More information available on the English language version of this page and following links.

Research

fly-facilities-in-Bergen

Drosophila as a model system

Want to get a students perspective of life in the fly lab?! Nora Solheim has got you covered!

https://biopraksis.w.uib.no/2022/04/06/hvordan-er-det-a-jobbe-med-drosophila/

 

https://www.bt.no/btmagasinet/i/9zy28q/bananfluer-hjelper-forskere-i-bergen-til-aa-forstaa-kreft-hos-mennesker

MOL200

MOL213

MOL220

 

Vitenskapelig artikkel

• Kjosavik, Malin Aure; Downham, Katherine Louise Powell; Styfhals, Ruth Hannah et al. (2025). The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in some animals. (ekstern lenke)
• Khezri, Rojyar; Holland, Petter; Schoborg, Todd Andrew et al. (2021). Host autophagy mediates organ wasting and nutrient mobilization for tumor growth. (ekstern lenke)
• O'Farrell, Fergal; Lobert, Viola; Sneeggen, Marte et al. (2017). Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.. (ekstern lenke)
• Katheder, Nadja Sandra; Khezri, Rojyar; O'Farrell, Fergal et al. (2017). Microenvironmental autophagy promotes tumour growth. (ekstern lenke)
• O'Farrell, Fergal; Lobert, Viola; Sneeggen, Marte et al. (2017). Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. (ekstern lenke)
• O'Farell, Fergal; Wang, Shenqiu; Katheder, Nadja Sandra et al. (2013). Two-Tiered Control of Epithelial Growth and Autophagy by the Insulin Receptor and the Ret-Like Receptor, Stitcher. (ekstern lenke)

Intervju

• Fladmark, Kari Espolin; O'Farrell, Fergal Michael (2024). De har gitt svar på flere medisinske gåter. Her er Bergens nye forsøksdyr.. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• O'Farell, Fergal; Rusten, Tor Erik; Stenmark, Harald Alfred (2013). Phosphoinositide 3-kinases as accelerators and brakes of autophagy. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

Károlyi D, Bótor SB, Neuhauser N, Péter M, Balogh G, O’Farrell F and Takáts S (2025) Fatty acid synthesis supports tumor progression through keeping TORC1 receptive for Insulin/PI3K signaling. bioRxiv:2025.02.19.639068. doi: 10.1101/2025.02.19.639068

Kjosavik MA, Garschall K and Steinmetz PRH (2024) The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in the sea anemone <em>Nematostella vectensis</em>. bioRxiv:2024.10.22.619599. doi: 10.1101/2024.10.22.619599

Khezri R, Holland P, Schoborg TA, Abramovic I, Takats S, Dillard C, Jain A, O’Farrell F et al. (2021) Host autophagy mediates organ wasting and nutrient mobilization for tumor growth. EMBO Journal. 2021 Jul 26:e107336. doi: 10.15252/embj.2020107336. Epub ahead of print. PMID: 34309071.

O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, et al. Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. Nature cell biology. 2017;19(12):1412-23. Epub 2017/10/31. DOI:10.1038/ncb3631. PubMed PMID:29084199.

Katheder NS, Khezri R*, O'Farrell F*, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE. (2017) Microenvironmental autophagy promotes tumour growth. Nature. Jan 19;541(7637):417-420. PMID: 28077876.

O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C (2013) Two-Tiered Control of Epithelial Growth and Autophagy by the Insulin Receptor and the Ret-like Receptor, Stitcher. PLoS Biol. 11(7):e1001612. PMCID: 3720245.

O'Farrell F, Rusten TE, Stenmark H (2013) Phosphoinositide 3-kinases as accelerators and brakes of autophagy. FEBS J 280: 6322-6337.

https://ofarrell.w.uib.no/research/