Academic article
-
Théo Frazier; Elisabeth Pereira; Reidun Æsøy
et al. (2026). Synthesis, anti-cancer activity, Pim-3 inhibitory potency and zebrafish larvae toxicity evaluation of indolopyrazolocarbazole derivatives. (external link)
-
Angeliki Barouti; Le Ba Vinh; Lars Herfindal
et al. (2026). Marine Bromophenols from Laminaria hyperborea’s Epiphytic Biomass: Chemical Profiling, Cytotoxicity, and Antioxidant Activity. (external link)
-
Edvin Tang Gundersen; Zhiqiang Wang; Jan-Lukas Førde
et al. (2025). Repurposing chlorpromazine for anti-leukaemic therapy with the drug-in-cyclodextrin-in-liposome nanocarrier platform. (external link)
-
Ingeborg Nerbø Reiten; Reidun Æsøy; Jan-Lukas Førde
et al. (2025). Phenazine 5,10-dioxide analogues as potential therapeutics in AML: Efficacy on patient-derived blasts, in zebrafish larvae xenografts and synergy with venetoclax. (external link)
-
Goraksha Machhindra Khose; Siva Krishna Vagolu; Reidun Aesoy
et al. (2025). Functionalized regioisomers of the natural product phenazines myxin and iodinin as potent inhibitors of Mycobacterium tuberculosis and human acute myeloid leukemia cells. (external link)
-
Christelle Marminon; Christian Werner; Alexander Gast
et al. (2025). Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2. (external link)
-
Ingeborg Nerbø Reiten; Francis Giraud; Tuva Torblå Augedal
et al. (2025). Liposomes loaded with daunorubicin and an emetine prodrug for improved selective cytotoxicity towards acute myeloid leukaemia cells. (external link)
-
Aase Merethe Raddum; Quynh Bao Truong Le; Lars Herfindal
et al. (2025). Fostering student agency and confidence through problem-based learning and cognitive reflection in the pharmaceutics laboratory. (external link)
-
Luc Augis; Ingeborg Nerbø Reiten; Jan-Lukas Førde
et al. (2024). Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances. (external link)
-
Angeliki Barouti; Lars Herfindal; Siva Krishna Vagolu
et al. (2024). Evaluation of the cytotoxic and antimicrobial potential of epiphytic biomass obtained from Laminaria hyperborea biorefinery side-streams. (external link)
-
Anette Lodvir Hemsing; Jan-Lukas Førde; Håkon Reikvam
et al. (2024). The Rac1-inhibitor EHop-016 attenuates AML cell migration and enhances the efficacy of daunorubicin in MOLM-13 transplanted zebrafish larvae. (external link)
-
Bjørn Tobiassen Heieren; Anja Strandvoll Dyrdal; Lars Herfindal
et al. (2024). Cytotoxic Natural Products from Cryptomeria japonica (Thunb. ex L.) D.Don. (external link)
-
Théo Frazier; Elisabeth Pereira; Reidun Aesoy
et al. (2024). Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles. (external link)
-
Jan-Lukas Førde; Abdelnour Alhourani; Tian Carey
et al. (2024). Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation. (external link)
-
Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bjarte Holmelid
et al. (2024). Cytotoxic Natural Products from the Jurassic Relict Osmunda regalis L.. (external link)
-
Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Heidi Lie Andersen
et al. (2023). Cytotoxic Natural Products Isolated from Cryptogramma crispa (L.) R. Br.. (external link)
-
Jan-Lukas Førde; Lars Herfindal; Kjell-Morten Myhr
et al. (2023). Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro. (external link)
-
Etienne Auvert; Reidun Aesoy; Francis Giraud
et al. (2022). Synthesis of new pyrazolo[4,3-a]phenanthridine Pim-1 inhibitors and evaluation of their cytotoxic activity towards the MOLM-13 acute myeloid leukemia cell line. (external link)
-
Jan-Lukas Førde; Ingeborg Nerbø Reiten; Kari Espolin Fladmark
et al. (2022). A new software tool for computer assisted in vivo high-content analysis of transplanted fluorescent cells in intact zebrafish larvae. (external link)
-
Ronja Bjørnstad; Ingeborg Nerbø Reiten; Kaja Skålnes Knudsen
et al. (2022). A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect. (external link)
-
Abdelnour Alhourani; Jan-Lukas Førde; Mojdeh Nasrollahzadeh
et al. (2022). Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish. (external link)
-
Anne Oldeide Hay; Roger Trones; Lars Herfindal
et al. (2022). Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. (external link)
-
Rune Slimestad; Bendik Auran Rathe; Reidun Aesoy
et al. (2022). A novel bicyclic lactone and other polyphenols from the commercially important vegetable Anthriscus cerefolium. (external link)
-
Abdelnour Alhourani; Jan-Lukas Førde; Lutz Andreas Eichacker
et al. (2021). Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide. (external link)
-
Elvar Örn Viktorsson; Reidun Aesoy; Sindre Støa
et al. (2021). New prodrugs and analogs of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells. (external link)
-
Yagut Allahverdiyeva; Eva-Mari Aro; Bert van Bavel
et al. (2021). NordAqua, a Nordic Center of Excellence to develop an algae-based photosynthetic production platform. (external link)
-
Kari Skjånes; Reidun Aesoy; Lars Herfindal
et al. (2021). Bioactive peptides from microalgae: Focus on anti-cancer and immunomodulating activity. (external link)
-
Edvin Tang Gundersen; Jan-Lukas Førde; Benedicte Sjo Tislevoll
et al. (2021). Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation. (external link)
-
Zhiqiang Wang; David Landy; Christina Sizun
et al. (2020). Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine. (external link)
-
Mohummad Aminur Rahman; Jorunn Brekke; Victoria Smith Arnesen
et al. (2020). Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study. (external link)
-
Agnete Engelsen; Katarzyna Wnuk-Lipinska; Sébastien Bougnaud
et al. (2020). AXL is a driver of stemness in normal mammary gland and breast cancer. (external link)
-
Eirik Johansson Solum; Trond Vidar Hansen; Reidun Aesoy
et al. (2020). New CDK8 inhibitors as potential anti-leukemic agents – Design, synthesis and biological evaluation. (external link)
-
Kathrine Sivertsen Åsrud; Line Pedersen; Reidun Aesoy
et al. (2019). Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy. (external link)
-
Anu Humisto; Jouni Jokela; Knut Teigen
et al. (2019). Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes. (external link)
-
Ayaan Hamdi Haji Ibrahim; Lars Herfindal; Bendik Auran Rathe
et al. (2019). A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae). (external link)
-
Tania Keiko Shishido; Rafael Vicentini Popin; Jouni Jokela
et al. (2019). Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria. (external link)
-
Ronja Bjørnstad; Reidun Aesoy; Øystein Bruserud
et al. (2019). A kinase inhibitor with anti-Pim kinase activity is a potent and selective cytotoxic agent toward acute myeloid leukemia. (external link)
-
Rita Calisto; Eirik Færøy Sæbø; Julia Endresen Storesund
et al. (2019). Anticancer activity in Planctomycetes. (external link)
-
Andrea Estefania Carpinteyro Diaz; Lars Herfindal; Bendik Auran Rathe
et al. (2019). Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. (external link)
-
Trond T. Serkland; Jan Schjøtt; Jon Andsnes Berg
et al. (2019). Short communication: Distribution of psychotropic drugs into lipoproteins. (external link)
-
Maria Teresa Bezem; Fredrik Gullaksen Johannessen; Kunwar Jung K C
et al. (2018). Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. (external link)
-
Anthony Prandina; Lars Herfindal; Sylvie Radix
et al. (2018). Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles. (external link)
-
Gyrid Nygaard; Lars Herfindal; Kathrine Sivertsen Åsrud
et al. (2017). Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. (external link)
-
Elvar Örn Viktorsson; Bendik Melling Grøthe; Reidun Aesoy
et al. (2017). Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. (external link)
-
Anu Humisto; Lars Herfindal; Jouni Jokela
et al. (2016). Cyanobacteria as a source for novel anti-leukemic compounds. (external link)
-
Lasse Evensen; Patrick Lie Johansen; Gerbrand Koster
et al. (2016). Zebrafish as a model system for characterization of nanoparticles against cancer. (external link)
-
Marita Hoang Anh Vu; Lars Herfindal; Ole-Johan Juvik
et al. (2016). Toxic aromatic compounds from fruits of Narthecium ossifragum L.. (external link)
-
Francis Giraud; Marion Bourhis; Edris Ebrahimi
et al. (2015). Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells. (external link)
-
Zouhair Bouaziz; Samar Issa; Jacques Gentili
et al. (2015). Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. (external link)
-
Liwei Liu; Jouni Jokela; Lars Herfindal
et al. (2014). 4-methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides. (external link)
-
Gyrid Nygaard; Lars Herfindal; Reidun Kristin Kopperud
et al. (2014). Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. (external link)
-
Liwei Liu; Lars Herfindal; Jouni Jokela
et al. (2014). Cyanobacteria from terrestrial and marine sources contain apoptogens able to overcome chemoresistance in acute myeloid leukemia cells. (external link)
-
Lene Elisabeth Myhren; Ida Mostrøm Nilssen; Valérie Nicolas
et al. (2014). Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia. (external link)
-
Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal
(2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (external link)
-
Francis Giraud; Marion Bourhis; Lionel Nauton
et al. (2014). New N-1,N-10 bridged pyrrolo[2,3-α]carbazole-3-carbaldehydes: synthesis and biological activities. (external link)
-
Lars Herfindal; Camilla Krakstad; Lene Elisabeth Myhren
et al. (2014). Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. (external link)
-
Håvard Sletta; Kristin Fløgstad Degnes; Lars Herfindal
et al. (2014). Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment. (external link)
-
Siv Kristin Prestegard; Gjert Knutsen; Lars Herfindal
(2014). Adenosine content and growth in the diatom Phaeodactylum tricornutum (Bacillariophyceae): effect of salinity, light, temperature and nitrate. (external link)
-
Lars Herfindal; Lene Elisabeth Myhren; Bjørn Tore Gjertsen
et al. (2013). Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen. (external link)
-
Lene Elisabeth Myhren; Gyrid Nygaard; Gro Gausdal
et al. (2013). Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells. (external link)
-
Gro Gausdal; Anita Wergeland; Jørn Skavland
et al. (2013). Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. (external link)
-
Lars Herfindal; Gyrid Nygaard; Reidun Kristin Kopperud
et al. (2013). Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. (external link)
-
Jouni Jokela; Linn Silje Wathne Oftedal; Lars Herfindal
et al. (2012). Anabaenolysins, novel cytolytic lipopeptides from benthic anabaena cyanobacteria. (external link)
-
Linn Silje Wathne Oftedal; Lene Elisabeth Myhren; Jouni Jokela
et al. (2012). The lipopeptide toxins Anabaenolysin A and B target biological membranes in a cholesterol-dependent manner. (external link)
-
Linn Silje Wathne Oftedal; Kaja Helvik Skjærven; Rosie Theresa Coyne
et al. (2011). The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. (external link)
-
Lars Herfindal; Lene Elisabeth Myhren; Rune Kleppe
et al. (2011). Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. (external link)
-
Jouni Jokela; Lars Herfindal; Matti Wahlsten
et al. (2010). A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins. (external link)
-
Linn Silje Wathne Oftedal; Frode Selheim; Matti Wahlsten
et al. (2010). Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes. (external link)
-
Hanne Jørgensen; Kristin Degnes; Håvard Sletta
et al. (2009). Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. (external link)
-
Siv Kristin Prestegard; Linn Silje Wathne Oftedal; Rosie Theresa Coyne
et al. (2009). Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity. (external link)
-
Lars Herfindal; Franciszek Kasprzykowski; Frank Schwede
et al. (2009). Acyloxymethyl esterification of Nodularin-R and Microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells. (external link)
-
Rosário F. Martins; Miguel F. Ramos; Lars Herfindal
et al. (2008). Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and synechococcus. (external link)
-
Camilla Krakstad; Lars Herfindal; Bjørn Tore Gjertsen
et al. (2006). CaM-kinasell-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. (external link)
-
Lars Herfindal; Frode Selheim; Linn Silje Wathne Oftedal
et al. (2005). A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes. (external link)
-
Frode Selheim; Lars Herfindal; Rosario Martins
et al. (2005). Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. (external link)
-
Øystein Bruserud; Nils Glenjen; Bjørn Tore Gjertsen
et al. (2002). Use of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells. (external link)
-
Frode Selheim; Lars Herfindal; Gjert Knutsen
et al. (2001). Alterations in platelet phospholipid metabolism by substances from a marine microalgae. (external link)
Academic book chapter
Academic literature review
Conference abstract
Conference lecture
Conference poster
Doctoral thesis (PhD)
Editorial/Leader article
Lecture
Master’s thesis
Media interview
Popular science article
Professional article
Research report
See a complete overview of publications in NVA.