Research groups
Research
Aurora Martinez is the leader of the research group Biorecognition that studies the relation between biomolecular structure and function to understand and develop new therapeutic options for genetic diseases, notably neurometabolic disorders such as phenylketonuria (PKU) and defects in dopamine synthesis.
Aurora is also a partner in the KG Jebsen Centre for neuropsychiatric disorders. In addition, she is also a partner in the project 'Molecular control of Arc protein: Decoding a master regulator of synaptic plasticity and cognition', coordinated by Clive Bramham, which received support from the Toppforsk Program (NFR).
Teaching
MEDOD1
MEDOD2
Publications
2025
- Ramosaj, Adhuresa; Borsuk, Mariia; Underhaug, Jarl et al. (2025). Novel Treatment Strategy for Patients With Urea Cycle Disorders: Pharmacological Chaperones Enhance Enzyme Stability and Activity in Patient‐Derived Liver Disease Models. (external link)
- Tai, Mary Dayne Sia; Ochoa, Lissette; Flydal, Marte Innselset et al. (2025). Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12. (external link)
2024
- Ruisch, I. Hyun; Widomska, Joanna; Witte, Ward De et al. (2024). Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases. (external link)
- Himmelreich, Nastassja; Ramón-Maiques, Santiago; Navarrete, Rosa et al. (2024). Significance of utilizing in silico structural analysis and phenotypic data to characterize phenylalanine hydroxylase variants: A PAH landscape. (external link)
- C, Kunwar Jung K; Tristán-Noguero, Alba; Altankhuyag, Altanchimeg et al. (2024). Tetrahydrobiopterin (BH<inf>4</inf>) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-in mouse model. (external link)
- Martin-Malpartida, Pau; Torner, Carles; Martinez, Aurora et al. (2024). TPPU_DSF: A Web Application to Calculate Thermodynamic Parameters Using DSF Data. (external link)
- Thöny, B.; Ng, J.; Kurian, M.A. et al. (2024). Mouse models for inherited monoamine neurotransmitter disorders. (external link)
- Tai, Mary Dayne Sia; Gamiz-Arco, Gloria; Martinez, Aurora (2024). Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms. (external link)
2023
- Wormdahl, Sofie Breisnes; Kleppe, Rune; Martinez, Aurora et al. (2023). Effect of simulated saturation diving on dopamine synthesis regulation. (external link)
- Mahmud, Md Ekhtear; Støve, Svein Isungset; Martinez, Aurora (2023). Towards the therapeutic correction of mitochondrial Complex I deficiency in dopaminergic cell models. (external link)