Postdoctoral fellow in the Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway

The main focus of the Postdoc project is to study the T and B-cell immunity after influenza vaccination and/or infection in humans.

01.09.2008 - 30.06.2013

Ph.D. 

University of Chinese Academy of Sciences

Graduated from Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China

Leserbrev

• Kristin Greve-Isdahl Mohn; Geir Bredholt; Therese Bredholt Onyango et al. (2023). SARS-CoV-2 infection induces long-lived B and T-cell responses up to 15 months post-infection, irrespective of disease severity. (ekstern lenke)

Vitenskapelig artikkel

• Therese Bredholt Onyango; Fan Zhou; Geir Bredholt et al. (2023). SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients. (ekstern lenke)
• Joanna Waldock; Edmond J. Remarque; Lingyi Zheng et al. (2023). Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study. (ekstern lenke)
• Karl Albert Brokstad; Marita Fredriksen; Fan Zhou et al. (2018). T follicular-like helper cells in the peripheral blood of patients with primary Sjögren's syndrome. (ekstern lenke)
• Johanna Eva Bodin; Gro Tunheim; Anja Bråthen Kristoffersen et al. (2025). High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza. (ekstern lenke)
• Mai Chi Trieu; Fan Zhou; Sarah Larteley Lartey Jalloh et al. (2016). Long-term maintenance of the influenza-specific cross-reactive memory CD4+ T-cell responses following repeated annual influenza vaccination.. (ekstern lenke)
• Nina Urke Ertesvåg; Julie Xiao; Fan Zhou et al. (2022). A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern. (ekstern lenke)
• Julie Zimmermann; Signe Tandrup Schmidt; Ramona Trebbien et al. (2022). A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease. (ekstern lenke)
• Mai Chi Trieu; Amit Bansal; Anders Madsen et al. (2020). SARS-CoV-2-specific neutralizing antibody responses in Norwegian healthcare workers after the first wave of COVID-19 pandemic: a prospective cohort study. (ekstern lenke)
• Camilla Tvedt Ekanger; Nilima Dinesh Kumar; Rosanne W. Koutstaal et al. (2025). Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies. (ekstern lenke)
• Camilla Tvedt Ekanger; Fan Zhou; Dana Bohan et al. (2022). Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 respiratory virus. (ekstern lenke)
• Lena Hansen; Karl Albert Brokstad; Amit Bansal et al. (2023). Durable immune responses after BNT162b2 vaccination in home-dwelling old adults. (ekstern lenke)
• Sarah Larteley Lartey; Rishi Pathirana; Fan Zhou et al. (2015). Single dose vaccination of the ASO3-adjuvanted A (H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains. (ekstern lenke)
• Sehee Rim; Sunniva Todnem Sakkestad; Fan Zhou et al. (2023). Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. (ekstern lenke)
• Bjørn Blomberg; Kristin Greve-Isdahl Mohn; Karl Albert Brokstad et al. (2021). Long COVID in a prospective cohort of home-isolated patients. (ekstern lenke)
• Nina Urke Ertesvåg; Sunniva Todnem Sakkestad; Fan Zhou et al. (2022). Persistent Fever and Positive PCR 90 Days Post-SARS-CoV-2 Infection in a Rituximab-Treated Patient: A Case of Late Antiviral Treatment. (ekstern lenke)
• Sarah Larteley Lartey Jalloh; Fan Zhou; Karl Albert Brokstad et al. (2020). Live-attenuated influenza vaccine induces tonsillar follicular T helper cell responses that correlate with antibody induction. (ekstern lenke)
• Thor Ueland; Rebecca Jane Cox; Annika Elisabet Michelsen et al. (2025). Markers of T cell activation and exhaustion in plasma are associated with persistent symptoms up to 18 months following mild SARS-CoV-2 infection. (ekstern lenke)
• Anette Susanne Bøe Wolff; Lena Hansen; Marianne Aardal Grytaas et al. (2023). Vaccination prevents severe COVID-19 outcome in patients with neutralizing type 1 interferon autoantibodies. (ekstern lenke)
• Håkon Amdam; Anders Madsen; Fan Zhou et al. (2021). Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014). (ekstern lenke)
• Tor Kristian Andersen; Fan Zhou; Rebecca Jane Cox et al. (2017). A DNA vaccine that targets hemagglutinin to antigen-presenting cells protects mice against H7 influenza. (ekstern lenke)
• Juan Manuel Carreño; Jacqueline U. McDonald; Tara Hurst et al. (2020). Development and assessment of a pooled serum as candidate standard to measure influenza a virus group 1 hemagglutinin stalk-reactive antibodies. (ekstern lenke)
• Hongxing Hu; Fan Zhou; Xiaoli Ma et al. (2025). Targeted barcoding of variable antibody domains and individual transcriptomes of the human B-cell repertoire using Link-Seq. (ekstern lenke)
• Shahinul Islam; Kristin Greve Isdahl Mohn; Florain Krammer et al. (2017). Influenza A haemagglutinin specific IgG responses in children and adults after seasonal trivalent live attenuated influenza vaccination. (ekstern lenke)
• Shahinul Islam; Fan Zhou; Sarah Larteley Lartey Jalloh et al. (2019). Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination. (ekstern lenke)
• Elisabeth Berg Fjelltveit; Bjørn Blomberg; Kanika Kuwelker et al. (2022). Symptom Burden and Immune Dynamics 6 to 18 Months Following Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection (SARS-CoV-2): A Case-control Study. (ekstern lenke)
• Mai Chi Trieu; Fan Zhou; Sarah Larteley Lartey Jalloh et al. (2018). Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years. (ekstern lenke)
• Kanika Kuwelker; Fan Zhou; Bjørn Blomberg et al. (2021). Attack rates amongst household members of outpatients with confirmed COVID-19 in Bergen, Norway: A case-ascertained study. (ekstern lenke)
• Fan Zhou; Juha Vahokoski; Siri Øyen et al. (2024). Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection. (ekstern lenke)
• Lena Hansen; Fan Zhou; Håkon Amdam et al. (2021). Repeated Influenza Vaccination Boosts and Maintains H1N1pdm09 Neuraminidase Antibody Titers. (ekstern lenke)
• Fan Zhou; Lena Hansen; Gabriel Kristian Pedersen et al. (2021). Matrix M Adjuvanted H5N1 Vaccine Elicits Broadly Neutralizing Antibodies and Neuraminidase Inhibiting Antibodies in Humans That Correlate With In Vivo Protection. (ekstern lenke)
• Trung Tran; Eline Benno Vaage; Adi Mehta et al. (2022). Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants. (ekstern lenke)
• Federica Sicca; Eleni Sakorafa; Anouk de Jonge et al. (2022). The evolution of humoral immune responses to past and novel influenza virus strains gives evidence for antigenic seniority. (ekstern lenke)
• Anders Madsen; Linda Azimi; Sarah Tete et al. (2019). No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination. (ekstern lenke)
• Marie-Clotilde Bernard; Joanna Waldock; Sylvie Commandeur et al. (2022). Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study. (ekstern lenke)
• Geir Bredholt; Marianne Sævik; Hanne Søyland et al. (2024). Three doses of Sars-CoV-2 mRNA vaccine in older adults result in similar antibody responses but reduced cellular cytokine responses relative to younger adults. (ekstern lenke)
• Martin Beukema; Shuran Gong; Kasem Al-Jaawni et al. (2023). Prolonging the delivery of influenza virus vaccine improves the quantity and quality of the induced immune responses in mice. (ekstern lenke)
• Kristin Greve-Isdahl Mohn; Geir Bredholt; Fan Zhou et al. (2022). Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients. (ekstern lenke)
• Lukas Anders Kryger Hoen; Sarah Larteley Lartey Jalloh; Fan Zhou et al. (2024). Impact of Pre-Existing Immunity and Age on Antibody Responses to Live Attenuated Influenza Vaccine. (ekstern lenke)
• Monica Trondsen; Lara Adnan Aqrawi; Fan Zhou et al. (2015). Induction of local secretory IgA and multifunctional CD4+ T-helper cells following intranasal immunization with a H5N1 whole inactivated influenza virus vaccine in BALB/c mice. (ekstern lenke)
• Kristin Greve Isdahl Mohn; Fan Zhou; Karl Albert Brokstad et al. (2017). Boosting of cross-reactive and protection-associated T cells in children after live attenuated influenza vaccination. (ekstern lenke)
• Mai Chi Trieu; Åsne Jul-Larsen; Marianne Sævik et al. (2018). Antibody responses to influenza A/H1N1pdm09 virus after pandemic and seasonal influenza vaccination in healthcare workers: A 5-year follow-up study. (ekstern lenke)
• Amit Bansal; Mai Chi Trieu; Emily M. Eriksson et al. (2025). SARS-CoV-2 infection rates and associated risk factors in healthcare workers: systematic review and meta-analysis. (ekstern lenke)

Konferanseposter

• Camilla Tvedt Ekanger; Fan Zhou; Karl Albert Brokstad et al. (2024). Comparison of Air-Liquid Interface and Organoid Airway Models for Human Respiratory Virus Infection Studies. (ekstern lenke)
• Fan Zhou; Juha Vahokoski; Nina Langeland et al. (2022). Kinetics of seasonal and pandemic human coronavirus reactive antibodies after repeated vaccinations in adults and the elderly. (ekstern lenke)
• Sehee Rim; Sunniva Todnem Sakkestad; Jørn Skavland et al. (2018). Comprehensive characterization of circulating T follicular helper cells and plasmablasts in human volunteers experimentally infected with enterotoxigenic Escherichia coli. (ekstern lenke)
• Fan Zhou; Rishi Delan Pathirana; Sarah Larteley Lartey Jalloh et al. (2015). Follicular helper T cell responses in children and adults after vaccination with seasonal 2013-14 live attenuated influenza vaccine. (ekstern lenke)
• Fan Zhou; Rishi Delan Pathirana; Sarah Larteley Lartey Jalloh et al. (2016). Follicular helper T cell responses in children and adults after vaccination with seasonal 2013-14 live attenuated influenza vaccine. (ekstern lenke)
• Lukas Anders Kryger Hoen; Camilla Tvedt Ekanger; Fan Zhou et al. (2024). Influenza A Variants Formed During Lung Organoid Infection In The Presence of Humoral Immunity. (ekstern lenke)
• Lena Hansen; Fan Zhou; Håkon Amdam et al. (2019). Neuraminidase antibody responses after pandemic and seasonal influenza vaccinations: a five-year study. (ekstern lenke)
• Fan Zhou; Lena Hansen; Tor Kristian Andersen et al. (2019). Adjuvanted H5N1 vaccine elicits rapid and multifaceted humoral immune responses in human. (ekstern lenke)
• Fan Zhou; Rishi Delan Pathirana; Sarah Larteley Lartey Jalloh et al. (2024). Phenotypic and functional changes of human follicular T helper cells over decades of life. (ekstern lenke)
• Lena Hansen; Fan Zhou; Rebecca Jane Cox (2019). Neuraminidase Antibody Responses After Pandemic And Seasonal Vaccination: A Five-Year Study. (ekstern lenke)
• Fan Zhou; Steffen Aleksander Slettevoll; Sarah Larteley Lartey Jalloh et al. (2017). Live attenuated in+luenza vaccine elicits superior follicular T help cell and local antibody responses in children. (ekstern lenke)
• Fan Zhou; Lena Hansen; Gabriel Pedersen et al. (2022). Matrix M adjuvanted H5N1 vaccine elicits broadly neutralizing antibodies and neuraminidase inhibiting antibodies in humans that correlate with in vivo protection. (ekstern lenke)
• Lukas Anders Kryger Hoen; Sarah Larteley Lartey Jalloh; Kristin Greve-Isdahl Mohn et al. (2023). A Comparison of Humoral Responses Induced Following Live Attenuated Influenza Vaccination in Children and Adults. (ekstern lenke)
• Fan Zhou; Rishi Delan Pathirana; Sarah Larteley Lartey Jalloh et al. (2016). Age related decline of T follicular helper cells in children and adults. (ekstern lenke)

Rettelse i tidsskrift

• Mai Chi Trieu; Fan Zhou; Sarah Larteley Lartey Jalloh et al. (2018). Publisher Correction: Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years. (ekstern lenke)
• Trung Tran; Eline Benno Vaage; Adi Mehta et al. (2023). Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants (npj Vaccines, (2022), 7, 1, (174), 10.1038/s41541-022-00586-7). (ekstern lenke)

Konferanseforedrag

• Amit Bansal; Mai Chi Trieu; Anders Madsen et al. (2020). Antibody responses to SARS-CoV-2 virus in Norwegian health-care workers: an observational prospective cohort study. (ekstern lenke)
• Sehee Rim; Sunniva Todnem Sakkestad; Fan Zhou et al. (2022). Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. (ekstern lenke)
• Amit Bansal; Mai Chi Trieu; Anders Madsen et al. (2020). Low infection and seroconversion rates in frontline healthcare workers during the peak of the Coronavirus disease 2019 pandemic in Bergen, Norway. (ekstern lenke)
• Amit Bansal; Mai Chi Trieu; Anders Madsen et al. (2020). SARS-COV-2-Specific neutralising antibody responses in Norwegian healthcare workers after the first wave of COVID-19 pandemic: a prospective cohort study. (ekstern lenke)
• Sehee Rim; Sunniva Todnem Sakkestad; Fan Zhou et al. (2019). Comprehensive characterization and kinetics of circulating lymphocytes in human volunteers experimentally infected with enterotoxigenic Escherichia coli. (ekstern lenke)
• Kristin Greve Isdahl Mohn; Rebecca Jane Cox; Fan Zhou et al. (2015). Cellular immune responses after live attenuated influenza vaccination in children, a clinical trial.. (ekstern lenke)
• Fan Zhou; Juha Vahokoski; Florian Krammer et al. (2023). Age related differences in kinetics and magnitude of SARS-CoV-2 and endemic human coronavirus reactive antibody responses after vaccination and infection. (ekstern lenke)

Vitenskapelig litteraturgjennomgang

• Fan Zhou; Mai Chi Trieu; Richard Allan Davies et al. (2018). Improving influenza vaccines: challenges to effective implementation. (ekstern lenke)
• Kristin Greve Isdahl Mohn; Fan Zhou (2018). Clinical expectations for better influenza virus vaccines - perspectives from the young investigators' point of view. (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

1. To characterized in-depth the de novo SARS-CoV-2 specific antibody responses and the boosting of HCoV-reactive antibodies after SARS-CoV-2 vaccination and infection.

2. To assess the magnitude and breadth of immuntiy towards the emerging highly pathogenic avian H5N1 influenza virus.

3. To study the influenza and RSV specific immune responses in vaccination and/or infected individuals.