Academic article
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Lars Herfindal; Lene Elisabeth Myhren; Bjørn Tore Gjertsen
et al. (2013). Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen. (external link)
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Etienne Auvert; Reidun Aesoy; Francis Giraud
et al. (2022). Synthesis of new pyrazolo[4,3-a]phenanthridine Pim-1 inhibitors and evaluation of their cytotoxic activity towards the MOLM-13 acute myeloid leukemia cell line. (external link)
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Jan-Lukas Førde; Ingeborg Nerbø Reiten; Kari Espolin Fladmark
et al. (2022). A new software tool for computer assisted in vivo high-content analysis of transplanted fluorescent cells in intact zebrafish larvae. (external link)
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Maria Teresa Bezem; Fredrik Gullaksen Johannessen; Kunwar Jung K C
et al. (2018). Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. (external link)
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Frode Selheim; Lars Herfindal; Gjert Knutsen
et al. (2001). Alterations in platelet phospholipid metabolism by substances from a marine microalgae. (external link)
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Ayaan Hamdi Haji Ibrahim; Lars Herfindal; Bendik Auran Rathe
et al. (2019). A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae). (external link)
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Hanne Jørgensen; Kristin Degnes; Håvard Sletta
et al. (2009). Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. (external link)
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Linn Silje Wathne Oftedal; Kaja Helvik Skjærven; Rosie Theresa Coyne
et al. (2011). The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. (external link)
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Ronja Bjørnstad; Ingeborg Nerbø Reiten; Kaja Skålnes Knudsen
et al. (2022). A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect. (external link)
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Elvar Örn Viktorsson; Reidun Aesoy; Sindre Støa
et al. (2021). New prodrugs and analogs of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells. (external link)
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Agnete Engelsen; Katarzyna Wnuk-Lipinska; Sébastien Bougnaud
et al. (2020). AXL is a driver of stemness in normal mammary gland and breast cancer. (external link)
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Rita Calisto; Eirik Færøy Sæbø; Julia Endresen Storesund
et al. (2019). Anticancer activity in Planctomycetes. (external link)
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Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal
(2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (external link)
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Kathrine Sivertsen Åsrud; Line Pedersen; Reidun Aesoy
et al. (2019). Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. (external link)
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Gro Gausdal; Anita Wergeland; Jørn Skavland
et al. (2013). Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. (external link)
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Anu Humisto; Jouni Jokela; Knut Teigen
et al. (2019). Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes. (external link)
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Bjørn Tobiassen Heieren; Anja Strandvoll Dyrdal; Lars Herfindal
et al. (2024). Cytotoxic Natural Products from Cryptomeria japonica (Thunb. ex L.) D.Don. (external link)
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Goraksha Machhindra Khose; Siva Krishna Vagolu; Reidun Aesoy
et al. (2025). Functionalized regioisomers of the natural product phenazines myxin and iodinin as potent inhibitors of Mycobacterium tuberculosis and human acute myeloid leukemia cells. (external link)
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Zhiqiang Wang; David Landy; Christina Sizun
et al. (2020). Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine. (external link)
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Gyrid Nygaard; Lars Herfindal; Reidun Kristin Kopperud
et al. (2014). Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. (external link)
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Lars Herfindal; Frode Selheim; Linn Silje Wathne Oftedal
et al. (2005). A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes. (external link)
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Zouhair Bouaziz; Samar Issa; Jacques Gentili
et al. (2015). Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. (external link)
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Frode Selheim; Lars Herfindal; Rosario Martins
et al. (2005). Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. (external link)
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Anu Humisto; Lars Herfindal; Jouni Jokela
et al. (2016). Cyanobacteria as a source for novel anti-leukemic compounds. (external link)
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Christelle Marminon; Christian Werner; Alexander Gast
et al. (2025). Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2. (external link)
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Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bendik Auran Rathe
et al. (2019). Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. (external link)
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Håvard Sletta; Kristin Fløgstad Degnes; Lars Herfindal
et al. (2014). Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment. (external link)
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Rosário F. Martins; Miguel F. Ramos; Lars Herfindal
et al. (2008). Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and synechococcus. (external link)
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Edvin Tang Gundersen; Zhiqiang Wang; Jan-Lukas Førde
et al. (2025). Repurposing chlorpromazine for anti-leukaemic therapy with the drug-in-cyclodextrin-in-liposome nanocarrier platform. (external link)
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Angeliki Barouti; Le Ba Vinh; Lars Herfindal
et al. (2026). Marine Bromophenols from Laminaria hyperborea’s Epiphytic Biomass: Chemical Profiling, Cytotoxicity, and Antioxidant Activity. (external link)
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Liwei Liu; Jouni Jokela; Lars Herfindal
et al. (2014). 4-methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides. (external link)
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Luc Augis; Ingeborg Nerbø Reiten; Jan-Lukas Førde
et al. (2024). Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances. (external link)
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Angeliki Barouti; Lars Herfindal; Siva Krishna Vagolu
et al. (2024). Evaluation of the cytotoxic and antimicrobial potential of epiphytic biomass obtained from Laminaria hyperborea biorefinery side-streams. (external link)
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Abdelnour Alhourani; Jan-Lukas Førde; Lutz Andreas Eichacker
et al. (2021). Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide. (external link)
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Jan-Lukas Førde; Lars Herfindal; Kjell-Morten Myhr
et al. (2023). Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro. (external link)
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Anthony Prandina; Lars Herfindal; Sylvie Radix
et al. (2018). Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles. (external link)
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Anne Oldeide Hay; Roger Trones; Lars Herfindal
et al. (2022). Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. (external link)
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Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal
(2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (external link)
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Camilla Krakstad; Lars Herfindal; Bjørn Tore Gjertsen
et al. (2006). CaM-kinasell-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. (external link)
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Francis Giraud; Marion Bourhis; Lionel Nauton
et al. (2014). New N-1,N-10 bridged pyrrolo[2,3-α]carbazole-3-carbaldehydes: synthesis and biological activities. (external link)
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Aase Merethe Raddum; Quynh Bao Truong Le; Lars Herfindal
et al. (2025). Fostering student agency and confidence through problem-based learning and cognitive reflection in the pharmaceutics laboratory. (external link)
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Edvin Tang Gundersen; Jan-Lukas Førde; Benedicte Sjo Tislevoll
et al. (2021). Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation. (external link)
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Rune Slimestad; Bendik Auran Rathe; Reidun Aesoy
et al. (2022). A novel bicyclic lactone and other polyphenols from the commercially important vegetable Anthriscus cerefolium. (external link)
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Ingeborg Nerbø Reiten; Reidun Æsøy; Jan-Lukas Førde
et al. (2025). Phenazine 5,10-dioxide analogues as potential therapeutics in AML: Efficacy on patient-derived blasts, in zebrafish larvae xenografts and synergy with venetoclax. (external link)
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Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Heidi Lie Andersen
et al. (2023). Cytotoxic Natural Products Isolated from Cryptogramma crispa (L.) R. Br.. (external link)
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Lars Herfindal; Gyrid Nygaard; Reidun Kristin Kopperud
et al. (2013). Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. (external link)
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Siv Kristin Prestegard; Linn Silje Wathne Oftedal; Rosie Theresa Coyne
et al. (2009). Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity. (external link)
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Jouni Jokela; Lars Herfindal; Matti Wahlsten
et al. (2010). A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins. (external link)
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Liwei Liu; Lars Herfindal; Jouni Jokela
et al. (2014). Cyanobacteria from terrestrial and marine sources contain apoptogens able to overcome chemoresistance in acute myeloid leukemia cells. (external link)
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Gyrid Nygaard; Lars Herfindal; Kathrine Sivertsen Åsrud
et al. (2017). Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. (external link)
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Elvar Örn Viktorsson; Bendik Melling Grøthe; Reidun Aesoy
et al. (2017). Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. (external link)
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Lasse Evensen; Patrick Lie Johansen; Gerbrand Koster
et al. (2016). Zebrafish as a model system for characterization of nanoparticles against cancer. (external link)
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Jouni Jokela; Linn Silje Wathne Oftedal; Lars Herfindal
et al. (2012). Anabaenolysins, novel cytolytic lipopeptides from benthic anabaena cyanobacteria. (external link)
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Linn Silje Wathne Oftedal; Lene Elisabeth Myhren; Jouni Jokela
et al. (2012). The lipopeptide toxins Anabaenolysin A and B target biological membranes in a cholesterol-dependent manner. (external link)
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Eirik Johansson Solum; Trond Vidar Hansen; Reidun Aesoy
et al. (2020). New CDK8 inhibitors as potential anti-leukemic agents – Design, synthesis and biological evaluation. (external link)
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Ingeborg Nerbø Reiten; Francis Giraud; Tuva Torblå Augedal
et al. (2025). Liposomes loaded with daunorubicin and an emetine prodrug for improved selective cytotoxicity towards acute myeloid leukaemia cells. (external link)
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Jan-Lukas Førde; Abdelnour Alhourani; Tian Carey
et al. (2024). Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation. (external link)
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Lars Herfindal; Franciszek Kasprzykowski; Frank Schwede
et al. (2009). Acyloxymethyl esterification of Nodularin-R and Microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells. (external link)
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Linn Silje Wathne Oftedal; Frode Selheim; Matti Wahlsten
et al. (2010). Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes. (external link)
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Lene Elisabeth Myhren; Gyrid Nygaard; Gro Gausdal
et al. (2013). Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. (external link)
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Anette Lodvir Hemsing; Jan-Lukas Førde; Håkon Reikvam
et al. (2024). The Rac1-inhibitor EHop-016 attenuates AML cell migration and enhances the efficacy of daunorubicin in MOLM-13 transplanted zebrafish larvae. (external link)
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Øystein Bruserud; Nils Glenjen; Bjørn Tore Gjertsen
et al. (2002). Use of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells. (external link)
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Mohummad Aminur Rahman; Jorunn Brekke; Victoria Smith Arnesen
et al. (2020). Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study. (external link)
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Théo Frazier; Elisabeth Pereira; Reidun Aesoy
et al. (2024). Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles. (external link)
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Abdelnour Alhourani; Jan-Lukas Førde; Mojdeh Nasrollahzadeh
et al. (2022). Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish. (external link)
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Tania Keiko Shishido; Rafael Vicentini Popin; Jouni Jokela
et al. (2019). Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria. (external link)
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Lene Elisabeth Myhren; Ida Mostrøm Nilssen; Valérie Nicolas
et al. (2014). Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia. (external link)
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Francis Giraud; Marion Bourhis; Edris Ebrahimi
et al. (2015). Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells. (external link)
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Ronja Bjørnstad; Reidun Aesoy; Øystein Bruserud
et al. (2019). A kinase inhibitor with anti-Pim kinase activity is a potent and selective cytotoxic agent toward acute myeloid leukemia. (external link)
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Marita Hoang Anh Vu; Lars Herfindal; Ole-Johan Juvik
et al. (2016). Toxic aromatic compounds from fruits of Narthecium ossifragum L.. (external link)
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Lars Herfindal; Camilla Krakstad; Lene Elisabeth Myhren
et al. (2014). Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. (external link)
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Yagut Allahverdiyeva; Eva-Mari Aro; Bert van Bavel
et al. (2021). NordAqua, a Nordic Center of Excellence to develop an algae-based photosynthetic production platform. (external link)
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Lars Herfindal; Lene Elisabeth Myhren; Rune Kleppe
et al. (2011). Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. (external link)
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Kari Skjånes; Reidun Aesoy; Lars Herfindal
et al. (2021). Bioactive peptides from microalgae: Focus on anti-cancer and immunomodulating activity. (external link)
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Trond T. Serkland; Jan Schjøtt; Jon Andsnes Berg
et al. (2019). Short communication: Distribution of psychotropic drugs into lipoproteins. (external link)
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Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bjarte Holmelid
et al. (2024). Cytotoxic Natural Products from the Jurassic Relict Osmunda regalis L.. (external link)
Conference poster
Master’s thesis
Lecture
Popular science article
Conference lecture
Media interview
Academic literature review
Editorial/Leader article
Conference abstract
Research report
Academic book chapter
Doctoral thesis (PhD)
Professional article
See a complete overview of publications in Cristin.