KG Jebsen Center for Diabetes Research

Elite diabetes scientist to the University of Bergen

The Toppforskprogramme at UiB

Academic article

• Suzuki, Ken; Hatzikotoulas, Konstantinos; Southam, Lorraine et al. (2024). Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. (external link)
• Akerlund, Mikael; Baskozos, Georgios; Li, Wenqianglong et al. (2024). Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort. (external link)
• Bjarkø, Vera Vik; Haug, Eirin Beate; Langhammer, Arnulf et al. (2024). Clinical utility of novel diabetes subgroups in predicting vascular complications and mortality: up to 25 years of follow-up of the HUNT Study. (external link)
• Slieker, Roderick C.; Donnelly, Louise A.; Akalestou, Elina et al. (2023). Identification of biomarkers for glycaemic deterioration in type 2 diabetes. (external link)
• Yengo, Loïc; Vedantam, Sailaja; Marouli, Eirini et al. (2022). A saturated map of common genetic variants associated with human height. (external link)
• Keindl, Magdalena; Davies, Richard Allan; Bergum, Brith et al. (2022). Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren’s syndrome. (external link)
• Mahajan, Anubha; Spracklen, Cassandra N.; Zhang, Weihua et al. (2022). Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. (external link)
• Fedotkina, Olena; Jain, Ruchi; Prasad, Rashmi B. et al. (2022). Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes. (external link)
• Fernandez, Manuel Carrasco; Wang, Chencheng; Søviknes, Anne Mette et al. (2022). Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. (external link)
• Ramdas, Shweta; Judd, Jonathan; Graham, Sarah E. et al. (2022). A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. (external link)
• Hindy, George; Dornbos, Peter; Chaffin, Mark D. et al. (2022). Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes. (external link)
• Kanoni, Stavroula; Graham, Sarah E.; Wang, Yuxuan et al. (2022). Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. (external link)
• Lagou, Vasiliki; Mägi, Reedik; Hottenga, Jouke- Jan et al. (2021). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. (external link)
• Fedotkina, Olena; Luk, Andrea O.Y.; Jain, Ruchi et al. (2021). Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes. (external link)
• Chen, Ji; Spracklen, Cassandra N.; Marenne, Gaëlle et al. (2021). The trans-ancestral genomic architecture of glycemic traits. (external link)
• Fedotkina, Olena; Sulaieva, Oksana; Özgümüs, Türküler et al. (2021). Novel Reclassification of Adult Diabetes Is Useful to Distinguish Stages of β-Cell Function Linked to the Risk of Vascular Complications: The DOLCE Study From Northern Ukraine. (external link)
• Slieker, Roderick C.; Donnelly, Louise A.; Fitipaldi, Hugo et al. (2021). Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study. (external link)
• Goodrich, Julia K.; Singer-Berk, Moriel; Son, Rachel et al. (2021). Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. (external link)
• Slieker, Roderick C.; Donnelly, Louise A.; Fitipaldi, Hugo et al. (2021). Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study. (external link)
• Özgümüs, Türküler; Sulaieva, Oksana; Jessen, Leon E. et al. (2021). Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study. (external link)
• Özgümüs, Türküler; Sulaieva, Oksana; Jain, Ruchi et al. (2021). Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells. (external link)
• Graham, Sarah E.; Clarke, Shoa L.; Wu, Kuan-Han H. et al. (2021). The power of genetic diversity in genome-wide association studies of lipids. (external link)
• Keindl, Magdalena; Fedotkina, Olena; Plessis, Elsa du et al. (2020). Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms. (external link)
• Jain, Ruchi; Özgümüs, Türküler; Jensen, Troels Mygind et al. (2020). Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes. (external link)
• Lyssenko, Valeriya (2020). Koble. (external link)
• Pollack, Samuela; Igo, Robert P.; Jensen, Richard A. et al. (2019). Multiethnic genome-wide association study of diabetic retinopathy using liability threshold modeling of duration of diabetes and glycemic control. (external link)
• Flannick, Jason; Mercader, Josep M.; Fuchsberger, Christian et al. (2019). Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. (external link)
• Zuydam, Natalie R. van; Ahlqvist, Emma; Sandholm, Niina et al. (2018). A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes. (external link)
• Mahajan, Anubha; Taliun, Daniel; Thurner, Matthias et al. (2018). Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. (external link)
• Flannick, Jason; Fuchsberger, Christian; Mahajan, Anubha et al. (2017). Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. (external link)
• Wheeler, Eleanor; Leong, Aaron; Liu, Ching-Ti et al. (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. (external link)
• Olesen, Kasper; Jensen, Troels Mygind; Diaz, Lars Jorge et al. (2017). Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes - The PROLONG-Steno study. (external link)
• Fuchsberger, Christian; Flannick, Jason; Teslovich, Tanya M. et al. (2016). The genetic architecture of type 2 diabetes. (external link)
• Ried, Janina S.; Jeff, Janina M.; Chu, Audrey Y. et al. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. (external link)
• Shungin, Dmitry; Winkler, Thomas W.; Croteau-Chonka, Damien C. et al. (2015). New genetic loci link adipose and insulin biology to body fat distribution. (external link)
• Locke, Adam E.; Kahali, Bratati; Berndt, Sonja I. et al. (2015). Genetic studies of body mass index yield new insights for obesity biology. (external link)
• Wood, Andrew R.; Esko, Tonu; Yang, Jian et al. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. (external link)
• Mahajan, Anubha; Go, Min Jin; Zhang, Weihua et al. (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. (external link)
• Flannick, Jason; Beer, Nicola L.; Bick, Alexander G. et al. (2013). Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. (external link)
• Morris, AP; Voight, BF; Teslovich, TM et al. (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. (external link)
• Hertel, Jens Kristoffer; Johansson, Stefan; Sonestedt, Emily et al. (2011). FTO, type 2 diabetes, and weight gain throughout adult life A meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies. (external link)
• Voight, BF; Scott, LJ; Steinthorsdottir, V et al. (2010). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. (external link)
• Zeggini, E; Scott, LJ; Saxena, R et al. (2008). Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. (external link)
• Hertel, Jens Kristoffer; Johansson, Stefan; Ræder, H et al. (2008). Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study). (external link)

Errata

• Graham, Sarah E.; Clarke, Shoa L.; Wu, Kuan-Han H. et al. (2023). Author Correction: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3). (external link)
• Lagou, Vasiliki; Mägi, Reedik; Hottenga, Jouke- Jan et al. (2021). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9). (external link)

Academic literature review

• Lyssenko, Valeriya; Vaag, Allan (2023). Genetics of diabetes-associated microvascular complications. (external link)
• Salanti, G; Southam, L; Altshuler, D et al. (2009). Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations. (external link)

See a complete overview of publications in Cristin.