2024
-
Flygt, Hjalmar; Söderlund, Stina; Richter, Johan
et al. (2024). Correction to: Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial (Leukemia, (2024), 10.1038/s41375-024-02145-6). (external link)
-
Hemminki, Kari; Zitricky, Frantisek; Försti, Asta
et al. (2024). Age-specific survival in acute myeloid leukemia in the Nordic countries through a half century. (external link)
-
Cuminetti, Vincent; Konieczny, Joanna; Bernal Mera, Aurora
et al. (2024). Succinate receptor 1 signaling regulates hematopoiesis via S100/a8 and S100/a9 in health and malignancy. (external link)
-
Sefland, Øystein; Gullaksen, Stein-Erik; Omsland, Maria
et al. (2024). Mass cytometric single cell immune profiles of peripheral blood from acute myeloid leukemia patients in complete remission with measurable residual disease. (external link)
-
Venanzi, Alessandra; Cardinali, Valeria; Perriello, Vincenzo
et al. (2024). Starry sky pattern predicts RAS pathway activation in NPM1-mutated acute myeloid leukemia. (external link)
-
Ha, Trung Quang; Andresen, Vibeke; Erikstein, Bjarte Skoe
et al. (2024). Preclinical activity of resazurin in acute myeloid leukaemia. (external link)
-
Caulier, Benjamin William; Joaquina, Sandy; Gelebart, Pascal Francois
et al. (2024). CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia. (external link)
-
Flygt, Hjalmar; Söderlund, Stina; Richter, Johan
et al. (2024). Treatment-free remission after a second TKI discontinuation attempt in patients with Chronic Myeloid Leukemia re-treated with dasatinib – interim results from the DAstop2 trial. (external link)
-
Khan, Alesia A.; James, Daniel; Andresen, Vibeke
et al. (2024). Pre-B acute lymphoblastic leukemia presenting with NPM1 and FLT3 mutations. (external link)
-
Eldfors, Samuli; Saad, Joseph; Ikonen, Nemo
et al. (2024). Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia. (external link)
-
Kleftogiannis, Dimitrios; Gavasso, Sonia; Tislevoll, Benedicte Sjo
et al. (2024). Automated cell type annotation and exploration of single-cell signaling dynamics using mass cytometry. (external link)
-
Helland, Åslaug; Steinskog, Eli Sihn Samdal; Blix, Egil Støre
et al. (2024). Hever kvaliteten på behandling av kreft. (external link)
-
Lygre, Kristin Bentung; Forthun, Rakel Brendsdal; Høysæter, Trude
et al. (2024). Assessment of postoperative circulating tumour DNA to predict early recurrence in patients with stage I–III right-sided colon cancer: prospective observational study. (external link)
2023
-
Tettero, Jesse M.; Buisman, Yara; Ngai, Lok Lam
et al. (2023). Prognostic Significance of Measurable Residual Disease Detection by Flow Cytometry in Autologous Stem Cell Apheresis Products in AML. (external link)
-
Thomsen, Liv Cecilie Vestrheim; Honore, Alfred; Gjertsen, Bjørn Tore
et al. (2023). A prospective non-randomized phase I trial of dendritic cell–based cryoimmunotherapy combined with checkpoint inhibitors in mCRPC.. (external link)
-
Thomsen, Liv Cecilie Vestrheim; Honore, Alfred; Reisæter, Lars Anders Rokne
et al. (2023). Survival and biomarkers in a prospective non-randomized phase I trial of dendritic cell-based cryoimmunotherapy combined with checkpoint inhibitors in metastatic castration-resistant prostate cancer (mCRPC). (external link)
-
Rosti, Gianantonio; Brümmendorf, Tim H.; Gjertsen, Bjørn Tore
et al. (2023). Impact of age and comorbidities on the efficacy and tolerability of bosutinib in previously treated patients with chronic myeloid leukemia: results from the phase 4 BYOND study. (external link)
-
Tvedt Skarstein, Andreas; Hoang, Tuyen; Haugen, Hallvard
et al. (2023). In vitro Study of STAT3-inhibitors in Drug-Resistant Chronic Myeloid Leukemia (CML). (external link)
-
Thomsen, Liv Cecilie Vestrheim; Honore, Alfred; Reisæter, Lars Anders Rokne
et al. (2023). A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer. (external link)
-
Othman, Jad; Meggendorfer, Manja; Tiacci, Enrico
et al. (2023). Overlapping features of therapy-related and de novo NPM1-mutated AML. (external link)
-
Ngai, Lok Lam; Hanekamp, Diana; Janssen, Fleur
et al. (2023). Prospective validation of the prognostic relevance of CD34<sup>+</sup>CD38<sup>–</sup> AML stem cell frequency in the HOVON-SAKK132 trial. (external link)
-
Tislevoll, Benedicte Sjo; Hellesøy, Monica; Fagerholt, Oda Helen Eck
et al. (2023). Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia (Nature Communications, (2023), 14, 1, (115), 10.1038/s41467-022-35624-4). (external link)
-
Falini, Brunangelo; Gjertsen, Bjørn Tore; Andresen, Vibeke
(2023). The acidic stretch and the C-terminal nuclear export signal motif of NPM1 mutant: are they druggable in AML?. (external link)
-
Falini, Brunangelo; Martelli, Maria Paola; Brunetti, Lorenzo
et al. (2023). The NPM1 mutant defines AML irrespective of blast count. (external link)
-
Geelen, Inge G.P.; Gullaksen, Stein-Erik; Ilander, Mette M.
et al. (2023). Switching from imatinib to nilotinib plus pegylated interferon-α2b in chronic phase CML failing to achieve deep molecular response: clinical and immunological effects. (external link)
-
Tislevoll, Benedicte Sjo; Hellesøy, Monica; Fagerholt, Oda Helen Eck
et al. (2023). Early response evaluation by single cell signaling profiling in acute myeloid leukemia. (external link)
-
Fløisand, Yngvar; Remberger, Mats; Bigalke, Iris
et al. (2023). WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy. (external link)
-
Tettero, Jesse M.; Ngai, Lok Lam; Bachas, Costa
et al. (2023). Measurable residual disease-guided therapy in intermediate-risk acute myeloid leukemia patients is a valuable strategy in reducing allogeneic transplantation without negatively affecting survival. (external link)
-
Hokland, Peter; Fernández, Isolda I.; Freeman, Sylvie D.
et al. (2023). AML in the elderly—A global view. (external link)
-
Thomsen, Liv Cecilie Vestrheim; Honore, Alfred; Reisæter, Lars Anders Rokne
et al. (2023). Survival and biomarkers in a prospective non-randomized phase I trial of dendritic cell-based cryoimmunotherapy combined with checkpoint inhibitors in metastatic castration-resistant prostate cancer (mCRPC) . (external link)
2022
-
Jenssen, Astrid Bjørke; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Kankuri, Esko
et al. (2022). Administration Methods of Mesenchymal Stem Cells in the Treatment of Burn Wounds. (external link)
-
Tettero, Jesse M.; Al-Badri, Waleed K. W.; Ngai, Lok Lam
et al. (2022). Concordance in measurable residual disease result after first and second induction cycle in acute myeloid leukemia: An outcome- and cost-analysis. (external link)
-
Tislevoll, Benedicte Sjo; Hellesøy, Monica; Fagerholt, Oda Helen Eck
et al. (2022). Early response evaluation by single cell signaling profiling in acute myeloid leukemia. (external link)
-
Kleftogiannis, Dimitrios; Tislevoll, Benedicte Sjo; Hellesøy, Monica
et al. (2022). Identifying predictors of survival in patients with leukemia using single-cell mass cytometry and machine learning. (external link)
-
Helland, Åslaug; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live
et al. (2022). Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway (Journal of Translational Medicine, (2022), 20, 1, (225), 10.1186/s12967-022-03432-5). (external link)
-
Helland, Åslaug; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live
et al. (2022). Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway. (external link)
-
Pianigiani, Giulia; Rocchio, Francesca; Peruzzi, Sara
et al. (2022). The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein. (external link)
-
Huuhtanen, Jani; Ilander, Mette; Yadav, Bhagwan
et al. (2022). IFN-α with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia. (external link)
-
Tasken, Kjetil; Russnes, Hege Elisabeth Giercksky; Aas, Eline
et al. (2022). A national precision cancer medicine implementation initiative for Norway. (external link)
2021
-
Flygt, Hjalmar; Söderlund, Stina; Stentoft, Jesper
et al. (2021). Long-term tolerability and efficacy after initial PegIFN-α addition to dasatinib in CML-CP: Five-year follow-up of the NordCML007 study. (external link)
-
Sletta, Kristine Yttersian; Marin, Oriol Castells; Gjertsen, Bjørn Tore
(2021). Colony stimulating factor 1 receptor in acute myeloid leukemia. (external link)
-
Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten
et al. (2021). Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System . (external link)
-
Rana, Neha; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub
et al. (2021). Systemic and local innate immune responses to surgical co-transplantation of mesenchymal stromal cells and biphasic calcium phosphate for bone regeneration. (external link)
-
Malani, Disha; Adish Kumar, Kumar; Brück, Oscar
et al. (2021). Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia. (external link)
-
Ngai, Lok Lam; Ma, Connie Y.; Maguire, Orla
et al. (2021). Bimodal expression of potential drug target CLL-1 (CLEC12A) on CD34+ blasts of AML patients. (external link)
-
Kreitman, Robert J.; Dearden, Claire; Zinzani, Pier Luigi
et al. (2021). Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial. (external link)
-
Löwenberg, Bob; Pabst, Thomas; Maertens, Johan
et al. (2021). Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: The HOVON-SAKK-132 trial. (external link)
-
Janssen, Jeroen; Löwenberg, Bob; Manz, Markus
et al. (2021). Inferior outcome of addition of the aminopeptidase inhibitor tosedostat to standard intensive treatment for elderly patients with aml and high risk mds. (external link)
-
Bakunina, Katerina; Putter, Hein; Versluis, Jurjen
et al. (2021). The added value of multi-state modelling in a randomized controlled trial: The HOVON 102 study re-analyzed. (external link)
-
Johansen, Silje; Lægreid, Ingvild Jenssen; Ernstsen, Siw Leiknes
et al. (2021). Thrombosis and thrombocytopenia after HPV vaccination. (external link)
-
Gundersen, Edvin Tang; Førde, Jan-Lukas; Tislevoll, Benedicte Sjo
et al. (2021). Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation. (external link)
-
Jaffredo, Thierry; Balduini, Alessandra; Bigas, Anna
et al. (2021). The eha research roadmap: normal hematopoiesis. (external link)
-
Hellesøy, Monica; Engen, Caroline Benedicte Nitter; Grob, Tim
et al. (2021). Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis. (external link)
-
Bredrup, Cecilie; Cristea, Ileana; Safieh, Leen Abu
et al. (2021). Temperature-dependent autoactivation associated with clinical variability of PDGFRB Asn666 substitutions. (external link)
-
Anandan, Shamundeeswari; Thomsen, Liv Cecilie Vestrheim; Gullaksen, Stein-Erik
et al. (2021). Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods. (external link)
-
Mosleth, Ellen Færgestad; Vedeler, Christian Alexander; Liland, Kristian Hovde
et al. (2021). Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis. (external link)
-
Rana, Neha; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub
et al. (2021). Systemic monocyte-macrophage response to co-transplanting mesenchymal stromal cells and biphasic calcium phosphate biomaterial for bone regeneration. (external link)
-
Shafiee, Sahba; Gelebart, Pascal Francois; Popa, Mihaela-Lucia
et al. (2021). Preclinical characterisation and development of a novel myelodysplastic syndrome-derived cell line. (external link)
-
Haaland, Ingvild; Hjelle, Sigrun Margrethe; Reikvam, Håkon
et al. (2021). p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy. (external link)
-
Engen, Caroline ; Hellesøy, Monica; Grob, Tim
et al. (2021). FLT3-ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation. (external link)
2020
-
Omsland, Maria; Andresen, Vibeke; Gullaksen, Stein-Erik
et al. (2020). Tyrosine kinase inhibitors and interferon‐α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines (. (external link)
-
Kleinmanns, Katrin; Bischof, Katharina; Anandan, Shamundeeswari
et al. (2020). CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma. (external link)
-
Engen, Caroline Benedicte Nitter; Gjertsen, Bjørn Tore; Bruserud, Øystein
et al. (2020). Exploring the boundaries of precision haemato-oncology – The case of FLT3 length mutated acute myeloid leukaemia. (external link)
-
Haugse, Ragnhild; Langer, Anika; Murvold, Elisa Thodesen
et al. (2020). Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells. (external link)
-
Mercatelli, Daniele; Bortolotti, Massimo; Andresen, Vibeke
et al. (2020). Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling. (external link)
-
Bjånes, Tormod Karlsen; Kotopoulis, Spiros; Murvold, Elsa Thodesen
et al. (2020). Ultrasound‐ and microbubble‐assisted gemcitabine
delivery to pancreatic cancer cells. (external link)
-
Alme, Eirin; Törnroos, Karl Wilhelm; Gjertsen, Bjørn Tore
et al. (2020). Synthesis of N-aryl- and N-alkyl-substituted imidazolium silver complexes: Cytotoxic screening by using human cell lines modelling acute myeloid leukaemia. (external link)
-
Hochhaus, Andreas; Gambacorti-Passerini, Carlo; Abboud, Camille
et al. (2020). Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia: primary results of the phase 4 BYOND study. (external link)
-
Majumder, Muntasir M.; Leppä, Aino-Maija; Hellesøy, Monica
et al. (2020). Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types. (external link)
-
Tadele, Dagim Shiferaw; Robertson, Joseph; Crispin, Richard
et al. (2020). A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation. (external link)
-
Bjørsvik, Hans-René; Gjertsen, Bjørn Tore; Elumalai, Vijayaragavan
(2020). Hit to leads with cytotoxic effect in leukemic cells: Total synthesis intermediates as a molecule treasure chest. (external link)
-
Kuusanmäki, Heikki; Leppä, Aino-Maija; Pölönen, Petri
et al. (2020). Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia. (external link)
-
Tambe, Mahesh; Karjalainen, Ella; Vähä-Koskela, Markus
et al. (2020). Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition. (external link)
-
Onyango, Therese Bredholt; Hjelle, Sigrun Margrethe; Haaland, Ingvild
et al. (2020). A comparison of p53 isoform profiles and apoptosis induced by camptothecin or a herbal khat extract (Catha edulis (vahl) forssk. ex endl.) in leukemic cell lines: Exploring cellular responses in therapy development. (external link)
-
Wang, Xiang; Deng, Linhong; Gjertsen, Bjørn Tore
(2020). A microfluidic device for differential capture of heterogeneous rare tumor cells with epithelial and mesenchymal phenotypes. (external link)
-
Fagerholt, Oda Helen Eck; Hellesøy, Monica; Gullaksen, Stein-Erik
et al. (2020). Single cell detection of the p53 protein by mass cytometry. (external link)
-
Ossenkoppele, G.J.; Breems, D.A.; Stuessi, G.
et al. (2020). Correction: Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS (Leukemia, (2020), 34, 7, (1751-1759), 10.1038/s41375-020-0725-0). (external link)
-
Ossenkoppele, G.J.; Breems, D.A.; Stuessi, G.
et al. (2020). Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS. (external link)
2019
-
Bischof, Katharina; Bjørge, Line; Gjertsen, Bjørn Tore
et al. (2019). Rethinking Gynecological High-
Grade Serous Carcinoma. Portraying the p53 isoform landscape and development of a new
preclinical for optical imaging in xenograft models. (external link)
-
Gullaksen, Stein-Erik; Bader, Lucius; Hellesøy, Monica
et al. (2019). Titrating complex mass cytometry panels. (external link)
-
Bischof, Katharina; Knappskog, Stian; Hjelle, Sigrun Margrethe
et al. (2019). Influence of p53 isoform expression on survival in high-grade serous ovarian cancers. (external link)
-
Kreutzman, Anna; Yadav, Bhagwan; Brümmendorf, Tim H.
et al. (2019). Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line. (external link)
-
Haugse, Ragnhild; Langer, Anika; Gullaksen, Stein-Erik
et al. (2019). Intracellular signaling in key pathways is induced by treatment with ultrasound and microbubbles in a leukemia cell line, but not in healthy peripheral blood mononuclear cells. (external link)
-
Zhang, Beibei; Ayuda-Duran, Maria del Pilar; Piechaczyk, Laure Isabelle
et al. (2019). GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells. (external link)
-
Andresen, Vibeke; Gjertsen, Bjørn Tore
(2019). Clinical trials of repurposing medicines in acute myeloid leukemia: Limitations and possibilities in the age of precision therapy. (external link)
-
Jebsen, Nina Louise; Apelseth, Torunn Oveland; Haugland, Hans Kristian
et al. (2019). Enhanced T-lymphocyte infiltration in a desmoid tumor of the thoracic wall in a young woman treated with intratumoral injections of the oncolytic peptide LTX-315: A case report. (external link)
-
Gras Navarro, Andrea; Espedal, Heidi; Vareecal Joseph, Justin
et al. (2019). Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival. (external link)
-
Lundevall, Frida Johanne; Bedringaas, Siv Lise; Törnroos, Karl Wilhelm
et al. (2019). Synthesis and investigation of Ag-NHC complexes with cytotoxic properties towards cell lines modelling acute myeloid leukemia . (external link)
-
Grønningsæter, Ida Sofie; Fredly, Hanne Kristin; Gjertsen, Bjørn Tore
et al. (2019). Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy.. (external link)
-
Forthun, Rakel Brendsdal; Hovland, Randi; Schuster, Cornelia
et al. (2019). ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab. (external link)
-
Rahman, Mohummad Aminur; Gras Navarro, Andrea; Brekke, Jorunn
et al. (2019). Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival. (external link)
-
Gjertsen, Bjørn Tore; Tislevoll, Benedicte Sjo; Fagerholt, Oda Helen Eck
et al. (2019). Early response evaluation in AML using mass cytometry. (external link)
-
Forthun, Rakel Brendsdal; Hellesøy, Monica; Sulen, Andre
et al. (2019). Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia. (external link)
2018
-
Jørgensen, Katarina Mariann; Mosleth, Ellen Færgestad; Liland, Kristian Hovde
et al. (2018). Gene expression response in peripheral blood cells of petroleum workers exposed to sub-ppm benzene levels. (external link)
-
Reikvam, Håkon; Skavland, Jørn; Gullaksen, Stein-Erik
et al. (2018). Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation. (external link)
-
Schuster, Cornelia; Gausdal, Gro; Gjertsen, Bjørn Tore
et al. (2018). Update on the randomised phase Ib/II study of the selective small molecule AXL inhibitor bemcentinib (BGB324) in combination with either dabrafenib/trametinib or pembrolizumab in patients with metastatic melanoma. (external link)
-
Bischof, Katharina; Knappskog, Stian; Stefansson, Ingunn
et al. (2018). High expression of the p53 isoform ? is associated with reduced progression-free survival in uterine serous carcinoma. (external link)
-
Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Hellem, Sølve
et al. (2018). Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial. . (external link)
-
Nepstad, Ina; Hatfield, Kimberley Joanne; Aasebø, Elise
et al. (2018). Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic and transcriptomic comparison. (external link)
-
Kirkeleit, Jorunn; Riise, Trond; Bjørge, Tone
et al. (2018). Maternal exposure to gasoline and exhaust increases the risk of childhood leukaemia in offspring - a prospective study in the Norwegian Mother and Child Cohort Study. (external link)
-
Brattås, Marte Karen; Lilleeng, Kyrre Flattun; Hovland, Randi
et al. (2018). Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis. (external link)
-
Kreitman, Robert J.; Dearden, Claire; Zinzani, Pier Luigi
et al. (2018). Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia. (external link)
-
Omsland, Maria; Pise-Masison, Cynthia A.; Fujikawa, Dai
et al. (2018). Inhibition of tunneling nanotube (TNT) formation and Human T-cell leukemia virus type 1 (HTLV-1) transmission by cytarabine. (external link)
-
Gullaksen, Stein-Erik; Gjertsen, Bjørn Tore; Kirkeleit, Jorunn
et al. (2018). Single cell signalling and
immune profiles in chronic
myeloid leukaemia
. (external link)
2017
-
Sopper, Sieghart; Mustjoki, Satu; Gjertsen, Bjørn Tore
et al. (2017). NK cell dynamics and association with molecular response in early chronic phase chronic myelogenous leukemia (CML-CP) patients treated with nilotinib. (external link)
-
Sabir, Misbah; Hellesøy, Monica; Kivioja, Jarno
et al. (2017). development of novel Highly Specific FLT3 Targeted Inhibitors for Combination or Sequential Therapy of Acute Myeloid Leukemia. (external link)
-
Karjalainen, Riikka; Popa, Mihaela Lucia; Liu, M
et al. (2017). Stroma-derived factors stimulate JAK/STAT signaling in AML cells resulring in resistance to BCL2 inhibitor Venetoclax. (external link)
-
Ayuda-Duran, Maria del Pilar; Zhang, B; Piechaczyck, L.
et al. (2017). a precision medicin platform for acute myeloid leukemia to help unraveling the molecular addictions of FLT3-ITD-driven AML. (external link)
-
Kotopoulis, Spiros; Stigen, Endre; Popa, Mihaela Lucia
et al. (2017). Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma. (external link)
-
Gullaksen, Stein-Erik; Skavland, Jørn; Gavasso, Sonia
et al. (2017). Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib. (external link)
-
Reikvam, Håkon; Hovland, Randi; Forthun, Rakel Brendsdal
et al. (2017). Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia - identification of responders by gene expression profiling of pretreatment leukemic cells. (external link)
-
Karjalainen, Riikka; Pemovska, Tea; Popa, Mihaela Lucia
et al. (2017). JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML. (external link)
-
Omsland, Maria; Bruserud, Øystein; Gjertsen, Bjørn Tore
et al. (2017). Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-KB inhibition in acute myeloid leukemia (AML). (external link)
-
Rajala, Hanna L.M.; El Missiry, Mohamed; Ruusila, Anniina
et al. (2017). Tyrosine kinase inhibitor therapy-induced changes in humoral immunity in patients with chronic myeloid leukemia. (external link)
-
Gjertsen, Bjørn Tore
(2017). Proteomics and single cell immune and signaling profiling of myeloid leukemia. (external link)
-
Kontro, Mika; Kumar, Anil; Majumder, Muntasir Mamun
et al. (2017). HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia. (external link)
-
Andresen, Vibeke; Gjertsen, Bjørn Tore
(2017). Drug Repurposing for the Treatment of Acute Myeloid Leukemia. (external link)
-
Laukkanen, S; Grönroos, T; Pölönen, P
et al. (2017). In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL. (external link)
-
Lowenberg, Bob; Pabst, Thomas; Maertens, Johan
et al. (2017). Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML. (external link)
-
Jebsen, Nina Louise; Scarlett, Samantha; Magnusdottir, Bergrun Tinna
et al. (2017). Biomarker Panels and Contemporary Practice in Clinical Trials of Targeted Therapy. (external link)
-
Forthun, Rakel Brendsdal; Aasebø, Elise; Rasinger, Josef Daiel
et al. (2017). Phosphoprotein DIGE profiles reflect blast differentiation, cytogenetic risk stratification, FLT3/NPM1 mutations and therapy response in acute myeloid leukaemia. (external link)
-
Sopper, Sieghart; Mustjoki, Satu; White, Deborah
et al. (2017). Reduced CD62L expression on T cells and increased soluble CD62L levels predict molecular response to tyrosine kinase inhibitor therapy in early chronic-phase chronic myelogenous leukemia. (external link)
-
Forthun, Rakel Brendsdal; Sulen, Andre; Sjøholt, Gry
et al. (2017). combination of interferon-alpha and valproic acid in acute myeloid leukemia cells in vitro and in vivo. (external link)
2016
-
Dimcevski, Georg Gjorgji; Kotopoulis, Spiros; Bjånes, Tormod Karlsen
et al. (2016). A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer. (external link)
-
Hjorth-Hansen, Henrik; Stentoft, Jesper; Richter, Johan
et al. (2016). Safety and efficacy of the combination of pegylated interferon-α2b and dasatinib in newly diagnosed chronic-phase chronic myeloid leukemia patients. (external link)
-
Sulen, Andre; Gullaksen, Stein-Erik; Bader, Lucius
et al. (2016). Signaling effects of sodium hydrosulfide in healthy donor peripheral blood mononuclear cells. (external link)
-
Sulen, Andre; Gjertsen, Bjørn Tore
(2016). Leukocyte p38 and p53 proteins after environmental exposure; variation, associations and applicability. (external link)
-
Thielen, Noortje; Richter, Johan; Baldauf, Matthias
et al. (2016). Leukemic stem cell quantification in newly diagnosed patients with chronic myeloid leukemia predicts response to nilotinib therapy. (external link)
-
Helland, Øystein; Popa, Mihaela Lucia; Bischof, Katharina
et al. (2016). The HDACi panobinostat shows growth inhibition both in vitro and in a bioluminescent orthotopic surgical xenograft model of ovarian cancer. (external link)
-
Engen, Caroline Benedicte Nitter; Hajjar, Ehsan; Gjertsen, Bjørn Tore
(2016). Development of personalized molecular therapy for acute myeloid leukemia. (external link)
-
Andresen, Vibeke; Erikstein, Bjarte Skoe; Mukherjee, Herschel
et al. (2016). Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia. (external link)
-
Kotopoulis, Spiros; Dimcevski, Georg Gjorgji; Mc Cormack, Emmet
et al. (2016). Ultrasound- and microbubble-enhanced chemotherapy for treating pancreatic cancer: A phase I clinical trial. (external link)
-
Kotopoulis, Spiros; Dimcevski, Georg Gjorgji; McCormack, Emmet
et al. (2016). Ultrasound- and microbubble-enhanced chemotherapy for treating pancreatic cancer: a phase I clinical trial. (external link)
-
Gavasso, Sonia; Gullaksen, Stein-Erik; Skavland, Jørn
et al. (2016). Single-cell proteomics: Potential implications for cancer diagnostics. (external link)
-
Leitch, Calum; Osdal, Tereza; Andresen, Vibeke
et al. (2016). Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia. (external link)
-
Dimcevski, Georg Gjorgji; Kotopoulis, Spiros; Bjånes, Tormod Karlsen
et al. (2016). Ultrasound and microbubble enhanced treatment of inoperable pancreatic adeonocarcinoma. (external link)
-
Sulen, Andre; Lygre, Stein Håkon Låstad; Hjelle, Sigrun Margrethe
et al. (2016). Elevated monocyte phosphorylated p38 in nearby employees after a chemical explosion. (external link)
2015
-
Sandtorv, Alexander Harald; Leitch, Calum; Bedringaas, Siv Lise
et al. (2015). 4-alkylated silver-N-heterocyclic carbene (NHC) complexes with cytotoxic effects in leukemia cells. (external link)
-
Myklebost, Ola; Lothe, Ragnhild A; Gjertsen, Bjørn Tore
et al. (2015). Bør hver kreftpasient bli et eget forskningsprosjekt?. (external link)
-
Bruserud, Øystein; Reikvam, Håkon; Fredly, Hanne Kristin
et al. (2015). Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation. (external link)
-
Landskron, Johannes; Helland, Øystein; Torgersen, Knut Martin
et al. (2015). Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients. (external link)
-
Landskron, Johannes; Helland, Øystein; Torgersen, Knut Martin
et al. (2015). Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients. (external link)
-
Kotopoulis, Spiros; Popa, Mihaela Lucia; Safont, MJ
et al. (2015). Sonoporation using Acoustic Cluster Therapy in combination With chemotherapy transiently reduces tumour volume.. (external link)
-
Kotopoulis, Spiros; Popa, Mihaela Lucia; Safont, MJ
et al. (2015). Sonoporation using Acoustic Cluster Therapy in combination With chemotherapy transiently reduces tumour volume.. (external link)
-
Gjertsen, Bjørn Tore; Schöffski, Patrick
(2015). Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy. (external link)
-
Hjorth-Hansen, Henrik; Stenke, Leif; Söderlund, Stina
et al. (2015). Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: Clinical results from a randomised phase-2 study (NordCML006). (external link)
-
Mukherjee, Herschel; Chan, Kok-Ping; Andresen, Vibeke
et al. (2015). Interactions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 mediate the cellular localization of nucleophosmin and its aml-associated mutants. (external link)
2014
-
Kotopoulis, Spiros; Delalande, Anthony; Popa, Mihaela Lucia
et al. (2014). Sonoporation-enhanced chemotherapy significantly reduces primary tumour burden in an orthotopic pancreatic cancer xenograft. (external link)
-
Kotopoulis, Spiros; Dimcevski, Georg Gjorgji; Gjertsen, Bjørn Tore
et al. (2014). Sonoporation: from the lab to human clinical trials. (external link)
-
Kotopoulis, Spiros; Haugse, Ragnhild; Mujic, Maja
et al. (2014). Evaluation of the effects of clinical diagnostic ultrasound in combination with ultrasound contrast agents on cell stress: Single cell analysis of intracellular phospho-signaling pathways in blood cancer cells and normal blood leukocytes. (external link)
-
Helland, Øystein; Popa, Mihaela Lucia; Vintermyr, Olav Karsten
et al. (2014). First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma. (external link)
-
Li, Ling; Osdal, Tereza; Ho, Yinway
et al. (2014). SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells. (external link)
-
Andresen, Vibeke; Omsland, Maria; Gjertsen, Bjørn Tore
et al. (2014). Cell-to-Cell Communication in Acute Myeloid Leukemia by Tunneling Nanotubes. (external link)
-
Kontro, M; Kuusanmäki, H; Eldfors, S
et al. (2014). Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia. (external link)
-
Hampson, Peter; Wang, Keqing; Ersvær, Elisabeth
et al. (2014). Up-regulation of anti-apoptotic genes confers resistance to the novel anti-leukemic compound PEP005 in primary AML cells. (external link)
-
Aasebø, Elise; Vaudel, Marc; Mjaavatten, Olav
et al. (2014). Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines. (external link)
-
Gjertsen, Bjørn Tore
(2014). Mot en mer spesifikk kreftbehandling? :. (external link)
-
Rizzieri, David A.; Vey, Norbert; Thomas, Xavier
et al. (2014). A phase II study of elacytarabine in combination with idarubicin and of human equilibrative nucleoside transporter 1 expression in patients with acute myeloid leukemia and persistent blasts after the first induction course. (external link)
-
Haaland, Ingvild; Opsahl, Jill Anette; Berven, Frode
et al. (2014). Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia. (external link)
-
Gavasso, Sonia; Mosleth, Ellen Færgestad; Marøy, Tove Helene
et al. (2014). Deficient phosphorylation of stat-1 in leukocytes identifies neutralizing antibodies in multiple sclerosis patients treated with interferon-beta. (external link)
-
Engen, Caroline Benedicte Nitter; Wergeland, Line; Skavland, Jørn
et al. (2014). Targeted Therapy of FLT3 in Treatment of AML-Current Status and Future Directions. (external link)
2013
-
McCormack, Emmet ; Silden, Elisabeth; West, Richard M.
et al. (2013). Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer. (external link)
-
Silden, Elisabeth; Hjelle, Sigrun Margrethe; Wergeland, Line
et al. (2013). Expression of TP53 isoforms p53 beta or p53 gamma enhances chemosensitivity in TP53(null) cell lines. (external link)
-
McCormack, Emmet ; Mujic, Maja; Osdal, Tereza
et al. (2013). Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia. (external link)
-
Kotopoulis, Spiros; Delalande, Anthony; Popa, Mihaela
et al. (2013). Ultrasound and microbubble enhanced therapy of orthotopic human pancreatic cancer in mice. (external link)
-
Dimcevski, Georg Gjorgji; Kotopoulis, Spiros; Hoem, Dag
et al. (2013). Ultrasound-assisted treatment of an inoperable pancreatic cancer. (external link)
-
Mujic, Maja; Haugse, Ragnhild; Kotopoulis, Spiros
et al. (2013). Ultrasound combined with microbubbles modulates signal transduction pathways in blood cells. (external link)
-
Helland, Øystein; Popa, Mihaela Lucia; Gjertsen, Bjørn Tore
et al. (2013). Panobinostat / carboplatin delay postsurgical relapse of ovarian carcinomas in an orthotopic mouse model. (external link)
-
Fredly, Hanne Kristin; Gjertsen, Bjørn Tore; Bruserud, Øystein
(2013). Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents. (external link)
-
Fredly, Hanne Kristin; Ersvær, Elisabeth; Kittang, Astrid Marta Olsnes
et al. (2013). The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia. (external link)
-
Helland, Øystein; Bishof, Katharina; Popa, Mihaela Lucia
et al. (2013). Histone deacetylase inhibisjon i kombinasjon med platinum i en klinisk relevant ortotopisk musemodel for ovarialcancer. (external link)
-
Helland, Øystein; Mihaela, P.; Gjertsen, Bjørn Tore
et al. (2013). PANOBINOSTAT / CARBOPLATIN DELAY POSTSURGICAL RELAPSE OF OVARIAN CARCINOMA IN AN ORTHOTOPIC MOUSE MODEL. (external link)
-
Reikvam, Håkon; Kittang, Astrid Marta Olsnes; Melve, Guro Kristin
et al. (2013). Targeted anti-leukemic therapy as disease-stabilizing treatment for acute myeloid leukemia relapse after allogeneic stem cell transplantation: will it be possible to combine these strategies with retransplantation or donor lymphocyte infusions?. (external link)
-
Gausdal, Gro; Wergeland, Anita; Skavland, Jørn
et al. (2013). Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. (external link)
-
Øye, Ola Kristoffer; Jørgensen, Katarina Mariann; Hjelle, Sigrun Margrethe
et al. (2013). Gel2DE-A software tool for correlation analysis of 2D gel electrophoresis data. (external link)
-
Herfindal, Lars; Myhren, Lene Elisabeth; Gjertsen, Bjørn Tore
et al. (2013). Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen. (external link)
-
Andresen, Vibeke; Wang, Xiang; Ghimire, Sakhila
et al. (2013). Tunneling nanotube (TNT) formation is independent of p53 expression. (external link)
-
Gjertsen, Bjørn Tore
(2013). Phosphoprotein signaling in acute myeloid leukemia. (external link)
-
Pemovska, Tea; Kontro, Mika; Yadav, Bhagwan
et al. (2013). Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia. (external link)
-
Mustjoki, Satu; Richter, Johan; Barbany, Gisela
et al. (2013). Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients. (external link)
-
Reikvam, Håkon; Nepstad, Ina; Sulen, Andre
et al. (2013). Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors. (external link)
-
McCormack, Emmet ; Adams, Katherine J.; Hassan, Namir J.
et al. (2013). Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1-and LAGE-1-positive tumors. (external link)
-
Kloster, Martine Müller; Naderi, Elin Hallan; Haaland, Ingvild
et al. (2013). cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases. (external link)
-
Bredholt, Therese; Ersvær, Elisabeth; Erikstein, Bjarte Skoe
et al. (2013). Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine. (external link)
-
Engen, Caroline Benedicte Nitter; Wergeland, Line; Gjertsen, Bjørn Tore
(2013). Målrettet behandling av akutt myelogen leukemi - hemmere mot FLT3 og andre kinaser viser vei. (external link)
2012
-
Delalande, Anthony; Kotopoulis, Spiros; Pichon, Chantal
et al. (2012). Microbubbles and cell interactions. (external link)
-
Reikvam, Håkon; Hatfield, Kimberley Joanne; Ersvær, Elisabeth
et al. (2012). Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status - consequences and potentials for pharmacological intervention. (external link)
-
McCormack, Emmet Martin; Haaland, Ingvild; Venås, Gurid
et al. (2012). Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia. (external link)
-
Ånensen, Nina; Hjelle, Sigrun Margrethe; Van, Belle Werner
et al. (2012). Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia. (external link)
-
Hjelle, Sigrun Margrethe; Sulen, Andre; Øye, Ola Kristoffer
et al. (2012). Leukocyte p53 protein biosignature through standard-aligned two-dimensional immunoblotting. (external link)
-
Oveland, Eystein; Wergeland, Line; Hovland, Randi
et al. (2012). Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines. (external link)
-
Mujic, Maja; Kotopoulis, Spiros; Delalande, Anthony
et al. (2012). Flow cytometic characterization and sorting of ultrasound contrast agents. (external link)
-
Fredly, Hanne Kristin; Reikvam, Håkon; Gjertsen, Bjørn Tore
et al. (2012). Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: Serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment. (external link)
-
Gavasso, Sonia; Gjertsen, Bjørn Tore; Anderssen, Endre
et al. (2012). Immunogenic effects of recombinant interferon-beta therapy disrupt the JAK/STAT pathway in primary immune cells from patients with multiple sclerosis. (external link)
-
Giles, Francis; Mahon, François-Xavier; Gjertsen, Bjørn Tore
et al. (2012). Developmental Therapeutics Consortium report on study design effects on trial outcomes in chronic myeloid leukaemia. (external link)
-
Gjertsen, Bjørn Tore; Wiig, Helge
(2012). Investigation of therapy resistance mechanisms in myeloid leukemia by protein profiling of bone marrow extracellular fluid. (external link)
-
Bjugn, Roger; Gjertsen, Bjørn Tore
(2012). Human cells and the Norwegian Health Research Act. (external link)
-
Øye, Ola Kristoffer; Ulvang, Dag Magne; Jørgensen, Katarina Mariann
et al. (2012). Volume visualization for exploration of population trends in two-dimensional gel electrophoresis protein data. (external link)
-
Helland, Øystein; Popa, Mihaela Lucia; Vintermyr, Olav Karsten
et al. (2012). Establishment of a bioluminescence orthotopic mouse model of ovarian carcinoma: Analysis of tumor growth and response to therapy. (external link)
-
Rizzieri, David A.; Vey, Norbert; Thomas, Xavier
et al. (2012). A Phase II Study of Elacytarabine/Idarubicin As Second Course Remission-Induction in Patients with Acute Myeloid Leukemia Who Failed Cytarabine/Anthracycline. (external link)
-
Gavasso, Sonia; Marøy, Tove Helene; Mosleth, Ellen Færgestad
et al. (2012). Single cell pStat1 activation, a promising biomarker to evaluate neutralizing antibody effects in interferon-beta treated multiple sclerosis patients. (external link)
-
Hallenborg, Philip; Feddersen, Søren; Francoz, Sarah
et al. (2012). Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation. (external link)
-
Gullaksen, Stein-Erik Uriarte; Micoulet, Alexandre; Gjertsen, Bjørn Tore
(2012). Deformation of acute myeloid leukaemia cells in micro-constriction array; a novel tool to study cell stress signalling. (external link)
-
Tsykunova, Galina; Reikvam, Håkon; Ahmed, Aymen B
et al. (2012). Targeting of polo-like kinases and their cross talk with Aurora kinases - possible therapeutic strategies in human acute myeloid leukemia?. (external link)
-
Forthun, Rakel Brendsdal; Sengupta, Tanima; Skjeldam, Hanne Kim
et al. (2012). Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid. (external link)
2011
-
Gjertsen, Bjørn Tore
(2011). Stratification of pediatric acute myeloid leukemia through cancer cell gene-expression profiling. (external link)
-
Jørgensen, Katarina Mariann; Hjelle, Sigrun Margrethe; Øye, Ola Kristoffer
et al. (2011). Untangling the intracellular signalling network in cancer - a strategy for data integration in acute myeloid leukemia. (external link)
-
Skavland, Jørn; Jørgensen, Katarina Mariann; Hadziavdic, Kenan
et al. (2011). Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia. (external link)
-
Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill
et al. (2011). Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. (external link)
-
Fredly, Hanne Kristin; Ersvær, Elisabeth; Gjertsen, Bjørn Tore
et al. (2011). Immunogenic apoptosis in human acute myeloid leukemia (AML): primary human AML cells expose calreticulin and release heat shock protein (HSP) 70 and HSP90 during apoptosis. (external link)
2010
-
Erikstein, Bjarte Skoe; Hagland, Hanne; Nikolaisen, Julie
et al. (2010). Cellular stress induced by resazurin leads to autophagy and cell death via production of reactive oxygen species and mitochondrial impairment. (external link)
-
Fredly, Hanne Kristin; Bjørnsen, Camilla I. Stapnes; Gjertsen, Bjørn Tore
et al. (2010). Combination of the histone deacetylase inhibitor valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe and effective in patients with advanced acute myeloid leukaemia - a report of five cases. (external link)
-
Hatfield, Kimberley Joanne; Bedringaas, Siv Lise; Gjertsen, Bjørn Tore
et al. (2010). OXYGEN LEVELS INFLUENCE THE CYTOKINE RELEASE PROFILE OF AML CELLS. (external link)
-
Ersvær, Elisabeth; Liseth, Knut; Skavland, Jørn
et al. (2010). Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells. (external link)
-
Skavland, Jørn; Hadziavdic, Kenan; Jonassen, Inge
et al. (2010). Combined epigenetic and signal transduction therapy modulate specific signal transduction patterns in acute myeloid leukemia. (external link)
-
McCormack, Emmet Martin; Skavland, Jørn; Mujic, Maja
et al. (2010). Lentinan: hematopoietic, immunological, and efficacy studies in a syngeneic model of acute myeloid leukemia. (external link)
-
Hatfield, Kimberley Joanne; Bedringaas, Siv Lise; Ryningen, Anita
et al. (2010). Hypoxia increases HIF-1 alpha expression and constitutive cytokine release by primary human acute myeloid leukaemia cells. (external link)
-
Erikstein, Bjarte Skoe; McCormack, Emmet Martin; Tronstad, Karl Johan
et al. (2010). Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. (external link)
-
Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill
et al. (2010). Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. (external link)
-
Semaeva, Elvira; Tenstad, Olav; Skavland, Jørn
et al. (2010). Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation. (external link)
-
Hjelle, Sigrun Margrethe; Forthun, Rakel Brendsdal; Haaland, Ingvild
et al. (2010). Clinical proteomics of myeloid leukemia. (external link)
2009
-
Wang, Jian; Tsinkalovsky, Oleg; Zhao, P
et al. (2009). TARGETING THE TUMOR STROMA: A NOVEL THERAPEUTIC STRATEGY BASED ON SEPARATE ANALYSIS OF THE MALIGNANT AND STROMAL CELL COMPARTMENTS IN BRAIN TUMORS. (external link)
-
Christoffersen, Thoralf; Guren, Tormod K.; Spindler, Karen-Lise Garm
et al. (2009). Cancer therapy targeted at cellular signal transduction mechanisms: strategies, clinical results, and unresolved issues. (external link)
-
Reikvam, Håkon; Olsnes, Astrid Marta; Gjertsen, Bjørn Tore
et al. (2009). Nuclear Factor-kappaB Signaling: A Contributor in Leukemogenesis and a Target for Pharmacological Intervention in Human Acute Myelogenous Leukemia. (external link)
-
Øyan, Anne Margrete; Ånensen, Nina; Bø, Trond Hellem
et al. (2009). Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia. (external link)
-
Ryningen, Anita; Stapnes, Camilla I; Lassalle, Philippe
et al. (2009). A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid. (external link)
-
Oveland, Eystein; Gjertsen, Bjørn Tore; Wergeland, Line
et al. (2009). Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells. (external link)
-
Hofmann, Matthias; McCormack, Emmet Martin; Mujic, Maja
et al. (2009). Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model. (external link)
-
Olsnes, Astrid Marta; Ersvær, Elisabeth; Ryningen, Anita
et al. (2009). The protein kinase C agonist PEP005 increases NF-kB expression, induces differentiation and increases constitutive chemokine release by primary acute myeloid leukaemia cells. (external link)
-
Gjertsen, Bjørn Tore
(2009). Er høyt hemoglobinnivå farlig?. (external link)
-
Hatfield, Kimberley Joanne; Øyan, Anne Margrete; Ersvær, Elisabeth
et al. (2009). Phase II study of subcutaneous alemtuzumab without dose escalation in patients with advanced-stage, relapsed chronic lymphocytic leukaemia. (external link)
-
Christoffersen, Thoralf; Gjertsen, Bjørn Tore; Engebråten, Olav
et al. (2009). Signalhemmere. (external link)
-
Stapnes, Camilla I; Gjertsen, Bjørn Tore; Reikvam, Håkon
et al. (2009). Targeted therapy in acute myeloid leukaemia: current status and future directions. (external link)
-
Hatfield, Kimberley Joanne; Øyan, Anne Margrete; Ersvær, Elisabeth
et al. (2009). Primary human acute myeloid leukaemia cells increase the proliferation of microvascular endothelial cells through the release of soluble mediators. (external link)
-
Bredholt, Therese; Dimba, Elisabeth Anne Okumu; Hagland, Hanne
et al. (2009). Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. (external link)
-
Lukandu, Ochiba Mohammed; Bredholt, Therese; Neppelberg, Evelyn
et al. (2009). Early loss of mitochondrial inner transmembrane potential in khat-induced cell death of primary normal human oral cells. (external link)
2008
-
Kirkeleit, Jorunn; Riise, Trond; Gjertsen, Bjørn Tore
et al. (2008). Effects of benzene on human hematopoiesis. (external link)
-
McCormack, Emmet Martin; Bruserud, Øystein; Gjertsen, Bjørn Tore
(2008). Review: genetic models of acute myeloid leukaemia. (external link)
-
Gjertsen, Bjørn Tore; McCormack, Emmet Martin
(2008). Erythropoietin a safe bet in haemorrhagic shock?. (external link)
-
Bruserud, Øystein; Ersvær, Elisabeth; Olsnes, Astrid Marta
et al. (2008). Anticancer Immunotherapy in Combination with Proapoptotic Therapy. (external link)
-
Gavasso, Sonia; Skavland, Jørn; Gjertsen, Bjørn Tore
et al. (2008). Interferon-beta signal transduction, multiple sclerosis and auto-antibodies. (external link)
-
Wergeland, Line; Oveland, Eystein; Sjøholt, Gry
et al. (2008). FLT3 internal tandem duplication involving its libiquitin dependent endocytosis motif suspend modulation by HDM2 and are associated with inferior survival in AML. (external link)
-
McCormack, Emmet Martin; Haaland, Ingvild; Venås, Gurid
et al. (2008). Evaluation of combinational therapy of MDM2-antagonist nutlin-3 and HDAC-inhibitor valproic acid in acute myeloid leukemia in vitro and in vivo. (external link)
-
Ryningen, Anita; Stapnes, Camilla I; Paulsen, Kristin
et al. (2008). In vivo biological effects of ATRA in the treatment of AML. (external link)
-
Hatfield, Kimberley Joanne; Hovland, Randi; Øyan, Anne Margrete
et al. (2008). Release of angiopoietin-1 by primary human acute myelogenous leukemia cells is associated with mutations of nucleophosmin, increased by bone marrow stromal cells and possibly antagonized by high systemic angiopoietin-2 levels. (external link)
-
Gjertsen, Bjørn Tore; Lorens, James
(2008). Comprehensive Analysis of Gene Function: RNA interference and Chemical Genomics. (external link)
-
Lukandu, Ochiba Mohammed; Costea, Daniela Elena; Dimba, Elisabeth Anne Okumu
et al. (2008). Khat induces G1-phase arrest and increased expression of stress-sensitive p53 and p16 proteins in normal human oral keratinocytes and fibroblasts. (external link)
-
Gausdal, Gro; Gjertsen, Bjørn Tore; McCormack, Emmet Martin
et al. (2008). Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death. (external link)
2007
-
Ånensen, Nina; Øyan, Anne Margrete; Huseby, Sjur
et al. (2007). Early gene expression of acute myeloid leukemia in response to chemotherapy. (external link)
-
Gjertsen, Bjørn Tore; Bredholt, Therese; Ånensen, Nina
et al. (2007). Bcl-2 antisense in the treatment of human malignancies: A delusion in targeted therapy. (external link)
-
Øyan, Anne Margrete; Bø, Trond Hellem; Jonassen, Inge
et al. (2007). Global gene expression in classification, pathogenetic understanding and identification of therapeutic targets in Acute Myeloid Leukemia. (external link)
-
Hagland, Hanne; Nikolaisen, Julie; Hodneland, Linn Iren
et al. (2007). Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling. (external link)
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Parlati, Francesco; Aujay, Monette; Bedringaas, Siv Lise
et al. (2007). Anti-tumor activity of immunoproteasome selective inhibitors. (external link)
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Stapnes, Camilla I; Ryningen, Anita; Hatfield, Kimberley Joanne
et al. (2007). Linking susceptibility to histone deactylase inhibitors and basal gene expression profiles in acute myeloid leukaemia. (external link)
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Stapnes, Camilla I; Ryningen, Anita; Hatfield, Kimberley Joanne
et al. (2007). Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in the susceptibility to histone deacetylase inhibitors. (external link)
See a complete overview of publications in Cristin.