Trond Bruun
Stilling
førsteamanuensis, UiB. Seksjonsoverlege, Haukeland universitetssykehus
Tilhørighet
Forskergrupper
Forskning
Trond Bruun er seksjonsoverlege ved Infeksjonsseksjonen , Medisinsk klinikk, Haukeland universitetssykehus og 1. amanuensis II ved Klinisk institutt 2, UiB. Viktigste forskningfelt er innen alvorlige hud- og bløtvevsinfeksjoner, spesielt erysipelas, cellulitt og nekrotiserende fasciitt forårsaket av Streptococcus pyogenes og Streptococcus dysgalactiae. Forskningen fokuserer først og fremst på klinisk epidemiologi, kliniske trekk og behandling sett i relasjon til verten og bakterienes egenskaper. For tiden deltar Bruun og streptokokkforskningsgruppen ved Universitetet i Bergen og Haukeland universitetssykehus i PERMIT- og PERAID-prosjektene (https://permedinfect.com/) finansiert av Nordforsk og EU. Disse prosjektene har som mål å fremme forskning på persontilpasset medisin (PM) ved alvorlige infeksjonssykdommer, spesielt livstruende nekrotiserende bløtvevsinfeksjoner (NSTI) og sepsis.
Undervisning
Trond Bruun underviser medisinstudenter i infeksjonssykdommer i flere semestre (MED6, MED8, MED11 og MED12).
Publikasjoner
Vitenskapelig artikkel
- Ole Hyldegaard; Michael Nekludov; Per Arnell et al. (2025). Use of Hyperbaric Oxygen in Patients with Necrotizing Soft Tissue Infections: A Scandinavian Multicenter, Prospective, Observational Cohort. (ekstern lenke)
- Martin Bruun Madsen; Steinar Skrede; Anders Perner et al. (2019). Patient's characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study. (ekstern lenke)
- Trond Bruun; Eivind Rath; Martin Bruun Madsen et al. (2020). Risk factors and Predictors of Mortality in Streptococcal Necrotizing Soft-Tissue Infections: A Multicenter Prospective Study. (ekstern lenke)
- Trond Bruun; Oddvar Oppegaard; Karl Ove Hufthammer et al. (2016). Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors. (ekstern lenke)
- Trond Bruun; Bård Reiakvam Kittang; Bram Johan de Hoog et al. (2013). Necrotizing soft tissue infections caused by Streptococcus pyogenes and Streptococcus dysgalactiae subsp equisimilis of groups C and G in western Norway. (ekstern lenke)
- Robert Thänert; Andreas Itzek; Jörn Hoßmann et al. (2019). Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections. (ekstern lenke)
- Eivind Rath; Steinar Skrede; Haima Mylvaganam et al. (2018). Aetiology and clinical features of facial cellulitis: a prospective study. (ekstern lenke)
- Anshu Babbar; Trond Bruun; Ole Hyldegaard et al. (2018). Pivotal role of prexexisting pathogen-spesific antibodies in the development of necrotizing soft-tissue infections.. (ekstern lenke)
- Ingunn Gundersen; Trond Bruun; Stian Kreken Almeland et al. (2024). Necrotizing soft tissue infections. (ekstern lenke)
- Anshu Babbar; Trond Bruun; Ole Hyldegaard et al. (2018). Pivotal Role of Preexisting Pathogen-Specific Antibodies in the Development of Necrotizing Soft-Tissue Infections. (ekstern lenke)
- Laura M. Palma Medina; Eivind Rath; Sanjeevan Jahagirdar et al. (2021). Discriminatory plasma biomarkers for specific endotypes of necrotizing soft tissue infections.. (ekstern lenke)
- Trond Bruun; Bård Reiakvam Kittang; Haima Mylvaganam et al. (2010). Clinical, microbiological and molecular characteristics of six cases of group A streptococcal meningitis in western Norway. (ekstern lenke)
- Ingunn Margareetta Gundersen; Ellen Berget; Hans Kristian Haugland et al. (2022). Clinical Characteristics and Histopathology in Suspected Necrotizing Soft Tissue Infections. (ekstern lenke)
- Nikolai Siemens; Bård Reiakvam Kittang; Bhavya Chakrakodi et al. (2015). Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections. (ekstern lenke)
- Bjørn Blomberg; Trond Bruun; Stina Jordal et al. (2024). Ein mann i 60-åra med livstrugande febersjukdom etter utanlandsreise. (ekstern lenke)
- Olav Lutro; Synnøve Mo; Marianne Bollestad et al. (2024). How good are surgeons at disclosing periprosthetic joint infection at the time of revision, based on pre- and intra-operative assessment? A study on 16,922 primary total hip arthroplasties reported to the Norwegian Arthroplasty Register. (ekstern lenke)
- Olav Lutro; Marianne Bollestad; Tesfaye Hordofa Leta et al. (2025). How many doses and what type of antibiotic should be used as systemic antibiotic prophylaxis in primary hip and knee arthroplasty? A register-based study on 301,204 primary total and hemi-hip and total knee arthroplasties in Norway 2005–2023. (ekstern lenke)
- Sanjeevan Jahagirdar; Lorna Morris; Nirupama Benis et al. (2022). Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections. (ekstern lenke)
- Trond Bruun; Oddvar Oppegaard; Bård Reiakvam Kittang et al. (2016). Etiology of cellulitis and clinical prediction of streptococcal disease: A prospective study. (ekstern lenke)
- Eivind Rath; Steinar Skrede; Oddvar Oppegaard et al. (2020). Non-purulent skin and soft tissue infections: predictive power of a severity score and the appropriateness of treatment in a prospective cohort. (ekstern lenke)
- Martin Bruun Madsen; Steinar Skrede; Trond Bruun et al. (2018). Necrotizing soft tissue infections: a multicentre, prospective observational study (INFECT): protocol and statistical analysis plan. (ekstern lenke)
- Eivind Rath; Laura M. Palma Medina; Sanjeevan Jahagirdar et al. (2023). Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study. (ekstern lenke)
- Bård Reiakvam Kittang; Trond Bruun; Nina Langeland et al. (2011). Invasive group A, C and G streptococcal disease in western Norway: virulence gene profiles, clinical features and outcomes. (ekstern lenke)
- Marco Bo Hansen; Lars Simon Rasmussen; Mattias Svensson et al. (2017). Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: A multicentre, prospective study. (ekstern lenke)