Jeg har siden 1988 forsket primært på sarkomer, kreft i binde- og støttevev. I de senere år har vi fokusert på barnekreft.

Multiple talks, interviews and articles directed to the public, decision makers and politicians.

Established the CCBIO906 Course in Cancer Genomics

Deltakelse i radio eller TV

• Ola Myklebost; Per Eystein Lønning; Anne Lise Ryel et al. (2016). Persontilpasset kreftmedisin – et spørsmål om prioritering. (ekstern lenke)
• Ola Myklebost; Per Eystein Lønning; Ole Alexander Opdalshei et al. (2016). På vei mot en klassedelt kreftomsorg?. (ekstern lenke)

Doktorgradsavhandling

• Robert Hanes; Ola Myklebost; Leonardo A Meza-Zepeda et al. (2018). Precision medicine for the treatment of a highly malignant and resistant type of liposarcoma. (ekstern lenke)
• Isabelle Budin Ljøsne; Jan Helge Solbakk; Jennifer Ruth Harris et al. (2018). Bringing personalized medicine to people. (ekstern lenke)
• Stine Henrichson Kresse; Ola Myklebost (2008). Chromosomal aberrations in human sarcomas identified using genomic microarrays. (ekstern lenke)

Forelesning

• Ola Myklebost (2015). ”Cancer Who-done-it”. (ekstern lenke)

Fremhevet artikkel i media

• Steinar Aamdal; Heidi Beate Bentzen; Ole Johan Borge et al. (2017). Åpne Nordens grenser for forskning og behandling. (ekstern lenke)
• Ola Myklebost; Ragnhild A Lothe; Bjørn Tore Gjertsen et al. (2015). Bør hver kreftpasient bli et eget forskningsprosjekt?. (ekstern lenke)
• Rolf Inge Skotheim; Leonardo Andrés Meza-Zepeda; Eivind Hovig et al. (2012). Genomsekvensering for persontilpasset kreftbehandling. (ekstern lenke)

Kapittel i populærvitenskapelig bok

• Ola Myklebost (2015). Gener og kreft. (ekstern lenke)
• Ola Myklebost (2009). Stamcellenes mørke side. (ekstern lenke)

Konferanseabstrakt

• Baoyan Bai; Daniel Vodák; Sigve Nakken et al. (2019). Deep profiling of genetic aberrations and clonal evolution in follicular lymphoma. (ekstern lenke)
• Kristine Misund; Davine Hofste op Bruinink; Eivind Coward et al. (2018). Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. (ekstern lenke)
• Rolf Inge Skotheim; Torfinn Nome; Gard O Sundby Thomassen et al. (2012). Identification of Fusion Transcripts in Colorectal Cancer by Combined RNA-seq and Exon Microarray Analyses. (ekstern lenke)
• Heidi Maria Namløs; Stine Henrichson Kresse; Ingrid Helene Garmann Østensen et al. (2010). Integrated analysis reveals overexpression of miRNA clusters in osteosarcomas. (ekstern lenke)
• Stine Henrichson Kresse; Halfdan Rydbeck; Ana Heslanyeth Barragan Polania et al. (2010). Integrative analysis of genome-wide genetic and epigenetic changes in human osteosarcomas. (ekstern lenke)
• T Baroy; Dahlia Hopmeier; Stine Henrichson Kresse et al. (2010). Characterisation of LSAMP, a novel candidate tumour suppressor gene in osteosarcomas. (ekstern lenke)

Konferanseforedrag

• Kristine Misund; Davine Hofste op Bruinink; Eivind Coward et al. (2018). Clonal Evolution of Multiple Myeloma After Treatment with Novel Agents. (ekstern lenke)
• Kristine Misund; Davine Hofste op Bruinink; Eivind Coward et al. (2017). Detection of mutations in Multiple Myeloma during different stages of disease. (ekstern lenke)
• Ola Myklebost (2017). Sarcomas: Genomic Landscape and potential targets.. (ekstern lenke)
• Ola Myklebost (2012). Personalized cancer medicine. (ekstern lenke)

Konferanseposter

• Kristine Misund; Davine Hofste op Bruinink; Eivind Coward et al. (2018). Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. (ekstern lenke)
• Eivind Coward; Kristine Misund; Davine Hofste op Bruinink et al. (2017). Exome sequencing of multiple myeloma at sequential time points. (ekstern lenke)
• Marianne Stabell; Åshild Skarshaug Breivik; Ola Myklebost (2010). Lysine methylation of HMGA2 by the monomethyltransferase Set7/9. (ekstern lenke)

Leserbrev

• Isabelle Budin Ljøsne; Heidi Beate Bentzen; Jan Helge Solbakk et al. (2015). Genomsekvensering i forskning krever ny tilnærming til samtykke. (ekstern lenke)

Medieintervju

• Eva Wessel Stratford; Ola Myklebost (2016). Vil behandle sjeldne kreftformer med personlig medisinering. (ekstern lenke)
• Ola Myklebost (2015). “Helseforetakene driver beskyttede industribedrifter” Om svak satsing på fagutvikling og utprøvende behandling.. (ekstern lenke)
• Ola Myklebost (2015). Ny studie: Flaks eller uflaks bestemmer oftest om du får kreft – ikke usunn livsstil.Tilfeldige mutasjoner i DNA står bak to av tre krefttilfeller.. (ekstern lenke)
• Ola Myklebost (2015). ”It’s All About the Genome”. (ekstern lenke)
• Ola Myklebost (2015). ”Jakten på en kreftkur”. (ekstern lenke)
• Ola Myklebost (2014). Muligheter med livets strekkkode. (ekstern lenke)
• Ola Myklebost (2014). "Dødstest" kan forusi risiko for å dø i løpet av fem år. (ekstern lenke)
• Ola Myklebost (2014). En ny generasjon kreftmedisin. (ekstern lenke)
• Ola Myklebost (2013). Storsatsing på bedre kreftbehandling. (ekstern lenke)
• Ola Myklebost (2013). Beregner seg frem til ny kreftbehandling. (ekstern lenke)
• Ola Myklebost (2013). Kreftforskning; Kan kampen vinnes?. (ekstern lenke)
• Ola Myklebost (2013). Kartlegger kreftgenene. (ekstern lenke)
• Ola Myklebost (2012). Norway invests in personalized cancer care. (ekstern lenke)
• Ola Myklebost (2012). Når gener skrus av og på. (ekstern lenke)
• Ola Myklebost; Ragnhild A. Lothe (2012). Persontilpasset kreftbehandling. (ekstern lenke)
• Ola Myklebost (2012). Intervju om medisinske gjennombrudd. (ekstern lenke)
• Ola Myklebost (2012). Persontilpasset kreftmedisin. (ekstern lenke)
• Ola Myklebost (2012). Om Norsk Kreftgenomikkonsortium. (ekstern lenke)
• Ola Myklebost (2012). På vei mot persontilpasset kreftmedisin. (ekstern lenke)
• Ola Myklebost (2012). Norway to bring cancer tests to the clinic. (ekstern lenke)
• Ola Myklebost (2012). Reading cancer's blueprint. (ekstern lenke)
• Ola Myklebost (2012). Skal kartleggja kreftgenar hos 4000 nordmenn. (ekstern lenke)
• Ola Myklebost (2012). Intervju om persontilpasset kreftmedisin. (ekstern lenke)
• Ola Myklebost (2009). “Utforsker kreftsynder” Artikkel om symposiet “Frontiers in Cancer Stem Cell Research: From Basic Science Towards a Cure”. (ekstern lenke)
• Ola Myklebost; Leonardo Andres Zepeda Meza (2009). Skal lage “bok” over alle krefttyper. (ekstern lenke)
• Ola Myklebost (2009). Dreper vi de riktige kreftcellene?. (ekstern lenke)

Populærvitenskapelig artikkel

• Ola Myklebost (2008). Det internasjonale kreftgenomprosjektet. (ekstern lenke)

Rettelse i tidsskrift

• Yuan Yuan; Young Seok Ju; Youngwook Kim et al. (2023). Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x). (ekstern lenke)
• Esther Rheinbay; Morten Muhlig Nielsen; Federico Abascal et al. (2023). Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (Nature, (2020), 578, 7793, (102-111), 10.1038/s41586-020-1965-x). (ekstern lenke)
• Marc Zapatka; Ivan Borozan; Daniel S. Brewer et al. (2023). Author Correction: The landscape of viral associations in human cancers (Nature Genetics, (2020), 52, 3, (320-330), 10.1038/s41588-019-0558-9). (ekstern lenke)
• Claudia Calabrese; Natalie R. Davidson; Deniz Demircioğlu et al. (2023). Author Correction: Genomic basis for RNA alterations in cancer (Nature, (2020), 578, 7793, (129-136), 10.1038/s41586-020-1970-0). (ekstern lenke)
• Sergei Yakneen; Sebastian Martin Waszak; Brice Aminou et al. (2023). Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes (Nature Biotechnology, (2020), 38, 3, (288-292), 10.1038/s41587-019-0360-3). (ekstern lenke)
• Kadir C. Akdemir; Victoria T. Le; Sahaana Chandran et al. (2023). Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (Nature Genetics, (2020), 52, 3, (294-305), 10.1038/s41588-019-0564-y). (ekstern lenke)
• Yuan Yuan; Young Seok Ju; Youngwook Kim et al. (2023). Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x). (ekstern lenke)
• Isidro Cortés-Ciriano; Jake June-Koo Lee; Ruibin Xi et al. (2023). Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing (Nature Genetics, (2020), 52, 3, (331-341), 10.1038/s41588-019-0576-7). (ekstern lenke)
• Moritz Gerstung; Clemency Jolly; Ignaty Leshchiner et al. (2023). Author Correction: The evolutionary history of 2,658 cancers (Nature, (2020), 578, 7793, (122-128), 10.1038/s41586-019-1907-7). (ekstern lenke)
• Yilong Li; Nicola D. Roberts; Jeremiah A. Wala et al. (2023). Author Correction: Patterns of somatic structural variation in human cancer genomes (Nature, (2020), 578, 7793, (112-121), 10.1038/s41586-019-1913-9). (ekstern lenke)
• Ludmil B. Alexandrov; Jaegil Kim; Nicholas J. Haradhvala et al. (2023). Author Correction: The repertoire of mutational signatures in human cancer (Nature, (2020), 578, 7793, (94-101), 10.1038/s41586-020-1943-3). (ekstern lenke)
• Lauri A. Aaltonen; Federico Abascal; Adam Abeshouse et al. (2023). Author Correction: Pan-cancer analysis of whole genomes (Nature, (2020), 578, 7793, (82-93), 10.1038/s41586-020-1969-6). (ekstern lenke)
• Yuan Yuan; Young Seok Ju; Youngwook Kim et al. (2023). Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x). (ekstern lenke)
• Bernardo Rodriguez-Martin; Eva G. Alvarez; Adrian Baez-Ortega et al. (2023). Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (Nature Genetics, (2020), 52, 3, (306-319), 10.1038/s41588-019-0562-0). (ekstern lenke)
• Shimin Shuai; Federico Abascal; Samirkumar B. Amin et al. (2022). Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (Nature Communications, (2020), 11, 1, (734), 10.1038/s41467-019-13929-1). (ekstern lenke)
• Marek Cmero; Ke Yuan; Cheng Soon Ong et al. (2022). Author Correction: Inferring structural variant cancer cell fraction (Nature Communications, (2020), 11, 1, (730), 10.1038/s41467-020-14351-8). (ekstern lenke)
• Yiqun Zhang; Fengju Chen; Nuno A. Fonseca et al. (2022). Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations (Nature Communications, (2020), 11, 1, (736), 10.1038/s41467-019-13885-w). (ekstern lenke)
• Marta Paczkowska; Jonathan Barenboim; Nardnisa Sintupisut et al. (2022). Author Correction: Integrative pathway enrichment analysis of multivariate omics data (Nature Communications, (2020), 11, 1, (735), 10.1038/s41467-019-13983-9). (ekstern lenke)
• Wei Jiao; Gurnit Atwal; Paz Polak et al. (2022). Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns (Nature Communications, (2020), 11, 1, (728), 10.1038/s41467-019-13825-8). (ekstern lenke)
• Matthew A. Reyna; David Haan; Marta Paczkowska et al. (2022). Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes (Nature Communications, (2020), 11, 1, (729), 10.1038/s41467-020-14367-0). (ekstern lenke)
• Yulia Rubanova; Ruian Shi; Caitlin F. Harrigan et al. (2022). Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig (Nature Communications, (2020), 11, 1, (731), 10.1038/s41467-020-14352-7). (ekstern lenke)
• Vinayak Bhandari; Constance H. Li; Robert G. Bristow et al. (2022). Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours (Nature Communications, (2020), 11, 1, (737), 10.1038/s41467-019-14052-x). (ekstern lenke)
• Lina Sieverling; Chen Hong; Sandra D. Koser et al. (2022). Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Nature Communications, (2020), 11, 1, (733), 10.1038/s41467-019-13824-9). (ekstern lenke)

Vitenskapelig artikkel

• David S. Moura; Jesus Lopez-Marti; Hussein Tawbi et al. (2026). Validation of a Seven-Gene Predictive SIGNature for the Efficacy of Immuno-Oncology PD-1 Inhibitors in Patients with Sarcoma. (ekstern lenke)
• Toufik Naolou; Nadine Schadzek; Jan Mathis Hornbostel et al. (2025). Enhanced gelatin methacryloyl nanohydroxyapatite hydrogel for high-fidelity 3D printing of bone tissue engineering scaffolds. (ekstern lenke)
• Anita Sveen; Bjarne Johannessen; Solveig Margrete Knoph Klokkerud et al. (2024). Evolutionary mode and timing of dissemination of high-grade serous carcinomas. (ekstern lenke)
• Parmida Ranji; Emma Jonasson; Lisa Andersson et al. (2024). Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development. (ekstern lenke)
• Yang Zhou; Partho Sarothi Ray; Jianguo Zhu et al. (2024). Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma. (ekstern lenke)
• Baoyan Bai; Jillian Frances Wise; Daniel Vodak et al. (2024). Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma. (ekstern lenke)
• Mandy L. Ballinger; Swetansu Pattnaik; Piyushkumar A. Mundra et al. (2023). Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (ekstern lenke)
• Irantzu Anzar Martinez de Lagran; Brandon Malone; Pubudu Saneth Samarakoon et al. (2023). The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition. (ekstern lenke)
• Heidi Maria Namløs; Ksenia Khelik; Sigve Nakken et al. (2023). Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential. (ekstern lenke)
• Heidi Maria Namløs; Magne Nordang Skårn; Deeqa Ahmed Mohamed Ali et al. (2022). miR-486-5p expression is regulated by DNA methylation in osteosarcoma. (ekstern lenke)
• Kristine Misund; Davine Hofste op Bruinink; Eivind Coward et al. (2022). Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. (ekstern lenke)
• Andreas Venizelos; Christina Engebrethsen; Wei Deng et al. (2022). Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy. (ekstern lenke)
• Anita Sveen; Bjarne Johannessen; Ina Andrassy Eilertsen et al. (2021). The expressed mutational landscape of microsatellite stable colorectal cancers. (ekstern lenke)
• Iwona Grad; Robert Hanes; Maria del Pilar Ayuda-Duran et al. (2021). Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening. (ekstern lenke)
• Tatiana Georgiesh; Heidi Maria Namløs; Nitin Sharma et al. (2021). Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour. (ekstern lenke)
• Marianne Stabell; Thomas Sæther; Åsmund Røhr Kjendseth et al. (2021). Methylation-dependent SUMOylation of the architectural transcription factor HMGA2. (ekstern lenke)
• Peter Peneder; Adrian M. Stütz; Didier Surdez et al. (2021). Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden. (ekstern lenke)
• Sigve Nakken; Vladislav Saveliev; Oliver Hofmann et al. (2021). Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer. (ekstern lenke)
• Jillian Wise; Sigve Nakken; Chloe Beate Steen et al. (2020). Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series. (ekstern lenke)
• Ansastassia Serguienko; Peder Rustøen Braadland; Leonardo A. Meza-Zepeda et al. (2020). Accurate 3-gene-signature for early diagnosis of liposarcoma progression. (ekstern lenke)
• Constance H. Li; Stephenie D. Prokopec; Ren X. Sun et al. (2020). Sex differences in oncogenic mutational processes. (ekstern lenke)
• Marc Zapatka; Ivan Borozan; Daniel S. Brewer et al. (2020). The landscape of viral associations in human cancers. (ekstern lenke)
• Kadir C. Akdemir; Victoria T. Le; Sahaana Chandran et al. (2020). Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer. (ekstern lenke)
• Yuan Yuan; Young Seok Ju; Youngwook Kim et al. (2020). Comprehensive molecular characterization of mitochondrial genomes in human cancers. (ekstern lenke)
• Bernardo Rodriguez-Martin; Eva G. Alvarez; Adrian Baez-Ortega et al. (2020). Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. (ekstern lenke)
• Matthew H. Bailey; William U. Meyerson; L. Jonathan Dursi et al. (2020). Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. (ekstern lenke)
• Isidro Cortés-Ciriano; Jake June-Koo Lee; Ruibin Xi et al. (2020). Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. (ekstern lenke)
• of Whole Genomes Consortium ICGC/TCGA Pan-Cancer Analysis; Peter J. Campbell; Gad Getz et al. (2020). Pan-cancer analysis of whole genomes. (ekstern lenke)
• Yulia Rubanova; Ruian Shi; Caitlin F. Harrigan et al. (2020). Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. (ekstern lenke)
• Marek Cmero; Ke Yuan; Cheng Soon Ong et al. (2020). Inferring structural variant cancer cell fraction. (ekstern lenke)
• Marek Cmero; Ke Yuan; Cheng Soon Ong et al. (2020). Inferring structural variant cancer cell fraction. (ekstern lenke)
• Wei Jiao; Gurnit Atwal; Paz Polak et al. (2020). A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. (ekstern lenke)
• Lina Sieverling; Chen Hong; Sandra D. Koser et al. (2020). Genomic footprints of activated telomere maintenance mechanisms in cancer. (ekstern lenke)
• Jessica Dörnen; Ola Myklebost; Thomas Dittmar (2020). Cell Fusion of Mesenchymal Stem/Stromal Cells and Breast Cancer Cells Leads to the Formation of Hybrid Cells Exhibiting Diverse and Individual (Stem Cell) Characteristics. (ekstern lenke)
• Vinayak Bhandari; Constance H. Li; Robert G. Bristow et al. (2020). Divergent mutational processes distinguish hypoxic and normoxic tumours. (ekstern lenke)
• Yiqun Zhang; Fengju Chen; Nuno A. Fonseca et al. (2020). High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. (ekstern lenke)
• Robert Hanes; Else Munthe; Iwona Grad et al. (2019). Preclinical Evaluation of the Pan-FGFR Inhibitor LY2874455 in FRS2-Amplified Liposarcoma. (ekstern lenke)
• Daniel Vodak; Susanne Lorenz; Sigve Nakken et al. (2018). Sample-Index Misassignment Impacts Tumour Exome Sequencing. (ekstern lenke)
• Stine Henrichson Kresse; Heidi Maria Namløs; Susanne Lorenz et al. (2018). Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples. (ekstern lenke)
• Sarina Gouravan; Leonardo Zepeda Meza; Ola Myklebost et al. (2018). Preclinical evaluation of vemurafenib as therapy for BRAFV600E mutated sarcomas. (ekstern lenke)
• Einar Elvbakken Birkeland; Shan Zhang; Deepak Poduval et al. (2018). Patterns of genomic evolution in advanced melanoma. (ekstern lenke)
• Heidi Maria Namløs; Kjetil Boye Pedersen; Skyler J. Mishkin et al. (2018). Noninvasive Detection of ctDNA Reveals Intratumor Heterogeneity and Is Associated with Tumor Burden in Gastrointestinal Stromal Tumor. (ekstern lenke)
• Sigve Nakken; Ghislain Fournous; Daniel Vodak et al. (2018). Personal Cancer Genome Reporter: Variant interpretation report for precision oncology. (ekstern lenke)
• Marthe Løvf; Sen Zhao; Ulrika Axcrona et al. (2018). Multifocal primary prostate cancer exhibits high degree of genomic heterogeneity. (ekstern lenke)
• Anastassia Serguienko; Mengyu Wang; Ola Myklebost (2018). Real-time vital mineralization detection and quantification during in vitro osteoblast differentiation. (ekstern lenke)
• Marie Elise Engkvist; Eva Wessel Stratford; Susanne Lorenz et al. (2017). Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b. (ekstern lenke)
• Kaja Christine Graue Berg; Peter Andreas Wold Eide; Ina Andrassy Eilertsen et al. (2017). Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies. (ekstern lenke)
• Even Holth Rustad; Eivind Coward; Emilie R Skytøen et al. (2017). Monitoring multiple myeloma by quantification of recurrent mutations in serum. (ekstern lenke)
• Sam Behjati; Patrick S. Tarpey; Kerstin Haase et al. (2017). Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma. (ekstern lenke)
• Heidi Maria Namløs; Olga Zaikova; Bodil Bjerkehagen et al. (2017). Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report. (ekstern lenke)
• Anita Sveen; Bjarne Johannessen; Torstein Tengs et al. (2017). Multilevel genomics of colorectal cancers with microsatellite instability – clinical impact of JAK1 mutations and consensus molecular subtype 1. (ekstern lenke)
• Åslaug Helland; Odd Terje Brustugun; Sigve Nakken et al. (2017). High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival. (ekstern lenke)
• Anastassia Serguienko; Robert Hanes; Iwona Grad et al. (2017). PP2A regulatory subunit b55γ is a gatekeeper of osteoblast maturation and lineage maintenance. (ekstern lenke)
• Tale Barøy; Chandra Sekhar Reddy Chilamakuri; Susanne Lorenz et al. (2016). Genome analysis of osteosarcoma progression samples identifies FGFR1 overexpression as a potential treatment target and CHM as a candidate tumor suppressor gene. (ekstern lenke)
• Vandana Sandhu; David C. Wedge; Inger Marie Bowitz Lothe et al. (2016). The genomic landscape of pancreatic and periampullary adenocarcinoma. (ekstern lenke)
• Robert Hanes; Iwona Grad; Susanne Lorenz et al. (2016). Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma. (ekstern lenke)
• Susanne Lorenz; Tale Barøy; Jinchang Sun et al. (2016). Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations. (ekstern lenke)
• Ann Rita Halvorsen; Laxmi Silwal-Pandit; Leonardo Zepeda Meza et al. (2016). TP53 mutation spectrum in smokers and never smoking lung cancer patients. (ekstern lenke)
• Mandy L. Ballinger; David L. Goode; Isabelle Ray-Coquard et al. (2016). Monogenic and polygenic determinants of sarcoma risk: an international genetic study. (ekstern lenke)
• Elin Hallan Naderi; Seham Skah; Hege Katrin Ugland et al. (2015). Bone marrow stroma-derived PGE<sub>2</sub> protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death. (ekstern lenke)
• Anastassia Serguienko; Iwona Grad; Anna Wennerstrøm et al. (2015). Metabolic reprogramming of metastatic breast cancer and melanoma by Let-7a microRNA. (ekstern lenke)
• S Safavi; S Järnum; C Vannas et al. (2015). HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo. (ekstern lenke)
• Ola Myklebost (2015). Norwegian Cancer Genomics Consortium: A platform for research on personalized cancer medicine in a public health system. (ekstern lenke)
• Even Holth Rustad; Hong Yan Dai; Håkon Hov et al. (2015). BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. (ekstern lenke)
• Deepika Kanojia; Yasunobu Nagata; Manoj Garg et al. (2015). Genomic landscape of liposarcoma. (ekstern lenke)
• Y.S Ju; J.M.C Tubio; W Mifsud et al. (2015). Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. (ekstern lenke)
• Magne Nordang Skårn; Paul Noordhuis; Mengyu Wang et al. (2014). Generation and characterization of an immortalized human mesenchymal stromal cell line. (ekstern lenke)
• Anna Wennerstrøm; Inger Marie Bowitz Lothe; Vandana Sandhu et al. (2014). Generation and Characterisation of Novel Pancreatic Adenocarcinoma Xenograft Models and Corresponding Primary Cell Lines. (ekstern lenke)
• Jakob K. Anninga; Anne-Marie Cleton-Jansen; Bass Hassan et al. (2014). Workshop Report on the 2nd Joint ENCCA/EuroSARC European Bone Sarcoma Network Meeting: Integration of Clinical Trials with Tumour Biology.. (ekstern lenke)
• JMC Tubio; Y Li; YS Ju et al. (2014). Extensive transduction of non-reptitive DNA mediated by L1 retrotransposition in cancer genomes. (ekstern lenke)
• Eva Wessel Stratford; Jeanette L. Daffinrud; Else Munthe et al. (2014). The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines. (ekstern lenke)
• Anne-Mari Håkelien; Jan Christian Bryne; Kristine Gjul Harstad et al. (2014). The regulatory landscape of osteogenic differentiation. (ekstern lenke)
• Chandra Sekhar Reddy Chilamakuri; Susanne Lorenz; Mohammed-Amin Madoui et al. (2014). Performance comparison of four exome capture systems for deep sequencing. (ekstern lenke)
• Tale Barøy; Stine Henrichson Kresse; Magne Nordang Skårn et al. (2014). Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model. (ekstern lenke)
• Eva Wessel Stratford; Ola Myklebost (2014). TRAP1 is a novel interaction partner of PML, localised with PML in nuclear bodies and relocating with PML to the cytoplasm following stress. (ekstern lenke)
• Dale W. Garsed; Owen J. Marshall; Vincent D.A. Corbin et al. (2014). The Architecture and Evolution of Cancer Neochromosomes. (ekstern lenke)
• Laurence Bianchini; Loic Birtwisle; Esma Saada et al. (2013). Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas. (ekstern lenke)
• Marieke L. Kuijjer; Elisabeth FP Peterse; BEWM van den Akker et al. (2013). IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma. (ekstern lenke)
• Eva Wessel Stratford; Monica Bostad; Castro Russell et al. (2013). Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity. (ekstern lenke)
• Cecilie Sandberg; Gabriel Altschuler; Jieun Jeong et al. (2013). Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome. (ekstern lenke)
• Magne Skårn; Tale Barøy; Eva Wessel Stratford et al. (2013). Epigenetic Regulation and Functional Characterization of MicroRNA-142 in Mesenchymal Cells. (ekstern lenke)
• Hege Oma Ohnstad; Russell Castro; Jinchang Sun et al. (2013). Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma. (ekstern lenke)
• Joyce Doorn; Hugo A.M. Fernandes; Bach Q. Le et al. (2013). A small molecule approach to engineering vascularized tissue. (ekstern lenke)
• Silje Anett Ugland Lauvrak; Else Munthe; Stine Henrichson Kresse et al. (2013). Functional characterization of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes. (ekstern lenke)
• Torfinn Nome; Gard O Sundby Thomassen; Jarle Bruun et al. (2013). Common fusion transcripts identified in colorectal cancer cell lines by high throughput RNA sequencing. (ekstern lenke)
• Sam Behjati; Patrick S. Tarpey; Nadège Presneau et al. (2013). Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone. (ekstern lenke)
• Stine Henrichson Kresse; Leonardo Zepeda Meza; Isidro Machado et al. (2012). Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations. (ekstern lenke)
• Stine Henrichson Kresse; Halfdan Rydbeck; Magne Skårn et al. (2012). Integrative Analysis Reveals Relationships of Genetic and Epigenetic Alterations in Osteosarcoma. (ekstern lenke)
• Heidi Maria Namløs; Stine Henrichson Kresse; Christoph Rainer Muller et al. (2012). Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern. (ekstern lenke)
• Marieke L. Kuijjer; Halfdan Rydbeck; Stine Henrichson Kresse et al. (2012). Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data. (ekstern lenke)
• Magne Skårn; Heidi Maria Namløs; Paul Noordhuis et al. (2012). Adipocyte Differentiation of Human Bone Marrow-Derived Stromal Cells Is Modulated by MicroRNA-155, MicroRNA-221, and MicroRNA-222. (ekstern lenke)
• Heidi Maria Namløs; Leonardo Andrés Meza-Zepeda; Tale Barøy et al. (2012). Modulation of the Osteosarcoma Expression Phenotype by MicroRNAs. (ekstern lenke)
• Eva Wessel Stratford; Russell Castro; Jeanette L. Daffinrud et al. (2012). Characterization of liposarcoma cell lines for preclinical and biological studies. (ekstern lenke)
• Hege Oma Ohnstad; Erik Braarød Paulsen; Paul Noordhuis et al. (2011). MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines. (ekstern lenke)
• Geir Olav Hjortland; Leonardo Zepeda Meza; Klaus Beiske et al. (2011). Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma. (ekstern lenke)
• Marieke L. Kuijjer; Heidi Maria Namløs; Esther I. Hauben et al. (2011). mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts. (ekstern lenke)
• Emilie P. Buddingh; Marieke L. Kuijjer; Ronald A.J. Duim et al. (2011). Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents. (ekstern lenke)
• Magne Skårn; Heidi Maria Namløs; Paul Noordhuis et al. (2011). Adipocyte Differentiation of Immortalized Human Bone Marrow-Derived Stromal Cells is Modulated by microRNA-155, microRNA-221 and microRNA-222. (ekstern lenke)
• Eva Wessel Stratford; R Castro; Anna Berit Wennerström et al. (2011). Combined ALDH and CD133 expression defines a stem-like cancer cell population in liposarcoma xenograft. (ekstern lenke)
• Stine Henrichson Kresse; Leonardo Zepeda Meza; Isidro Machado et al. (2011). Genomic validation of preclinical xenograft models of human sarcoma reveals recurrent loss of aberrations. (ekstern lenke)
• EP Buddingh; ML Kuijjer; RL Duim et al. (2011). Metastasis suppression by tumor-infiltrating macrophages in high-grade osteosarcoma. (ekstern lenke)
• Ellen Tenstad; Anna Tourovskaia; Albert Folch et al. (2010). Extensive adipogenic and osteogenic differentiation of patterned human mesenchymal stem cells in a microfluidic device. (ekstern lenke)
• Marianne Brodtkorb Eide; Knut Liestøl; Ole Christian Lingjærde et al. (2010). Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones. (ekstern lenke)
• E Mayordomo; I Machado; F Giner et al. (2010). A Tissue Microarray Study of Osteosarcoma: Histopathologic and Immunohistochemical Validation of Xenotransplanted Tumors as Preclinical Models. (ekstern lenke)
• Stine Henrichson Kresse; K Szuhai; Ana Heslanyeth Barragan Polania et al. (2010). Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours. (ekstern lenke)
• Stine Henrichson Kresse; Hege Oma Ohnstad; Bodil Bjerkehagen et al. (2010). DNA Copy Number Changes in Human Malignant Fibrous Histiocytomas by Array Comparative Genomic Hybridisation. (ekstern lenke)
• Christoph Rainer Muller; Heidi Maria Namløs; Johan Bjerner et al. (2010). Characterization of Treatment Response to Recombinant Interferon-α2b in Osteosarcoma Xenografts. (ekstern lenke)
• L Ottaviano; K-L Schaefer; M Gajewski et al. (2010). Molecular Characterization of Commonly Used Cell Lines for Bone Tumor Research: A Trans-European EuroBoNet Effort. (ekstern lenke)
• Jørn Henriksen; Marianne Stabell; Leonardo Zepeda Meza et al. (2010). Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells. (ekstern lenke)
• Gustav Lehne; Unn-Hilde Grasmo-Wendler; Jeanne-Marie Berner et al. (2009). Upregulation of stem cell genes in multidrug resistant K562 leukemia cells. (ekstern lenke)
• L Ottaviano; K-L Schaefer; M Gajewski et al. (2009). Molecular characterization of commonly used cell lines for bone tumor research. A trans-European EuroBoNet effort. (ekstern lenke)
• Stine Henrichson Kresse; HO Ohnstad; Erik Braarød Paulsen et al. (2009). LSAMP, a Novel Candidate Tumor Suppressor Gene in Human Osteosarcomas, Identified by Array Comparative Genomic Hybridization. (ekstern lenke)
• Stine Henrichson Kresse; Magne Skårn; Hege Oma Ohnstad et al. (2008). DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH. (ekstern lenke)
• Eric Roman; Leonardo A. Meza-Zepeda; Stine H. Kresse et al. (2008). Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization. (ekstern lenke)
• Zepeda Leonardo Meza; Agate Noer; John Arne Dahl et al. (2008). High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence. (ekstern lenke)
• E Roman; Leonardo Andres Zepeda Meza; Stine Henrichson Kresse et al. (2008). Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization. (ekstern lenke)
• H Lyng; M Lando; RS Brovig et al. (2008). GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data. (ekstern lenke)
• Kristine Kleivi; Guro E Lind; Chieu B Diep et al. (2007). Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses. (ekstern lenke)
• CR Muller; EB Paulsen; P Noordhuis et al. (2007). Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A. (ekstern lenke)
• P Francis; HM Namlos; C Muller et al. (2007). Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential. (ekstern lenke)
• Jeanne-Marie Berner; Christoph Rainer Muller; Marit Holden et al. (2006). Sampling effects on gene expression data from a human tumour xenograft. (ekstern lenke)

Vitenskapelig litteraturgjennomgang

• Leo Kager; Jeremy Whelan; U Dirksen et al. (2016). The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report. (ekstern lenke)
• Ola Myklebost (2015). Personalized cancer therapy for soft tissue sarcomas: progress and pitfalls. (ekstern lenke)
• José M.C. Tubio; Yilong Li; Young Seok Ju et al. (2014). Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. (ekstern lenke)
• DM Thomas; M Wilhelm; Anne-Marie Cleton-Jansen et al. (2012). Workshop report on the European Bone Sarcoma Networking Meeting: integration of clinical trials with tumor biology. (ekstern lenke)

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Se publikasjonsliste på myklebost.uib.no

Main projects:

NoSarC, characterization of a national 3-year cohort of sarcoma patients and their samples, including establishment and characterization of disease models.

KidImmune, a study of autoimmunity in pediatric cancer patients.