Obstructive sleep apnea and comorbidity: Treatment outcomes, influence on other sleep disorders, and the impact on inflammatory and metabolic biomarkers

In the present project we aim to address the associations between OSA and comorbid sleep disorders such as parasomnias, and inflammatory and metabolic biomarkers such as CRP, blood lipids and HbA1c in a large, clinical sample of patients with OSA. Moreover, we aim to address the effect of CPAP treatment on symptoms of insomnia in patients with OSA.

All patients undergo a diagnostic polygraphy, and blood samples including CRP, blood lipids and HbA1c (long term glucose marker) are collected. In addition, the patients complete a four-page comprehensive questionnaire covering most aspects of sleep medicine, including questions on parasomnias, insomnia, and comorbidities such as anxiety and depression. Furthermore, the register contains follow-up data from patients who have received CPAP treatment at the clinic.