Aurora Martinez is the leader of the research group Biorecognition that studies the relation between biomolecular structure and function to understand and develop new therapeutic options for genetic diseases, notably neurometabolic disorders such as phenylketonuria (PKU) and defects in dopamine synthesis.

Aurora is also a partner in the KG Jebsen Centre for neuropsychiatric disorders. In addition, she is also a partner in the project 'Molecular control of Arc protein: Decoding a master regulator of synaptic plasticity and cognition', coordinated by Clive Bramham, which received support from the Toppforsk Program (NFR).

MEDOD1

MEDOD2

2007

• Angel L. Pey; Francois Stricher; Luis Serrano et al. (2007). Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases. (external link)

2004

• Frederico F. Miranda; Matthias Thorolfsson; Knut Teigen et al. (2004). Structural and stability effects of phosphorylation � Localized structural changes in phenylalanine hydroxylase. (external link)

1997

• H Erlandsen; Aurora Martinez; Per Knappskog et al. (1997). Crystallization and preliminary diffraction analysis of a truncated homodimer of human phenylalanine hydroxylase. (external link)

2010

• Sara Elaine Olsson; Aurora Martinez; Knut Teigen et al. (2010). The aromatic amino acid hydroxylase mechanism: a perspective from computational chemistry. (external link)

2015

• Sara Wettstein; Jarl Underhaug; Belen Perez et al. (2015). Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria. (external link)

2017

• Nenad Blau; Aurora Martinez; Georg F. Hoffmann et al. (2017). DNAJC12 deficiency: A new strategy in the diagnosis of hyperphenylalaninemias. (external link)

2009

• Helene Bustad Johannessen; Øyvind Halskau jr; Aurora Martinez (2009). Exploring the Membrane Binding Capacity and Mechanism of 14-3-3γ. (external link)

1996

• W. Meyer; V. Shünemann; H. Winkler et al. (1996). Characterization of the iron environment in human tyrosine hydroxylase, using M#"ossbauer-, EPR-, and EXAFS-spectroscopy. (external link)
• Aurora Martinez; Jan Haavik; Torgeir Flatmark (1996). Conformational properties and stability of tyrosine hydroxylase studied by infrared spectroscopy. Effect of iron/catecholamine binding and phosphorylation. (external link)

2002

• Frederiko Miranda; Knut Teigen; Matthias Thorolfsson et al. (2002). Phosphorylation and mutations of Ser16 in human phenylalanine hydroxylase. Kinetic and structural effects. (external link)

See a complete overview of publications in Cristin.