Dagrun Slettebø Daltveit er senioringeniør ved Kjernefasiliteten for biostatistikk og dataanalyse, Fagområdet for epidemiologi og medisinsk statistikk, Institutt for global helse og samfunnsmedisin, Universitetet i Bergen (UiB). Hun er tilknyttet Senter for translasjonell forskning i epidemiologi (TRACE) og Forskningsgruppe for Livsstilsepidemiologi (LERG). Hun har en bachelorgrad i naturvitenskap (UiB), en mastergrad i statistikk - dataanalyse (UiB), og ph.d. fra det medisinske fakultet, UiB.

Hennes nåværende forskning er primært innen registerepidemiologi, og inkluderer blant annet arbeid med den globale byrden av leukemi, barnekreft og overlevelse i utviklingsland, kreftrisiko relatert til medfødte misdannelser, migrene, samt benzen eksponering.

Som en del av sin doktorgrad var hun på forskningsopphold fra desember 2022 til desember 2023 ved Cancer Surveilance Branch (CSU) ved International Agency for Research on Cancer (IARC), Verdens helseorganisasjon (WHO) i Lyon, Frankrike.

Populærvitenskapelig artikkel

• Økt kreftrisiko blant søsken til individer med medfødte misdannelser | UiB
• Medfødte misdannelser gir økt risiko for kreft, Aftenposten (2020). https://www.aftenposten.no/viten/i/OQyyLk/medfoedte-misdannelser-gir-oekt-risiko-for-kreft

Intervju

• Birth Defects Tied to Higher Cancer Risk, The New York Times (2020). https://www.nytimes.com/2020/12/07/well/live/birth-defects-cancer.html

Medieomtale

• Medfødte misdannelser og barnekreft - kjønnsforskjeller | Fagområde for epidemiologi og medisinsk statistikk | UiB
• Svangerskap og risiko for kreft i skjoldbruskkjertelen hos mor | Fagområde for epidemiologi og medisinsk statistikk | UiB
• Studie: Medfødte misdannelser gir økt risiko for kreft, Dagens Medisin (2020). https://www.dagensmedisin.no/artikler/2020/12/22/undersokte-kreftrisiko-hos-personer-med-medfodte-misdannelser/
• Medfødte misdannelser gir høyere risiko for å få kreft, også som voksne, UiB (2020).
• Medfødte misdannelser gir høyere risiko for å få kreft, også som voksne, Forskning.no (2020) https://forskning.no/forebyggende-helse-kreft-partner/medfodte-misdannelser-gir-hoyere-risiko-for-a-fa-kreft-ogsa-som-voksne/1779145
• Medfødte misdannelser øker risikoen for kreft også i voksen alder, FHI (2020). https://www.fhi.no/nyheter/2020/medfodte-misdannelser-oker-fisikoen-for-kreft-ogsa-i-voksen-alder/

 

 

2024

Fagansvarlig statistikk Methods in Global Health Research (INTH315), høst

Ko-fasilitator Workshop om Design and Analysis of Epidemiologic Studies for Causal Inference (Indian Council of Medical Research, National Institute of Epidemiology/UiB i Chennai, India), høst

Ko-fasilitator Experimental Epidemiology (INTH321A/INTH921), vår

Ko-fasilitator Design and analysis of epidemiologic studies for causal inference (CISMAC900-5 / CISMAC900A-5 ), vår

2022

Fagansvarlig statistikk Methods in Global Health Research (INTH315), H22.

Faglærer Epidemiologikurs i MED6, V22

Faglærer Epidemiologi (MEDEPI), V22

2021

Gruppelærer Analysis of longitudinal and correlated data (MEDSTA3), H21

Faglærer Epidemiologikurs i MED6, V21

Faglærer Epidemiologi (MEDEPI), V21

Gruppelærer Regresjonsmodellar i medisinsk forsking (MEDSTA2), V21

2010

Faglærer i matematikk, Sommerskolen Askøy vgs.

Undervisning i matematikk og fysikk for Vg1, Vg2 og Vg3 studiespesialisering, faglærer i matematikk for minoritetsspråklige og faglærer i matematikk for helse- og oppvekstfag, Olsvikåsen videregående

2009

Undervisning i matematikk og fysikk for Vg1, Vg2 og Vg3 studiespesialisering, Fana Gymnas.

Doktorgradsavhandling

• Daltveit , Dagrun Slettebø; Bjørge, Tone; Klungsøyr, Kari (2024). Birth defects and cancer risk: Nordic population-based studies of cancer risk in children, adolescents, and adults with major birth defects and their siblings. (ekstern lenke)

Vitenskapelig artikkel

• Daltveit , Dagrun Slettebø; Morgan, Eileen; Colombet, Murielle et al. (2024). Global patterns of leukemia by subtype, age, and sex in 185 countries in 2022. (ekstern lenke)
• Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2023). Cancer risk in the siblings of individuals with major birth defects: a large Nordic population-based case-control study. (ekstern lenke)
• Ridderseth, Hilde; Daltveit , Dagrun Slettebø; Hollund, Bjørg Eli et al. (2023). Benzene Exposure From Selected Work Tasks on Offshore Petroleum Installations on the Norwegian Continental Shelf, 2002-2018. (ekstern lenke)
• Ridderseth, Hilde; Daltveit , Dagrun Slettebø; Hollund, Bjørg Eli et al. (2023). Validation of a full-shift benzene exposure empirical model developed for work on offshore petroleum installations on the Norwegian continental shelf. (ekstern lenke)
• Ridderseth, Hilde; Daltveit, Dagrun Slettebø; Hollund, Bjørg Eli et al. (2022). Occupational Benzene Exposure in the Norwegian Offshore Petroleum Industry, 2002-2018. (ekstern lenke)
• Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2022). Sex differences in childhood cancer risk among children with major birth defects: a Nordic population-based nested case-control study. (ekstern lenke)
• Kitahara, Cari M.; Daltveit, Dagrun Slettebø; Ekbom, Anders et al. (2022). Maternal Health, Pregnancy and Offspring Factors, and Maternal Thyroid Cancer Risk: A Nordic Population-Based Registry Study. (ekstern lenke)
• Kitahara, Cari M; Slettebø, Dagrun Daltveit; Ekbom, Anders et al. (2020). Maternal health, in-utero, and perinatal exposures and risk of thyroid cancer in offspring: a Nordic population-based nested case-control study. (ekstern lenke)
• Daltveit , Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2020). Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults. (ekstern lenke)
• Husebø, Bettina; Ballard, Clive; Aarsland, Dag et al. (2019). The effect of a multicomponent intervention on quality of Life in residents of nursing homes: A randomized controlled trial (COSMOS). (ekstern lenke)
• van Dam, Paulien H; Caljouw, Monique A. A.; Slettebø, Dagrun Daltveit et al. (2019). Quality of Life and Pain Medication Use in Persons With Advanced Dementia Living in Long-Term Care Facilities. (ekstern lenke)
• Erdal, Ane; Slettebø, Dagrun Daltveit; Husebø, Bettina (2018). Authors’ Reply to Stefani: “Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicentre, Double-Blind, Placebo-Controlled Trial (DEP.PAIN.DEM)”. (ekstern lenke)
• Erdal, Ane; Flo, Elisabeth; Aarsland, Dag et al. (2018). Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicentre, Double-Blind, Placebo-Controlled Trial (DEP.PAIN.DEM). (ekstern lenke)
• Erdal, Ane; Flo, Elisabeth; Aarsland, Dag et al. (2018). Tolerability of buprenorphine transdermal system in nursing home patients with advanced dementia: a randomized, placebo-controlled trial (DEP.PAIN.DEM). (ekstern lenke)
• Erdal, Ane; Flo, Elisabeth; Selbæk, Geir et al. (2017). Associations between pain and depression in nursing home patients at different stages of dementia. (ekstern lenke)

Poster

• Daltveit , Dagrun Slettebø; Morgan, Eileen; Colombet, Murielle et al. (2023). Global patterns of leukemia in 2022: Incidence by subtype. (ekstern lenke)
• Daltveit , Dagrun Slettebø; Bjørge, Tone; Klungsøyr, Kari et al. (2022). Childhood cancer risk among children with major birth defects – sex differences?. (ekstern lenke)

Vitenskapelig foredrag

• Daltveit , Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2022). Cancer risk in individuals with siblings with major birth defects: A large Nordic population-based case-control study. (ekstern lenke)
• Daltveit , Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2021). Childhood cancer risk among individuals with major birth defects: A Nordic collaborative study. (ekstern lenke)
• Daltveit , Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders et al. (2020). Cancer risk in individuals with major birth defects: A large Nordic population-based case-control study among children, adolescents, and adults. (ekstern lenke)

Brev til redaktøren

• Kitahara, CM; Bjørge, Tone; Grotmol, Tom et al. (2021). Exposure to endocrine-disrupting chemicals in utero and thyroid cancer risk in offspring – Authors’ reply. (ekstern lenke)

Populærvitenskapelig artikkel

• Daltveit , Dagrun Slettebø; Engeland, Anders; Klungsøyr, Kari et al. (2020). Medfødte misdannelser gir økt risiko for kreft. (ekstern lenke)

Intervju

• Daltveit , Dagrun Slettebø (2020). Birth Defects Tied to Higher Cancer Risk. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

Selected publications

[1] Daltveit, D. S., Morgan E, Colombet M, Steliarova-Foucher E, Bendahhou K, Marcos-Gragera R, Rongshou Z, Smith A, Wei H, Soerjomataram I. (2024). Global patterns of leukemia by subtype, age, and sex in 185 countries in 2022. Leukemia.

[2] Daltveit, D. S., Klungsoyr, K., Engeland, A., Ekbom, A., Gissler, M., Glimelius, I., Grotmol, T., Madanat-Harjuoja, L., Ording, A. G., Saether, S. M. M., Sorensen, H. T., Troisi, R., & Bjorge, T. (2020). Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults. BMJ, 371, m4060.

[3] Daltveit, D. S., Klungsoyr, K., Engeland, A., Ekbom, A., Gissler, M., Glimelius, I., Grotmol, T., Madanat-Harjuoja, L., Ording, A. G., Sorensen, H. T., Troisi, R., & Bjorge, T. (2023). Sex differences in childhood cancer risk among children with major birth defects: a Nordic population-based nested case-control study. Int J Epidemiol, 52(2), 450-465.

[4] Daltveit, D. S., Klungsoyr, K., Engeland, A., Ekbom, A., Gissler, M., Glimelius, I., Grotmol, T., Madanat-Harjuoja, L., Ording, A. G., Sorensen, H. T., Troisi, R., & Bjorge, T. (2023). Cancer risk in the siblings of individuals with major birth defects: a large Nordic population-based case-control study. Int J Epidemiol.

[5] Kitahara, C. M., Slettebø Daltveit, D., Ekbom, A., Engeland, A., Gissler, M., Glimelius, I., Grotmol, T., Trolle Lagerros, Y., Madanat-Harjuoja, L., Männistö, T., Sørensen, H. T., Troisi, R., & Bjørge, T. (2021). Maternal health, in-utero, and perinatal exposures and risk of thyroid cancer in offspring: a Nordic population-based nested case-control study. Lancet Diabetes Endocrinol, 9(2), 94-105.

[6] Kitahara, C. M., Slettebø Daltveit, D., Ekbom, A., Engeland, A., Gissler, M., Glimelius, I., Grotmol, T., Trolle Lagerros, Y., Madanat-Harjuoja, L., Männistö, T., Sørensen, H. T., Troisi, R., & Bjørge, T. (2023). Maternal Health, Pregnancy and Offspring Factors, and Maternal Thyroid Cancer Risk: A Nordic Population-Based Registry Study. Am J Epidemiol, 192(1), 70-83.

[7] Ridderseth, Hilde; Daltveit, Dagrun Slettebø; Hollund, Bjørg Eli; Kirkeleit, Jorunn; Kromhout, H; Kruger, K; Austgulen, LT; Bråtveit, Magne. (2022). Occupational Benzene Exposure in the Norwegian Offshore Petroleum Industry, 2002-2018. Annals of Work Exposures and Health. 895-906.

[8] Ridderseth, Hilde; Daltveit , Dagrun Slettebø; Hollund, Bjørg Eli; Kirkeleit, Jorunn; Kromhout, Hans; Krüger, Kirsti; Aasbø, Kari; Bråtveit, Magne. (2023). Benzene Exposure From Selected Work Tasks on Offshore Petroleum Installations on the Norwegian Continental Shelf, 2002-2018. Annals of Work Exposures and Health. 228-240.

[9] Husebø, Bettina; Ballard, Clive; Aarsland, Dag; Selbæk, Geir; Slettebø, Dagrun Daltveit; Gulla, Christine; Aasmul, Irene; Habiger, Torstein Frugård; Elvegaard, Tony Matias; Testad, Ingelin; Flo, Elisabeth. (2019). The effect of a multicomponent intervention on quality of Life in residents of nursing homes: A randomized controlled trial (COSMOS). Journal of the American Medical Directors Association. 330-339.

[10] Erdal, Ane; Flo, Elisabeth; Selbæk, Geir; Aarsland, Dag; Bergh, Sverre; Slettebø, Dagrun Daltveit; Husebø, Bettina. (2017). Associations between pain and depression in nursing home patients at different stages of dementia. Journal of Affective Disorders. 8-14.

Ongoing projects

Understanding Headache Through Registry Data - A NorHEAD MiHEAD project (2024- )

The aim of the study is to improve the understanding and treatment of primary headache disorders by using multiple linked Norwegian registries and health surveys.

Role: Statistician. 

Exposure Assessment and Prevention of Death, Disease and Injuries among Offshore Petroleum Workers (2024-)

The aim of the work package in the study is to update job-exposure matrices for benzene and oil mist/vapour.

Role: Statistician. 

Childhood cancer survival in countries in transition (2023-)

In this project, we aim to produce survival estimates for childhood cancer in countries in transition. The work is carried out at the Cancer Surveillance Unit at the International Agency for Research on Cancer (IARC), World Health Organization (WHO), Lyon.

Role: Principal Investigator, UiB.

Global incidences and trends of leukemia (2023-)

In this project, we aim to estimate the global, regional, and national burden and trends of leukemia by subtype and age. The work is carried out at the Cancer Surveillance Unit at the International Agency for Research on Cancer (IARC), World Health Organization (WHO), Lyon.

Role: Principal Investigator, UiB. (https://doi.org/10.1038/s41375-024-02452-y)

Cancer risk in families with children with birth defects (2017-) 

In this project, we take advantage of large population-based registries in four Nordic countries to explore the relationship between birth defects and cancer risk in more detail, and more extensively, than previously done. Whether birth defect(s) is associated with cancer risk in the affected individual and their families is important for the understanding of the etiology of specific cancers and could possibly allow for identification of individuals at elevated risk who would benefit from more regular follow-up or subsequent clinical intervention (Paper I, Paper II, and Paper III).

Role: Statistician 2017-2021, PhD student 2021-2024.

Past projects

Development of job-exposure-models for risk assessment of benzene exposure (2017-2023)

The primary objective is to develop task- and job-exposure models to estimate benzene exposure by inhalation among the five job categories assumed to have the highest exposure at oil and gas processing installations (Paper I, Paper II, and Paper III).

Role: Statistician. 

Perinatal characteristics and thyroid cancer risk in mothers and offspring: a Nordic registry linkage study (2018-2022)

A Nordic birth and cancer registry linkage study to prospectively evaluate the associations of pregnancy complications and other perinatal characteristics with subsequent risk of thyroid cancer in women (subproject 1) and their offspring (subproject 2).  We hypothesize that benign thyroid disorders during pregnancy, particularly hypothyroidism (underactive thyroid) and perinatal characteristics related to or a consequence of underactive thyroid (e.g., preterm birth, gestational hypertension/preeclampsia, gestational diabetes, placental abruption) and/or altered sex steroid hormones during pregnancy (e.g., extreme birth weight, preterm birth, twin pregnancy, low birth order, hyperemesis, gestational hypertension/preeclampsia, pre-pregnancy and pregnancy weight and weight gain) are associated with increased risk of thyroid cancer in both mothers and their offspring (Paper I, and Paper II). 

Role: Statistician. 

The COSMOS intervention for improving the quality of life in nursing home patients study  (2016-2019)

The COSMOS project (COmmunication, Systematic pain assessment and treatment, Medication review, Organization of activities, and Safety) is a multicenter, cluster-randomized controlled trial aimed at improving the quality of life in nursing home patients. 545 patients from 67 nursing home units from the eastern and western parts of Norway were included in the study (Paper I, and Paper II).

Role: Statistician. 

The DEP.PAIN.DEM study - pain treatment and depression in nursing home patients (2016-2018)

The DEP.PAIN.DEM project is a multicentre, randomised, placebo-controlled trial which aims to determine whether pain treatment reduces symptoms of depression in nursing home patients with dementia and depression. 165 patients from 47 nursing homes in different regions of Norway were included in the study (Paper I, Paper II, and Paper III).

Role: Statistician.