Vitenskapelig oversiktsartikkel/review

• Mukherjee, Sayani; Skrede, Silje; Fernø, Johan (2025). The hypothalamus as a therapeutic target: Towards novel approaches for managing antipsychotic-induced weight gain. (ekstern lenke)
• Pena-Leon, Veronica; Perez-Lois, Raquel; Villalon, Maria et al. (2024). Novel mechanisms involved in leptin sensitization in obesity. (ekstern lenke)
• Mukherjee, Sayani; Diéguez, Carlos; Fernø, Johan et al. (2023). Obesity wars: hypothalamic sEVs a new hope. (ekstern lenke)
• Mukherjee, Sayani; Skrede, Silje; Haugstøyl, Martha et al. (2023). Peripheral and central macrophages in obesity. (ekstern lenke)
• Al-Massadi, Omar; Parini, Paolo; Fernø, Johan et al. (2022). Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system. (ekstern lenke)
• Prida, Eva; Álvarez-Delgado, Sara; Pérez-Lois, Raquel et al. (2022). Liver Brain Interactions: Focus on FGF21 a Systematic Review. (ekstern lenke)
• Prida, Eva; Fernández-González, Sara; Pena-León, Verónica et al. (2022). Crosstalk between Melanin Concentrating Hormone and Endocrine Factors: Implications for Obesity. (ekstern lenke)
• Quiñones, Mar; Martínez-Grobas, Eva; Fernø, Johan et al. (2021). Hypothalamic Actions of SIRT1 and SIRT6 on Energy Balance. (ekstern lenke)
• Mukherjee, Sayani; Skrede, Silje; Milbank, Edward et al. (2021). Understanding the Effects of Antipsychotics on Appetite Control. (ekstern lenke)
• Dragano, Nathalia R.V.; Fernø, Johan; Diéguez, Carlos et al. (2020). Reprint of: Recent Updates on Obesity Treatments: Available Drugs and Future Directions. (ekstern lenke)
• Quiñones, Mar; Fernø, Johan; Al-Massadi, Omar (2020). Ghrelin and liver disease. (ekstern lenke)
• Dragano, Nathalia R.V.; Fernø, Johan; Diéguez, Carlos et al. (2020). Recent Updates on Obesity Treatments: Available Drugs and Future Directions. (ekstern lenke)
• Fernø, Johan; Strand, Kristina; Mellgren, Gunnar et al. (2019). Natural killer cells as sensors of adipose tissue stress. (ekstern lenke)
• Al-Massadi, Omar; Fernø, Johan; Dieguez, Carlos et al. (2019). Glucagon control on food intake and energy balance. (ekstern lenke)
• González-García, Ismael; Fernø, Johan; Diéguez, Carlos et al. (2017). Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance. (ekstern lenke)
• Tuduri, Eva; Imbernon, Monica; Hernández-Bautista, Rene Javier et al. (2017). Gpr55: A new promising target for metabolism?. (ekstern lenke)
• Lage, Ricardo; Fernø, Johan; Nogueiras, Rubén et al. (2016). Contribution of adaptive thermogenesis to the hypothalamic regulation of energy balance. (ekstern lenke)
• Massadi, Omar Al; López, Miguel; Fernø, Johan et al. (2015). What is the real relevance of endogenous ghrelin?. (ekstern lenke)
• Quiñones, Mar; Al-Massadi, Omar; Fernø, Johan et al. (2014). Cross-talk between SIRT1 and endocrine factors: Effects on energy homeostasis. (ekstern lenke)
• Morentin, Pablo Blanco Martínez De; Martinez-Sánchez, Noelia; Roa, Juan et al. (2014). Hypothalamic mTOR: the rookie energy sensor. (ekstern lenke)
• Martínez-Sánchez, Noelia; Alvarez, CV; Fernø, Johan et al. (2014). Hypothalamic effects of thyroid hormones on metabolism. (ekstern lenke)

Vitenskapelig artikkel

• Higa, Ryoko; Pourteymour, Shirin; Kolan, Pratibha Shrikant et al. (2025). Hepatic lipid metabolism is altered in Ubiad1+/- mice of both sexes. (ekstern lenke)
• Grymyr, Lisa Marie Dale; Mellgren, Gunnar; McCann, Adrian et al. (2024). Preoperative risk factors associated with left ventricular dysfunction after bariatric surgery. (ekstern lenke)
• Pena-Leon, V.; Perez-Lois, R.; Villalon, M. et al. (2023). Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans. (ekstern lenke)
• Meen, Astri Jeanette; Doncheva, Atanaska Ivanova; Böttcher, Yvonne et al. (2023). Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. (ekstern lenke)
• Haugstøyl, Martha; Cornillet, Martin; Strand, Kristina et al. (2023). Phenotypic diversity of human adipose tissue-resident NK cells in obesity. (ekstern lenke)
• Flølo, Tone Nygaard; Fosså, Alexander; Nedkvitne, Jonas Ingolf Petersson et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (ekstern lenke)
• Haugstøyl, Martha Eimstad; Cornillet, Martin; Strand, Kristina et al. (2022). Distinct T cell subsets in adipose tissue are associated with obesity. (ekstern lenke)
• Strand, Kristina; Stiglund, Natalie; Haugstøyl, Martha Eimstad et al. (2022). Subtype-specific surface proteins on adipose tissue macrophages and their association to obesity-induced insulin resistance. (ekstern lenke)
• Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander et al. (2022). Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy. (ekstern lenke)
• González-García, Ismael; Freire-Agulleiro, Óscar; Nakaya, Naoki et al. (2022). Olfactomedin 2 deficiency protects against diet-induced obesity. (ekstern lenke)
• Fraga, Angela; Rial-Pensado, Eva; Nogueiras, Rubén et al. (2021). Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK. (ekstern lenke)
• Doncheva, Atanaska Ivanova; Norheim, Frode Amador; Hjorth, Marit et al. (2021). Serglycin Is Involved in Adipose Tissue Inflammation in Obesity. (ekstern lenke)
• Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, Andre et al. (2021). Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance. (ekstern lenke)
• Gonzalez-Rellan, Maria J.; Fondevila, Marcos F.; Fernandez, Uxia et al. (2021). O-GlcNAcylated p53 in the liver modulates hepatic glucose production. (ekstern lenke)
• Capelli, Valentina; Grijota-Martínez, Carmen; Dragano, Nathalia R. V. et al. (2021). Orally induced hyperthyroidism regulates hypothalamic amp-activated protein kinase. (ekstern lenke)
• Quiñones, Mar; Hernandez-Bautista, Rene; Beiroa, Daniel et al. (2021). Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner. (ekstern lenke)
• Seoane-Collazo, Patricia; Romero-Picó, Amparo; Rial-Pensado, Eva et al. (2021). κ-opioid signaling in the lateral hypothalamic area modulates nicotine-induced negative energy balance. (ekstern lenke)
• Quiñones, Mar; Fernø, Johan; Dieguez, Carlos et al. (2019). Exciting advances in GPCR-based drugs discovery for treating metabolic disease and future perspectives. (ekstern lenke)
• Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård et al. (2019). Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. (ekstern lenke)
• Stiglund, Natalie; Strand, Kristina; Cornillet, Martin et al. (2019). Retained NK cell phenotype and functionality in non-alcoholic fatty liver disease. (ekstern lenke)
• Gudbrandsen, Oddrun Anita; Dankel, Simon N; Skumsnes, Lillian et al. (2019). Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis. (ekstern lenke)
• Gonzalez-Garcia, Ismael; Contreras, Cristina; Estévez-Salguero, Ánxela et al. (2018). Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. (ekstern lenke)
• Romero-Picó, Amparo; Sanchez-Rebordelo, Estrella; Imbernon, Monica et al. (2018). Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake. (ekstern lenke)
• Porteiro, Begoña; Fondevila, Marcos F.; Buque, Xabier et al. (2018). Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. (ekstern lenke)
• Quiñones, Mar; Al-Massadi, Omar; Folgueira, Cintia et al. (2018). p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. (ekstern lenke)
• Barja-Fernandez, Silvia; Moreno-Navarrete, Jose Maria; Folgueira, Cintia et al. (2018). Plasma ANGPTL-4 is Associated with Obesity and Glucose Tolerance: Cross-Sectional and Longitudinal Findings. (ekstern lenke)
• González-García, Ismael; Morentin, Pablo B. Martínez de; Estévez-Salguero, Ánxela et al. (2018). mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol. (ekstern lenke)
• Contreras, Cristina; González-García, Ismael; Seoane-Collazo, Patricia et al. (2017). Reduction of hypothalamic endoplasmic reticulum stress activates browning of white fat and ameliorates obesity. (ekstern lenke)
• Porteiro, Begoña; Fondevila, Marcos F.; Delgado, Teresa C. et al. (2017). Hepatic p63 regulates steatosis via IKK?/ER stress. (ekstern lenke)
• Martínez-Sánchez, Noelia; Moreno-Navarrete, José M.; Contreras, Cristina et al. (2017). Thyroid hormones induce browning of white fat. (ekstern lenke)
• González-García, Ismael; Fernø, Johan; López, Miguel (2017). Central oxytocin and energy balance: More than feelings. (ekstern lenke)
• Skrede, Silje; Gonzalez-Garcia, Ismael; Martins, Luis et al. (2017). Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. (ekstern lenke)
• Ejarque, Miriam; Borlaug, Marianne; Vilarrasa, Núria et al. (2017). Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery. (ekstern lenke)
• Imbernon, Monica; Sanchez-Rebordelo, Estrella; Romero-Picó, Amparo et al. (2016). Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress. (ekstern lenke)
• Steen, Vidar Martin; Skrede, Silje; Polushina, Tatiana et al. (2016). Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. (ekstern lenke)
• Tuduri, Eva; Beiroa, Daniel; Stegbauer, Johannes et al. (2016). Acute stimulation of brain mu opioid receptors inhibits glucose-stimulated insulin secretion via sympathetic innervation. (ekstern lenke)
• Folgueira, Cintia; Beiroa, Daniel; Callon, Aurelie et al. (2016). Uroguanylin action in the brain reduces weight gain in obese mice via different efferent autonomic pathways. (ekstern lenke)
• Contreras, Cristina; Gonzalez, Francisco; Fernø, Johan et al. (2015). The brain and brown fat. (ekstern lenke)
• Morentin, Pablo Blanco Martínez De; Lage, Ricardo; Gonzalez-Garcia, Ismael et al. (2015). Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-COA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. (ekstern lenke)
• Fernø, Johan; Señaris, Rosa; Diéguez, Carlos et al. (2015). Orexins (hypocretins) and energy balance: More than feeding. (ekstern lenke)
• Quiñones, Mar; Al-Massadi, Omar; Gallego, Rosalía et al. (2015). Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance. (ekstern lenke)
• Fernø, Johan; Ersland, Kari Merete; Duus, Inger Hødnebø et al. (2015). Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. (ekstern lenke)
• Seoane-Collazo, Patricia; Fernø, Johan; Gonzalez, Francisco et al. (2015). Hypothalamic-autonomic control of energy homeostasis. (ekstern lenke)
• Lage, Ricardo; Parisi, Claudia; Seoane-Collazo, Patricia et al. (2015). Lack of hypophagia in CB1 null mice is associated to decreased Hypothalamic POMC and CART. (ekstern lenke)
• Beiroa, Daniel; Imbernon, Monica; Gallego, Rosalía et al. (2014). GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. (ekstern lenke)
• Seoane-Collazo, Patricia; Morentin, Pablo Blanco Martínez De; Fernø, Johan et al. (2014). Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. (ekstern lenke)
• Skrede, Silje; Martins, Luis; Berge, Rolf Kristian et al. (2014). Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. (ekstern lenke)
• Skrede, Silje; Steen, Vidar Martin; Fernø, Johan (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (ekstern lenke)
• Jassim, Goran; Skrede, Silje; Vázquez, Maria Jesús et al. (2012). Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. (ekstern lenke)
• Skrede, Silje; Fernø, Johan; Vázquez, Maria Jesús et al. (2012). Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. (ekstern lenke)
• Skrede, Silje; Fernø, Johan; Bjørndal, Bodil et al. (2012). Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. (ekstern lenke)
• Morentin, Pablo B.Martinez de; Whittle, Andrew J.; Fernø, Johan et al. (2012). Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. (ekstern lenke)
• Osland, Teresa Maria; Fernø, Johan; Håvik, Bjarte et al. (2011). Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. (ekstern lenke)
• Fernø, Johan; Varela, Luis; Skrede, Silje et al. (2011). Olanzapine-induced hyperphagia and weight gain associate with crexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. (ekstern lenke)
• Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2011). Lipogenic effects of psychotropic drugs: focus on the SREBP system. (ekstern lenke)
• Jassim, Goran; Fernø, Johan; Theisen, Frank M. et al. (2011). Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. (ekstern lenke)
• Hellard, Stephanie Le; Mühleisen, Thomas W.; Djurovic, Srdjan et al. (2010). Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. (ekstern lenke)
• Vik-Mo, Audun Osland; Fernø, Johan; Skrede, Silje et al. (2009). Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. (ekstern lenke)
• Hellard, Stephanie Le; Theisen, Frank M.; Haberhausen, Michael et al. (2009). Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?. (ekstern lenke)
• Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran et al. (2009). Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. (ekstern lenke)
• Vik-Mo, Audun Osland; Birkenæs, Astrid B.; Fernø, Johan et al. (2008). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (ekstern lenke)
• Hellard, Stephanie Le; Theisen, F.M.; Haberhausen, M et al. (2008). Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: pertubation of SREBP-controlled lipogenesis in drug-realted metabolic adverse effects?. (ekstern lenke)
• Hellard, S Le; Muhleisen, TW; Djurovic, Srdjan et al. (2008). Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. (ekstern lenke)
• Vik-Mo, AO; Birkenæs, Astrid Brate; Fernø, J et al. (2008). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (ekstern lenke)
• Ræder, Maria Therese Barøy; Fernø, Johan; Vik-Mo, Audun Osland et al. (2006). SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: Relevance for metabolic side-effects?. (ekstern lenke)
• Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland et al. (2006). Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs. (ekstern lenke)
• Ræder, Maria Therese Barøy; Fernø, Johan; Glambek, Marte et al. (2006). Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. (ekstern lenke)
• Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland et al. (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. (ekstern lenke)

Poster

• Vinnes, Erik Wilhelm; Aakre, Kristin Moberg; Fernø, Johan et al. (2024). Long-term effect of bariatric surgery on circulating GDF15 concentrations. (ekstern lenke)
• Fernø, Johan; Willems, Aron; Dankel, Simon N et al. (2014). SLC7A10, a novel adipocyte-enriched gene with a potential role in adipocyte differentiation. (ekstern lenke)

Vitenskapelig foredrag

• Flølo, Tone Nygaard; Fosså, Alexander; Waage, Jo Erling Riise et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (ekstern lenke)

Populærvitenskapelig artikkel

• Haugstøyl, Martha Eimstad; Fernø, Johan (2017). GPR55 - en ny reseptor for behandling av metabolsk sykdom?. (ekstern lenke)

Leder

• Skrede, Silje; Fernø, Johan; Steen, Vidar Martin (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (ekstern lenke)

Sammendrag/Abstract

• Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran et al. (2008). Effect of clozapine on memory function in the hippocampal lesion model of schizophrenia. (ekstern lenke)
• Vik-Mo, Audun Osland; Fernø, Johan; Steen, Vidar Martin (2008). Differential effects of antipsychotic drugs on ATP-binding cassette type A1 (ABCA1) and apolipoprotein E (ApoE) gene expression in cultured cells. (ekstern lenke)
• Vik-Mo, Audun Osland; Birkenæs, Astrid B.; Fernø, Johan et al. (2007). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (ekstern lenke)
• Vik-Mo, Audun Osland; Fernø, Johan; Ræder, Maria et al. (2006). Antipsychotic and antidepressive drugs regulate the expression of apolipoprotein E. (ekstern lenke)

Doktorgradsavhandling

• Fernø, Johan; Steen, Vidar Martin (2007). Lipogenic effects of antipsychotic drugs in cultured cells and in rat. (ekstern lenke)

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