take up to a minute, maximizing the amount of specimens in pre-clinical studies.

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Optical imager and an optical image of mice.
IVIS optical imager and an optical image of two mice. Photo: MIC/Emmet McCormack

Further information

What is optical imaging

Optical imaging is based on detection of fluorescence and/or bioluminescence signal. It is a minimal- to non-invasive technique that enables the visualization of cancer cells in vivo, and can be used to follow disease progression in the animals over time to quantify the cancer burden. Bioluminescence imaging (BLI) is based on the expression of luciferase reporter gene in engineered cells.

Specifications

Model/Supplier:     IVIS Spectrum In Vivo Imaging System (PerkinElmer)

Application:            In vivo detection of near IR and GFP/Luminescent probes

System         Excitation            Emission           Application

IVIS                400-760                500-850             Bioluminescence & Fluorescence

Last updated: 02.06.2026