- karianne.fjeld@uib.no
- Visitor address
-
Haukeland University Hospital The Laboratory Building, 9th floor
5009 Bergen - Room: 8480
- Postal address
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P.O. Box 7804NO-5020 BergenNorway
Research
- Pancreatitis
- Pancreatic cancer
- Mody-diabetes (monogenic diabetes)
Affiliated with the following reasearch groups:
https://www.uib.no/en/diabetes
https://pancreas.w.uib.no
Publications
Academic article
- Inger Hals Kvinnsland; Keijo Aukusti Luukko; Inge Fristad et al. (2004). Glial cell line-derived neurotrophic factor (GDNF) from adult rat tooth serves a distinct population of large-sized trigeminal neurons. (external link)
- Janniche Torsvik; Bente Berg Johansson; Monica Dalva et al. (2014). Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction. (external link)
- Karianne Fjeld; Frank Ulrich Weiss; Denise Lasher et al. (2015). A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. (external link)
- Kelly Velasco Pinto; Johanna Lüdeke St-Louis; Henrikke Nilsen Hovland et al. (2020). Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro. (external link)
- Khadija el Jellas; Petra Dušátková; Ingfrid S. Haldorsen et al. (2022). Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases. (external link)
- Anny Gravdal Svanbring; Steven J. Wilhelm; Ivan Abbedissen et al. (2025). The MODY-Causing Mutation of the Human Carboxyl Ester Lipase Gene (CEL) Triggers Chronic Pancreatitis But Not Diabetes in Mice. (external link)
- Khadija el Jellas; Bente Berg Johansson; Karianne Fjeld et al. (2018). The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants. (external link)
- Monica Dalva Valvatne; Ida Marie Kjærefjord Lavik; Khadija el Jellas et al. (2020). Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells. (external link)
- Brett M. Cassidy; Sammy Zino; Karianne Fjeld et al. (2020). Single nucleotide polymorphisms in CEL-HYB1 increase risk for chronic pancreatitis through proteotoxic misfolding. (external link)
- Ranveig Seim Brekke; Anny Gravdal Svanbring; Khadija el Jellas et al. (2024). Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas. (external link)
- Paivi Kettunen; Sigbjørn Suk Løes; Tomasz Michal Furmanek et al. (2005). Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfβ1 regulate semaphorin 3a expression in the dental mesenchyme. (external link)
- Monica Dalva; Khadija el Jellas; Solrun Steine et al. (2017). Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer. (external link)
- Matthew J. Kolar; Siddhesh S. Kamat; William H. Parsons et al. (2016). Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. (external link)
- Anja Ragvin; Karianne Fjeld; F. Ulrich Weiss et al. (2013). The number of tandem repeats in the carboxyl-ester lipase (CEL) gene as a risk factor in alcoholic and idiopathic chronic pancreatitis. (external link)
- Karianne Fjeld; Paivi Kettunen; Tomasz Michal Furmanek et al. (2005). Dynamic expression of Wnt signaling-related Dickkopf1,-2, and-3 mRNAs in the developing mouse tooth. (external link)
- Karianne Fjeld; Anny Gravdal Svanbring; Ranveig Seim Brekke et al. (2022). The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice. (external link)
- Anny Gravdal Svanbring; Xunjun Xiao; Miriam Cnop et al. (2021). The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity. (external link)
- Keijo Luukko; Sigbjørn Suk Løes; Tomasz Furmanek et al. (2003). Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. (external link)
- Xuguang Nie; Keijo Luukko; Karianne Fjeld et al. (2005). Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice. (external link)
- Inge Fristad; Vaska Vandevska-Radunovic; Karianne Fjeld et al. (2003). NK1-, NK2-, NK3-, and CGRP1-receptors identified in rat oral soft tissues, bone- and hard tissue cells. (external link)
- Grzegorz Oracz; Aleksandra Anna Kujko; Karianne Fjeld et al. (2019). The hybrid allele 1 of carboxyl-ester lipase (CEL-HYB1) in Polish pediatric patients with chronic pancreatitis. (external link)
- Keijo Aukusti Luukko; Sigbjorn Loes; Tomasz Furmanek et al. (2003). Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. (external link)
- Bente Berg Johansson; Karianne Fjeld; Marie Holm Solheim et al. (2017). Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation. (external link)
- Henrik Underthun Irgens; Karianne Fjeld; Bente Berg Johansson et al. (2015). Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release. (external link)
- Karianne Fjeld; Sebastian Beer; Marianne Johnstone et al. (2016). Length of variable numbers of tandem repeats in the carboxyl ester lipase (CEL) gene may confer susceptibility to alcoholic liver cirrhosis but not alcoholic chronic pancreatitis. (external link)
- Erling Tjora; Anny Gravdal; Trond Engjom et al. (2021). Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis. (external link)
- Karianne Fjeld; Emmanuelle Masson; Jin-Huan Lin et al. (2020). Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis. (external link)
- Bente Berg Johansson; Janniche Torsvik; Lise Bjørkhaug et al. (2011). Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY) A PROTEIN MISFOLDING DISEASE. (external link)
Doctoral thesis (PhD)
Media feature article
Conference abstract
- Karianne Fjeld; Janniche Torsvik; Stefan Johansson et al. (2008). Structural changes in the repeated region of the carboxyl-ester lipase (CEL) gene and the development of diabetes. (external link)
- Anders Molven; Janniche Torsvik; Bente Berg Johansson et al. (2013). Cellular re-uptake of secreted carboxyl-ester lipase protein in CEL-MODY, a syndrome of diabetes and pancreatic exocrine dysfunction. (external link)
Master’s thesis
- Diego Iglesias Lopez; Anders Molven; Nils Henrik Halberg et al. (2024). Interplay of the proteotoxic CEL-MODY protein and oncogenic KRAS in pancreatic cancer development. (external link)
- Karianne Fjeld (2000). The effect of Beta1-integrins on the invasive phenotype of human gliomas. (external link)
- Karianne Fjeld (2000). The effect of beta1-integins on the phenotype of human gliomas. (external link)