KG Jebsen Senter for Diabetesforskning

Diabetesforskar i verdensklasse

Toppforskprogrammet ved UiB

 

Vitenskapelig artikkel

• Liisa Hakaste; Mette K. Andersen; Lars Ängquist et al. (2026). Metabolic Trajectories Before Diabetes Diagnosis Across Subgroups: A Pooled Analysis of Prospective European Cohort Studies. (ekstern lenke)
• Vera Vik Bjarkø; Brooke N. Wolford; Eirin Beate Haug et al. (2026). Temporal changes and genetic susceptibility to type 2 diabetes (1984-2019; HUNT): a longitudinal, population-based study. (ekstern lenke)
• Roelof A.J. Smit; Kaitlin H. Wade; Qin Hui et al. (2025). Polygenic prediction of body mass index and obesity through the life course and across ancestries. (ekstern lenke)
• Türküler Özgümüs; Oksana Sulaieva; Most Champa Begum et al. (2025). DNA repair and inflammatory response genes play a central role in protecting patients with long-standing type 1 diabetes from vascular complications. (ekstern lenke)
• Vasiliki Lagou; Reedik Mägi; Jouke- Jan Hottenga et al. (2021). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. (ekstern lenke)
• E Zeggini; LJ Scott; R Saxena et al. (2008). Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. (ekstern lenke)
• Ken Suzuki; Konstantinos Hatzikotoulas; Lorraine Southam et al. (2024). Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. (ekstern lenke)
• AP Morris; BF Voight; TM Teslovich et al. (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. (ekstern lenke)
• Dmitry Shungin; Thomas W. Winkler; Damien C. Croteau-Chonka et al. (2015). New genetic loci link adipose and insulin biology to body fat distribution. (ekstern lenke)
• Mikael Akerlund; Georgios Baskozos; Wenqianglong Li et al. (2024). Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort. (ekstern lenke)
• Christian Fuchsberger; Jason Flannick; Tanya M. Teslovich et al. (2016). The genetic architecture of type 2 diabetes. (ekstern lenke)
• Andrew R. Wood; Tonu Esko; Jian Yang et al. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. (ekstern lenke)
• Loïc Yengo; Sailaja Vedantam; Eirini Marouli et al. (2022). A saturated map of common genetic variants associated with human height. (ekstern lenke)
• Jens Kristoffer Hertel; Stefan Johansson; H Ræder et al. (2008). Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study). (ekstern lenke)
• Magdalena Keindl; Richard Allan Davies; Brith Bergum et al. (2022). Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren’s syndrome. (ekstern lenke)
• Jason Flannick; Nicola L. Beer; Alexander G. Bick et al. (2013). Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. (ekstern lenke)
• Anubha Mahajan; Cassandra N. Spracklen; Weihua Zhang et al. (2022). Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. (ekstern lenke)
• Olena Fedotkina; Ruchi Jain; Rashmi B. Prasad et al. (2022). Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes. (ekstern lenke)
• Janina S. Ried; Janina M. Jeff; Audrey Y. Chu et al. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. (ekstern lenke)
• Manuel Carrasco Fernandez; Chencheng Wang; Anne Mette Søviknes et al. (2022). Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. (ekstern lenke)
• Olena Fedotkina; Andrea O.Y. Luk; Ruchi Jain et al. (2021). Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes. (ekstern lenke)
• Jason Flannick; Christian Fuchsberger; Anubha Mahajan et al. (2017). Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. (ekstern lenke)
• Roderick C. Slieker; Louise A. Donnelly; Elina Akalestou et al. (2023). Identification of biomarkers for glycaemic deterioration in type 2 diabetes. (ekstern lenke)
• Anubha Mahajan; Min Jin Go; Weihua Zhang et al. (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. (ekstern lenke)
• Ji Chen; Cassandra N. Spracklen; Gaëlle Marenne et al. (2021). The trans-ancestral genomic architecture of glycemic traits. (ekstern lenke)
• Magdalena Keindl; Olena Fedotkina; Elsa du Plessis et al. (2020). Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms. (ekstern lenke)
• Shweta Ramdas; Jonathan Judd; Sarah E. Graham et al. (2022). A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. (ekstern lenke)
• Natalie R. van Zuydam; Emma Ahlqvist; Niina Sandholm et al. (2018). A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes. (ekstern lenke)
• George Hindy; Peter Dornbos; Mark D. Chaffin et al. (2022). Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes. (ekstern lenke)
• Eleanor Wheeler; Aaron Leong; Ching-Ti Liu et al. (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. (ekstern lenke)
• Jens Kristoffer Hertel; Stefan Johansson; Emily Sonestedt et al. (2011). FTO, type 2 diabetes, and weight gain throughout adult life A meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies. (ekstern lenke)
• Olena Fedotkina; Oksana Sulaieva; Türküler Özgümüs et al. (2021). Novel Reclassification of Adult Diabetes Is Useful to Distinguish Stages of β-Cell Function Linked to the Risk of Vascular Complications: The DOLCE Study From Northern Ukraine. (ekstern lenke)
• Roderick C. Slieker; Louise A. Donnelly; Hugo Fitipaldi et al. (2021). Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study. (ekstern lenke)
• Stavroula Kanoni; Sarah E. Graham; Yuxuan Wang et al. (2022). Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. (ekstern lenke)
• Adam E. Locke; Bratati Kahali; Sonja I. Berndt et al. (2015). Genetic studies of body mass index yield new insights for obesity biology. (ekstern lenke)
• Ruchi Jain; Türküler Özgümüs; Troels Mygind Jensen et al. (2020). Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes. (ekstern lenke)
• Julia K. Goodrich; Moriel Singer-Berk; Rachel Son et al. (2021). Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. (ekstern lenke)
• Vera Vik Bjarkø; Eirin Beate Haug; Arnulf Langhammer et al. (2024). Clinical utility of novel diabetes subgroups in predicting vascular complications and mortality: up to 25 years of follow-up of the HUNT Study. (ekstern lenke)
• Roderick C. Slieker; Louise A. Donnelly; Hugo Fitipaldi et al. (2021). Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study. (ekstern lenke)
• Samuela Pollack; Robert P. Igo; Richard A. Jensen et al. (2019). Multiethnic genome-wide association study of diabetic retinopathy using liability threshold modeling of duration of diabetes and glycemic control. (ekstern lenke)
• Kasper Olesen; Troels Mygind Jensen; Lars Jorge Diaz et al. (2017). Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes - The PROLONG-Steno study. (ekstern lenke)
• BF Voight; LJ Scott; V Steinthorsdottir et al. (2010). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. (ekstern lenke)
• Türküler Özgümüs; Oksana Sulaieva; Leon E. Jessen et al. (2021). Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study. (ekstern lenke)
• Valeriya Lyssenko (2020). Koble. (ekstern lenke)
• Türküler Özgümüs; Oksana Sulaieva; Ruchi Jain et al. (2021). Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells. (ekstern lenke)
• Anubha Mahajan; Daniel Taliun; Matthias Thurner et al. (2018). Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. (ekstern lenke)
• Jason Flannick; Josep M. Mercader; Christian Fuchsberger et al. (2019). Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. (ekstern lenke)
• Sarah E. Graham; Shoa L. Clarke; Kuan-Han H. Wu et al. (2021). The power of genetic diversity in genome-wide association studies of lipids. (ekstern lenke)

Rettelse i tidsskrift

• Sarah E. Graham; Shoa L. Clarke; Kuan-Han H. Wu et al. (2023). Author Correction: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3). (ekstern lenke)
• Vasiliki Lagou; Reedik Mägi; Jouke- Jan Hottenga et al. (2021). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9). (ekstern lenke)

Vitenskapelig litteraturgjennomgang

• G Salanti; L Southam; D Altshuler et al. (2009). Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations. (ekstern lenke)
• Valeriya Lyssenko; Allan Vaag (2023). Genetics of diabetes-associated microvascular complications. (ekstern lenke)

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